| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alejandra Monserrat Rodríguez-Ramírez, Valente Cedillo-Ríos, Marco Antonio Sanabrais-Jiménez, Claudia Becerra-Palars, Sandra Hernández-Muñoz, Hiram Ortega-Ortíz, Beatriz Camarena-Medelli. Association of BDNF risk variant and dorsolateral cortical thickness with long-term treatment response to valproate in type I bipolar disorder: An exploratory study. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2023-11-03. PMID:37921405. |
one of valproate's suggested mechanisms of action involves the brain-derived neurotrophic factor (bdnf), expressed in the brain areas regulating emotions, such as the prefrontal cortex. |
2023-11-03 |
2023-11-08 |
Not clear |
| Alejandra Monserrat Rodríguez-Ramírez, Valente Cedillo-Ríos, Marco Antonio Sanabrais-Jiménez, Claudia Becerra-Palars, Sandra Hernández-Muñoz, Hiram Ortega-Ortíz, Beatriz Camarena-Medelli. Association of BDNF risk variant and dorsolateral cortical thickness with long-term treatment response to valproate in type I bipolar disorder: An exploratory study. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2023-11-03. PMID:37921405. |
nonetheless, data about the role of bdnf in lttr and its implications in the structure of the dorsolateral prefrontal cortex (dlpfc) is scarce. |
2023-11-03 |
2023-11-08 |
Not clear |
| A S Solomina, L G Kolik, A V Rodina, I O Logvinov, V G Kon'kov, V S Kudrin, T A Antipova, A D Durne. Chronic Ethanol Consumption by Rats before Mating Affects Working Memory in the Offspring. Bulletin of experimental biology and medicine. vol 175. issue 5. 2023-11-01. PMID:37870659. |
memory impairment in f1 females was accompanied by a decrease in bdnf level in the hippocampus, but not in the prefrontal cortex. |
2023-11-01 |
2023-11-08 |
rat |
| Nadya Saad, Danielle Raviv, Tomer Mizrachi Zer-Aviv, Irit Akira. Cannabidiol Modulates Emotional Function and Brain-Derived Neurotrophic Factor Expression in Middle-Aged Female Rats Exposed to Social Isolation. International journal of molecular sciences. vol 24. issue 20. 2023-10-30. PMID:37895171. |
bdnf expression was found to be correlated with an antidepressant (in the nac) and an anxiolytic (in the mpfc, bla, nac) phenotype, and with learning improvement in the pfc. |
2023-10-30 |
2023-11-08 |
human |
| Lucia Caffino, Francesca Mottarlini, Alessandro Piva, Beatrice Rizzi, Fabio Fumagalli, Cristiano Chiamuler. Temporal dynamics of BDNF signaling recruitment in the rat prefrontal cortex and hippocampus following a single infusion of a translational dose of ketamine. Neuropharmacology. 2023-10-20. PMID:37858883. |
temporal dynamics of bdnf signaling recruitment in the rat prefrontal cortex and hippocampus following a single infusion of a translational dose of ketamine. |
2023-10-20 |
2023-11-08 |
rat |
| Lucia Caffino, Francesca Mottarlini, Alessandro Piva, Beatrice Rizzi, Fabio Fumagalli, Cristiano Chiamuler. Temporal dynamics of BDNF signaling recruitment in the rat prefrontal cortex and hippocampus following a single infusion of a translational dose of ketamine. Neuropharmacology. 2023-10-20. PMID:37858883. |
we focused on the first 24 h after infusion to finely dissect potential differences in the contribution of bdnf signaling pathway in prefrontal cortex and hippocampus, two brain regions involved in the antidepressant effects of ketamine. |
2023-10-20 |
2023-11-08 |
rat |
| Lucia Caffino, Francesca Mottarlini, Alessandro Piva, Beatrice Rizzi, Fabio Fumagalli, Cristiano Chiamuler. Temporal dynamics of BDNF signaling recruitment in the rat prefrontal cortex and hippocampus following a single infusion of a translational dose of ketamine. Neuropharmacology. 2023-10-20. PMID:37858883. |
we have captured previously unknown dynamics of the early effects of ketamine showing rapid activation/deactivation of bdnf and its downstream signaling in prefrontal cortex and hippocampus, following a precise temporal profile. |
2023-10-20 |
2023-11-08 |
rat |
| Helia Aghamiri, Majid Jafari-Sabet, Mahmood Hoorman. Ameliorative Effect of Cannabidiol on Topiramate-Induced Memory Loss: The Role of Hippocampal and Prefrontal Cortical NMDA Receptors and CREB/BDNF Signaling Pathways in Rats. Neurochemical research. 2023-10-09. PMID:37814133. |
western blot analysis was used to evaluate variations in brain-derived neurotrophic factor (bdnf) and phosphorylated cyclic amp response element-binding protein (pcreb)/creb ratio in the prefrontal cortex (pfc) and hippocampus (hpc). |
2023-10-09 |
2023-10-15 |
rat |
| Helia Aghamiri, Majid Jafari-Sabet, Mahmood Hoorman. Ameliorative Effect of Cannabidiol on Topiramate-Induced Memory Loss: The Role of Hippocampal and Prefrontal Cortical NMDA Receptors and CREB/BDNF Signaling Pathways in Rats. Neurochemical research. 2023-10-09. PMID:37814133. |
similarly, the sub-effective doses of nmda plus cbd (10 mg/kg) could improve the topiramate-induced memory loss along with an enhancement in bdnf and pcreb expression in the pfc and hpc. |
2023-10-09 |
2023-10-15 |
rat |
| Helia Aghamiri, Majid Jafari-Sabet, Mahmood Hoorman. Ameliorative Effect of Cannabidiol on Topiramate-Induced Memory Loss: The Role of Hippocampal and Prefrontal Cortical NMDA Receptors and CREB/BDNF Signaling Pathways in Rats. Neurochemical research. 2023-10-09. PMID:37814133. |
contrarily, the administration of sub-effective doses of the nmdar antagonist (mk-801) diminished the protective effects of cbd (20 mg/kg) on topiramate-induced memory loss associated with decreased bdnf and pcreb levels in the pfc and hpc. |
2023-10-09 |
2023-10-15 |
rat |
| Yangyang Xu, Jie Zhang, Linyao Yu, Wei Zhang, Yingtian Zhang, Yaoqin Shi, Shuping Zhang, Chunmei Li, Jingwei Tia. Engeletin alleviates depression-like phenotype by increasing synaptic plasticity via the BDNF-TrkB-mTORC1 signalling pathway. Journal of cellular and molecular medicine. 2023-10-06. PMID:37799103. |
changes in prefrontal cortex (pfc) spine density, synaptic plasticity-linked protein expressions and the brain-derived neurotrophic factor (bdnf)-tyrosine kinase b (trkb)- mammalian target of rapamycin complex 1 (mtorc1) signalling pathway after chronic stress and engeletin treatment were then investigated. |
2023-10-06 |
2023-10-07 |
mouse |
| William Almaguer-Melian, Daymara Mercerón-Martinez, Esteban Alberti-Amador, Laura Alacán-Ricardo, Javier Curi de Bardet, Norma Orama-Rojo, Arturo Ernesto Vergara-Piña, Idalia Herrera Estrada, Jorge A Bergad. Learning induces EPO/EPOr expression in memory relevant brain areas, whereas exogenously applied EPO promotes remote memory consolidation. Synapse (New York, N.Y.). 2023-10-05. PMID:37794768. |
data show that learning induces epo/epor expression increase linked to memory extent, exogenous epo prolongs memory up to 21 days; and prefrontal cortex bdnf expression at 24 h and in the hippocampus at 21 days, whereas arc expression increases at 21 days in the hippocampus and prefrontal cortex. |
2023-10-05 |
2023-10-07 |
Not clear |
| Zubeyde Ercan, Ozgur Bulmus, Emine Kacar, Ihsan Serhatlioglu, Gokhan Zorlu, Haluk Kelestimu. Treadmill Exercise Improves Behavioral and Neurobiological Alterations in Restraint-Stressed Rats. Journal of molecular neuroscience : MN. 2023-10-04. PMID:37794307. |
brain-derived neurotrophic factor (bdnf), dopamine receptors, and serotonin receptor (htr2a) gene expression in the prefrontal cortex, corpus striatum, and hypothalamus were decreased by crs. |
2023-10-04 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
systemic administration of nicotine at a dose of 0.5 mg/kg induced an anxiogenic-like response associated with decreased bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
intra-md microinjection of apomorphine (0.1-0.3 μg/rat) induced an anxiogenic-like response, while apomorphine inhibited nicotine-induced anxiogenic-like behaviors associated with increased hippocampal and pfc bdnf expression levels. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
interestingly, the blockade of the vh or the pfc nmda receptors via the microinjection of d-ap5 (0.3-0.5 μg/rat) into the targeted sites reversed the inhibitory effect of apomorphine (0.5 μg/rat, intra-md) on the nicotine response and led to the decrease of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
these findings suggest that the functional interaction between the md dopaminergic d1/d2-like and the vh/pfc glutamatergic nmda receptors may be partially involved in the anxiogenic-like effects of nicotine, likely via the alteration of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Omar Gammoh, Esam Y Qnais, Rabaa Y Athamneh, Bilal Al-Jaidi, Deniz Al-Tawalbeh, Sara Altaber, Abdelrahim Alqudah, Alaa A A Aljabali, Murtaza M Tambuwal. Unraveling the Potential of Isorhamnetin as an Adjuvant in Depression Treatment with Escitalopram. Current issues in molecular biology. vol 45. issue 9. 2023-09-27. PMID:37754268. |
additionally, enzyme-linked immunosorbent assays were utilized to measure nrf2, bdnf, ho-1, no, and il-6 levels in the prefrontal cortex and hippocampus. |
2023-09-27 |
2023-10-07 |
mouse |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
this, study, then, was designed to analyze the long-term effects of early postnatal exposure to cmi on the expression of 5-ht1a, 5-ht2a, and 5-ht3 receptors, as well as bdnf and gr in the following brain regions: pfc, amygdala, hippocampus, and hypothalamus, which could be related to alterations in memory and learning, as evaluated using the novel object recognition (nor) and morris water maze (mwm). |
2023-09-15 |
2023-10-07 |
rat |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
expression of the 5-ht1a receptor increased in the hippocampus, amygdala, and hypothalamus, but decreased in the pfc, while the 5-ht2a and bdnf receptors decreased their expression in the pfc, amygdala, and hippocampus. |
2023-09-15 |
2023-10-07 |
rat |