| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| LinLin Tian, Morvarid Karimi, Susan K Loftin, Chris A Brown, HuChuan Xia, JinBin Xu, Robert H Mach, Joel S Perlmutte. No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease. PloS one. vol 7. issue 2. 2012-08-03. PMID:22359591. |
no differential regulation of dopamine transporter (dat) and vesicular monoamine transporter 2 (vmat2) binding in a primate model of parkinson disease. |
2012-08-03 |
2023-08-12 |
monkey |
| LinLin Tian, Morvarid Karimi, Susan K Loftin, Chris A Brown, HuChuan Xia, JinBin Xu, Robert H Mach, Joel S Perlmutte. No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease. PloS one. vol 7. issue 2. 2012-08-03. PMID:22359591. |
radioligands for dat and vmat2 are widely used presynaptic markers for assessing dopamine (da) nerve terminals in parkinson disease (pd). |
2012-08-03 |
2023-08-12 |
monkey |
| Shankar Sadasivan, Brooks B Pond, Amar K Pani, Chunxu Qu, Yun Jiao, Richard J Smeyn. Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice. PloS one. vol 7. issue 3. 2012-08-03. PMID:22470460. |
methylphenidate (mph) is a psychostimulant that exerts its pharmacological effects via preferential blockade of the dopamine transporter (dat) and the norepinephrine transporter (net), resulting in increased monoamine levels in the synapse. |
2012-08-03 |
2023-08-12 |
mouse |
| Monica L Andersen, Eileen K Sawyer, F Ivy Carroll, Leonard L Howel. Influence of chronic dopamine transporter inhibition by RTI-336 on motor behavior, sleep, and hormone levels in rhesus monkeys. Experimental and clinical psychopharmacology. vol 20. issue 2. 2012-08-01. PMID:22023668. |
dopamine transporter (dat) inhibitors have been developed as a promising treatment approach for cocaine dependence. |
2012-08-01 |
2023-08-12 |
human |
| Monica L Andersen, Eileen K Sawyer, F Ivy Carroll, Leonard L Howel. Influence of chronic dopamine transporter inhibition by RTI-336 on motor behavior, sleep, and hormone levels in rhesus monkeys. Experimental and clinical psychopharmacology. vol 20. issue 2. 2012-08-01. PMID:22023668. |
however, the stimulant effects of dat inhibitors have the potential to disrupt sleep patterns, and the influence of long-term treatment on dopamine neurochemistry is still unknown. |
2012-08-01 |
2023-08-12 |
human |
| b' Valentina Di Liberto, Johanna M\\xc3\\xa4kel\\xc3\\xa4, Laura Korhonen, Melania Olivieri, Timofey Tselykh, Annika M\\xc3\\xa4lki\\xc3\\xa4, Hai Do Thi, Natale Belluardo, Dan Lindholm, Giuseppa Mud\\xc3\\xb. Involvement of estrogen receptors in the resveratrol-mediated increase in dopamine transporter in human dopaminergic neurons and in striatum of female mice. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22041555.' |
here we studied the role of rsv in the regulation of dopamine transporter (dat) in the striatum using male and female mice. |
2012-07-27 |
2023-08-12 |
mouse |
| Christian Sommerauer, Patrick Rebernik, Harald Reither, Christian Nanoff, Christian Pif. The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22155208. |
in order to re-examine its action at human variants of these proteins on intact cells we established cells stably expressing the human nr1/2a nmda-receptor, noradrenaline transporter (nat) or dopamine transporter (dat) and tested the activity of amantadine in patch-clamp, uptake, release, and cytotoxicity experiments. |
2012-07-27 |
2023-08-12 |
human |
| Chin-Bin Yeh, Yuan-Hwa Chou, Cheng-Yi Cheng, Meei-Shyuan Lee, Jhi-Joung Wang, Chiang-Hsuan Lee, Chyng-Yann Shiue, Tung-Ping Su, Wen-Sheng Huan. Reproducibility of brain dopamine transporter binding with Tc-99m TRODAT-1 SPECT in healthy young men. Psychiatry research. vol 201. issue 3. 2012-07-24. PMID:22551783. |
single photon emission computed tomography (spect) with tc-99m trodat-1 as ligand can be used to evaluate striatal dopamine transporters (dat) in young subjects. |
2012-07-24 |
2023-08-12 |
human |
| Arianna Bellucci, Laura Navarria, Elisa Falarti, Michela Zaltieri, Federica Bono, Ginetta Collo, Maria Grazia Spillantini, Maria Grazia, Cristina Missale, Pierfranco Span. Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease. PloS one. vol 6. issue 12. 2012-07-20. PMID:22163275. |
in particular, α-synuclein may affect dopaminergic neuron function as it interacts with a key protein modulating dopamine (da) content at the synapse: the da transporter (dat). |
2012-07-20 |
2023-08-12 |
mouse |
| A M Smith, K A Wellmann, T M Lundblad, M L Carter, S Barron, L P Dwoski. Lobeline attenuates neonatal ethanol-mediated changes in hyperactivity and dopamine transporter function in the prefrontal cortex in rats. Neuroscience. vol 206. 2012-07-18. PMID:22119644. |
in the current study, lobeline, which interacts with proteins in dopaminergic presynaptic terminals, was evaluated for its ability to attenuate neonatal ethanol-induced locomotor hyperactivity and alterations in dopamine transporter (dat) function in striatum and prefrontal cortex (pfc). |
2012-07-18 |
2023-08-12 |
rat |
| Ruth Tellez, Leticia Gómez-Víquez, Alfredo Menese. GABA, glutamate, dopamine and serotonin transporters expression on memory formation and amnesia. Neurobiology of learning and memory. vol 97. issue 2. 2012-07-05. PMID:22183017. |
notwithstanding several neurotransmission systems are frequently related to memory formation, amnesia and/or therapeutic targets for memory alterations, the role of transporters γ-aminobutyric acid (gaba, gat1), glutamate (neuronal glutamate transporter excitatory amino acid carrier; eacc1), dopamine (dat) and serotonin (sert) is poorly understood. |
2012-07-05 |
2023-08-12 |
rat |
| A Varrone, C Halldi. New developments of dopaminergic imaging in Parkinson's disease. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 56. issue 1. 2012-07-05. PMID:22460161. |
single photon emission tomography (spect) has played an important role as main molecular imaging modality because of the availability of imaging tools such as dopamine transporter (dat) radioligands for wide clinical use. |
2012-07-05 |
2023-08-12 |
Not clear |
| Ka Kit Wong, Martijn L T M Müller, Hiroto Kuwabara, Stephanie A Studenski, Nicolaas I Bohne. Gender differences in nigrostriatal dopaminergic innervation are present at young-to-middle but not at older age in normal adults. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 19. issue 1. 2012-07-03. PMID:22030267. |
we performed an evaluation for gender effects on striatal dopamine transporter (dat) binding in a group of normal subjects. |
2012-07-03 |
2023-08-12 |
human |
| Ikuo Odano, Andrea Varrone, Ivanka Savic, Carolina Ciumas, Per Karlsson, Aurelija Jucaite, Christer Halldin, Lars Fard. Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter--application to juvenile myoclonic epilepsy. NeuroImage. vol 59. issue 4. 2012-07-03. PMID:22056530. |
the dopamine transporter (dat) is of central interest in research on the pathophysiology and treatment of neuro-psychiatric disorders. |
2012-07-03 |
2023-08-12 |
human |
| Andrea Varrone, Balázs Gulyás, Akihiro Takano, Michael G Stabin, Cathrine Jonsson, Christer Halldi. Simplified quantification and whole-body distribution of [18F]FE-PE2I in nonhuman primates: prediction for human studies. Nuclear medicine and biology. vol 39. issue 2. 2012-06-29. PMID:22033024. |
[(18)f]fe-pe2i is a promising dopamine transporter (dat) radioligand. |
2012-06-29 |
2023-08-12 |
human |
| Wadad Saba, Marie-Anne Peyronneau, Frédéric Dollé, Sébastien Goutal, Michel Bottlaender, Héric Valett. Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling Part I: PET studies. Nuclear medicine and biology. vol 39. issue 2. 2012-06-29. PMID:22033025. |
lbt-999 (e)-n-(4-fluorobut-2-enyl)-2β-carbomethoxy-3β-(4'-tolyl)nortropane is a dopamine transporter (dat) ligand. |
2012-06-29 |
2023-08-12 |
Not clear |
| Anjali Rao, Toni L Richards, Diana Simmons, Nancy R Zahniser, Alexander Sorki. Epitope-tagged dopamine transporter knock-in mice reveal rapid endocytic trafficking and filopodia targeting of the transporter in dopaminergic axons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 5. 2012-06-29. PMID:22267337. |
the plasma membrane dopamine (da) transporter (dat) is essential for reuptake of extracellular da. |
2012-06-29 |
2023-08-12 |
mouse |
| Floriana Volpicelli, Roberto De Gregorio, Salvatore Pulcrano, Carla Perrone-Capano, Umberto di Porzio, Gian Carlo Bellench. Direct regulation of Pitx3 expression by Nurr1 in culture and in developing mouse midbrain. PloS one. vol 7. issue 2. 2012-06-29. PMID:22363463. |
during development the expression of nurr1 precedes that of pitx3 and those of typical dopaminergic markers such as tyrosine hydroxylase (th) and dopamine transporter (dat) that are directly regulated by nurr1. |
2012-06-29 |
2023-08-12 |
mouse |
| Vesna Sossi, Katherine Dinelle, Salma Jivan, Kristina Fischer, James E Holden, Doris Doude. In vivo dopamine transporter imaging in a unilateral 6-hydroxydopamine rat model of Parkinson disease using 11C-methylphenidate PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 53. issue 5. 2012-06-25. PMID:22492730. |
dopamine transporter (dat) function is altered by many neurodegenerative diseases. |
2012-06-25 |
2023-08-12 |
rat |
| Stephanie M Groman, Buyean Lee, Emanuele Seu, Alex S James, Karen Feiler, Mark A Mandelkern, Edythe D London, J David Jentsc. Dysregulation of D₂-mediated dopamine transmission in monkeys after chronic escalating methamphetamine exposure. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 17. 2012-06-25. PMID:22539846. |
dopamine d₂-like receptor and dopamine transporter (dat) availability and reversal-learning performance were measured before and after exposure to methamphetamine (or saline), and brain dopamine levels were assayed at the conclusion of the study. |
2012-06-25 |
2023-08-12 |
monkey |