| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z A Archer, D V Rayner, J S Duncan, L M Bell, J G Merce. Introduction of a high-energy diet acutely up-regulates hypothalamic cocaine and amphetamine-regulated transcript, Mc4R and brown adipose tissue uncoupling protein-1 gene expression in male Sprague-Dawley rats. Journal of neuroendocrinology. vol 17. issue 1. 2005-04-28. PMID:15720470. |
ucp-1 mrna was elevated in interscapular brown adipose tissue from he-fed rats only at 12 h. cocaine and amphetamine-regulated transcript (cart) and mc4r gene expression in the hypothalamus were increased after 12 h and 24 h on an he diet, respectively. |
2005-04-28 |
2023-08-12 |
rat |
| Helga Davidowa, Yuzhen Li, Andreas Plageman. The main effect of cocaine- and amphetamine-regulated transcript (CART) peptide on hypothalamic neuronal activity depends on the nutritional state of rats. Neuro endocrinology letters. vol 26. issue 1. 2005-04-19. PMID:15726016. |
the anorectic and catabolic action of cart is primarily mediated by the hypothalamus. |
2005-04-19 |
2023-08-12 |
rat |
| Bogusława Baranowska, Ewa Wolińska-Witort, Lidia Martyńska, Magdalena Chmielowska, Agnieszka Baranowska-Bi. Effects of cocaine-amphetamine regulated transcript (CART) on hormone release. Regulatory peptides. vol 122. issue 2. 2005-04-08. PMID:15380921. |
cart is abundant in hypothalamus nuclei controlling anterior pituitary function. |
2005-04-08 |
2023-08-12 |
rat |
| Ling-Ling Hwang, Chiung-Tong Chen, Tzu-Ling Li, Chiung-Zuan Chiu, Shih-Fang Ch. Central pressor effects of CART peptides in anesthetized rats. Neuropeptides. vol 38. issue 2-3. 2004-08-30. PMID:15223268. |
the cart peptides were later found in the hypothalamus and functioned as anorectic peptides. |
2004-08-30 |
2023-08-12 |
rat |
| T A Rondini, S P Baddini, L F Sousa, J C Bittencourt, C F Elia. Hypothalamic cocaine- and amphetamine-regulated transcript neurons project to areas expressing gonadotropin releasing hormone immunoreactivity and to the anteroventral periventricular nucleus in male and female rats. Neuroscience. vol 125. issue 3. 2004-08-02. PMID:15099687. |
cocaine- and amphetamine-regulated transcript (cart) and cart-derived peptides are widely expressed in the hypothalamus. |
2004-08-02 |
2023-08-12 |
mouse |
| Si Ho Choi, Bum Sup Kwon, Seoul Lee, Thomas A Houpt, Hoon Taek Lee, Dong Goo Kim, Jeong Won Jahn. Systemic 5-hydroxy-L-tryptophan down-regulates the arcuate CART mRNA level in rats. Regulatory peptides. vol 115. issue 2. 2004-05-28. PMID:12972322. |
rats received intraperitoneal 5-hydroxy-l-tryptophan (5-htp; a single or three daily injections at a dose of 100 mg/kg/10 ml), and cart mrna level in the hypothalamus was examined by in situ hybridization at different time points. |
2004-05-28 |
2023-08-12 |
rat |
| Geneviève Beaudry, Hakima Zekki, Claude Rouillard, Daniel Lévesqu. Clozapine and dopamine D3 receptor antisense reduce cocaine- and amphetamine-regulated transcript expression in the rat nucleus accumbens shell. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696011. |
cocaine- and amphetamine-regulated transcript (cart) is a neuropeptide highly expressed in the hypothalamus and nucleus accumbens. |
2004-03-24 |
2023-08-12 |
rat |
| Csaba Fekete, Gábor Wittmann, Zsolt Liposits, Ronald M Lecha. Origin of cocaine- and amphetamine-regulated transcript (CART)-immunoreactive innervation of the hypothalamic paraventricular nucleus. The Journal of comparative neurology. vol 469. issue 3. 2004-03-15. PMID:14730586. |
we conclude that the cart innervation of the pvn derives from multiple neuronal sources of the hypothalamus and medulla. |
2004-03-15 |
2023-08-12 |
rat |
| Miklós Palkovit. Hypothalamic regulation of food intake. Ideggyogyaszati szemle. vol 56. issue 9-10. 2004-01-20. PMID:14608950. |
five groups of cells in the hypothalamus--arcuate, paraventricular, ventromedial and dorsomedial nuclei, and the dorsolateral hypothalamic area--contain neurons with either anorexic actions (alpha-msh, cart peptide, corticotropin-releasing hormone, urocortin iii, cholecystokinin, glucagon-like peptides) or that stimulate food intake (neuropeptide y, agouti-related peptide, orexins, melanin concentrating hormone, galanin). |
2004-01-20 |
2023-08-12 |
Not clear |
| Richard G Hunter, Michael J Kuha. CART peptides as targets for CNS drug development. Current drug targets. CNS and neurological disorders. vol 2. issue 3. 2003-08-27. PMID:12769800. |
the presence of cart immunoreactivity in specific nuclei of the hypothalamus has led to an examination of icv-injected cart peptides effects on feeding, which have proven to be significantly anorectic. |
2003-08-27 |
2023-08-12 |
human |
| Fabrice Bertile, Hugues Oudart, François Criscuolo, Yvon Le Maho, Thierry Raclo. Hypothalamic gene expression in long-term fasted rats: relationship with body fat. Biochemical and biophysical research communications. vol 303. issue 4. 2003-05-29. PMID:12684050. |
we have investigated whether and to what extent neuropeptide y (npy), agouti-related protein (agrp), melanin-concentrating hormone (mch), and prepro-orexin (prepro-ox) as well as pro-opiomelanocortin (pomc) and cocaine and amphetamine-regulated transcript (cart) mrna levels are affected in rat hypothalamus. |
2003-05-29 |
2023-08-12 |
rat |
| Niels Vrang, Philip J Larsen, Mads Tang-Christensen, Leif Kongskov Larsen, Peter Kristense. Hypothalamic cocaine-amphetamine regulated transcript (CART) is regulated by glucocorticoids. Brain research. vol 965. issue 1-2. 2003-05-01. PMID:12591118. |
cocaine-amphetamine-regulated transcript (cart) is one of the most abundantly expressed mrnas in the rat hypothalamus. |
2003-05-01 |
2023-08-12 |
rat |
| Huiyuan Zheng, Laurel M Patterson, Hans Rudolf Berthou. CART in the dorsal vagal complex: sources of immunoreactivity and effects on Fos expression and food intake. Brain research. vol 957. issue 2. 2003-02-25. PMID:12445972. |
based on retrograde tracing from the dvc combined with cart immunohistochemistry and supranodose vagotomy, we found that cart immunoreactivity in varicose fibers of the dorsal vagal complex originates from vagal afferents, sparse projections from the medullary reticular formation and the arcuate/retrochiasmatic nucleus of the hypothalamus, and most likely also from local cart neurons in the area postrema and nts. |
2003-02-25 |
2023-08-12 |
rat |
| Eriika Savontaus, Irene M Conwell, Sharon L Wardla. Effects of adrenalectomy on AGRP, POMC, NPY and CART gene expression in the basal hypothalamus of fed and fasted rats. Brain research. vol 958. issue 1. 2003-02-25. PMID:12468037. |
effects of adrenalectomy on agrp, pomc, npy and cart gene expression in the basal hypothalamus of fed and fasted rats. |
2003-02-25 |
2023-08-12 |
rat |
| Eriika Savontaus, Irene M Conwell, Sharon L Wardla. Effects of adrenalectomy on AGRP, POMC, NPY and CART gene expression in the basal hypothalamus of fed and fasted rats. Brain research. vol 958. issue 1. 2003-02-25. PMID:12468037. |
in order to understand the central mechanisms that mediate these effects of glucocorticoids we studied the effects of adrenalectomy (adx) and food deprivation on the expression of four neuropeptide genes (measured by s1 nuclease protection assay) in the medial basal hypothalamus (mbh), which are known to regulate energy balance: pro-opiomelanocortin (pomc), agouti-related peptide (agrp), neuropeptide y (npy), and cocaine and amphetamine regulated transcript (cart). |
2003-02-25 |
2023-08-12 |
rat |
| Miguel López, Luisa Seoane, Sulay Tovar, Rosa M Señarís, Carlos Diégue. Thyroid status regulates CART but not AgRP mRNA levels in the rat hypothalamus. Neuroreport. vol 13. issue 14. 2003-01-15. PMID:12395121. |
thyroid status regulates cart but not agrp mrna levels in the rat hypothalamus. |
2003-01-15 |
2023-08-12 |
rat |
| A Vaarmann, A Kas. Cocaine and amphetamine-regulated transcript peptide (CART(62-76))-induced changes in regional monoamine levels in ratbrain. Neuropeptides. vol 35. issue 5-6. 2002-11-25. PMID:12030814. |
in the hypothalamus, cart(62-76) increased the levels of 5-hiaa. |
2002-11-25 |
2023-08-12 |
rat |
| A J Robson, K Rousseau, A S I Loudon, F J P Eblin. Cocaine and amphetamine-regulated transcript mRNA regulation in the hypothalamus in lean and obese rodents. Journal of neuroendocrinology. vol 14. issue 9. 2002-10-23. PMID:12213131. |
cocaine and amphetamine-regulated transcript (cart) mrna and immunoreactivity are expressed abundantly in the hypothalamus. |
2002-10-23 |
2023-08-12 |
mouse |
| A J Robson, K Rousseau, A S I Loudon, F J P Eblin. Cocaine and amphetamine-regulated transcript mRNA regulation in the hypothalamus in lean and obese rodents. Journal of neuroendocrinology. vol 14. issue 9. 2002-10-23. PMID:12213131. |
cart mrna abundance in the arcuate nucleus of goldthioglucose-treated mice was decreased by 71% compared to levels in the control mice, but cart expression was unaffected in the dorsolateral hypothalamus. |
2002-10-23 |
2023-08-12 |
mouse |
| Niels Vrang, Philip J Larsen, Peter Kristense. Cocaine-amphetamine regulated transcript (CART) expression is not regulated by amphetamine. Neuroreport. vol 13. issue 9. 2002-09-10. PMID:12151772. |
cocaine-amphetamine-regulated transcript (cart) is one of the most abundantly expressed mrnas in the rat hypothalamus. |
2002-09-10 |
2023-08-12 |
rat |