Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Shi Bai, Zhong-Ming Ying, Jia-Kang Ying, Qin-Ying Zhang, Yu-Hang Lv, Zhong-Min W. Inhibition of 5-HT alleviates PTSD-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats. Journal of neurophysiology. 2024-08-07. PMID:39110517. |
rats exposed to single prolonged stress (sps) exhibited typical ptsd-like phenotypes, with decreased levels of 5-ht in the hippocampus and significant reductions in its downstream targets, brain-derived neurotrophic factor (bdnf) and trkb. |
2024-08-07 |
2024-08-10 |
rat |
Shi Bai, Zhong-Ming Ying, Jia-Kang Ying, Qin-Ying Zhang, Yu-Hang Lv, Zhong-Min W. Inhibition of 5-HT alleviates PTSD-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats. Journal of neurophysiology. 2024-08-07. PMID:39110517. |
additionally, it was discovered that the autophagy signaling pathway might be involved in regulating hippocampal bdnf in rats exposed to sps. |
2024-08-07 |
2024-08-10 |
rat |
Andrea Scolz, Elena Vezzoli, Michela Villa, Francesca Talpo, Jessica Cazzola, Francesca Raffin, Chiara Cordiglieri, Andrea Falqui, Giuseppe Pepe, Vittorio Maglione, Dario Besusso, Gerardo Biella, Chiara Zuccat. Neuroprotection by ADAM10 inhibition requires TrkB signaling in the Huntington's disease hippocampus. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-08-07. PMID:39112663. |
meanwhile, normalization of the active adam10 level increased the pool of synaptic bdnf protein and activated erk neuroprotective signaling in the hd hippocampus. |
2024-08-07 |
2024-08-10 |
mouse |
Andrea Scolz, Elena Vezzoli, Michela Villa, Francesca Talpo, Jessica Cazzola, Francesca Raffin, Chiara Cordiglieri, Andrea Falqui, Giuseppe Pepe, Vittorio Maglione, Dario Besusso, Gerardo Biella, Chiara Zuccat. Neuroprotection by ADAM10 inhibition requires TrkB signaling in the Huntington's disease hippocampus. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-08-07. PMID:39112663. |
notably, we report that administration of the trkb antagonist ana12 to hd hippocampal neurons reduced the beneficial effect of gi254023x, indicating that the bdnf receptor trkb contributes to mediate the neuroprotective activity exerted by adam10 inhibition in hd. |
2024-08-07 |
2024-08-10 |
mouse |
Zhangjie Wu, Ying Yin, Ruiyi Liu, Xianhui Li, Yan Sun, Suk-Yu Yau, Lei Wu, Yan Liu, Miroslav Adzic, Hailou Zhang, Gang Che. A refined formula derived from Jiawei-Xiaoyao Pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling. Journal of ethnopharmacology. 2024-08-02. PMID:39094756. |
furthermore, rapamycin, a selective inhibitor of mtor, blunted the rapid antidepressant-like effects and hippocampal bdnf signaling upregulation by gma conclusion: gma may serve as a refined formula from jwx, capable of inducing rapid antidepressant-like effects. |
2024-08-02 |
2024-08-06 |
mouse |
Dan Hou, Jialing Zhong, Yujie Hu, Guoshuai Yan. The effect of miR‑155‑5p on long‑term memory of sleep‑deprived mice through the BDNF/NF‑κB pathway. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087835. |
the observed cognitive deficits in the mice were associated with sd‑induced damage to the hippocampal tissue, leading to increased levels of mir‑155‑5p and decreased levels of bdnf. |
2024-08-01 |
2024-08-03 |
mouse |
Dan Hou, Jialing Zhong, Yujie Hu, Guoshuai Yan. The effect of miR‑155‑5p on long‑term memory of sleep‑deprived mice through the BDNF/NF‑κB pathway. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087835. |
the upregulation of bdnf effectively mitigated hippocampal damage by attenuating cell apoptosis and reducing inflammation levels in sd mice. |
2024-08-01 |
2024-08-03 |
mouse |
Amir Basiri, Saeid Izadi, Samaneh Kakhki, Vida Alikahni, Saeedeh Askarian, Farimah Behesht. N‑acetylcysteine prevents hypothyroidism‑induced impairment of learning and memory in adolescent male rats via affecting oxidative status, inflammatory response and BDNF in hippocampal tissues. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087834. |
n‑acetylcysteine prevents hypothyroidism‑induced impairment of learning and memory in adolescent male rats via affecting oxidative status, inflammatory response and bdnf in hippocampal tissues. |
2024-08-01 |
2024-08-03 |
rat |
Amir Basiri, Saeid Izadi, Samaneh Kakhki, Vida Alikahni, Saeedeh Askarian, Farimah Behesht. N‑acetylcysteine prevents hypothyroidism‑induced impairment of learning and memory in adolescent male rats via affecting oxidative status, inflammatory response and BDNF in hippocampal tissues. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087834. |
in biochemical results, ac reduced both malondialdehyde content and nitrite while increased the thiol content, catalase and superoxide dismutase enzymes activity in both the cortex and the hippocampus, and a notable improvement in brain‑derived neurotrophic factor (bdnf) levels in hippocampal tissues of the hypothyroid rats, while decreasing the level of interleukin‑6 in rat hippocampal region. |
2024-08-01 |
2024-08-03 |
rat |
Mahmoud Hosseini, Fatemeh Seyedi, Mahdiyeh Hedayati-Moghadam, Mohammad Ali-Hassanzadeh, Hedyeh Askarpour, Somaieh Mansouri, Hadi Shafieemojaz, Yousef Baghchegh. The effects of PPARγ agonists on long‑termpotentiation and apoptosis in the hippocampusarea of juvenile hypothyroid rats. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087839. |
the aim of the present study was to evaluate the effect of rosiglitazone (rsg) or pioglitazone (pog) on the synaptic plasticity, neuronal apoptosis, brain-derived neurotrophic factor (bdnf), and nitric oxide (no) metabolites in the hippocampus of juvenile hypothyroid rats. |
2024-08-01 |
2024-08-03 |
rat |
Mahmoud Hosseini, Fatemeh Seyedi, Mahdiyeh Hedayati-Moghadam, Mohammad Ali-Hassanzadeh, Hedyeh Askarpour, Somaieh Mansouri, Hadi Shafieemojaz, Yousef Baghchegh. The effects of PPARγ agonists on long‑termpotentiation and apoptosis in the hippocampusarea of juvenile hypothyroid rats. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087839. |
then, the hippocampal tissues were collected to determine bdnf and no levels and the degree of apoptosis. |
2024-08-01 |
2024-08-03 |
rat |
Mahmoud Hosseini, Fatemeh Seyedi, Mahdiyeh Hedayati-Moghadam, Mohammad Ali-Hassanzadeh, Hedyeh Askarpour, Somaieh Mansouri, Hadi Shafieemojaz, Yousef Baghchegh. The effects of PPARγ agonists on long‑termpotentiation and apoptosis in the hippocampusarea of juvenile hypothyroid rats. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087839. |
this study's results revealed that pog or rsg normalized ltp impairment, neuronal apoptosis, and improved bdnf content in the hippocampal tissue of juvenile hypothyroid rats. |
2024-08-01 |
2024-08-03 |
rat |
Denisse Paredes, David A Morila. Therapeutic effects of extinction require hippocampal input and BDNF signaling in IL. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-07-31. PMID:39085427. |
therapeutic effects of extinction require hippocampal input and bdnf signaling in il. |
2024-07-31 |
2024-08-03 |
Not clear |
Sonia Melgar-Locatelli, M Carmen Mañas-Padilla, Adriana Castro-Zavala, Patricia Rivera, María Del Carmen Razola-Díaz, Francisco J Monje, Celia Rodríguez-Pérez, Estela Castilla-Orteg. Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory. Food & function. 2024-07-29. PMID:39069830. |
adult hippocampal neurogenesis and brain-derived neurotrophic factor (bdnf) expression in the hippocampus and prefrontal cortex were evaluated using immunohistochemistry and western blot. |
2024-07-29 |
2024-08-02 |
mouse |
Sonia Melgar-Locatelli, M Carmen Mañas-Padilla, Adriana Castro-Zavala, Patricia Rivera, María Del Carmen Razola-Díaz, Francisco J Monje, Celia Rodríguez-Pérez, Estela Castilla-Orteg. Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory. Food & function. 2024-07-29. PMID:39069830. |
however, both cocoa-enriched diets increased immobility in the forced swimming test and hippocampal bdnf expression. |
2024-07-29 |
2024-08-02 |
mouse |
Vartika Gupta, S Prasa. Differential Alterations in the Expression of AMPA Receptor and Its Trafficking Proteins in the Hippocampus Are Associated with Recognition Memory Impairment in the Rotenone-Parkinson's Disease Mouse Model: Neuroprotective Role of Bacopa monnieri Extract CDRI 08. Molecular neurobiology. 2024-07-29. PMID:39073529. |
our results also reveal that the above alterations in the hippocampus are associated with similar expression patterns of total creb, pcreb, and bdnf. |
2024-07-29 |
2024-08-02 |
mouse |
Parisa Habibi, Siamak Shahidi, Maryam Khajvand-Abedini, Zahra Shahabi, Nasser Ahmadiasl, Mohammad Reza Alipour, Mahdi Ramezani, Alireza Komak. Effect of Young Plasma Therapy on Cognition, Oxidative Stress, miRNA-134, BDNF, CREB, and SIRT-1 Expressions and Neuronal Survey in the Hippocampus of Aged Ovariectomized Rats with Alzheimer's. Brain sciences. vol 14. issue 7. 2024-07-27. PMID:39061398. |
effect of young plasma therapy on cognition, oxidative stress, mirna-134, bdnf, creb, and sirt-1 expressions and neuronal survey in the hippocampus of aged ovariectomized rats with alzheimer's. |
2024-07-27 |
2024-07-29 |
rat |
Ting Zhang, Yu Yue, Chen Li, Xuangao Wu, Sunmin Par. Vagus Nerve Suppression in Ischemic Stroke by Carotid Artery Occlusion: Implications for Metabolic Regulation, Cognitive Function, and Gut Microbiome in a Gerbil Model. International journal of molecular sciences. vol 25. issue 14. 2024-07-27. PMID:39063072. |
ao and vgx increased the neuronal cell death and neurological severity scores associated with increased hippocampal lipid profiles and lipid peroxidation, as well as changes in the inflammatory cytokine expression and brain-derived neurotrophic factor (bdnf) levels. |
2024-07-27 |
2024-07-29 |
Not clear |
Hajar Abkhezr, Shirin Babri, Mahsa Farid-Habibi, Fereshteh Farajdokht, Saeed Sadigh-Eteghad, Gisou Mohadde. Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring. Iranian journal of basic medical sciences. vol 27. issue 9. 2024-07-26. PMID:39055879. |
effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum bdnf levels in male adult rat offspring. |
2024-07-26 |
2024-07-28 |
rat |
Hajar Abkhezr, Shirin Babri, Mahsa Farid-Habibi, Fereshteh Farajdokht, Saeed Sadigh-Eteghad, Gisou Mohadde. Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring. Iranian journal of basic medical sciences. vol 27. issue 9. 2024-07-26. PMID:39055879. |
this study aimed to determine the effect of ps and extremely low-frequency electromagnetic field (elf-emf) on spatial memory, serum corticosterone, brain-derived neurotrophic factor (bdnf) concentrations, and hippocampal bdnf levels in adult male offspring. |
2024-07-26 |
2024-07-28 |
rat |