| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J J Balcita-Pedicino, L Rinama. Noradrenergic axon terminals contact gastric preautonomic neurons in the paraventricular nucleus of the hypothalamus in rats. The Journal of comparative neurology. vol 501. issue 4. 2007-05-01. PMID:17278138. |
na varicosities were visualized by immunoperoxidase labeling of dopamine beta hydroxylase (dbh), and gastric preautonomic pvn neurons were identified by immunogold labeling of pseudorabies virus (prv) transported retrogradely and transneuronally from injection sites in the stomach wall. |
2007-05-01 |
2023-08-12 |
rat |
| Luc Jasmin, Mena Narasaiah, Duc Tie. Noradrenaline is necessary for the hedonic properties of addictive drugs. Vascular pharmacology. vol 45. issue 4. 2007-04-20. PMID:16899413. |
to determine whether noradrenaline (na) is an essential neurotransmitter for addictive and appetitive behaviors, we measured drug and food seeking in transgenic mice lacking dopamine beta-hydroxylase (dbh), the enzyme responsible for synthesizing na. |
2007-04-20 |
2023-08-12 |
mouse |
| C A Paladini, M J Beckstead, D Weinshenke. Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17156935. |
to determine how norepinephrine affects the basic physiological properties of catecholaminergic neurons, brain slices containing the substantia nigra pars compacta and locus coeruleus were studied with cell-attached and whole-cell recordings in control and dopamine beta-hydroxylase knockout (dbh -/-) mice that lack norepinephrine. |
2007-04-11 |
2023-08-12 |
mouse |
| C A Paladini, M J Beckstead, D Weinshenke. Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17156935. |
dopamine neurons recorded in the substantia nigra pars compacta similarly showed no differences between slices harvested from dbh -/- and control mice. |
2007-04-11 |
2023-08-12 |
mouse |
| Agnieszka Słopién, Monika Dmitrzak-Weglarz, Filip Rybakowski, Andrzej Rajewski, Joanna Hause. [Genetic background of ADHD: population studies, genes of the catecholamine system]. Psychiatria polska. vol 40. issue 1. 2007-03-20. PMID:16756025. |
according to other studies there is a relationship between polymorphism of dopamine transporter gene (dat), dopamine receptors genes: drd2, drd3, drd4, drd5, dopamine-beta-hydroxylase gene (dbh) and catechol-o-methyltransferase gene (comt) and adhd. |
2007-03-20 |
2023-08-12 |
Not clear |
| David S Goldstei. L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug. Cardiovascular drug reviews. vol 24. issue 3-4. 2007-03-13. PMID:17214596. |
l-dops is very effective in treatment of deficiency of dopamine-beta-hydroxylase (dbh), the enzyme required for conversion of dopamine to ne in sympathetic nerves. |
2007-03-13 |
2023-08-12 |
Not clear |
| Christopher P Smith, Sheena Sharma, Jena J Steinl. Age-related changes in sympathetic neurotransmission in rat retina and choroid. Experimental eye research. vol 84. issue 1. 2007-02-26. PMID:17074321. |
the purpose of this study was to ascertain whether dopamine beta-hydroxylase (dbh), beta1- and beta2-adrenergic receptor gene and protein expression are altered in the retina and choroid with age. |
2007-02-26 |
2023-08-12 |
rat |
| F Fernandez, R A Lea, N J Colson, C Bellis, S Quinlan, L R Griffith. Association between a 19 bp deletion polymorphism at the dopamine beta-hydroxylase (DBH) locus and migraine with aura. Journal of the neurological sciences. vol 251. issue 1-2. 2007-02-22. PMID:17095019. |
association between a 19 bp deletion polymorphism at the dopamine beta-hydroxylase (dbh) locus and migraine with aura. |
2007-02-22 |
2023-08-12 |
Not clear |
| F Fernandez, R A Lea, N J Colson, C Bellis, S Quinlan, L R Griffith. Association between a 19 bp deletion polymorphism at the dopamine beta-hydroxylase (DBH) locus and migraine with aura. Journal of the neurological sciences. vol 251. issue 1-2. 2007-02-22. PMID:17095019. |
our previous work has investigated dopamine related migraine candidate genes and has reported a significant allelic association with migraine of a microsatellite localised to the promoter region of the dopamine beta-hydroxylase (dbh) gene. |
2007-02-22 |
2023-08-12 |
Not clear |
| Marta Kopecková, Ivo Paclt, Petr Goet. Polymorphisms and low plasma activity of dopamine-beta-hydroxylase in ADHD children. Neuro endocrinology letters. vol 27. issue 6. 2007-02-15. PMID:17187001. |
dopamine-beta-hydroxylase (dbh) is an enzyme responsible for the conversion of dopamine into noradrenaline. |
2007-02-15 |
2023-08-12 |
human |
| Nipa Bhaduri, Kanchan Mukhopadhya. Lack of significant association between -1021C-->T polymorphism in the dopamine beta hydroxylase gene and attention deficit hyperactivity disorder. Neuroscience letters. vol 402. issue 1-2. 2007-01-16. PMID:16616989. |
dopamine beta hydroxylase (dbh) is the key enzyme which converts dopamine to ne and since dbh gene is considered a major quantitative trait locus for plasma dbh activity, genetic polymorphism may lead to altered ne neurotransmission. |
2007-01-16 |
2023-08-12 |
Not clear |
| M D Köhnke, W Kolb, A M Köhnke, U Lutz, S Schick, A Batr. DBH*444G/A polymorphism of the dopamine-beta-hydroxylase gene is associated with alcoholism but not with severe alcohol withdrawal symptoms. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 7. 2007-01-05. PMID:16252068. |
as the enzyme dopamine-beta-hydroxylase (dbetah) converts dopamine to norepinephrine and both transmitters seem to be involved in the pathology of alcoholism and severe alcohol withdrawal symptoms, the gene encoding dbetah (dbh) was applied to explore the genetic background of alcoholism and severe withdrawal symptoms. |
2007-01-05 |
2023-08-12 |
human |
| Mark A Bellgrove, Ziarih Hawi, Michael Gill, Ian H Robertso. The cognitive genetics of attention deficit hyperactivity disorder (ADHD): sustained attention as a candidate phenotype. Cortex; a journal devoted to the study of the nervous system and behavior. vol 42. issue 6. 2006-12-29. PMID:17131588. |
dbh encodes the enzyme that converts dopamine to noradrenaline and is crucial to catecholamine regulation. |
2006-12-29 |
2023-08-12 |
human |
| Mariola Grabowska, Małgorzata Schlegel-Zawadzka, Mariusz Papp, Gabriel Nowa. Effect of imipramine treatment on plasma dopamine beta-hydroxylase activity in chronic mild stress in rats. Polish journal of pharmacology. vol 56. issue 6. 2006-12-21. PMID:15662096. |
dopamine beta-hydroxylase (dbh) which catalyzes conversion of dopamine into noradrenaline, may be a good blood marker of unipolar depression. |
2006-12-21 |
2023-08-12 |
human |
| Yilang Tang, Sarah G Buxbaum, Irwin Waldman, George M Anderson, Cyrus P Zabetian, Michael D Köhnke, Joseph F Cubell. A single nucleotide polymorphism at DBH, possibly associated with attention-deficit/hyperactivity disorder, associates with lower plasma dopamine beta-hydroxylase activity and is in linkage disequilibrium with two putative functional single nucleotide polymorphisms. Biological psychiatry. vol 60. issue 10. 2006-12-20. PMID:16616730. |
a single nucleotide polymorphism at dbh, possibly associated with attention-deficit/hyperactivity disorder, associates with lower plasma dopamine beta-hydroxylase activity and is in linkage disequilibrium with two putative functional single nucleotide polymorphisms. |
2006-12-20 |
2023-08-12 |
Not clear |
| Yilang Tang, Sarah G Buxbaum, Irwin Waldman, George M Anderson, Cyrus P Zabetian, Michael D Köhnke, Joseph F Cubell. A single nucleotide polymorphism at DBH, possibly associated with attention-deficit/hyperactivity disorder, associates with lower plasma dopamine beta-hydroxylase activity and is in linkage disequilibrium with two putative functional single nucleotide polymorphisms. Biological psychiatry. vol 60. issue 10. 2006-12-20. PMID:16616730. |
the dbh gene regulates plasma dopamine beta-hydroxylase activity (pdbetah). |
2006-12-20 |
2023-08-12 |
Not clear |
| M J Drescher, D G Drescher, K M Khan, J S Hatfield, N A Ramakrishnan, M D Abu-Hamdan, L A Lemonnie. Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) are positioned to modulate afferent signaling in the cochlea. Neuroscience. vol 142. issue 1. 2006-12-20. PMID:16876955. |
we now demonstrate the existence of nerve fibers within the organ of corti which are immunoreactive for the adrenergic marker dopamine beta-hydroxylase (dbh). |
2006-12-20 |
2023-08-12 |
rat |
| Brooke N Bourdélat-Parks, George M Anderson, Zoe R Donaldson, Jay M Weiss, Robert W Bonsall, Milburn S Emery, L Cameron Liles, David Weinshenke. Effects of dopamine beta-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice. Psychopharmacology. vol 183. issue 1. 2006-12-12. PMID:16163519. |
dopamine beta-hydroxylase (dbh) converts dopamine (da) to norepinephrine (ne), thus playing a critical role in catecholamine metabolism. |
2006-12-12 |
2023-08-12 |
mouse |
| Takashi Moriguchi, Nakano Takako, Michito Hamada, Atsuko Maeda, Yuki Fujioka, Takashi Kuroha, Reuben E Huber, Susan L Hasegawa, Arvind Rao, Masayuki Yamamoto, Satoru Takahashi, Kim-Chew Lim, James Douglas Enge. Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation. Development (Cambridge, England). vol 133. issue 19. 2006-11-28. PMID:16943277. |
additionally, mrna analyses of purified chromaffin cells from gata3 mutants show that levels of mash1, hand2 and phox2b (postulated upstream regulators of gata3) as well as terminally differentiated sa lineage products (tyrosine hydroxylase, th, and dopamine beta-hydroxylase, dbh) are markedly altered. |
2006-11-28 |
2023-08-12 |
mouse |
| M S Hunsley, W R Curtis, R D Palmite. Behavioral and sleep/wake characteristics of mice lacking norepinephrine and hypocretin. Genes, brain, and behavior. vol 5. issue 6. 2006-11-01. PMID:16923149. |
mice with a targeted disruption of the dopamine beta-hydroxylase (dbh) gene (deficient in ne and epinephrine) or the hcrt gene were bred to generate double knockouts (dkos), each single ko (dbh-ko and hcrt-ko), and control mice. |
2006-11-01 |
2023-08-12 |
mouse |