| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Adachi, D Browne, E J Lewi. Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine beta-hydroxylase gene transcription. DNA and cell biology. vol 19. issue 9. 2000-11-01. PMID:11034547. |
both proteins bind to three sites in the promoter proximal region of the rat dopamine beta-hydroxylase gene (dbh). |
2000-11-01 |
2023-08-12 |
mouse |
| H N Sabbah, W C Stanley, V G Sharov, T Mishima, M Tanimura, C R Benedict, S Hegde, S Goldstei. Effects of dopamine beta-hydroxylase inhibition with nepicastat on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure. Circulation. vol 102. issue 16. 2000-10-31. PMID:11034950. |
inhibition of dopamine beta-hydroxylase (dbh) results in a decrease in norepinephrine synthesis. |
2000-10-31 |
2023-08-12 |
Not clear |
| Z Y Tong, A E Kingsbury, O J Foste. Up-regulation of tyrosine hydroxylase mRNA in a sub-population of A10 dopamine neurons in Parkinson's disease. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925142. |
neither population expressed dopamine beta-hydroxylase (dbh). |
2000-10-04 |
2023-08-12 |
human |
| G W. The first, second, third and fourth order Markov chain analysis on the amino-acid sequence of human dopamine beta-hydroxylase. Molecular psychiatry. vol 5. issue 4. 2000-09-14. PMID:10889558. |
the repeated amino-acid sequences in human dopamine beta-hydroxylase (dbh) may be indispensable for dbh activity, because such repetitions cannot be simply attributed to random chance. |
2000-09-14 |
2023-08-12 |
human |
| F J Arrufat, R Diaz, R Queralt, V Navarro, T Marcos, G Massana, J Massana, F Ballesta, R Oliv. Analysis of the polymorphic (GT)(n) repeat at the dopamine beta-hydroxylase gene in Spanish patients affected by schizophrenia. American journal of medical genetics. vol 96. issue 1. 2000-09-07. PMID:10686559. |
the presence of a polymorphic (gt)(n) repeat, a microsatellite repeat, at the human dopamine beta-hydroxylase (dbh) gene had been previously investigated in healthy people and in schizophrenic patients. |
2000-09-07 |
2023-08-12 |
human |
| K C Lim, G Lakshmanan, S E Crawford, Y Gu, F Grosveld, J D Enge. Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. Nature genetics. vol 25. issue 2. 2000-06-29. PMID:10835639. |
we find here that null mutation of gata3 leads to reduced accumulation of th (encoding tyrosine hydroxylase, th) and dbh (dopamine beta-hydroxylase, dbh) mrna, whereas several other sns genes are unaffected. |
2000-06-29 |
2023-08-12 |
mouse |
| E Popovik, L W Hayne. Survival and mitogenesis of neuroepithelial cells are influenced by noradrenergic but not cholinergic innervation in cultured embryonic rat neopallium. Brain research. vol 853. issue 2. 2000-06-21. PMID:10640620. |
the projection of interconnecting fibres into germinal areas of the cortex was established in vitro by retrograde tracing and dopamine beta-hydroxylase (dbh) immunocytochemistry. |
2000-06-21 |
2023-08-12 |
rat |
| U Ernsberger, E Reissmann, I Mason, H Rohre. The expression of dopamine beta-hydroxylase, tyrosine hydroxylase, and Phox2 transcription factors in sympathetic neurons: evidence for common regulation during noradrenergic induction and diverging regulation later in development. Mechanisms of development. vol 92. issue 2. 2000-06-16. PMID:10727856. |
during differentiation of sympathetic neurons in chick embryos, tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) mrnas become detectable during the same developmental period and are both induced by bmp 4. |
2000-06-16 |
2023-08-12 |
chicken |
| M S Szczypka, M A Rainey, R D Palmite. Dopamine is required for hyperphagia in Lep(ob/ob) mice. Nature genetics. vol 25. issue 1. 2000-06-12. PMID:10802666. |
dopamine-deficient mice (dbh(th/+), th-/-; hereafter dd mice) cannot synthesize dopamine in dopaminergic neurons. |
2000-06-12 |
2023-08-12 |
mouse |
| D Weinshenker, N C Rust, N S Miller, R D Palmite. Ethanol-associated behaviors of mice lacking norepinephrine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 9. 2000-06-02. PMID:10777779. |
we took a genetic approach to determine the effect of ne depletion on ethanol-mediated behaviors by using dopamine beta-hydroxylase knockout (dbh -/-) mice that specifically lack the ability to synthesize ne. |
2000-06-02 |
2023-08-12 |
mouse |
| C E Gariepy, T Ohuchi, S C Williams, J A Richardson, M Yanagisaw. Salt-sensitive hypertension in endothelin-B receptor-deficient rats. The Journal of clinical investigation. vol 105. issue 7. 2000-05-22. PMID:10749572. |
genetic rescue of et(b)(sl/sl) rats from this developmental defect using a dopamine--hydroxylase (dbh)-et(b) transgene results in et(b)-deficient adult rats. |
2000-05-22 |
2023-08-12 |
rat |
| N Yukimasa, K Isobe, H Nagai, Y Takuwa, T Naka. Successive occupancy by immediate early transcriptional factors of the tyrosine hydroxylase gene TRE and CRE sites in PACAP-stimulated PC12 pheochromocytoma cells. Neuropeptides. vol 33. issue 6. 2000-04-04. PMID:10657527. |
we previously demonstrated that pituitary adenylate cyclase-activating polypeptide (pacap) coordinately upregulates the expression of the tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) genes by activating the cyclic amp (camp) and protein kinase c (pkc) signaling pathways. |
2000-04-04 |
2023-08-12 |
rat |
| J F Cubells, H R Kranzler, E McCance-Katz, G M Anderson, R T Malison, L H Price, J Gelernte. A haplotype at the DBH locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia. Molecular psychiatry. vol 5. issue 1. 2000-03-17. PMID:10673769. |
a haplotype at the dbh locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia. |
2000-03-17 |
2023-08-12 |
human |
| D J Swanson, M Adachi, E J Lewi. The homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine beta-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding protein. The Journal of biological chemistry. vol 275. issue 4. 2000-02-29. PMID:10644760. |
for the noradrenergic phenotype, these influences combine to activate the expression of the catecholaminergic biosynthetic enzymes tyrosine hydroxylase and dopamine beta-hydroxylase (dbh). |
2000-02-29 |
2023-08-12 |
rat |
| S J Oh, I B Kim, E J Lee, K Y Kim, H I Kim, M H Chu. Immunocytological localization of dopamine in the guinea pig retina. Cell and tissue research. vol 298. issue 3. 2000-02-09. PMID:10639746. |
we examined dopaminergic neurons in the guinea pig retina; antisera against tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), phenylethanolamine n-methyltransferase (pnmt) and an antiserum against gamma-aminobutyric acid (gaba) were used. |
2000-02-09 |
2023-08-12 |
Not clear |
| Y S Lee, G Raia, C Tönshoff, M J Evinge. Neural regulation of phenylethanolamine N-methyltransferase (PNMT) gene expression in bovine chromaffin cells differs from other catecholamine enzyme genes. Journal of molecular neuroscience : MN. vol 12. issue 1. 2000-02-03. PMID:10636470. |
because the 5'-upstream regions of the pnmt do not contain sequences analogous to those demonstrated to convey neural regulation to the tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) catecholamine-synthesizing enzyme genes, functional and biochemical analyses have been utilized to characterize pnmt promoter responses to cholinergic and depolarizing agents. |
2000-02-03 |
2023-08-12 |
cattle |
| P Szot, D Weinshenker, S S White, C A Robbins, N C Rust, P A Schwartzkroin, R D Palmite. Norepinephrine-deficient mice have increased susceptibility to seizure-inducing stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594079. |
seizure susceptibility was determined in the dopamine beta-hydroxylase null mutant (dbh -/-) mouse using four different convulsant stimuli: 2,2,2-trifluroethyl ether (flurothyl), pentylenetetrazol (ptz), kainic acid, and high-decibel sound. |
2000-01-06 |
2023-08-12 |
mouse |
| G Kirov, I Jones, F McCandless, N Craddock, M J Owe. Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5. Molecular psychiatry. vol 4. issue 6. 2000-01-03. PMID:10578238. |
family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: dbh, dat1, comt, drd2, drd3 and drd5. |
2000-01-03 |
2023-08-12 |
Not clear |
| G Kirov, I Jones, F McCandless, N Craddock, M J Owe. Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5. Molecular psychiatry. vol 4. issue 6. 2000-01-03. PMID:10578238. |
we conducted family-based association studies for polymorphisms at three genes involved in the metabolism of dopamine: dopamine transporter (dat1), dopamine-beta-hydroxylase (dbh) and catechol-o-methyl transferase (comt); and three dopamine receptors: drd2, drd3 and drd5. |
2000-01-03 |
2023-08-12 |
Not clear |
| C J Scott, J A Rawson, A M Pereira, I J Clark. Oestrogen receptors in the brainstem of the female sheep: relationship to noradrenergic cells and cells projecting to the medial preoptic area. Journal of neuroendocrinology. vol 11. issue 10. 1999-12-01. PMID:10520123. |
noradrenergic/adrenergic cells were identified by immunostaining for dopamine beta-hydroxylase (dbh). |
1999-12-01 |
2023-08-12 |
Not clear |