| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Depondt, H R Cock, D G Healy, M W Burley, D Weinshenker, N W Wood, D B Goldstein, S M Sisodiy. The -1021C->T DBH gene variant is not associated with epilepsy or antiepileptic drug response. Neurology. vol 63. issue 8. 2006-01-18. PMID:15505174. |
dopamine beta-hydroxylase (dbh) catalyzes the conversion of dopamine to norepinephrine (ne). |
2006-01-18 |
2023-08-12 |
Not clear |
| Ling Tong, Richard A Altschuler, Avril Genene Hol. Tyrosine hydroxylase in rat auditory midbrain: distribution and changes following deafness. Hearing research. vol 206. issue 1-2. 2005-12-15. PMID:16080996. |
we also identified immunolabeling for fibers and puncta for another catecholaminergic enzyme, dopamine beta hydroxylase (dbh), but not phenylethanolamine-n-methyltranferase (pnmt). |
2005-12-15 |
2023-08-12 |
rat |
| Henrik Berg Rasmussen, Thomas Werg. Genotyping of the 19-bp insertion/deletion polymorphism in the 5' flank of beta-hydroxylase gene by dissociation analysis of allele-specific PCR products. Clinical chemistry and laboratory medicine. vol 43. issue 9. 2005-12-06. PMID:16176167. |
the 19-bp insertion/deletion polymorphism in the 5' flank of the dopamine beta-hydroxylase (dbh) gene has been associated with psychiatric disorders. |
2005-12-06 |
2023-08-12 |
Not clear |
| Marlene M Hsieh, George Lupas, Jennifer Rychlik, Suzan Dziennis, Beth A Habecker, Elaine J Lewi. ERK1/2 is a negative regulator of homeodomain protein Arix/Phox2a. Journal of neurochemistry. vol 94. issue 6. 2005-10-27. PMID:16156742. |
treatment of sympathetic neurons with the mek1 inhibitor, pd98059, results in an elevation of mrnas encoding noradrenergic proteins, dopamine beta-hydroxylase (dbh) and norepinephrine transporter (net), but not tyrosine hydroyxlase (th). |
2005-10-27 |
2023-08-12 |
Not clear |
| Jesse R Schank, L Cameron Liles, David Weinshenke. Reduced anticonvulsant efficacy of valproic acid in dopamine beta-hydroxylase knockout mice. Epilepsy research. vol 65. issue 1-2. 2005-10-19. PMID:15955669. |
to test this hypothesis, we measured flurothyl-induced seizure susceptibility and severity parameters after both acute and chronic vpa treatments in dopamine beta-hydroxylase knockout (dbh -/-) mice that lack ne. |
2005-10-19 |
2023-08-12 |
mouse |
| Meng-Yang Zhu, Wei-Ping Wang, Abiye H Iyo, Gregory A Ordway, Kwang-Soo Ki. Age-associated changes in mRNA levels of Phox2, norepinephrine transporter and dopamine beta-hydroxylase in the locus coeruleus and adrenal glands of rats. Journal of neurochemistry. vol 94. issue 3. 2005-09-19. PMID:16033425. |
age-related changes in the gene expression of the transcription factors, phox2a and 2b, and two marker proteins, norepinephrine transporter (net) and dopamine beta-hydroxylase (dbh), of noradrenergic neurons were characterized in the locus coeruleus (lc) and adrenal glands using in situ hybridization. |
2005-09-19 |
2023-08-12 |
rat |
| Michiko Abe, Zhihong Wu, Miyuki Yamamoto, Jing Ji Jin, Yasuharu Tabara, Masaki Mogi, Katsuhiko Kohara, Tetsuro Miki, Jun Nakur. Association of dopamine beta-hydroxylase polymorphism with hypertension through interaction with fasting plasma glucose in Japanese. Hypertension research : official journal of the Japanese Society of Hypertension. vol 28. issue 3. 2005-09-06. PMID:16097364. |
dopamine-beta-hydroxylase (dbh) catalyzes the conversion of dopamine to norepinephrine and is released from sympathetic neurons into the circulation. |
2005-09-06 |
2023-08-12 |
Not clear |
| Melissa D Marino, Brooke N Bourdélat-Parks, L Cameron Liles, David Weinshenke. Genetic reduction of noradrenergic function alters social memory and reduces aggression in mice. Behavioural brain research. vol 161. issue 2. 2005-08-02. PMID:15922045. |
we tested dopamine beta-hydroxylase knockout (dbh -/-) mice that lack na in various social behavior paradigms. |
2005-08-02 |
2023-08-12 |
mouse |
| Raja Parasuraman, Pamela M Greenwood, Reshma Kumar, John Fossell. Beyond heritability: neurotransmitter genes differentially modulate visuospatial attention and working memory. Psychological science. vol 16. issue 3. 2005-07-21. PMID:15733200. |
in a second experiment, 103 healthy persons were genotyped for a g-to-a polymorphism of the dopamine beta-hydroxylase (dbh) gene. |
2005-07-21 |
2023-08-12 |
Not clear |
| J Iqbal, T R Manley, Q Yue, M R Namavar, I J Clark. Noradrenergic regulation of hypothalamic cells that produce growth hormone-releasing hormone and somatostatin and the effect of altered adiposity in sheep. Journal of neuroendocrinology. vol 17. issue 6. 2005-07-21. PMID:15929740. |
we also studied the effects of altered body weight on expression of dopamine beta-hydroxylase (dbh), the enzyme that produces noradrenalin from dopamine. |
2005-07-21 |
2023-08-12 |
Not clear |
| Philip Seeman, David Weinshenker, Remi Quirion, Lalit K Srivastava, Sanjeev K Bhardwaj, David K Grandy, Richard T Premont, Tatyana D Sotnikova, Patricia Boksa, Mufida El-Ghundi, Brian F O'dowd, Susan R George, Melissa L Perreault, Pekka T Männistö, Siobhan Robinson, Richard D Palmiter, Teresa Talleric. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 9. 2005-04-13. PMID:15716360. |
dopamine supersensitivity occurs in schizophrenia and other psychoses, and after hippocampal lesions, antipsychotics, ethanol, amphetamine, phencyclidine, gene knockouts of dbh (dopamine beta-hydroxylase), drd4 receptors, gprk6 (g protein-coupled receptor kinase 6), comt (catechol-o-methyltransferase), or th-/-, dbhth/+ (tyrosine hydroxylase), and in rats born by cesarean-section. |
2005-04-13 |
2023-08-12 |
rat |
| Becky Inkster, Pierandrea Muglia, Umesh Jain, James L Kenned. Linkage disequilibrium analysis of the dopamine beta-hydroxylase gene in persistent attention deficit hyperactivity disorder. Psychiatric genetics. vol 14. issue 2. 2005-03-24. PMID:15167700. |
there are currently three studies (daly et al., 1999; roman et al., 2002; wigg et al., 2002) that have found an association between the dopamine beta-hydroxylase gene (dbh) taqi 2 allele and childhood adhd. |
2005-03-24 |
2023-08-12 |
Not clear |
| Vera van Limpt, Alexander Schramm, Arjan van Lakeman, Peter Sluis, Alvin Chan, Max van Noesel, Frank Baas, Huib Caron, Angelika Eggert, Rogier Verstee. The Phox2B homeobox gene is mutated in sporadic neuroblastomas. Oncogene. vol 23. issue 57. 2005-03-09. PMID:15516980. |
targets of phox2b are, for example, genes of the (nor)adrenalin synthesis route, like dopamine beta hydroxylase (dbh). |
2005-03-09 |
2023-08-12 |
Not clear |
| Franco Giubilei, Caterina Calderaro, Giovanni Antonini, Micaela Sepe-Monti, Paolo Tisei, Ercole Brunetti, Francesca Marchione, Brunella Caronti, Francesco E Pontier. Increased lymphocyte dopamine beta-hydroxylase immunoreactivity in Alzheimer's disease: compensatory response to cholinergic deficit? Dementia and geriatric cognitive disorders. vol 18. issue 3-4. 2005-02-16. PMID:15305112. |
here we show a slight decrease in acetylcholinesterase (ache) and a significant increase in dopamine beta-hydroxylase (dbh) immunoreactivity in the pbl of patients with probable alzheimer's disease (ad). |
2005-02-16 |
2023-08-12 |
Not clear |
| Natsuki Matsushita, Kenta Kobayashi, Jun-ichi Miyazaki, Kazuto Kobayash. Fate of transient catecholaminergic cell types revealed by site-specific recombination in transgenic mice. Journal of neuroscience research. vol 78. issue 1. 2005-02-07. PMID:15372500. |
we developed a cre-loxp-mediated recombination system under the control of the dopamine beta-hydroxylase (dbh) promoter, which drives gene expression in typical noradrenergic and adrenergic cell groups as well as in transient catecholaminergic cell types. |
2005-02-07 |
2023-08-12 |
mouse |
| Nancy K Mueller, Shi Di, Charles M Paden, James P Herma. Activity-dependent modulation of neurotransmitter innervation to vasopressin neurons of the supraoptic nucleus. Endocrinology. vol 146. issue 1. 2005-01-18. PMID:15388644. |
vesicular glutamate transporter 2, glutamic acid decarboxylase, and dopamine beta-hydroxylase (dbh) synaptic boutons were visualized in apposition to vasopressin neurons in the son. |
2005-01-18 |
2023-08-12 |
Not clear |
| Claire Matson Cannon, Luna Abdallah, Laurence H Tecott, Matthew J During, Richard D Palmite. Dysregulation of striatal dopamine signaling by amphetamine inhibits feeding by hungry mice. Neuron. vol 44. issue 3. 2005-01-18. PMID:15504330. |
by contrast, amph-induced hypophagia in response to the same dose of amph is not blunted in mice lacking the ability to make norepinephrine and epinephrine (dbh(-/-)), dopamine d(2) receptors (d2r(-/-)), dopamine d(1) receptors (d1r(-/-)), serotonin 2c receptors (htr2c(-/y)), neuropeptide y (npy(-/-)), and in mice with compromised melanocortin signaling (a(y)). |
2005-01-18 |
2023-08-12 |
mouse |
| J Deinum, A H van den Meiracker, F Boomsma, F J van Ittersum, R A Wevers, J W M Lender. [From gene to disease; dopamine-beta-hydroxylase deficiency and orthostatic hypotension]. Nederlands tijdschrift voor geneeskunde. vol 148. issue 36. 2004-11-09. PMID:15495941. |
the dbh gene encodes dopamine-beta-hydroxylase (dbetah), the enzyme that catalyses the formation of norepinephrine from dopamine. |
2004-11-09 |
2023-08-12 |
Not clear |
| Phillip C Usera, Simi Vincent, David Robertso. Human phenotypes and animal knockout models of genetic autonomic disorders. Journal of biomedical science. vol 11. issue 1. 2004-10-14. PMID:14730204. |
dopamine beta-hydroxylase (dbh), the norepinephrine transporter (net), and the vesicular monoamine transporter subtype 2 catalyze intracellular ne biosynthesis, ne reuptake from the synapse, and vesicular transport, respectively. |
2004-10-14 |
2023-08-12 |
mouse |
| Zenon Pidsudk. Distribution and chemical coding of neurons in intramural ganglia of the porcine urinary bladder trigone. Folia histochemica et cytobiologica. vol 42. issue 1. 2004-09-30. PMID:15046394. |
ten-microm-thick cryostat sections were processed for double-labelling immunofluorescence with antibodies against tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin (som), galanin (gal), vasoactive intestinal polypeptide (vip), nitric oxide synthase (nos), calcitonin gene-related peptide (cgrp), substance p (sp), leu5-enkephalin (lenk) and choline acetyltransferase (chat). |
2004-09-30 |
2023-08-12 |
Not clear |