| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Niels Vrang, Philip J Larsen, Peter Kristense. Cocaine-amphetamine regulated transcript (CART) expression is not regulated by amphetamine. Neuroreport. vol 13. issue 9. 2002-09-10. PMID:12151772. |
in the hypothalamus, cart mrna expression has been shown to be regulated by leptin, and cart peptides have been implicated in feeding behavior and in the regulation of the hpa-axis. |
2002-09-10 |
2023-08-12 |
rat |
| Niels Vrang, Philip J Larsen, Peter Kristense. Cocaine-amphetamine regulated transcript (CART) expression is not regulated by amphetamine. Neuroreport. vol 13. issue 9. 2002-09-10. PMID:12151772. |
in the present experiments we have re-examined the effects of amphetamine on cart expression in the forebrain and in the hypothalamus by the use of in situ hybridization. |
2002-09-10 |
2023-08-12 |
rat |
| Niels Vrang, Philip J Larsen, Peter Kristense. Cocaine-amphetamine regulated transcript (CART) expression is not regulated by amphetamine. Neuroreport. vol 13. issue 9. 2002-09-10. PMID:12151772. |
although we used the same amphetamine treatment paradigm as that originally reported we failed to demonstrate any regulation of cart mrna levels by amphetamine in either the forebrain or in the hypothalamus. |
2002-09-10 |
2023-08-12 |
rat |
| Hui-Yun Li, Hui-Wen Hwang, Yin-Hui H. Functional characterizations of cocaine- and amphetamine-regulated transcript mRNA expression in rat hypothalamus. Neuroscience letters. vol 323. issue 3. 2002-06-25. PMID:11959420. |
cart mrna was found in various regions in rat hypothalamus, including the periventricular nucleus, paraventricular nucleus, dorsomedial nucleus, perifornical regions, lateral nucleus, and the arcuate nucleus. |
2002-06-25 |
2023-08-12 |
rat |
| Hui-Yun Li, Hui-Wen Hwang, Yin-Hui H. Functional characterizations of cocaine- and amphetamine-regulated transcript mRNA expression in rat hypothalamus. Neuroscience letters. vol 323. issue 3. 2002-06-25. PMID:11959420. |
moreover, either fasting or diabetes attenuates cart mrna expression in the hypothalamus, demonstrating that cart mrna regulation is related to the fuel availability and peripheral hormonal status. |
2002-06-25 |
2023-08-12 |
rat |
| Hui-Yun Li, Hui-Wen Hwang, Yin-Hui H. Functional characterizations of cocaine- and amphetamine-regulated transcript mRNA expression in rat hypothalamus. Neuroscience letters. vol 323. issue 3. 2002-06-25. PMID:11959420. |
our findings suggest that the presence of cart mrna in specific cell groups of the hypothalamus plays a role in hypothalamic regulation of neuroendocrine functions. |
2002-06-25 |
2023-08-12 |
rat |
| Annette Sorensen, Clare L Adam, Pat A Findlay, Michel Marie, Louise Thomas, Maureen T Travers, Richard G Verno. Leptin secretion and hypothalamic neuropeptide and receptor gene expression in sheep. American journal of physiology. Regulatory, integrative and comparative physiology. vol 282. issue 4. 2002-04-16. PMID:11893629. |
thus the hypoleptinemia of lactation may activate npy orexigenic pathways and attenuate anorexigenic melanocortin and cart pathways in the hypothalamus to promote the hyperphagia of lactation. |
2002-04-16 |
2023-08-12 |
Not clear |
| Monica V Kumar, Teruhiko Shimokawa, Tim R Nagy, M Daniel Lan. Differential effects of a centrally acting fatty acid synthase inhibitor in lean and obese mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 4. 2002-03-25. PMID:11854492. |
these effects are associated with inhibition of fasting-induced up-regulation and down-regulation, respectively, of the expression of orexigenic (npy and agrp) and anorexigenic (pomc and cart) neuropeptide messages in the hypothalamus. |
2002-03-25 |
2023-08-12 |
mouse |
| B A Henry, A Rao, B A Ikenasio, K G Mountjoy, A J Tilbrook, I J Clark. Differential expression of cocaine- and amphetamine-regulated transcript and agouti related-protein in chronically food-restricted sheep. Brain research. vol 918. issue 1-2. 2002-01-04. PMID:11684040. |
the expression of cart was abundant throughout the hypothalamus but was not found in the arc. |
2002-01-04 |
2023-08-12 |
Not clear |
| B A Henry, A Rao, B A Ikenasio, K G Mountjoy, A J Tilbrook, I J Clark. Differential expression of cocaine- and amphetamine-regulated transcript and agouti related-protein in chronically food-restricted sheep. Brain research. vol 918. issue 1-2. 2002-01-04. PMID:11684040. |
thus, long-term changes in nutritional status have profound effects on the expression of agrp and cart in the hypothalamus. |
2002-01-04 |
2023-08-12 |
Not clear |
| R A Leslie, S J Sanders, S I Anderson, S Schuhler, T L Horan, F J Eblin. Appositions between cocaine and amphetamine-related transcript- and gonadotropin releasing hormone-immunoreactive neurons in the hypothalamus of the Siberian hamster. Neuroscience letters. vol 314. issue 3. 2002-01-04. PMID:11704296. |
recent in vitro studies have provided evidence that cocaine and amphetamine-related transcript (cart) pathways in the hypothalamus mediate the effects of leptin upon gonadotropin releasing hormone (gnrh) secretion. |
2002-01-04 |
2023-08-12 |
Not clear |
| H Volkoff, R E Pete. Characterization of two forms of cocaine- and amphetamine-regulated transcript (CART) peptide precursors in goldfish: molecular cloning and distribution, modulation of expression by nutritional status, and interactions with leptin. Endocrinology. vol 142. issue 12. 2001-12-20. PMID:11713200. |
central injection of leptin induced an increase in cart i mrna in the optic tectum, hypothalamus, and olfactory bulbs but had no effect on cart ii mrna expression in the brain. |
2001-12-20 |
2023-08-12 |
human |
| A W Bannon, J Seda, M Carmouche, J M Francis, M A Jarosinski, J Douglas. Multiple behavioral effects of cocaine- and amphetamine-regulated transcript (CART) peptides in mice: CART 42-89 and CART 49-89 differ in potency and activity. The Journal of pharmacology and experimental therapeutics. vol 299. issue 3. 2001-12-20. PMID:11714891. |
cocaine- and amphetamine-regulated transcript (cart) encodes a neuropeptide precursor protein that is highly abundant in cells of the hypothalamus. |
2001-12-20 |
2023-08-12 |
mouse |
| S Ludvigsen, L Thim, A M Blom, B S Wulf. Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold. Biochemistry. vol 40. issue 31. 2001-11-01. PMID:11478874. |
cocaine and amphetamine regulated transcript (cart) peptide has been shown to be an anorectic peptide that inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide y and regulated by leptin in the hypothalamus. |
2001-11-01 |
2023-08-12 |
Not clear |
| V Sergeyev, C Broberger, T Hökfel. Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus. Brain research. Molecular brain research. vol 90. issue 2. 2001-09-13. PMID:11406287. |
effect of lps administration on the expression of pomc, npy, galanin, cart and mch mrnas in the rat hypothalamus. |
2001-09-13 |
2023-08-12 |
rat |
| V Sergeyev, C Broberger, T Hökfel. Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus. Brain research. Molecular brain research. vol 90. issue 2. 2001-09-13. PMID:11406287. |
using in situ hybridization, the levels of mrnas encoding proopiomelanocortin (pomc), neuropeptide y (npy), galanin, melanin-concentrating hormone (mch) and cocaine- and amphetamine-regulated transcript (cart) were investigated in the rat hypothalamus after a single intraperitoneal dose (125 microg/kg) of lps. |
2001-09-13 |
2023-08-12 |
rat |
| H Zheng, C Patterson, H R Berthou. Fourth ventricular injection of CART peptide inhibits short-term sucrose intake in rats. Brain research. vol 896. issue 1-2. 2001-06-28. PMID:11277984. |
expression of cart (cocaine-amphetamine-regulated transcript) in the rat hypothalamus is modulated by nutritional status, and injection of synthetic cart peptide into the forebrain ventricular system suppresses food intake, indicating a possible role in hypothalamic control of energy homeostasis. |
2001-06-28 |
2023-08-12 |
rat |
| T Adage, A J Scheurink, S F de Boer, K de Vries, J P Konsman, F Kuipers, R A Adan, D G Baskin, M W Schwartz, G van Dij. Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331393. |
the obesity effects occurred despite a lack in neuropeptide expression responses in the neuroanatomical range selected across the arcuate (i.e., cart, pomc, and npy) and paraventricular (i.e., crh) hypothalamus. |
2001-06-21 |
2023-08-12 |
rat |
| M Niim. [The role of anorectic and orexigenic peptides(CART, NPY etc)]. Nihon rinsho. Japanese journal of clinical medicine. vol 59. issue 3. 2001-06-07. PMID:11268591. |
leptin receptors have been identified in cocaine and amphetamine-regulated transcript(cart), neuropeptide y(npy), galanin-containing neurons of the arcuate nucleus, respectively, and in corticotropin-releasing hormone(crh)-containing neurons of the paraventricular nucleus, suggesting that these peptides are mediators of leptin's action in the hypothalamus. |
2001-06-07 |
2023-08-12 |
Not clear |
| C F Elias, C E Lee, J F Kelly, R S Ahima, M Kuhar, C B Saper, J K Elmquis. Characterization of CART neurons in the rat and human hypothalamus. The Journal of comparative neurology. vol 432. issue 1. 2001-05-03. PMID:11241374. |
characterization of cart neurons in the rat and human hypothalamus. |
2001-05-03 |
2023-08-12 |
human |