| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ludmila S Inozemtseva, Ksenia A Yatsenko, Natalya Yu Glazova, Andrey A Kamensky, Nikolai F Myasoedov, Natalia G Levitskaya, Igor A Grivennikov, Oleg V Doloto. Antidepressant-Like and Antistress Effects of the ACTH(4-10) Synthetic Analogs Semax and Melanotan II on Male Rats in a Model of Chronic Unpredictable Stress. European journal of pharmacology. 2024-10-23. PMID:39442746. |
our findings show that in the cus paradigm, systemically administered acth(4-10) analogs semax and mtii exert antidepressant-like effects on anhedonia and hippocampal bdnf levels, and attenuate markers of chronic stress load, at least in male rats. |
2024-10-23 |
2024-10-26 |
rat |
| b' Salih Erdem, Hale Sayan \\xc3\\x96za\\xc3\\xa7mak, \\xc4\\xb0nci Turan, Meryem Ergen\\xc3\\xa. The protective effect of angiotensin II type I receptor blocker (valsartan) on behavioral impairment, NLRP3, BDNF, and oxidative stress in the brain tissue of ovariectomized female rats. Physiological reports. vol 12. issue 20. 2024-10-23. PMID:39443283.' |
levels of oxidative stress markers, nlrp3, il-1β, bdnf, and creb were analyzed in the hippocampus and prefrontal cortex tissues. |
2024-10-23 |
2024-10-26 |
rat |
| b' Salih Erdem, Hale Sayan \\xc3\\x96za\\xc3\\xa7mak, \\xc4\\xb0nci Turan, Meryem Ergen\\xc3\\xa. The protective effect of angiotensin II type I receptor blocker (valsartan) on behavioral impairment, NLRP3, BDNF, and oxidative stress in the brain tissue of ovariectomized female rats. Physiological reports. vol 12. issue 20. 2024-10-23. PMID:39443283.' |
in the hippocampus of ovx rats, oxidative stress (p < 0.01), nlrp3 (p < 0.05), and il-1β (p < 0.01) levels were elevated, whereas bdnf levels were significantly decreased (p < 0.01). |
2024-10-23 |
2024-10-26 |
rat |
| b' Salih Erdem, Hale Sayan \\xc3\\x96za\\xc3\\xa7mak, \\xc4\\xb0nci Turan, Meryem Ergen\\xc3\\xa. The protective effect of angiotensin II type I receptor blocker (valsartan) on behavioral impairment, NLRP3, BDNF, and oxidative stress in the brain tissue of ovariectomized female rats. Physiological reports. vol 12. issue 20. 2024-10-23. PMID:39443283.' |
in conclusion, at1rb has a therapeutic effect on menopause-induced depression and anxiety-like behaviors, likely by reducing oxidative stress and increasing bdnf production in the hippocampus. |
2024-10-23 |
2024-10-26 |
rat |
| Liu Tao, Chuanjie Yao, Sijie Wang, Yuying Ye, Zhengchao Tu, Xiaojian Jiang, Lipeng Xu, Luchen Shan, Zheng Liu, Pei Y. Synthesis and biological evaluation of novel isobenzofuran-1(3H)-one derivatives as antidepressant agents. Bioorganic & medicinal chemistry. vol 114. 2024-10-21. PMID:39432939. |
thirdly, compound 10a was further investigated and found to enhance crs-induced hippocampal neuron damage recovery and elevate the expression of synaptic-associated proteins such as bdnf, trkb, psd95, and spinophilin in crs-induced mice. |
2024-10-21 |
2024-10-24 |
mouse |
| Fengjiao Liu, Yaxin Jia, Liwei Zhao, Li-Na Xiao, Xizhen Cheng, Yingying Xiao, Ying Zhang, Yuling Zhang, Huimin Yu, Qiao-En Deng, Yuanyuan Zhang, Yimeng Feng, Junfang Wang, Yonggang Gao, Xuan Zhang, Yunyun Gen. Escin ameliorates CUMS-induced depressive-like behavior via BDNF/TrkB/CREB and TLR4/MyD88/NF-κB signaling pathways in rats. European journal of pharmacology. 2024-10-19. PMID:39426465. |
pathological changes in the hippocampal regions were identified through nissl staining, and western blotting was used to quantify the protein levels of bdnf, trkb, creb, tlr4, myd88, and nf-κb. |
2024-10-19 |
2024-10-22 |
rat |
| Nastaran Talaee, Mehrnaz Azad Yekta, Salar Vasegh. New insights into individual differences in response to chronic unpredictable mild stress (CUMS) in rats with respect to hippocampal BDNF and GSK3-β expression levels. Physiology & behavior. 2024-10-19. PMID:39426694. |
new insights into individual differences in response to chronic unpredictable mild stress (cums) in rats with respect to hippocampal bdnf and gsk3-β expression levels. |
2024-10-19 |
2024-10-22 |
rat |
| Nastaran Talaee, Mehrnaz Azad Yekta, Salar Vasegh. New insights into individual differences in response to chronic unpredictable mild stress (CUMS) in rats with respect to hippocampal BDNF and GSK3-β expression levels. Physiology & behavior. 2024-10-19. PMID:39426694. |
the present study aimed to evaluate potential individual differences in response to cums in rats, with respect to the expression level of brain-derived neurotrophic factor (bdnf) and glycogen synthase kinases 3-beta (gsk3-β) (proteins involved in the modulation of mood, neuroplasticity, and cognition) in the hippocampus. |
2024-10-19 |
2024-10-22 |
rat |
| Takuma Kitamoto, Takafumi Mizushige, Xiaonan Xie, Taisei Uematsu, Risako Ogura, Kakeru Sato, Yuki Yamazaki, Tsubasa Matsushita, Hiroshi Hasegaw. Antistress Effects of Terpinen-4-ol and Compounds of Mimicked Yuzu Synthetic Fragrance in Humans and Mice. Foods (Basel, Switzerland). vol 13. issue 19. 2024-10-16. PMID:39410087. |
in the forced swim test conducted in experiment 2, sd significantly reduced immobility time, and increased the expression of neurotrophic factors bdnf, ngf, and nt-3 in the hippocampus of mice. |
2024-10-16 |
2024-10-18 |
mouse |
| Nur Akman Alacabey, Devran Coşkun, Ahmet Ateşşahi. Effects of Boron on Learning and Behavioral Disorders in Rat Autism Model Induced by Intracerebroventricular Propionic Acid. Biological trace element research. 2024-10-13. PMID:39397138. |
proinflammatory cytokines (tumor necrosis factor alpha (tnf-α), interleukin 1 beta (il-1β), interleukin 6 (il-6)) and brain-derived neurotrophic factor (bdnf) levels were assessed in the hippocampus. |
2024-10-13 |
2024-10-16 |
rat |
| Soraya Alimohammadi, Gisou Mohaddes, Rana Keyhanmanesh, Seyed Zanyar Athari, Negin Azizifar, Fereshteh Farajdokh. Intranasal AdipoRon mitigates motor and cognitive deficits in hemiparkinsonian rats through neuroprotective mechanisms against oxidative stress and synaptic dysfunction. Neuropharmacology. 2024-10-11. PMID:39393589. |
the hippocampal tissues of the animals were harvested to examine oxidative stress status as well as the protein expressions of brain-derived neurotrophic factor (bdnf) and postsynaptic density protein 95 (psd-95). |
2024-10-11 |
2024-10-14 |
rat |
| Soraya Alimohammadi, Gisou Mohaddes, Rana Keyhanmanesh, Seyed Zanyar Athari, Negin Azizifar, Fereshteh Farajdokh. Intranasal AdipoRon mitigates motor and cognitive deficits in hemiparkinsonian rats through neuroprotective mechanisms against oxidative stress and synaptic dysfunction. Neuropharmacology. 2024-10-11. PMID:39393589. |
furthermore, we found that unilateral 6-ohda injection elevated hippocampal oxidative stress (ros) while concurrently reducing total antioxidant capacity (tac), bdnf, psd-95, and antioxidant enzymes (sod, gpx). |
2024-10-11 |
2024-10-14 |
rat |
| Soraya Alimohammadi, Gisou Mohaddes, Rana Keyhanmanesh, Seyed Zanyar Athari, Negin Azizifar, Fereshteh Farajdokh. Intranasal AdipoRon mitigates motor and cognitive deficits in hemiparkinsonian rats through neuroprotective mechanisms against oxidative stress and synaptic dysfunction. Neuropharmacology. 2024-10-11. PMID:39393589. |
chronic intranasal adipo ameliorated spatial and recognition memory deterioration in hemiparkinsonian rats, presumably by increasing hippocampal synaptic protein levels, reducing oxidative stress, and increasing bdnf. |
2024-10-11 |
2024-10-14 |
rat |
| Kelly N Brice, Paige N Braden-Kuhle, Shelby K Miller, Allison Regan, Vivienne Lacy, Michael J Chumley, Gary W Boeh. Chronic sleep loss alters the inflammatory response and BDNF expression in C57BL/6J mice. Journal of neuroimmunology. vol 396. 2024-10-08. PMID:39378741. |
the current research investigated the impact of chronic sleep restriction (csr) on inflammatory markers and hippocampal bdnf mrna, following an immune insult in both male and female mice. |
2024-10-08 |
2024-10-11 |
mouse |
| Kelly N Brice, Paige N Braden-Kuhle, Shelby K Miller, Allison Regan, Vivienne Lacy, Michael J Chumley, Gary W Boeh. Chronic sleep loss alters the inflammatory response and BDNF expression in C57BL/6J mice. Journal of neuroimmunology. vol 396. 2024-10-08. PMID:39378741. |
further, csr led to suppressed hippocampal bdnf expression in males, an effect not observed in females. |
2024-10-08 |
2024-10-11 |
mouse |
| Ali Mohammadkhanizadeh, Yasaman Hosseini, Farnaz Nikbakht, Mohammadreza Parvizi, Fatemeh Khodabandehlo. Evaluating the potential effects of apigenin on memory, anxiety, and social interaction amelioration after social isolation stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-10-05. PMID:39367711. |
the oxidative stress markers, il-6, and bdnf levels were measured in the hippocampus. |
2024-10-05 |
2024-10-07 |
rat |
| Ali Mohammadkhanizadeh, Yasaman Hosseini, Farnaz Nikbakht, Mohammadreza Parvizi, Fatemeh Khodabandehlo. Evaluating the potential effects of apigenin on memory, anxiety, and social interaction amelioration after social isolation stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-10-05. PMID:39367711. |
in addition, si stress increased hippocampal levels of il-6 and malondialdehyde (mda) content, whereas it reduced the hippocampal bdnf level and superoxide dismutase (sod) activities. |
2024-10-05 |
2024-10-07 |
rat |
| Ali Mohammadkhanizadeh, Yasaman Hosseini, Farnaz Nikbakht, Mohammadreza Parvizi, Fatemeh Khodabandehlo. Evaluating the potential effects of apigenin on memory, anxiety, and social interaction amelioration after social isolation stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-10-05. PMID:39367711. |
these desirable effects of api might be related to amelioration in the bdnf level, il-6, and oxidative stress biomarkers in the hippocampus. |
2024-10-05 |
2024-10-07 |
rat |
| Nevine Fathy, Merna A Labib, Reham M Essam, Noha A El-Boghdad. The Interplay between MiR-134/BDNF and LKB1/AMPK/SIRT1 Accentuates the Antidepressant Efficacy of Empagliflozin in Ovariectomized Rats. ACS chemical neuroscience. 2024-10-01. PMID:39350330. |
moreover, empa curtailed ovx-induced alterations of serum estradiol, hippocampal serotonin, mir-134 expression, as well as bdnf. |
2024-10-01 |
2024-10-03 |
rat |
| M Windy McNerney, Eric P Kraybill, Sindhu Narayanan, Fatemeh S Mojabi, Vaibhavi Venkataramanan, Alesha Heat. Memory-related hippocampal brain-derived neurotrophic factor activation pathways from repetitive transcranial magnetic stimulation in the 3xTg-AD mouse line. Experimental gerontology. vol 183. 2024-10-01. PMID:39351497. |
the current study aimed to expand these findings by measuring brain-derived neurotrophic factor (bdnf), its downstream hippocampal signaling molecules, and behavioral effects of rtms on the 3xtg-ad mouse line. |
2024-10-01 |
2024-10-03 |
mouse |