| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elaine C Johnstone, Patricia L Yudkin, Kate Hey, Sarah J Roberts, Sarah J Welch, Michael F Murphy, Siân E Griffiths, Robert T Walto. Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch. Pharmacogenetics. vol 14. issue 2. 2004-09-30. PMID:15077009. |
polymorphisms in the dopamine d2 receptor (drd2 c/t and drd2 a/g) and in dopamine beta hydroxylase (dbh a/g) have been implicated in modulation of smoking and other reward-seeking behaviours. |
2004-09-30 |
2023-08-12 |
human |
| Mian Zhou, H Hank Simms, Ping Wan. Increased gut-derived norepinephrine release in sepsis: up-regulation of intestinal tyrosine hydroxylase. Biochimica et biophysica acta. vol 1689. issue 3. 2004-09-16. PMID:15276647. |
although the gut has been demonstrated to be the major source of ne in sepsis, it remains unknown whether the increased ne is associated with up-regulation of intestinal ne biosynthesis enzymes such as tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh). |
2004-09-16 |
2023-08-12 |
rat |
| P Szot, M Lester, M L Laughlin, R D Palmiter, L C Liles, D Weinshenke. The anticonvulsant and proconvulsant effects of alpha2-adrenoreceptor agonists are mediated by distinct populations of alpha2A-adrenoreceptors. Neuroscience. vol 126. issue 3. 2004-09-14. PMID:15183527. |
to determine whether the alpha2-ar agonists were acting on inhibitory presynaptic autoreceptors to decrease ne release or on postsynaptic receptors on ne target neurons, the effects of clonidine and guanfacine were determined in dopamine beta-hydroxylase knockout (dbh -/-) mice that lack ne. |
2004-09-14 |
2023-08-12 |
mouse |
| Raquel V Gallara, Salvador L Bellavia, Lidia L Serova, Esther L Sabba. Environmental light conditions alter gene expression of rat catecholamine biosynthetic enzymes and Neuropeptide Y: differential effect in superior cervical ganglia and adrenal gland. Brain research. Molecular brain research. vol 124. issue 2. 2004-08-26. PMID:15135223. |
the results of northern blot analysis show that ll exposure reduces mrna levels for tyrosine hydroxylase (th) the rate limiting catecholamine biosynthetic enzyme and also of dopamine beta-hydroxylase (dbh) as well as for npy in scg to about half the levels in control animals. |
2004-08-26 |
2023-08-12 |
rat |
| Esther L Sabban, Bistra B Nankova, Lidia I Serova, Richard Kvetnansky, Xiaoping Li. Molecular regulation of gene expression of catecholamine biosynthetic enzymes by stress: sympathetic ganglia versus adrenal medulla. Annals of the New York Academy of Sciences. vol 1018. 2004-08-18. PMID:15240392. |
stress induces tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) gene expression in sympathetic ganglia and adrenal medulla (am). |
2004-08-18 |
2023-08-12 |
rat |
| John F Cryan, Olivia F O'Leary, Sung-Ha Jin, Julie C Friedland, Ming Ouyang, Bradford R Hirsch, Michelle E Page, Ashutosh Dalvi, Steven A Thomas, Irwin Luck. Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 21. 2004-07-09. PMID:15148402. |
mice unable to synthesize norepinephrine (ne) and epinephrine due to targeted disruption of the dopamine beta-hydroxylase gene, dbh, were used to critically test roles for ne in mediating acute behavioral changes elicited by different classes of antidepressants. |
2004-07-09 |
2023-08-12 |
mouse |
| Matthias J T Kaiser, Gisa Tiegs, Winfried L Neuhube. Close apposition of dynorphin-positive nerve fibres to lymphocytes in the liver suggests opioidergic neuroimmunomodulation. Histochemistry and cell biology. vol 120. issue 3. 2004-06-10. PMID:12904970. |
antibodies directed against dynorphin a, met-enkephalin, endomorphin 1 and 2, mu, kappa- and delta-opioid receptors (mor, kor, dor), tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), cd4, cd8 and macrophages were used. |
2004-06-10 |
2023-08-12 |
mouse |
| Patrick Slama, Jean-Luc Boucher, Marius Réglie. Aromatic N-hydroxyguanidines as new reduction cosubstrates for dopamine beta-hydroxylase. Biochemical and biophysical research communications. vol 316. issue 4. 2004-05-21. PMID:15044095. |
conversion of neurotransmitter dopamine into norepinephrine is catalyzed by dopamine beta-hydroxylase (dbh). |
2004-05-21 |
2023-08-12 |
Not clear |
| J Deinum, G C H Steenbergen-Spanjers, M Jansen, F Boomsma, J W M Lenders, F J van Ittersum, N Hück, L P van den Heuvel, R A Wever. DBH gene variants that cause low plasma dopamine beta hydroxylase with or without a severe orthostatic syndrome. Journal of medical genetics. vol 41. issue 4. 2004-05-07. PMID:15060114. |
dbh gene variants that cause low plasma dopamine beta hydroxylase with or without a severe orthostatic syndrome. |
2004-05-07 |
2023-08-12 |
Not clear |
| Erik G Jönsson, Rami Abou Jamra, Johannes Schumacher, Lena Flyckt, Gunnar Edman, Kaj Forslund, Marja Mattila-Evenden, Gunnar Rylander, Marie Asberg, Lars Bjerkenstedt, Frits-Axel Wiesel, Peter Propping, Sven Cichon, Markus M Nöthen, Göran C Sedval. No association between a putative functional promoter variant in the dopamine beta-hydroxylase gene and schizophrenia. Psychiatric genetics. vol 13. issue 3. 2004-05-05. PMID:12960750. |
we attempted to investigate a putative functional promoter polymorphism in the dopamine beta-hydroxylase gene (dbh) for association with schizophrenia. |
2004-05-05 |
2023-08-12 |
Not clear |
| Daniel G Healy, Patrick M Abou-Sleiman, Tetsutaro Ozawa, Andrew J Lees, Kailash Bhatia, Kourosh R Ahmadi, Ullrich Wullner, Jose Berciano, J Carsten Moller, Christoph Kamm, Katrin Burk, Paolo Barone, Eduardo Tolosa, Niall Quinn, David B Goldstein, Nicholas W Wood, Paolo Barron. A functional polymorphism regulating dopamine beta-hydroxylase influences against Parkinson's disease. Annals of neurology. vol 55. issue 3. 2004-04-12. PMID:14991826. |
a functional --1021c --> t polymorphism in the dopamine beta-hydroxylase gene has been demonstrated to regulate plasma dbh activity. |
2004-04-12 |
2023-08-12 |
Not clear |
| Tessei Kuruma, Meiho Nakayama, Atushi Nakano, Men Dur Wu, Shigeru Inafuku, Guo Gang Fen. [Immunohistochemical study for monoamine neurons in the brain of unilateral inner ear impaired rats]. Nihon Jibiinkoka Gakkai kaiho. vol 106. issue 12. 2004-03-18. PMID:14733122. |
to visualize 5-hydroxytryptamine (5-ht), noradrenaline (na) and dopamine (da) neurons, we used mouse antibodies against 5-ht, na, and da syntheses, i.e., tryptophan hydroxylase (trh), tyrosine hydroxylase (th) and dopamine-beta-hydroxylase (dbh). |
2004-03-18 |
2023-08-12 |
mouse |
| Jennifer L Rychlik, Vincent Gerbasi, Elaine J Lewi. The interaction between dHAND and Arix at the dopamine beta-hydroxylase promoter region is independent of direct dHAND binding to DNA. The Journal of biological chemistry. vol 278. issue 49. 2004-03-10. PMID:14506227. |
dopamine beta-hydroxylase (dbh) catalyzes the production of norepinephrine, and its expression defines the noradrenergic phenotype. |
2004-03-10 |
2023-08-12 |
Not clear |
| Sonhae Cho, Chun-Hyung Kim, Joseph F Cubells, Cyrus P Zabetian, Dong-Youn Hwang, Jang-Woo Kim, Bruce M Cohen, Italo Biaggioni, David Robertson, Kwang-Soo Ki. Variations in the dopamine beta-hydroxylase gene are not associated with the autonomic disorders, pure autonomic failure, or multiple system atrophy. American journal of medical genetics. Part A. vol 120A. issue 2. 2004-02-20. PMID:12833405. |
recent findings of an association between human ne deficiency and variants at the dopamine beta-hydroxylase (dbh) gene [kim et al., 2002] prompted us to investigate these markers in patients with autonomic disorders; 38 with orthostatic intolerance (oi), 26 with pure autonomic failure (paf), and 39 with multiple system atrophy (msa). |
2004-02-20 |
2023-08-12 |
human |
| Steven J Swoap, David Weinshenker, Richard D Palmiter, Graham Garbe. Dbh(-/-) mice are hypotensive, have altered circadian rhythms, and have abnormal responses to dieting and stress. American journal of physiology. Regulatory, integrative and comparative physiology. vol 286. issue 1. 2004-02-10. PMID:12969876. |
we used mice deficient in dopamine beta-hydroxylase [dbh(-/-)] and their littermate controls [dbh(+/-)] to examine the role of epinephrine (epi) and norepinephrine (ne) in the maintenance of cardiovascular parameters during 7 days of caloric restriction and acute exposure to environmental stress. |
2004-02-10 |
2023-08-12 |
mouse |
| Karen Müller Smith, Mark Daly, Mariellen Fischer, Constantin T Yiannoutsos, Lorri Bauer, Russell Barkley, Bradford A Navi. Association of the dopamine beta hydroxylase gene with attention deficit hyperactivity disorder: genetic analysis of the Milwaukee longitudinal study. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 119B. issue 1. 2004-02-06. PMID:12707943. |
from this cohort, genetic analysis was performed in 105 caucasian subjects with adhd and 68 age and ethnicity-matched controls for the drd4 exon 3 vntr, the slc6a3 (dat1) 3' utr vntr, dopamine beta hydroxylase (dbh) taqi a polymorphism, and the dbh gt microsatellite repeat polymorphism that has been quantitatively associated with serum levels of dbh activity, but not previously studied in adhd. |
2004-02-06 |
2023-08-12 |
human |
| Krzysztof Wasowic. Changes in the expression of tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH), galanin (GAL), vasoactive intestinal polypeptide (VIP) and substance P (SP) in the uterine cervix-projecting neurons located in the lumbar paravertebral ganglia of the pig. Folia morphologica. vol 62. issue 3. 2004-01-22. PMID:14507051. |
changes in the expression of tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), galanin (gal), vasoactive intestinal polypeptide (vip) and substance p (sp) in the uterine cervix-projecting neurons located in the lumbar paravertebral ganglia of the pig. |
2004-01-22 |
2023-08-12 |
Not clear |
| Linda Rinama. Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 31. 2003-12-02. PMID:14602823. |
in the present study, noradrenergic (na) neurons [i.e., those that express the na synthetic enzyme dopamine beta hydroxylase (dbh)] in the caudal nst were lesioned to determine their role in mediating anorexic responses to gastric stimulation and in conveying gastric sensory signals to the hypothalamus and amygdala. |
2003-12-02 |
2023-08-12 |
human |
| Kenji Yamamoto, Joseph F Cubells, Joel Gelernter, Chawki Benkelfat, Pierre Lalonde, David Bloom, Samarthji Lal, Alain Labelle, Gustavo Turecki, Guy A Rouleau, Ridha Joobe. Dopamine beta-hydroxylase (DBH) gene and schizophrenia phenotypic variability: a genetic association study. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 117B. issue 1. 2003-11-06. PMID:12555232. |
dopamine beta-hydroxylase (dbh) gene and schizophrenia phenotypic variability: a genetic association study. |
2003-11-06 |
2023-08-12 |
human |
| Kenji Yamamoto, Joseph F Cubells, Joel Gelernter, Chawki Benkelfat, Pierre Lalonde, David Bloom, Samarthji Lal, Alain Labelle, Gustavo Turecki, Guy A Rouleau, Ridha Joobe. Dopamine beta-hydroxylase (DBH) gene and schizophrenia phenotypic variability: a genetic association study. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 117B. issue 1. 2003-11-06. PMID:12555232. |
recently, two polymorphisms (dbh5'-ins/del and dbh 444 g/a) of the dopamine beta hydroxylase (dbh) gene were isolated, and one haplotype (del-a) was found to be associated with low dbh activity and cocaine-induced paranoia. |
2003-11-06 |
2023-08-12 |
human |