| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I E M de Jong, P J Steenbergen, E R de Kloe. Strain differences in the effects of adrenalectomy on the midbrain dopamine system: implication for behavioral sensitization to cocaine. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18420350. |
for that purpose, we have measured tyrosine hydroxylase (th) and dopamine transporter (dat) mrna and d1- and d2-like receptor binding in c57bl/6 and dba/2 mice that were i) unoperated, ii) adx or sham (sham) operated, or iii) adx or sham operated and subjected to a cocaine sensitization regimen (15.0 mg/kg cocaine on nine consecutive days, followed by a 7.5 mg/kg challenge after a 5-day withdrawal). |
2009-06-08 |
2023-08-12 |
mouse |
| Y-M Tian, X Chen, D-Z Luo, X-H Zhang, H Xue, L-F Zheng, N Yang, X-M Wang, J-X Zh. Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18420351. |
immunofluorescence, reverse transcription (rt)-real time polymerase chain reaction (pcr) and western blot were used to evaluate and compare the levels of mrna and protein expression of tyrosine hydroxylase (th) and dopamine transporter (dat) in the gi tract between normal and rodent pd models, as well as between 6-ohda-treated rats and mptp-treated mice. |
2009-06-08 |
2023-08-12 |
mouse |
| Takeshi Tsuji, Masato Asanuma, Ikuko Miyazaki, Ko Miyoshi, Norio Ogaw. Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen. Neurochemical research. vol 34. issue 4. 2009-06-03. PMID:18946735. |
the reduction of dopamine transporter (dat)-positive signals and ppar gamma expression, and accumulation of activated microglial cells were significantly and dose-dependently attenuated by four injections of a nonsteroidal anti-inflammatory drug and a ppar gamma ligand, ibuprofen (10 or 20 mg/kg x 4, s.c.) given 30 min prior to each meth injection, but not by either a low or high dose of aspirin. |
2009-06-03 |
2023-08-12 |
Not clear |
| Lane J Wallace, Rachel M Hughe. Computational analysis of stimulated dopaminergic synapses suggests release largely occurs from a single pool of vesicles. Synapse (New York, N.Y.). vol 62. issue 12. 2009-05-26. PMID:18792991. |
in addition, these experiments have suggested that cocaine and other dopamine transporter (dat) inhibitors promote transfer of vesicles or dopamine itself from a reserve pool to a readily available pool. |
2009-05-26 |
2023-08-12 |
Not clear |
| Tomokazu Amano, Theodora Papanikolaou, Li-Ying Sung, Jessica Lennington, Joanne Conover, Xiangzhong Yan. Nuclear transfer embryonic stem cells provide an in vitro culture model for Parkinson's disease. Cloning and stem cells. vol 11. issue 1. 2009-05-26. PMID:19196042. |
in vitro differentiation of aphakia escs to dopaminergic neurons revealed significantly fewer th+ neurons that expressed map2, dat, synaptophysin, vmat2, and ahd2 compared to control nuclear transfer esc cultures, supporting a role for pitx3 in mesodiencephalic dopamine neuron maturation. |
2009-05-26 |
2023-08-12 |
mouse |
| Richard B Rothman, Christina M Dersch, Subramaniam Ananthan, John S Partill. Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release. The Journal of pharmacology and experimental therapeutics. vol 329. issue 2. 2009-05-22. PMID:19244097. |
recent studies identified novel allosteric modulators of the dopamine (da) transporter (dat). |
2009-05-22 |
2023-08-12 |
Not clear |
| Richard B Rothman, Christina M Dersch, Subramaniam Ananthan, John S Partill. Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release. The Journal of pharmacology and experimental therapeutics. vol 329. issue 2. 2009-05-22. PMID:19244097. |
n-(diphenylmethyl)-2-phenyl-4-quinazolinamine (sori-9804), n-(2,2-diphenylethyl)-2-phenyl-4-quinazolinamine (sori-20040), and n-(3,3-diphenylpropyl)-2-phenyl-4-quinazolinamine (sori-20041) partially inhibited [(125)i]3beta-(4'-iodophenyl)tropan-2beta-carboxylic acid methyl ester (rti-55) binding, slowed the dissociation rate of [(125)i]rti-55 from the dat, and partially inhibited [(3)h]dopamine uptake. |
2009-05-22 |
2023-08-12 |
Not clear |
| Oya Orun, S Rasmussen, U Gethe. Introducing tetraCys motifs at two different sites results in a functional dopamine transporter. Acta biologica Hungarica. vol 60. issue 1. 2009-05-14. PMID:19378920. |
we have introduced tetracysteine motifs into different positions of the dopamine transporter (dat) for specific flash labeling. |
2009-05-14 |
2023-08-12 |
Not clear |
| Tzung Lieh Yeh, I Hui Lee, Kao Ching Chen, Po See Chen, Wei Jen Yao, Yeng Kuang Yang, Nan Tsing Chiu, Ru Band L. The relationships between daily life events and the availabilities of serotonin transporters and dopamine transporters in healthy volunteers--a dual-isotope SPECT study. NeuroImage. vol 45. issue 2. 2009-05-13. PMID:19130891. |
the aim of this study was to examine the relationships between the daily life events and the availabilities of serotonin transporters (sert) and dopamine transporters (dat) in healthy volunteers. |
2009-05-13 |
2023-08-12 |
human |
| Swen Hesse, Olaf Ballaschke, Henryk Barthel, Osama Sabr. Dopamine transporter imaging in adult patients with attention-deficit/hyperactivity disorder. Psychiatry research. vol 171. issue 2. 2009-05-11. PMID:19176281. |
we used high-resolution brain-dedicated single-photon emission computed tomography and the dopamine transporter (dat) marker [(123)i]fp-cit in 17 adult treatment-naïve adhd patients and 14 age-matched controls. |
2009-05-11 |
2023-08-12 |
Not clear |
| Erik B Oleson, Sanjay Talluri, Steven R Childers, James E Smith, David C S Roberts, Keith D Bonin, Evgeny A Budygi. Dopamine uptake changes associated with cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 5. 2009-05-07. PMID:18923398. |
the data demonstrate that cocaine-induced dopamine transporter (dat) inhibition accounts for the accumbal dopamine fluctuations, which are associated with the cyclic regularity of cocaine intake observed during self-administration. |
2009-05-07 |
2023-08-12 |
rat |
| Erik B Oleson, Sanjay Talluri, Steven R Childers, James E Smith, David C S Roberts, Keith D Bonin, Evgeny A Budygi. Dopamine uptake changes associated with cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 5. 2009-05-07. PMID:18923398. |
although no significant change in the apparent k(m) was revealed in animals that exhibited an escalation in the rate of cocaine intake, an increased dopamine uptake rate was found suggesting an upregulation of dat number in response to a history of high cocaine intake. |
2009-05-07 |
2023-08-12 |
rat |
| Loreto A Egaña, Rolando A Cuevas, Tracy B Baust, Leonardo A Parra, Rehana K Leak, Sarah Hochendoner, Karina Peña, Marisol Quiroz, Weimin C Hong, Mario M Dorostkar, Roger Janz, Harald H Sitte, Gonzalo E Torre. Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 14. 2009-05-06. PMID:19357284. |
uptake through the dopamine transporter (dat) represents the primary mechanism used to terminate dopaminergic transmission in brain. |
2009-05-06 |
2023-08-12 |
mouse |
| Hong-xian Chen, Min-jie Ye, Ying Wang, Rui-ling Zhang, Wei Hao, Chang-qi L. [Dopamine D2 receptor and transportor [corrected] in the medial prefrontal contex of morphine-induced conditioned place preference in Sprague-Dawley rats]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 33. issue 9. 2009-04-28. PMID:18812656. |
to investigate the expression of dopamine d2 receptors (d2r) and dopamine transportors (dat) located in the medial prefrontal contex (mpfc) in high and low conditioned place preference (cpp) rats, and to unveil the possible mechanism leading to different cpp susceptibilities. |
2009-04-28 |
2023-08-12 |
rat |
| Gregory C Hadlock, Anthony J Baucum, Jill L King, Kristen A Horner, Glen A Cook, James W Gibb, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. Mechanisms underlying methamphetamine-induced dopamine transporter complex formation. The Journal of pharmacology and experimental therapeutics. vol 329. issue 1. 2009-04-28. PMID:19141713. |
in rats, this treatment also causes the formation of high-molecular mass (greater than approximately 120 kda) dopamine transporter (dat)-associated complexes, the loss of dat monomer immunoreactivity, and a decrease in dat function, as assessed in striatal synaptosomes prepared 24 h after meth treatment. |
2009-04-28 |
2023-08-12 |
rat |
| Jonathan Williams, Geir Sagvolden, Eric Taylor, Terje Sagvolde. Dynamic behavioural changes in the Spontaneously Hyperactive Rat: 1. Control by place, timing, and reinforcement rate. Behavioural brain research. vol 198. issue 2. 2009-04-22. PMID:18824036. |
the spontaneously hypertensive (hyperactive) rat has an abnormal dopamine transporter (dat), which is likely to be hypofunctional, thereby increasing the dopamine concentration and the learning rate. |
2009-04-22 |
2023-08-12 |
rat |
| Nicole L Bjorklund, Barbara A Sorg, James O Schen. Neuronal dopamine transporter activity, density and methamphetamine inhibition are differentially altered in the nucleus accumbens and striatum with no changes in glycosylation in rats behaviorally sensitized to methamphetamine. Synapse (New York, N.Y.). vol 62. issue 10. 2009-04-21. PMID:18651643. |
animals sensitized to methamphetamine (meth) have altered dopaminergic systems, including dopamine transporter (dat) activity. |
2009-04-21 |
2023-08-12 |
rat |
| Amy K Wagner, Laura L Drewencki, Xiangbai Chen, F Ryan Santos, Amina S Khan, Rashed Harun, Gonzalo E Torres, Adrian C Michael, C Edward Dixo. Chronic methylphenidate treatment enhances striatal dopamine neurotransmission after experimental traumatic brain injury. Journal of neurochemistry. vol 108. issue 4. 2009-04-20. PMID:19077052. |
dopamine (da) transporter (dat) localization, da-related proteins, and transcription factor (c-fos) expression were also assessed. |
2009-04-20 |
2023-08-12 |
rat |
| Nicolaas I Bohnen, Satyanarayana Gedela, Priyantha Herath, Gregory M Constantine, Robert Y Moor. Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity. Neuroscience letters. vol 447. issue 1. 2009-04-14. PMID:18838108. |
in this study we investigated the pathophysiology of hyposmia in pd using dopamine transporter (dat) pet. |
2009-04-14 |
2023-08-12 |
human |
| Nicolaas I Bohnen, Satyanarayana Gedela, Priyantha Herath, Gregory M Constantine, Robert Y Moor. Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity. Neuroscience letters. vol 447. issue 1. 2009-04-14. PMID:18838108. |
we conclude that selective hyposmia in pd is more robustly correlated with hippocampal rather than amygdala, ventral or dorsal striatal dopamine innervation as shown by dat binding. |
2009-04-14 |
2023-08-12 |
human |