| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ersin O Koylu, Burcu Balkan, Michael J Kuhar, Sakire Pogu. Cocaine and amphetamine regulated transcript (CART) and the stress response. Peptides. vol 27. issue 8. 2006-09-12. PMID:16822586. |
stress exposure modulates cart expression in hypothalamus and amygdala in rat brain in a region and sex specific manner. |
2006-09-12 |
2023-08-12 |
rat |
| Rebecca C Steiner, Hansen M Hsiung, Marina R Picciott. Cocaine self-administration and locomotor sensitization are not altered in CART knockout mice. Behavioural brain research. vol 171. issue 1. 2006-08-03. PMID:16621045. |
cocaine- and amphetamine-regulated transcript (cart) is a neuropeptide found throughout the brain, particularly in the nucleus accumbens (nacc) and hypothalamus. |
2006-08-03 |
2023-08-12 |
mouse |
| Jong Deok Ahn, Beatrice Dubern, Cecile Lubrano-Berthelier, Karine Clement, Gerard Karsent. Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency. Endocrinology. vol 147. issue 7. 2006-07-24. PMID:16614075. |
cart expression in the hypothalamus is increased in mice lacking melanocortin 4 receptor (mc4r(-/-) mice). |
2006-07-24 |
2023-08-12 |
mouse |
| Matthew P Parsons, Sa Li, Gilbert J Kiroua. The paraventricular nucleus of the thalamus as an interface between the orexin and CART peptides and the shell of the nucleus accumbens. Synapse (New York, N.Y.). vol 59. issue 8. 2006-06-16. PMID:16565962. |
the present anatomical experiments investigated the innervation of the pvt by fibers immunoreactive for orexin and cocaine and amphetamine related transcript (cart), two feeding-related peptides highly concentrated in the hypothalamus. |
2006-06-16 |
2023-08-12 |
Not clear |
| Audrey Guérardel, Mouna Barat-Houari, Francis Vasseur, Christian Dina, Vincent Vatin, Karine Clément, Delphine Eberlé, Valérie Vasseur-Delannoy, Christopher G Bell, Pilar Galan, Serge Hercberg, Nicole Helbecque, Natascha Potoczna, Fritz F Horber, Philippe Boutin, Philippe Frogue. Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population. BMC genetics. vol 6. 2006-05-24. PMID:15823203. |
cocaine and amphetamine regulated transcript (cart) is an anorectic neuropeptide located principally in hypothalamus. |
2006-05-24 |
2023-08-12 |
Not clear |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
the purpose of the present study was to investigate the effects of 2 weeks high fat feeding in wildtype mice on (1) insulin sensitivity and triglyceride accumulation in liver and muscle in relation to (2) mrna expression levels of neuropeptide y (npy), agouti-related protein (agrp), pro-opiomelanocortin (pomc), and cocaine- and amphetamine-regulated transcript (cart) in the hypothalamus. |
2006-02-28 |
2023-08-12 |
mouse |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
mrna expression levels of npy, agrp, pomc, and cart in the hypothalamus were not different between the groups. |
2006-02-28 |
2023-08-12 |
mouse |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
this study shows that 2 weeks of high fat feeding in mice does not affect mrna expression levels of npy, agrp, pomc or cart, in the whole hypothalamus, despite induction of hepatic, but not peripheral, insulin resistance. |
2006-02-28 |
2023-08-12 |
mouse |
| Tulin Yanik, Geraldina Dominguez, Michael J Kuhar, Emanuele M Del Giudice, Y Peng Lo. The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans. Endocrinology. vol 147. issue 1. 2006-02-03. PMID:16210370. |
cocaine- and amphetamine-regulated transcript (cart) is an anorexigenic neuropeptide synthesized in the hypothalamus. |
2006-02-03 |
2023-08-12 |
Not clear |
| Douglas Osei-Hyiaman, Michael Depetrillo, Judith Harvey-White, Anthony W Bannon, Benjamin F Cravatt, Michael J Kuhar, Ken Mackie, Miklós Palkovits, George Kuno. Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology. vol 81. issue 4. 2005-10-31. PMID:16131814. |
mice deficient in fatty acid amide hydrolase (faah), the enzyme responsible for the in vivo metabolism of the endocannabinoid anandamide, have reduced levels of cart-immunoreactive nerve fibers and terminals in several brain regions implicated in appetite control, including the arcuate, dorsomedial and periventricular nuclei of the hypothalamus, the amygdala, the bed nucleus of the stria terminalis and the nucleus accumbens, and treatment of faah(-/-) mice with rimonabant, 3 mg/kg/day for 7 days, increased cart levels toward those seen in faah(+/+) wild-type controls. |
2005-10-31 |
2023-08-12 |
mouse |
| Gavin A Bewick, Waljit S Dhillo, Sarah J Darch, Kevin G Murphy, James V Gardiner, Preeti H Jethwa, Wing May Kong, Mohammed A Ghatei, Stephen R Bloo. Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release. Endocrinology. vol 146. issue 8. 2005-09-26. PMID:15890775. |
double immunocytochemistry/in situ hybridization demonstrated that cart-ir and nop1 mrna are colocalized throughout the hypothalamus, in particular in the paraventricular nucleus, lateral hypothalamus, zona incerta, and arc, providing an anatomical basis for n/ofq action on cart release. |
2005-09-26 |
2023-08-12 |
rat |
| Kevin G Murph. Dissecting the role of cocaine- and amphetamine-regulated transcript (CART) in the control of appetite. Briefings in functional genomics & proteomics. vol 4. issue 2. 2005-09-23. PMID:16102267. |
cart is widely expressed in the central nervous system and the periphery, but is particularly concentrated in the hypothalamus. |
2005-09-23 |
2023-08-12 |
Not clear |
| Vani X Oliveira, Marcos A Fázio, M Terêsa M Miranda, Joelcimar M da Silva, Jackson C Bittencourt, Carol F Elias, Antonio Mirand. Leptin fragments induce Fos immunoreactivity in rat hypothalamus. Regulatory peptides. vol 127. issue 1-3. 2005-09-22. PMID:15680478. |
to investigate whether fos-ir was induced in the same neuronal group activated by leptin, we proceeded with a dual-label immunohistochemistry for cocaine- and amphetamine-regulated transcript (cart), a neuropeptide related to leptin action in rat hypothalamus. |
2005-09-22 |
2023-08-12 |
human |
| S-C Yang, K-R Shieh, H-Y L. Cocaine- and amphetamine-regulated transcript in the nucleus accumbens participates in the regulation of feeding behavior in rats. Neuroscience. vol 133. issue 3. 2005-09-07. PMID:15908130. |
furthermore, fasting suppressed cart mrna levels in the acbsh, paraventricular nucleus of the hypothalamus, arcuate nucleus, and the perifornical region, indicating that the acb is sensitive to fuel availability to an extent similar to those regions in the hypothalamus. |
2005-09-07 |
2023-08-12 |
rat |
| B S Mühlhäusler, C L Adam, E M Marrocco, P A Findlay, C T Roberts, J R McFarlane, K G Kauter, I C McMille. Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation. The Journal of physiology. vol 565. issue Pt 1. 2005-08-16. PMID:15661821. |
in the present study, our aim was to determine whether intrafetal glucose infusion increases fetal adiposity, synthesis and secretion of leptin and regulates gene expression of the 'appetite regulatory' neuropeptides neuropepetide y (npy), agouti-related peptide (agrp), pro-opiomelanocortin (pomc) and cocaine- and amphetamine-regulated transcript (cart) and receptors (leptin receptor (ob-rb) and melancortin 3 receptor (mc3r)) within the fetal hypothalamus. |
2005-08-16 |
2023-08-12 |
Not clear |
| B S Mühlhäusler, C L Adam, E M Marrocco, P A Findlay, C T Roberts, J R McFarlane, K G Kauter, I C McMille. Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation. The Journal of physiology. vol 565. issue Pt 1. 2005-08-16. PMID:15661821. |
glucose infusion increased mrna expression for pomc, but not for the anorectic neuropeptide cart, or the orexigenic neuropeptides npy and agrp, in the arcuate nucleus of the fetal hypothalamus. |
2005-08-16 |
2023-08-12 |
Not clear |
| De-Run Tian, Xiao-Dong Li, Yu-Shun Shi, You Wan, Xiao-Min Wang, Jaw-Kang Chang, Jun Yang, Ji-Sheng Ha. Changes of hypothalamic alpha-MSH and CART peptide expression in diet-induced obese rats. Peptides. vol 25. issue 12. 2005-06-07. PMID:15572204. |
compared to the dr rats and the control rats (fed with standard chow), dio rats were accompanied by a markedly higher energy intake and a decrease in the number of neurons carrying alpha-msh and cart peptide in the arcuate nucleus of the hypothalamus. |
2005-06-07 |
2023-08-12 |
rat |
| Aleksandra Vicentic, Anita Lakatos, Richard Hunter, Kelly Philpot, Geraldina Dominguez, Michael J Kuha. CART peptide diurnal rhythm in brain and effect of fasting. Brain research. vol 1032. issue 1-2. 2005-05-12. PMID:15680948. |
in the present study, we extend our observations by demonstrating that cart peptides also exhibit a diurnal rhythm in several brain regions, notably the nucleus accumbens, hypothalamus and amygdala, but not in the midbrain. |
2005-05-12 |
2023-08-12 |
Not clear |
| Csaba Fekete, Sumit Sarkar, Ronald M Lecha. Relative contribution of brainstem afferents to the cocaine- and amphetamine-regulated transcript (CART) innervation of thyrotropin-releasing hormone synthesizing neurons in the hypothalamic paraventricular nucleus (PVN). Brain research. vol 1032. issue 1-2. 2005-05-12. PMID:15680956. |
to determine the relative contribution of the brainstem to the cart innervation of the trh neurons in the pvn, the major ascending brainstem axonal pathways to the pvn were unilaterally transected in the hypothalamus. |
2005-05-12 |
2023-08-12 |
Not clear |
| Zhiyuan Hu, Seung Hun Cha, Goedelle van Haasteren, Jing Wang, M Daniel Lan. Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 11. 2005-05-09. PMID:15728730. |
the central administration of the fatty acid synthase (fas) inhibitor, c75, rapidly suppresses the expression of orexigenic neuropeptides [neuropeptide y (npy) and agouti-related protein (agrp)] and activates expression of anorexigenic neuropeptides [proopiomelanocortin (pomc) and cocaine- and amphetamine-regulated transcript (cart)] in the hypothalamus. |
2005-05-09 |
2023-08-12 |
Not clear |