| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Shi, Jie Yang, Ying Liu, Huan Zhao, Man Li, Dongdong Yang, Quan Xi. Huanglian Wendan Decoction Improves Insomnia in Rats by Regulating BDNF/TrkB Signaling Pathway Through Gut Microbiota-Mediated SCFAs and Affecting Microglia Polarization. Molecular neurobiology. 2024-07-02. PMID:38954253. |
in addition, hwd increased the expression levels of bdnf and trkb in the hippocampus. |
2024-07-02 |
2024-07-06 |
rat |
| Kenichi Oga, Manabu Fuchikami, Hironori Kobayashi, Tatsuhiro Miyagi, Sho Fujita, Satoshi Fujita, Satoshi Okada, Shigeru Morinob. Involvement of dysregulated hippocampal histone H3K9 methylation at the promoter of the BDNF gene in impaired memory extinction. Psychopharmacology. 2024-06-28. PMID:38940908. |
involvement of dysregulated hippocampal histone h3k9 methylation at the promoter of the bdnf gene in impaired memory extinction. |
2024-06-28 |
2024-06-30 |
Not clear |
| Mehmet Alkanat, Hafize Özdemir Alkana. D-Limonene reduces depression-like behaviour and enhances learning and memory through an anti-neuroinflammatory mechanism in male rats subjected to chronic restraint stress. The European journal of neuroscience. 2024-06-27. PMID:38932560. |
the levels of bdnf, il-1β, il-6 and caspase-1 were measured from hippocampal tissue using the elisa method. |
2024-06-27 |
2024-06-29 |
rat |
| Ji-Yun Kang, Jin-Seok Lee, Jing-Hua Wang, Chang-Gue So. Sleep deprivation in adolescent mice impairs long-term memory till early adulthood via suppression of hippocampal astrocytes. Sleep. 2024-06-27. PMID:38934552. |
furthermore, the hippocampal region exhibited significantly diminished protein expressions of astrocyte, characterized by lowered levels of aquaporin 4 (aqp4), a representative molecule involved in brain clearance processes, and reduced protein expressions of brain-derived neurotrophic factor (bdnf). |
2024-06-27 |
2024-06-29 |
mouse |
| b' Merve Deniz De\\xc4\\x9firmenci, Hasan \\xc3\\x87al\\xc4\\xb1\\xc5\\x9fkan, Emel G\\xc3\\xbcne\\xc5\\x9. Effects of chronic intermittent cold stress on anxiety-depression-like behaviors in adolescent rats. Behavioural brain research. 2024-06-27. PMID:38936426.' |
cold stress resulted in decreased bdnf levels in the prefrontal cortex and striatum (p < 0.05), increased cortisol levels in the prefrontal cortex (p < 0.05), increased il-1β levels in the hippocampus and thalamus (p < 0.05), increased protein carbonyl levels in the striatum (p < 0.05), and decreased tas in the prefrontal cortex and thalamus (p < 0.05). |
2024-06-27 |
2024-06-30 |
human |
| Eman Thabet, Abeer E Dief, Shams A-F Arafa, Dalia Yakout, Mennatallah A Al. Antibiotic-induced gut microbe dysbiosis alters neurobehavior in mice through modulation of BDNF and gut integrity. Physiology & behavior. 2024-06-26. PMID:38925433. |
we tested exploratory behavior, anxiety, memory, depression-like behavior, and hippocampal and frontal lobe bdnf protein level alterations in response to antibiotics and its downstream effect on the pi3k/akt1/bcl2 pathway. |
2024-06-26 |
2024-06-29 |
mouse |
| D K Avrova, L V Bayunova, N F Avrova, I O Zakharov. The Effect of Intranasal Administration of Gangliosides on the Viability of CA1 Hippocampal Neurons in Rat Two-Vessel Occlusion Model of Forebrain Ischemia/Reperfusion Injury. Bulletin of experimental biology and medicine. 2024-06-21. PMID:38907060. |
the expression of neurotrophic factor bdnf in the ca1 region of hippocampus did not differ in sham-operated rats and animals exposed to ischemia/reperfusion. |
2024-06-21 |
2024-06-24 |
rat |
| Xiaoyu Wang, Qian Pang, Jiangqi Hu, Bin Luo, Yunping Lu, Xu Sun, Shixiang Meng, Qingsong Jian. Cognitive decline in Sprague-Dawley rats induced by neuroplasticity changes after occlusal support loss. CNS neuroscience & therapeutics. vol 30. issue 6. 2024-06-20. PMID:38898731. |
the most well-known function of the hippocampus is learning and memory, and the mechanism behind is neuroplasticity, which strongly depends on the level of brain-derived neurotrophic factor (bdnf). |
2024-06-20 |
2024-06-22 |
rat |
| Jéssica Rabelo Bezerra, Tyciane de Souza Nascimento, Juliete Tavares, Mayara Sandrielly Soares de Aguiar, Maiara Virgínia Viana Maia, Geanne Matos de Andrad. Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin. Molecular neurobiology. 2024-06-19. PMID:38898198. |
icv-stz induced a reduction in viable cells, depletion of bdnf, and triggered astrogliosis and microgliosis in the cortex and hippocampus. |
2024-06-19 |
2024-06-22 |
mouse |
| Jéssica Rabelo Bezerra, Tyciane de Souza Nascimento, Juliete Tavares, Mayara Sandrielly Soares de Aguiar, Maiara Virgínia Viana Maia, Geanne Matos de Andrad. Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin. Molecular neurobiology. 2024-06-19. PMID:38898198. |
additionally, it prevented bdnf depletion in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions), and mitigated astrogliosis and microgliosis in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions). |
2024-06-19 |
2024-06-22 |
mouse |
| Mira Hamze, Cathy Brier, Emmanuelle Buhler, Jinwei Zhang, Igor Medina, Christophe Porche. Regulation of Neuronal Chloride Homeostasis by Pro- and Mature Brain-Derived Neurotrophic Factor (BDNF) via KCC2 Cation-Chloride Cotransporters in Rat Cortical Neurons. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892438. |
we investigated the interplay between both forms of bdnf and chloride homeostasis in rat hippocampal neurons and in utero electroporated cortices of rat pups, spanning the behavioral, cellular, and molecular levels. |
2024-06-19 |
2024-06-21 |
rat |
| Changjian Wan, Lulu Shi, Yuying Lai, Zhuhong Wu, Mingzhe Zou, Zhibin Liu, Wei Meng, Songhua Wan. Long-term voluntary running improves cognitive ability in developing mice by modulating the cholinergic system, antioxidant ability, and BDNF/PI3K/Akt/CREB pathway. Neuroscience letters. 2024-06-18. PMID:38889879. |
additionally, exercise also upregulated the expression of brain-derived neurotrophic factor (bdnf), tropomyosin receptor kinase b (trkb), phosphoinositide 3 kinases (pi3k), akt, camp response element-binding protein (creb), and phosphorylated camp response element-binding protein (p-creb) in the hippocampus. |
2024-06-18 |
2024-06-21 |
mouse |
| Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. |
this study aims to determine the effect of chronic meth administration on the expression of bdnf protein using immunohistochemistry in the rat frontal cortex and hippocampus. |
2024-06-17 |
2024-06-21 |
rat |
| Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. |
the results showed that hippocampal ca1 bdnf protein was significantly increased by 72 % above control values in the ed-binge rats, while other hippocampal regions and frontal cortex were not significantly affected. |
2024-06-17 |
2024-06-21 |
rat |
| Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. |
the hippocampal bdnf increase may reflect an initial increase in a protective factor produced in response to elevated glutamate release resulting in neurodegenerative excitotoxicity. |
2024-06-17 |
2024-06-21 |
rat |
| Shiyan Zhang, Boya Gu, Kai Zhen, Liwen Du, Yuanyuan Lv, Laikang Y. Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis. Archives of gerontology and geriatrics. vol 126. 2024-06-15. PMID:38878598. |
in addition, exercise significantly increased bdnf levels in the hippocampus (smd = 0.92, p< 0.00001) and cortex (smd = 1.56, p= 0.02) of ad models. |
2024-06-15 |
2024-06-18 |
Not clear |
| Shiyan Zhang, Boya Gu, Kai Zhen, Liwen Du, Yuanyuan Lv, Laikang Y. Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis. Archives of gerontology and geriatrics. vol 126. 2024-06-15. PMID:38878598. |
exercise, especially treadmill exercise, swimming, and voluntary wheel running, significantly increased bdnf levels in hippocampus and cortex of ad models, with swimming being the most effective intervention type. |
2024-06-15 |
2024-06-18 |
Not clear |
| Caíque Olegário Diniz E Magalhães, Ricardo Augusto Leoni De Sousa, Bruno Ferreira Mendes, Isabela Rocha Dias, Ramona Ramalho Souza Pereira, Gabriela Cruz Pereira, Kil Sun Lee, Marco Fabricio Dias Peixoto, Ricardo Cardoso Cassilha. Accumulated HIIT inhibits anxiety and depression, improves cognitive function, and memory-related proteins in the hippocampus of aged rats. Experimental brain research. 2024-06-12. PMID:38864869. |
rats were euthanized, and the hippocampus was harvested for western blot analyses (camkii and bdnf). |
2024-06-12 |
2024-06-14 |
rat |
| Ashrakt H Abdelhamid, Eman M Mantawy, Riham S Said, Ebtehal El-Demerdas. Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway. Toxicology and applied pharmacology. 2024-06-10. PMID:38857790. |
furthermore, saxa boosted hippocampal neurogenesis by upregulating brain-derived neurotrophic factor (bdnf) expression. |
2024-06-10 |
2024-06-14 |
rat |
| Ayman Alzu'bi, Ejlal Abu-El-Rub, Fatimah Almahasneh, Lena Tahat, Rabaa Y Athamneh, Ramada Khasawneh, Hiba Alzoubi, Doaa S Ghorab, Rawan Almazari, Mazhar Salim Al Zoubi, Raed M Al-Zoub. Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice. Neurotoxicology. vol 103. 2024-06-08. PMID:38823587. |
these findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (bdnf), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. |
2024-06-08 |
2024-06-11 |
mouse |