| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arghya Mukherjee, Nishikant K Subhedar, Aurnab Ghos. Ontogeny of the cocaine- and amphetamine-regulated transcript (CART) neuropeptide system in the brain of zebrafish, Danio rerio. The Journal of comparative neurology. vol 520. issue 4. 2012-04-27. PMID:22009187. |
key neuroendocrine centers, like the preoptic area, hypothalamus, and pituitary, conspicuously show cart innervations, suggesting functions analogous to those demonstrated in other chordates. |
2012-04-27 |
2023-08-12 |
zebrafish |
| Elli Mikrouli, Gitta Wörtwein, Rana Soylu, Aleksander A Mathé, Åsa Petersé. Increased numbers of orexin/hypocretin neurons in a genetic rat depression model. Neuropeptides. vol 45. issue 6. 2012-03-19. PMID:21871662. |
we found that the total number of orexin-positive neurons was higher in the hypothalamus of female fsl rats compared to female frl rats, whereas no changes in the mch or cart populations could be detected between the strains. |
2012-03-19 |
2023-08-12 |
rat |
| S G Ruginsk, E T Uchoa, L L K Elias, J Antunes-Rodrigues, I J Llewellyn-Smit. Hypothalamic cocaine- and amphetamine-regulated transcript and corticotrophin releasing factor neurons are stimulated by extracellular volume and osmotic changes. Neuroscience. vol 186. 2012-01-30. PMID:21539900. |
therefore, this study aimed to evaluate, in experimental models of isotonic (i-eve) and hypertonic (h-eve) extracellular volume expansion and water deprivation (wd), the activation of cart- and corticotrophin releasing factor (crf)-immunoreactive neurons, as well as the relative expression of cart and crf mrnas in the paraventricular (pvn) and supraoptic (son) nuclei of the hypothalamus. |
2012-01-30 |
2023-08-12 |
rat |
| Sanaz Gabery, Karen Murphy, Kristofer Schultz, Clement T Loy, Elizabeth McCusker, Deniz Kirik, Glenda Halliday, Asa Petersé. Changes in key hypothalamic neuropeptide populations in Huntington disease revealed by neuropathological analyses. Acta neuropathologica. vol 120. issue 6. 2011-11-08. PMID:20821223. |
the increased expression of cart in the hypothalamus is consistent with a previous study showing increased cart levels in cerebrospinal fluid from hd patients. |
2011-11-08 |
2023-08-12 |
Not clear |
| Jian-Guo Cui, Gang-Bing Tang, De-Hua Wan. Hypothalamic neuropeptides, not leptin sensitivity, contributes to the hyperphagia in lactating Brandt's voles, Lasiopodomys brandtii. The Journal of experimental biology. vol 214. issue Pt 13. 2011-10-03. PMID:21653818. |
the serum leptin level and mrna expression of the long form of the leptin receptor (ob-rb), suppressor-of-cytokine-signalling-3 (socs-3), neuropeptide y (npy), agouti-related protein (agrp), pro-opiomelanocortin (pomc) and cocaine- and amphetamine-regulated transcript (cart) in the hypothalamus were examined on dioestrous, day 5, day 17 of lactation and day 27 (1 week after weaning) in brandt's voles. |
2011-10-03 |
2023-08-12 |
Not clear |
| K W S Ashwell, J K Ma. Distribution of CART (cocaine- and amphetamine-regulated transcript) peptide in mature and developing marsupial brain. Brain, behavior and evolution. vol 76. issue 2. 2011-09-26. PMID:20881368. |
both marsupials showed immunoreactivity to cart in the olfactory bulb, piriform cortex, extended amygdala, the supraoptic, paraventricular and arcuate nuclei of the hypothalamus, somatosensory and auditory nuclei of the brainstem, vagal/solitary complex, raphe obscurus and raphe pallidus and presumptive presympathetic neurons of the ventrolateral medulla, as has been seen in eutherians. |
2011-09-26 |
2023-08-12 |
Not clear |
| Jun Hou, De-Zhi Zheng, Ji-Yin Zhou, Shi-Wen Zho. Orexigenic effect of cocaine- and amphetamine-regulated transcript (CART) after injection into hypothalamic nuclei in streptozotocin-diabetic rats. Clinical and experimental pharmacology & physiology. vol 37. issue 10. 2011-09-02. PMID:20626417. |
the aim of the present study was to investigate the orexigenic effect of cocaine- and amphetamine-regulated transcript (cart) peptide on feeding regulation following its injection into discrete nuclei of the hypothalamus. |
2011-09-02 |
2023-08-12 |
rat |
| Fei Ling, Liqiong Wei, Tao Wang, Yaosheng Chen, Xiaoping Zhu, Jiaqi Li, Tingting Liu, Hongli Du, Haibo Wang, Jufang Wan. Cloning and characterization of the 5'-flanking region of the pig cocaine- and amphetamine-regulated transcript gene. DNA and cell biology. vol 30. issue 2. 2011-03-11. PMID:21091201. |
our rt-pcr results revealed that the pig cart gene was ubiquitously expressed in all examined tissues including hypothalamus, m. longissimus, backfat, heart, liver, spleen, lung, kidney, stomach, bladder, belly fat, brain, large intestine, lymph, and skin. |
2011-03-11 |
2023-08-12 |
mouse |
| Fei Ling, Liqiong Wei, Tao Wang, Yaosheng Chen, Xiaoping Zhu, Jiaqi Li, Tingting Liu, Hongli Du, Haibo Wang, Jufang Wan. Cloning and characterization of the 5'-flanking region of the pig cocaine- and amphetamine-regulated transcript gene. DNA and cell biology. vol 30. issue 2. 2011-03-11. PMID:21091201. |
real-time quantitative pcr experiments revealed that the cdna level of cart in both the hypothalamus and backfat of adult landrace pig (lean-type) was significantly higher than that of chinese indigenous lantang pig (fat-type), and it was in the hypothalamus where the highest expression of cart was observed for both adult lantang and landrace pigs, compared with backfat and m. longissimus muscle. |
2011-03-11 |
2023-08-12 |
mouse |
| Marta Conde-Sieira, Maria J Agulleiro, Ariel J Aguilar, Jesús M Míguez, José M Cerdá-Reverter, José L Soenga. Effect of different glycaemic conditions on gene expression of neuropeptides involved in control of food intake in rainbow trout; interaction with stress. The Journal of experimental biology. vol 213. issue Pt 22. 2011-02-24. PMID:21037065. |
to assess mechanisms relating to food intake and glucosensing in fish, and their interaction with stress, we evaluated changes in the expression of orexigenic (npy) and anorexigenic (pomc, cart and crf) peptides in central glucosensing areas (hypothalamus and hindbrain) of rainbow trout subjected to normoglycaemic (control), hypoglycaemic (4 mg insulin kg(-1)) or hyperglycaemic (500 mg glucose kg(-1)) conditions for 6 h under normal stocking density (nsd; 10 kg fish mass m(-3)) or under stress conditions induced by high stocking density (hsd; 70 kg fish mass m(-3)). |
2011-02-24 |
2023-08-12 |
Not clear |
| Marta Conde-Sieira, Maria J Agulleiro, Ariel J Aguilar, Jesús M Míguez, José M Cerdá-Reverter, José L Soenga. Effect of different glycaemic conditions on gene expression of neuropeptides involved in control of food intake in rainbow trout; interaction with stress. The Journal of experimental biology. vol 213. issue Pt 22. 2011-02-24. PMID:21037065. |
hyperglycaemic nsd conditions resulted in decreased mrna levels of npy and increased levels of cart and pomc in the hypothalamus as well as increased mrna levels of cart and crf in the hindbrain compared with hypo- and normoglycaemic conditions. |
2011-02-24 |
2023-08-12 |
Not clear |
| Marta Conde-Sieira, Maria J Agulleiro, Ariel J Aguilar, Jesús M Míguez, José M Cerdá-Reverter, José L Soenga. Effect of different glycaemic conditions on gene expression of neuropeptides involved in control of food intake in rainbow trout; interaction with stress. The Journal of experimental biology. vol 213. issue Pt 22. 2011-02-24. PMID:21037065. |
hsd conditions in normoglycaemic fish induced marked changes in the expression of all peptides assessed: mrna levels of npy and crf increased and mrna levels of pomc and cart decreased in the hypothalamus, whereas the expression of all four peptides (npy, pomc, cart and crf) decreased in the hindbrain. |
2011-02-24 |
2023-08-12 |
Not clear |
| Marta Conde-Sieira, Maria J Agulleiro, Ariel J Aguilar, Jesús M Míguez, José M Cerdá-Reverter, José L Soenga. Effect of different glycaemic conditions on gene expression of neuropeptides involved in control of food intake in rainbow trout; interaction with stress. The Journal of experimental biology. vol 213. issue Pt 22. 2011-02-24. PMID:21037065. |
furthermore, hsd conditions altered the response to changes in glycaemia of npy and pomc expression in the hypothalamus and cart expression in the hypothalamus and the hindbrain. |
2011-02-24 |
2023-08-12 |
Not clear |
| Kartik T Nakhate, Dadasaheb M Kokare, Praful S Singru, Amit G Taksande, Swati D Kotwal, Nishikant K Subheda. Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis. Pharmacology, biochemistry, and behavior. vol 97. issue 2. 2011-02-03. PMID:20833197. |
cocaine- and amphetamine-regulated transcript peptide (cart) is a major anorectic agent present in the hypothalamus. |
2011-02-03 |
2023-08-12 |
rat |
| Kartik T Nakhate, Dadasaheb M Kokare, Praful S Singru, Amit G Taksande, Swati D Kotwal, Nishikant K Subheda. Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis. Pharmacology, biochemistry, and behavior. vol 97. issue 2. 2011-02-03. PMID:20833197. |
the results suggest that, cancerous condition might down-regulate the cart system in the hypothalamus. |
2011-02-03 |
2023-08-12 |
rat |
| Irit Hochberg, Ze'ev Hochber. Hypothalamic obesity. Endocrine development. vol 17. 2010-12-16. PMID:19955767. |
hyob complicates disorders related to the hypothalamus, including those that cause structural damage to the hypothalamus, pituitary macroadenoma with suprasellar extension, glioma, meningioma, teratoma, germ cell tumors, radiotherapy, prader-willi syndrome, and mutations in leptin, leptin receptor, pomc, mc4r and cart genes. |
2010-12-16 |
2023-08-12 |
Not clear |
| Szilamér Ferenczi, Cristina Núñez, Bernadett Pintér-Kübler, Anna Földes, Fátima Martín, Vera Ladnyánszky Márkus, M Victoria Milanés, Krisztina J Kovác. Changes in metabolic-related variables during chronic morphine treatment. Neurochemistry international. vol 57. issue 3. 2010-11-04. PMID:20600437. |
however, morphine-induced long-term metabolic alterations were not accompanied with any significant changes in the expression of anorexigenic neuropeptides pomc and cart in the hypothalamus and in the brainstem. |
2010-11-04 |
2023-08-12 |
rat |
| N López, J Sánchez, C Picó, A Palou, F Serr. Dietary l-leucine supplementation of lactating rats results in a tendency to increase lean/fat ratio associated to lower orexigenic neuropeptide expression in hypothalamus. Peptides. vol 31. issue 7. 2010-09-14. PMID:20347902. |
hypothalamus was collected at the end of lactation, and the expression of neuropeptide y (npy), agouti-related protein (agrp) pro-opiomelanocortin (pomc), cocaine and amphetamine regulated transcript (cart), insulin receptor (insr), ghrelin receptor (gshr), melanocortin receptor (mcr4), leptin receptor (ob-rb) and suppressor of cytokine signaling 3 (socs3) were analyzed. |
2010-09-14 |
2023-08-12 |
rat |
| Niamh X Cawley, Tulin Yanik, Alicja Woronowicz, Weizhong Chang, Joan C Marini, Y Peng Lo. Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density. American journal of physiology. Endocrinology and metabolism. vol 299. issue 2. 2010-07-21. PMID:20460579. |
in the hypothalamus, mature cart, a peptide involved in eating behavior and implicated in bone metabolism, was undetectable. |
2010-07-21 |
2023-08-12 |
mouse |
| E Zayra Millan, Teri M Furlong, Gavan P McNall. Accumbens shell-hypothalamus interactions mediate extinction of alcohol seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 13. 2010-04-22. PMID:20357113. |
within hypothalamus, there was an increase in the number of orexin and cart cells expressing c-fos. |
2010-04-22 |
2023-08-12 |
rat |