| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kely de Picoli Souza, Elton D da Silva, Elice C Batista, Felipe C G Reis, Sylvia M A Silva, Charlles H M Castro, Jaqueline Luz, Jorge L Pesquero, Edson L Dos Santos, João B Pesquer. Early pharmacological inhibition of angiotensin-I converting enzyme activity induces obesity in adulthood. Frontiers in pharmacology. vol 6. 2015-04-30. PMID:25926796. |
molecular analyses revealed that enalapril treatment increases neuropeptide y (npy) and cocaine- and amphetamine-regulated transcript (cart) gene expression in hypothalamus, fatty acid synthase (fas), and hormone-sensitive lipase (hsl) gene expression in retroperitoneal wat, and decreases peroxixome proliferators-activated receptor (ppar)γ, pparα, uncoupling protein (ucp)2, and ucp3 gene expression in wat. |
2015-04-30 |
2023-08-13 |
rat |
| Pia S Petersen, Xia Lei, Marcus M Seldin, Susana Rodriguez, Mardi S Byerly, Andrew Wolfe, Scott Whitlock, G William Won. Dynamic and extensive metabolic state-dependent regulation of cytokine expression and circulating levels. American journal of physiology. Regulatory, integrative and comparative physiology. vol 307. issue 12. 2015-02-11. PMID:25320344. |
changes in food intake were not accompanied by acute alterations in orexigenic (npy and agrp) and anorexigenic (pomc and cart) neuropeptide gene expression in the hypothalamus. |
2015-02-11 |
2023-08-13 |
mouse |
| Sarah M Tuziak, Matthew L Rise, Hélène Volkof. An investigation of appetite-related peptide transcript expression in Atlantic cod (Gadus morhua) brain following a Camelina sativa meal-supplemented feeding trial. Gene. vol 550. issue 2. 2014-11-21. PMID:25151310. |
growth and food intake were evaluated and the mrna expression of appetite-related hormones [pro-melanin-concentrating hormone (pmch), hypocretin (synonym: orexin, hcrt), neuropeptide y (npy) and cocaine- and amphetamine-regulated transcript (cart)] was assessed using quantitative real-time pcr in brain regions related to food intake regulation (telencephalon/preoptic area, optic tectum/thalamus and hypothalamus). |
2014-11-21 |
2023-08-13 |
Not clear |
| Nabilah I Chowdhury, Renan P Souza, Arun K Tiwari, Eva J Brandl, Michelle Sicard, Herbert Y Meltzer, Jeffrey A Lieberman, James L Kennedy, Daniel J Mülle. Investigation of melanocortin system gene variants in antipsychotic-induced weight gain. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 15. issue 3. 2014-10-31. PMID:24564533. |
distinct populations of neurons expressed in the hypothalamus, including the cocaine- and amphetamine-regulated transcript (cart), the polypeptide pro-opiomelanocortin (pomc) and the agouti-related protein (agrp), have regulatory roles in weight control and energy homeostasis. |
2014-10-31 |
2023-08-12 |
Not clear |
| Mitsuhiro Yoshimura, Marina Hagimoto, Takanori Matsuura, Junichi Ohkubo, Motoko Ohno, Takashi Maruyama, Toru Ishikura, Hirofumi Hashimoto, Tetsuya Kakuma, Hironobu Yoshimatsu, Kiyoshi Terawaki, Yasuhito Uezono, Yumiko Toyohira, Nobuyuki Yanagihara, Yoichi Uet. Effects of food deprivation on the hypothalamic feeding-regulating peptides gene expressions in serotonin depleted rats. The journal of physiological sciences : JPS. vol 64. issue 2. 2014-10-21. PMID:24162946. |
pcpa pretreatment had no significant effect on basal levels of oxytocin, corticotropin-releasing hormone (crh), thyrotropin-releasing hormone (trh), pro-opiomelanocortin (pomc), cocaine and amphetamine-regulated transcript (cart), neuropeptide-y (npy), agouti-related protein (agrp), melanin-concentrating hormone (mch) or orexin in the hypothalamus. |
2014-10-21 |
2023-08-12 |
rat |
| Mitsuhiro Yoshimura, Marina Hagimoto, Takanori Matsuura, Junichi Ohkubo, Motoko Ohno, Takashi Maruyama, Toru Ishikura, Hirofumi Hashimoto, Tetsuya Kakuma, Hironobu Yoshimatsu, Kiyoshi Terawaki, Yasuhito Uezono, Yumiko Toyohira, Nobuyuki Yanagihara, Yoichi Uet. Effects of food deprivation on the hypothalamic feeding-regulating peptides gene expressions in serotonin depleted rats. The journal of physiological sciences : JPS. vol 64. issue 2. 2014-10-21. PMID:24162946. |
these results suggest that the serotonergic system in the hypothalamus may be involved in the gene expression of pomc, cart, and npy related to feeding behavior. |
2014-10-21 |
2023-08-12 |
rat |
| Fatiha Chigr, Fatima Rachidi, Catherine Tardivel, Mohamed Najimi, Emmanuel Moys. Modulation of orexigenic and anorexigenic peptides gene expression in the rat DVC and hypothalamus by acute immobilization stress. Frontiers in cellular neuroscience. vol 8. 2014-08-07. PMID:25100947. |
we studied the long term effects of a single exposure to immobilization stress (is) (1 h) on the expression of anorexigenic (pro-opiomelanocortin: pomc and cocaine amphetamine related transcript: cart) and orexigenic (neuropeptide y:npy, agouti related peptide: agrp) factors in hypothalamus and dorso vagal complex (dvc). |
2014-08-07 |
2023-08-13 |
rat |
| Fatiha Chigr, Fatima Rachidi, Catherine Tardivel, Mohamed Najimi, Emmanuel Moys. Modulation of orexigenic and anorexigenic peptides gene expression in the rat DVC and hypothalamus by acute immobilization stress. Frontiers in cellular neuroscience. vol 8. 2014-08-07. PMID:25100947. |
we showed, by using rt-pcr that in the hypothalamus, that the mrnas of pomc and cart were up-regulated at the end of is and up to 24 h. this up regulation persists until 48-72 h after is for cart only. |
2014-08-07 |
2023-08-13 |
rat |
| Fatiha Chigr, Fatima Rachidi, Catherine Tardivel, Mohamed Najimi, Emmanuel Moys. Modulation of orexigenic and anorexigenic peptides gene expression in the rat DVC and hypothalamus by acute immobilization stress. Frontiers in cellular neuroscience. vol 8. 2014-08-07. PMID:25100947. |
the comparison between the expression profiles of anorexigenic and the two orexigenic peptides investigated shows the presence of a parallelism between that of pomc and agrp and that of cart and npy when each brain region (hypothalamus and dvc) is considered separately. |
2014-08-07 |
2023-08-13 |
rat |
| Lauren E MacDonald, Sarah L Alderman, Sarah Kramer, Patrick T K Woo, Nicholas J Bernie. Hypoxemia-induced leptin secretion: a mechanism for the control of food intake in diseased fish. The Journal of endocrinology. vol 221. issue 3. 2014-07-25. PMID:24741070. |
in the hypothalamus, peak anorexia was associated with decreases in mrna levels of neuropeptide y (npy) and cocaine- and amphetamine-regulated transcript (cart), and increases in agouti-related protein (agrp) and pro-opiomelanocortin a2 (pomc). |
2014-07-25 |
2023-08-13 |
Not clear |
| Sayaka Akieda-Asai, Paul-Emile Poleni, Yukari Dat. Coinjection of CCK and leptin reduces food intake via increased CART/TRH and reduced AMPK phosphorylation in the hypothalamus. American journal of physiology. Endocrinology and metabolism. vol 306. issue 11. 2014-07-22. PMID:24735891. |
in addition, coadministration of these hormones significantly increased mrna levels of anorectic cocaine- and amphetamine-regulated transcript (cart) and thyrotropin-releasing hormone (trh) in the hypothalamus. |
2014-07-22 |
2023-08-13 |
rat |
| Ja Hye Kim, Jin-Ho Cho. Pathophysiology and clinical characteristics of hypothalamic obesity in children and adolescents. Annals of pediatric endocrinology & metabolism. vol 18. issue 4. 2014-06-24. PMID:24904871. |
hypothalamic obesity is a result of impairment in the hypothalamic regulatory centers of body weight and energy expenditure, and is caused by structural damage to the hypothalamus, radiotherapy, prader-willi syndrome, and mutations in the lep, lepr, pomc, mc4r and cart genes. |
2014-06-24 |
2023-08-13 |
Not clear |
| Chengrong Zhong, Yanlong Song, Yaping Wang, Tanglin Zhang, Ming Duan, Yongming Li, Lanjie Liao, Zuoyan Zhu, Wei H. Increased food intake in growth hormone-transgenic common carp (Cyprinus carpio L.) may be mediated by upregulating Agouti-related protein (AgRP). General and comparative endocrinology. vol 192. 2014-06-10. PMID:23583469. |
in this study, we observed feeding behavior of tg and non-transgenic (nt) common carp, and analyzed the mrna expression levels of npy, agrp i, orexin, pomc, cck, and cart i in the hypothalamus and telencephalon after behavioral observation. |
2014-06-10 |
2023-08-12 |
Not clear |
| Nicole A Babichuk, Hélène Volkof. Changes in expression of appetite-regulating hormones in the cunner (Tautogolabrus adspersus) during short-term fasting and winter torpor. Physiology & behavior. vol 120. 2014-05-26. PMID:23831740. |
in order to better understand the mechanisms regulating appetite/fasting in these fish, quantitative real-time pcr was used to measure transcript expression levels of four appetite-regulating hormones: npy, cart, orexin and cck in the forebrain (hypothalamus and telencephalon) and cck in the gut of fed, short-term summer fasted, and natural winter torpor cunners. |
2014-05-26 |
2023-08-12 |
Not clear |
| Luigi Brunetti, Claudio Ferrante, Giustino Orlando, Lucia Recinella, Sheila Leone, Annalisa Chiavaroli, Chiara Di Nisio, Rugia Shohreh, Fabio Manippa, Adriana Ricciuti, Adriano Mollica, Michele Vacc. Orexigenic effects of endomorphin-2 (EM-2) related to decreased CRH gene expression and increased dopamine and norepinephrine activity in the hypothalamus. Peptides. vol 48. 2014-05-19. PMID:23916912. |
we studied the effects of em-2 injected into the arcuate nucleus (arc) of the hypothalamus on feeding behavior and gene expression of orexigenic [agouti-related peptide (agrp), neuropeptide y (npy) and orexin-a] and anorexigenic [cocaine and amphetamine-regulated transcript (cart), corticotrophin releasing hormone (crh) and proopiomelanocortin (pomc)] peptides in male wistar rats fed a standard laboratory diet. |
2014-05-19 |
2023-08-12 |
rat |
| Honggui Li, Xin Guo, Hang Xu, Shih-Lung Woo, Vera Halim, Caurnel Morgan, Chaodong W. A role for inducible 6-phosphofructo-2-kinase in the control of neuronal glycolysis. The Journal of nutritional biochemistry. vol 24. issue 6. 2014-04-24. PMID:23246158. |
in the hypothalamus, re-feeding also decreased the phosphorylation of amp-activated protein kinase (ampk) (thr172) and the mrna levels of agouti-related protein (agrp), and increased the mrna levels of cocaine-amphetamine-related transcript (cart). |
2014-04-24 |
2023-08-12 |
mouse |
| Kartik T Nakhate, Nishikant K Subhedar, Ashish P Bharne, Praful S Singru, Dadasaheb M Kokar. Involvement of cocaine- and amphetamine-regulated transcript peptide in the hyperphagic and body weight promoting effects of allopregnanolone in rats. Brain research. vol 1532. 2014-03-21. PMID:23933097. |
since gaba-a receptors are present on the peptidergic neurons in the hypothalamus, we were interested in finding out if allo and neuropeptide cocaine- and amphetamine-regulated transcript (cart) interact and influence feeding behavior. |
2014-03-21 |
2023-08-12 |
rat |
| Hélène Volkof. The effects of amphetamine injections on feeding behavior and the brain expression of orexin, CART, tyrosine hydroxylase (TH) and thyrotropin releasing hormone (TRH) in goldfish (Carassius auratus). Fish physiology and biochemistry. vol 39. issue 4. 2014-03-05. PMID:23229307. |
in the hypothalamus, the expression of orexin was down-regulated, and both cart 1 and cart 2 expressions were up-regulated in amphetamine-treated fish (50 μg/g) as compared to saline-injected fish, but amphetamine treatment had no effect on either hypothalamic th or trh expression. |
2014-03-05 |
2023-08-12 |
Not clear |
| Luigi Brunetti, Giustino Orlando, Claudio Ferrante, Lucia Recinella, Sheila Leone, Annalisa Chiavaroli, Chiara Di Nisio, Rugia Shohreh, Fabio Manippa, Adriana Ricciuti, Michele Vacc. Orexigenic effects of omentin-1 related to decreased CART and CRH gene expression and increased norepinephrine synthesis and release in the hypothalamus. Peptides. vol 44. 2013-12-31. PMID:23538212. |
orexigenic effects of omentin-1 related to decreased cart and crh gene expression and increased norepinephrine synthesis and release in the hypothalamus. |
2013-12-31 |
2023-08-12 |
rat |
| Luigi Brunetti, Giustino Orlando, Claudio Ferrante, Lucia Recinella, Sheila Leone, Annalisa Chiavaroli, Chiara Di Nisio, Rugia Shohreh, Fabio Manippa, Adriana Ricciuti, Michele Vacc. Orexigenic effects of omentin-1 related to decreased CART and CRH gene expression and increased norepinephrine synthesis and release in the hypothalamus. Peptides. vol 44. 2013-12-31. PMID:23538212. |
in conclusion, the orexigenic effects of omentin-1 could be related, at least in part, to decreased cart and crh gene expression and increased ne synthesis and release in the hypothalamus. |
2013-12-31 |
2023-08-12 |
rat |