| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Charnay, C Perrin, P G Vallet, B Greggio, E Kovari, C Boura. Mapping of cocaine and amphetamine regulated transcript (CART) mRNA expression in the hypothalamus of elderly human. Journal of chemical neuroanatomy. vol 17. issue 3. 2000-02-08. PMID:10609861. |
the expression of cocaine and amphetamine regulated transcript (cart) in the hypothalamus of aged humans was studied by in situ hybridization histochemistry. |
2000-02-08 |
2023-08-12 |
human |
| Y Charnay, C Perrin, P G Vallet, B Greggio, E Kovari, C Boura. Mapping of cocaine and amphetamine regulated transcript (CART) mRNA expression in the hypothalamus of elderly human. Journal of chemical neuroanatomy. vol 17. issue 3. 2000-02-08. PMID:10609861. |
formalin fixed coronal sections through the hypothalamus were hybridized with [35s]datp 3' end-labeled deoxyoligonucleotide probes complementary to sequences of the cart encoding gene. |
2000-02-08 |
2023-08-12 |
human |
| Y Charnay, C Perrin, P G Vallet, B Greggio, E Kovari, C Boura. Mapping of cocaine and amphetamine regulated transcript (CART) mRNA expression in the hypothalamus of elderly human. Journal of chemical neuroanatomy. vol 17. issue 3. 2000-02-08. PMID:10609861. |
large populations of cells expressing cart messenger rna were mainly detected in the paraventricular nucleus of the hypothalamus. |
2000-02-08 |
2023-08-12 |
human |
| Y Charnay, C Perrin, P G Vallet, B Greggio, E Kovari, C Boura. Mapping of cocaine and amphetamine regulated transcript (CART) mRNA expression in the hypothalamus of elderly human. Journal of chemical neuroanatomy. vol 17. issue 3. 2000-02-08. PMID:10609861. |
overall, the pattern of distribution of cart expressing cells observed throughout the human hypothalamus, with few exception, e.g. |
2000-02-08 |
2023-08-12 |
human |
| Z W Wang, Y T Zhou, T Kakuma, Y Lee, M Higa, S P Kalra, M G Dube, P S Kalra, R H Unge. Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 18. 1999-10-07. PMID:10468615. |
to determine whether the depletion of body fat caused by adenovirus-induced hyperleptinemia is mediated via the hypothalamus, we used as a "bioassay" for hypothalamic leptin activity the hypothalamic expression of a leptin-regulated peptide, cocaine- and amphetamine-regulated transcript (cart). |
1999-10-07 |
2023-08-12 |
rat |
| Z W Wang, Y T Zhou, T Kakuma, Y Lee, M Higa, S P Kalra, M G Dube, P S Kalra, R H Unge. Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 18. 1999-10-07. PMID:10468615. |
treatment of the high-fat-fed rats with adenovirus-leptin further increased their hyperleptinemia to 56 +/- 6 ng/ml without changing cart mrna or food intake, indicating that leptin action on hypothalamus had not been increased. |
1999-10-07 |
2023-08-12 |
rat |
| L Thim, P Kristensen, P F Nielsen, B S Wulff, J T Clause. Tissue-specific processing of cocaine- and amphetamine-regulated transcript peptides in the rat. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 6. 1999-05-20. PMID:10077578. |
in the present study we have purified cart peptides from extracts of adrenal gland, hypothalamus, nucleus accumbens, and pituitary gland (anterior and neurointermediate lobe) of the rat and determined the peptide structures by using microsequencing and mass spectrometry. |
1999-05-20 |
2023-08-12 |
rat |
| L Thim, P Kristensen, P F Nielsen, B S Wulff, J T Clause. Tissue-specific processing of cocaine- and amphetamine-regulated transcript peptides in the rat. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 6. 1999-05-20. PMID:10077578. |
from the adrenal gland, the cart(1-89) and cart(10-89) peptides were isolated, in contrast to the hypothalamus and nucleus accumbens, from which the shorter form peptides cart(42-89) and cart(49-89) were purified. |
1999-05-20 |
2023-08-12 |
rat |
| P B Jensen, P Kristensen, J T Clausen, M E Judge, S Hastrup, L Thim, B S Wulff, C Foged, J Jensen, J J Holst, O D Madse. The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans. FEBS letters. vol 447. issue 2-3. 1999-05-05. PMID:10214934. |
in the rat two alternatively spliced forms of cart mrna exist and quantitative pcr revealed expression of both forms in the hypothalamus, in the different islet tumors, and in the islets of langerhans. |
1999-05-05 |
2023-08-12 |
rat |
| S P Kalra, M G Dube, S Pu, B Xu, T L Horvath, P S Kalr. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocrine reviews. vol 20. issue 1. 1999-04-22. PMID:10047974. |
2) similarly, anorexigenic signal-producing pathways (e.g., crh, glp-1, alpha msh, and cart) orchestrate neural events for dissipation of appetite and to terminate feeding, possibly by interrupting npy efflux and action at a postsynaptic level within the hypothalamus. |
1999-04-22 |
2023-08-12 |
rat |
| P D Lambert, P R Couceyro, K M McGirr, S E Dall Vechia, Y Smith, M J Kuha. CART peptides in the central control of feeding and interactions with neuropeptide Y. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661247. |
also, in light microscopic immunohistochemical studies, npy-positive varicosities were observed around cart peptide-positive cell bodies in the paraventricular nucleus of the hypothalamus. |
1998-09-24 |
2023-08-12 |
rat |
| E O Koylu, P R Couceyro, P D Lambert, N C Ling, E B DeSouza, M J Kuha. Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland. Journal of neuroendocrinology. vol 9. issue 11. 1998-01-30. PMID:9419833. |
immunohistochemical localization of novel cart peptides in rat hypothalamus, pituitary and adrenal gland. |
1998-01-30 |
2023-08-12 |
rat |
| E O Koylu, P R Couceyro, P D Lambert, N C Ling, E B DeSouza, M J Kuha. Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland. Journal of neuroendocrinology. vol 9. issue 11. 1998-01-30. PMID:9419833. |
these findings indicate the presence of cart peptide(s) in the hypothalamus, pituitary, and adrenal gland. |
1998-01-30 |
2023-08-12 |
rat |