| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sierra J Stringfield, Erin K Kirschmann, Mary M Torregross. Working memory performance predicts, but does not reduce, cocaine- and cannabinoid-seeking in adult male rats. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853853. |
we investigated whether working memory training could elevate bdnf levels in the prefrontal cortex and if this training would predict or protect against cocaine or cannabinoid seeking. |
2024-06-10 |
2024-06-14 |
rat |
| Christopher M Driskill, Jessica E Childs, Aarron J Phensy, Sierra R Rodriguez, John T O'Brien, Kathy L Lindquist, Aurian Naderi, Bogdan Bordieanu, Jacqueline F McGinty, Sven Kroene. Vagus nerve stimulation (VNS) modulates synaptic plasticity in the infralimbic cortex via Trk-B receptor activation to reduce drug-seeking in male rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-05-08. PMID:38719446. |
rats that received a single extinction session with vns showed elevated bdnf levels in the medial pfc as determined via an enzyme-linked immunosorbent assay (elisa). |
2024-05-08 |
2024-05-27 |
rat |
| Hong-Bao Li, Meng-Lu Xu, Wen-Jie Xia, Yuan-Yuan Dong, Bo Peng, Qing Su, Xiao-Min Wang, Jia-Yue Yu, Ya-Nan Gao, Jun-Zhe Wu, Meng-Yue Xu, Jin-Bao Yang, Zhi-Ming Dai, Lei Chen, Ying Li, Juan Ba. Antihypertensive treatment during pregnancy induces long-term changes in gut microbiota and the behaviors of the attention deficit hyperactivity disorder offspring. Toxicology and applied pharmacology. 2024-04-28. PMID:38679241. |
lc-ms/ms and immunohistochemistry assays suggested elevated expression of brain derived neurotrophic factor (bdnf) and dopamine in the prefrontal cortex and striatum of offspring exposed to captopril/ labetalol, which may account for the improvement of the offspring's psychiatric functions. |
2024-04-28 |
2024-05-01 |
rat |
| Taylor S Campbell, Katelyn Donoghue, Tania L Rot. Unlocking the epigenome: Stress and exercise induced Bdnf regulation in the prefrontal cortex. Neurotoxicology and teratology. 2024-04-22. PMID:38648864. |
unlocking the epigenome: stress and exercise induced bdnf regulation in the prefrontal cortex. |
2024-04-22 |
2024-04-26 |
rat |
| Taylor S Campbell, Katelyn Donoghue, Tania L Rot. Unlocking the epigenome: Stress and exercise induced Bdnf regulation in the prefrontal cortex. Neurotoxicology and teratology. 2024-04-22. PMID:38648864. |
to that end, the current study investigated the effect of an adult voluntary wheel running intervention on bdnf methylation and expression in the prefrontal cortex of rats who experienced aversive caregiving in infancy. |
2024-04-22 |
2024-04-26 |
rat |
| Taylor S Campbell, Katelyn Donoghue, Tania L Rot. Unlocking the epigenome: Stress and exercise induced Bdnf regulation in the prefrontal cortex. Neurotoxicology and teratology. 2024-04-22. PMID:38648864. |
keywords: early life stress, bdnf, exercise, prefrontal cortex. |
2024-04-22 |
2024-04-26 |
rat |
| Scheila Iria Kraus, Jeane Bachi Ferreira, Angela Patricia França, Vinícius Alexandre Wippel, Rodrigo Bainy Leal, Raquel Oppermann, Michele Debiasi Alberton, Morgana Duarte da Silv. Pharmacological Evidence of Eugenia Brasiliensis Leaves in a Reserpine-Induced Fibromyalgia Model: Antinociceptive, Emotional, Anti-Inflammatory, and Neurotrophic Effects. Molecular neurobiology. 2024-04-19. PMID:38639862. |
finally, we observed a reduction in inflammatory cytokines in the hippocampus of animals treated with heeb, while an increase in bdnf was observed in the prefrontal cortex (pfc). |
2024-04-19 |
2024-04-21 |
mouse |
| Sami Alzarea, Amna Khan, Patrick J Ronan, Kabirullah Lutfy, Shafiqur Rahma. The α-7 Nicotinic Receptor Positive Allosteric Modulator Alleviates Lipopolysaccharide Induced Depressive-like Behavior by Regulating Microglial Function, Trophic Factor, and Chloride Transporters in Mice. Brain sciences. vol 14. issue 3. 2024-03-28. PMID:38539677. |
therefore, we examined the effects of pnu120596, an α7 nachr positive allosteric modulator, on the expression of bdnf, kcc2, and nkcc1 in the hippocampus and prefrontal cortex using western blot analysis, immunofluorescence assay, and real-time polymerase chain reaction. |
2024-03-28 |
2024-03-30 |
mouse |
| Sami Alzarea, Amna Khan, Patrick J Ronan, Kabirullah Lutfy, Shafiqur Rahma. The α-7 Nicotinic Receptor Positive Allosteric Modulator Alleviates Lipopolysaccharide Induced Depressive-like Behavior by Regulating Microglial Function, Trophic Factor, and Chloride Transporters in Mice. Brain sciences. vol 14. issue 3. 2024-03-28. PMID:38539677. |
lps administration (1 mg/kg) resulted in increased expression of bdnf and the nkcc1/kcc2 ratio and decreased expression of kcc2 in the hippocampus and prefrontal cortex. |
2024-03-28 |
2024-03-30 |
mouse |
| Camila Berbert-Gomes, Júlia S Ramos, João G Silveira-Rodrigues, Daniel M M Leite, Bruno P Melo, Danusa D Soare. An acute bout of resistance exercise increases BDNF in hippocampus and restores the long-term memory of insulin-resistant rats. Experimental brain research. 2024-03-07. PMID:38453752. |
cognitive parameters were assessed by novel object recognition (nor) tasks, and biochemical analyses were performed to assess bdnf concentrations and inflammatory profile in the hippocampus and prefrontal cortex. |
2024-03-07 |
2024-03-10 |
rat |
| Shaohua You, Yishuang Wu, Yongxin Guo, Meng Wu, Mingzi Ran, Fuyang Cao, Xinyu Hao, Lujia Yang, Hong Zhang, Weidong Mi, Li Ton. Sevoflurane exerts antidepressant-like effects via the BDNF-TrkB pathway. Behavioural brain research. 2024-02-22. PMID:38387696. |
we then used western blotting to scrutinized the expression levels of proteins associated with the brain-derived neurotrophic factor (bdnf)-tryosine receptor kinase b (trkb) pathway in the hippocampus and prefrontal cortex. |
2024-02-22 |
2024-02-25 |
mouse |
| Christopher M Driskill, Jessica E Childs, Aarron J Phensy, Sierra R Rodriguez, John T O'Brien, Kathy L Lindquist, Aurian Naderi, Bogdan Bordieanu, Jacqueline F McGinty, Sven Kroene. Vagus nerve stimulation (VNS) modulates synaptic plasticity in the rat infralimbic cortex via Trk-B receptor activation to reduce drug-seeking. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328140. |
rats that received a single extinction session with vns showed elevated bdnf levels in the medial pfc as determined via an enzyme-linked immunosorbent assay (elisa). |
2024-02-08 |
2024-02-10 |
rat |
| Fernanda Frederico Gava, Raquel Jaconi De Carli, Solange Stork, Lucineia Gainski Danielski, Sandra Bonfante, Larissa Joaquim, Kiuanne Lino Lobo Metzker, Khiany Mathias, David Santos, Guilherme Darós, Marina Goulart, Rafael Mariano de Bitencourt, Josiane Somariva Prophiro, Cinara Ludvig Gonçalves, Jaqueline Generoso, Tatiana Barichello, Fabricia Petronilh. Cannabidiol effect on long-term brain alterations in septic rats: Involvement of PPARγ activation. Brain research. 2024-01-19. PMID:38242525. |
during this period, the survival rate was recorded, and at the end of 10 days, a memory test was performed, and the prefrontal cortex and hippocampus were removed to verify brain-derived neurotrophic factor (bdnf), cytokines (il-1β, il-6 and il-10), myeloperoxidase activity, nitrite nitrate concentration, and lipid and protein carbonylation and catalase activity. |
2024-01-19 |
2024-01-22 |
rat |
| Anjali Suman, Archisman Mahapatra, Priya Gupta, Shubhendu Shekhar Ray, Rahul Kumar Sing. Polystyrene microplastics induced disturbances in neuronal arborization and dendritic spine density in mice prefrontal cortex. Chemosphere. 2024-01-15. PMID:38224746. |
as well, spine density on the apical secondary branches along with mrna level of bdnf was significantly reduced in all the ps-mps treated pfc neurons, mainly at 1 ppm versus control. |
2024-01-15 |
2024-01-18 |
mouse |
| Anjali Suman, Archisman Mahapatra, Priya Gupta, Shubhendu Shekhar Ray, Rahul Kumar Sing. Polystyrene microplastics induced disturbances in neuronal arborization and dendritic spine density in mice prefrontal cortex. Chemosphere. 2024-01-15. PMID:38224746. |
these results suggest that ps-mps exposure affects overall basal neuronal arborization, with the highest levels at 1 and 10 ppm, followed by 0.1 ppm treated neurons, which may be related to the down-regulation of bdnf expression in pfc. |
2024-01-15 |
2024-01-18 |
mouse |
| Navid Fatahi, Majid Jafari-Sabet, Gelareh Vahabzadeh, Alireza Komak. Role of hippocampal and prefrontal cortical cholinergic transmission in combination therapy valproate and cannabidiol in memory consolidation in rats: involvement of CREB- BDNF signaling pathways. Naunyn-Schmiedeberg's archives of pharmacology. 2024-01-08. PMID:38189934. |
this study examined the effects of co-administration of cbd and valproate on memory consolidation, cholinergic transmission, and cyclic amp response element-binding protein (creb)-brain-derived neurotrophic factor (bdnf) signaling pathway in the prefrontal cortex (pfc) and hippocampus (hpc). |
2024-01-08 |
2024-01-10 |
rat |
| Handan Deng, Yongjun Yu, Qi Sha, Weiyi Sun, Lundan Liang, Feier Ren, Hua Ji, Xiangdi Shen, Xingli Fa. Construction of antibiotic-induced depression mice model and the function of intestinal microbiota. Frontiers in microbiology. vol 14. 2023-12-13. PMID:38088959. |
by using these antibiotics, the concentrations of norepinephrine (ne), 5-hydroxytryptamine (5-ht), and brain-derived neurotrophic factor (bdnf) in mice hippocampus and prefrontal cortex tissues were significantly decreased. |
2023-12-13 |
2023-12-17 |
mouse |
| Sanaz Dabiri, Denée T Mwendwa, Alfonso Campbel. Psychological and neurobiological mechanisms involved in the relationship between loneliness and cognitive decline in older adults. Brain, behavior, and immunity. 2023-11-26. PMID:38008386. |
bdnf gene expression was measured in the dorsolateral prefrontal cortex, cytokines were measured in serum, and the final consensus clinical diagnosis was identified at the time of death. |
2023-11-26 |
2023-11-28 |
human |
| Xiao Hu, Hui-Ling Zhao, Nurhumar Kurban, Yu Qin, Xi Chen, Su-Ying Cui, Yong-He Zhan. Reduction of BDNF Levels and Biphasic Changes in Glutamate Release in the Prefrontal Cortex Correlate with Susceptibility to Chronic Stress-Induced Anhedonia. eNeuro. vol 10. issue 11. 2023-11-23. PMID:37989582. |
reduction of bdnf levels and biphasic changes in glutamate release in the prefrontal cortex correlate with susceptibility to chronic stress-induced anhedonia. |
2023-11-23 |
2023-11-28 |
rat |
| Xiao Hu, Hui-Ling Zhao, Nurhumar Kurban, Yu Qin, Xi Chen, Su-Ying Cui, Yong-He Zhan. Reduction of BDNF Levels and Biphasic Changes in Glutamate Release in the Prefrontal Cortex Correlate with Susceptibility to Chronic Stress-Induced Anhedonia. eNeuro. vol 10. issue 11. 2023-11-23. PMID:37989582. |
we found that brain-derived neurotrophic factor (bdnf) levels in the pfc significantly decreased only in anhedonia-susceptible rats that were exposed to cms for 14, 21, and 35 d. |
2023-11-23 |
2023-11-28 |
rat |