| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simi Vincent, David Robertso. The broader view: catecholamine abnormalities. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 12 Suppl 1. 2002-12-20. PMID:12102462. |
norepinephrine (ne), a vital neurotransmitter in both the central and peripheral nervous systems, is synthesized by dopamine beta-hydroxylase (dbh) through the oxidation of dopamine (da) to ne. |
2002-12-20 |
2023-08-12 |
Not clear |
| Simi Vincent, David Robertso. The broader view: catecholamine abnormalities. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 12 Suppl 1. 2002-12-20. PMID:12102462. |
biochemical features of the syndrome include elevated levels of dopamine, undetectable levels of dbh, undetectable tissue and circulating levels of ne and epinephrine. |
2002-12-20 |
2023-08-12 |
Not clear |
| Emily M Garland, Maureen K Hahn, Terry P Ketch, Nancy R Keller, Chun-Hyung Kim, Kwang-Soo Kim, Italo Biaggioni, John R Shannon, Randy D Blakely, David Robertso. Genetic basis of clinical catecholamine disorders. Annals of the New York Academy of Sciences. vol 971. 2002-12-16. PMID:12438171. |
in 1986, we reported a congenital syndrome of undetectable tissue and circulating levels of norepinephrine and epinephrine, elevated levels of dopamine, and absence of dopamine-beta-hydroxylase (dbh). |
2002-12-16 |
2023-08-12 |
Not clear |
| Aiveen Kirley, Ziarih Hawi, Grainne Daly, Mary McCarron, Celine Mullins, Niamh Millar, Irwin Waldman, Michael Fitzgerald, Michael Gil. Dopaminergic system genes in ADHD: toward a biological hypothesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 4. 2002-11-19. PMID:12377397. |
four dopamine related gene loci have been implicated, however: dat 1, drd 4, dbh, and drd 5. |
2002-11-19 |
2023-08-12 |
Not clear |
| David Weinshenker, Sylvia S White, Martin A Javors, Richard D Palmiter, Patricia Szo. Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo. Brain research. vol 946. issue 2. 2002-11-12. PMID:12137927. |
net levels are normal in dopamine beta-hydroxylase knockout (dbh -/-) mice that lack ne, demonstrating that the net does not require endogenous ne for appropriate regulation under physiological conditions. |
2002-11-12 |
2023-08-12 |
mouse |
| Maria Antonietta Casu, Dinuccio Dinucci, Giancarlo Colombo, Gian Luigi Gessa, Luca Pan. Reduced DAT- and DBH-immunostaining in the limbic system of Sardinian alcohol-preferring rats. Brain research. vol 948. issue 1-2. 2002-10-30. PMID:12383975. |
to this aim, we carried out the present immunohistochemistry study using two antibodies raised against dopamine beta-hydroxylase (dbh), the enzyme responsible for the conversion of dopamine into noradrenaline, and against the dopamine transporter (dat), as markers for noradrenergic and dopaminergic fibers, respectively. |
2002-10-30 |
2023-08-12 |
rat |
| Ingrid Blain, Patrick Slama, Michel Giorgi, Thierry Tron, Marius Réglie. Copper-containing monooxygenases: enzymatic and biomimetic studies of the O-atom transfer catalysis. Journal of biotechnology. vol 90. issue 2. 2002-10-09. PMID:12069196. |
this review reports our recent studies or the mechanism of o-atom transfer to a benzylic c-h bond promoted by dopamine beta-hydroxylase (dbh) and its biomimetic models. |
2002-10-09 |
2023-08-12 |
Not clear |
| Tibor Hajszán, Laszlo Zaborszk. Direct catecholaminergic-cholinergic interactions in the basal forebrain. III. Adrenergic innervation of choline acetyltransferase-containing neurons in the rat. The Journal of comparative neurology. vol 449. issue 2. 2002-08-27. PMID:12115685. |
by comparing the number and distribution of dopamine beta-hydroxylase (dbh)/cholinergic appositions, described earlier, with those of pnmt/cholinergic interactions in the basal forebrain, it can be concluded that a significant proportion of putative dbh/cholinergic contacts may represent adrenergic input. |
2002-08-27 |
2023-08-12 |
rat |
| C Gagnon, R Schatz, U Otten, H Thoene. Synthesis, subcellular distribution and turnover of dopamine beta-hydroxylase in organ cultures of sympathetic ganglia and adrenal medullae. Journal of neurochemistry. vol 27. issue 5. 2002-08-27. PMID:12170592. |
the fact that the half-life of membrane-bound dopamine beta-hydroxylase is markedly longer than that of the two soluble pools suggests that the single pools are not only independently supplied by newly-synthesized dbh but there is also no appreciable subsequent exchange between soluble and membrane-bound pools. |
2002-08-27 |
2023-08-12 |
rat |
| Fátima Adrio, Ramón Anadón, Isabel Rodríguez-Molde. Distribution of tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) immunoreactivity in the central nervous system of two chondrostean fishes (Acipenser baeri and Huso huso). The Journal of comparative neurology. vol 448. issue 3. 2002-08-21. PMID:12115709. |
distribution of tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) immunoreactivity in the central nervous system of two chondrostean fishes (acipenser baeri and huso huso). |
2002-08-21 |
2023-08-12 |
Not clear |
| Tatiana Roman, Marcelo Schmitz, Guilherme V Polanczyk, Mariana Eizirik, Luis A Rohde, Mara H Hut. Further evidence for the association between attention-deficit/hyperactivity disorder and the dopamine-beta-hydroxylase gene. American journal of medical genetics. vol 114. issue 2. 2002-07-19. PMID:11857576. |
the dbh gene, the locus that encodes the enzyme dopamine-beta-hydroxylase (dbetah), seems to be an important candidate gene for association studies, since dbetah catalyzes the conversion of dopamine to norepinephrine. |
2002-07-19 |
2023-08-12 |
Not clear |
| Megumi Adachi, Elaine J Lewi. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status. The Journal of biological chemistry. vol 277. issue 25. 2002-07-19. PMID:11943777. |
the homeodomain transcription factor arix/phox2a plays a critical role in the specification of noradrenergic neurons by inducing the expression of dopamine beta-hydroxylase (dbh), the terminal enzyme for noradrenaline biosynthesis. |
2002-07-19 |
2023-08-12 |
Not clear |
| Karen Wigg, Gwyneth Zai, Russell Schachar, Rosemary Tannock, Wendy Roberts, Molly Malone, James L Kennedy, Cathy L Bar. Attention deficit hyperactivity disorder and the gene for dopamine Beta-hydroxylase. The American journal of psychiatry. vol 159. issue 6. 2002-06-21. PMID:12042196. |
one recent study reported an association of an allele of the taqi polymorphism located in the fifth intron of the gene for dopamine beta-hydroxylase (dbh). |
2002-06-21 |
2023-08-12 |
Not clear |
| Lidia Serova, Mark Rivkin, Akira Nakashima, Esther L Sabba. Estradiol stimulates gene expression of norepinephrine biosynthetic enzymes in rat locus coeruleus. Neuroendocrinology. vol 75. issue 3. 2002-05-03. PMID:11914591. |
dopamine beta-hydroxylase (dbh) mrna levels were also similarly increased. |
2002-05-03 |
2023-08-12 |
rat |
| Nektaria Markoglou, Irving W Waine. On-line synthesis utilizing immobilized enzyme reactors based upon immobilized dopamine beta-hydroxylase. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 766. issue 1. 2002-05-02. PMID:11820290. |
immobilized enzyme reactors (imers) based upon dopamine beta-hydroxylase (dbh) have been developed. |
2002-05-02 |
2023-08-12 |
Not clear |
| Hyemyung Seo, Seok Jong Hong, Su Guo, Hee-Sun Kim, Chun-Hyung Kim, Dong-Youn Hwang, Ole Isacson, Arnon Rosenthal, Kwang-Soo Ki. A direct role of the homeodomain proteins Phox2a/2b in noradrenaline neurotransmitter identity determination. Journal of neurochemistry. vol 80. issue 5. 2002-04-16. PMID:11948255. |
here, we show that phox2a directly controls the na identity by activating na-synthesizing dopamine beta-hydroxylase (dbh ) gene. |
2002-04-16 |
2023-08-12 |
zebrafish |
| Chun-Hyung Kim, Cyrus P Zabetian, Joseph F Cubells, Sonhae Cho, Italo Biaggioni, Bruce M Cohen, David Robertson, Kwang-Soo Ki. Mutations in the dopamine beta-hydroxylase gene are associated with human norepinephrine deficiency. American journal of medical genetics. vol 108. issue 2. 2002-04-03. PMID:11857564. |
norepinephrine (ne), a key neurotransmitter of the central and peripheral nervous systems, is synthesized by dopamine beta-hydroxylase (dbh) that catalyzes oxidation of dopamine (da) to ne. |
2002-04-03 |
2023-08-12 |
human |
| T Bungo, S I Kawakami, A Ohgushi, K Sashihara, N Saito, K Sugahara, S Hasegawa, D M Denbow, M Furus. Intracerebroventricular injection of fusaric acid attenuates the anorexia by glucagon-like peptide-1 in the neonatal chick. Pharmacology, biochemistry, and behavior. vol 70. issue 2-3. 2002-02-05. PMID:11701195. |
however, in spite of that dopamine (da) did not affect food intake, coadministration of inhibitor of dopamine-beta-hydroxylase (dbh), fusaric acid (fa), attenuated the suppressive effect of glp-1 on feeding behavior. |
2002-02-05 |
2023-08-12 |
rat |
| b' N Petrovi\\xc4\\x87, G Cviji\\xc4\\x87, V Davidovi\\xc4\\x8. The activity of antioxidant enzymes and the content of uncoupling protein-1 in the brown adipose tissue of hypothyroid rats: comparison with effects of iopanoic acid. Physiological research. vol 50. issue 3. 2002-01-25. PMID:11521740.' |
besides, the mitochondrial concentration of uncoupling protein-1 (ucp-1) and the activity of catecholamine degrading enzyme monoamine oxidase (mao) in the ibat as well as the activity of the catecholamine synthesizing enzyme, dopamine beta-hydroxylase (dbh) in rat serum were examined. |
2002-01-25 |
2023-08-12 |
rat |
| R Bournaud, J Hidalgo, H Yu, E Jaimovich, T Shimahar. Low threshold T-type calcium current in rat embryonic chromaffin cells. The Journal of physiology. vol 537. issue Pt 1. 2002-01-22. PMID:11711559. |
in cells cultured for 1-4 days, the embryonic chromaffin cells were immunohistochemically identified by using polyclonal antibodies against dopamine beta-hydroxylase (dbh) and syntaxin. |
2002-01-22 |
2023-08-12 |
rat |