| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Noêmia Martins de Lima, Juliana Presti-Torres, Gustavo Vedana, Luisa Azambuja Alcalde, Laura Stertz, Gabriel Rodrigo Fries, Rafael Roesler, Monica Levy Andersen, João Quevedo, Flávio Kapczinski, Nadja Schröde. Early life stress decreases hippocampal BDNF content and exacerbates recognition memory deficits induced by repeated D-amphetamine exposure. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21645554. |
early life stress decreases hippocampal bdnf content and exacerbates recognition memory deficits induced by repeated d-amphetamine exposure. |
2011-11-21 |
2023-08-12 |
rat |
| Maria Noêmia Martins de Lima, Juliana Presti-Torres, Gustavo Vedana, Luisa Azambuja Alcalde, Laura Stertz, Gabriel Rodrigo Fries, Rafael Roesler, Monica Levy Andersen, João Quevedo, Flávio Kapczinski, Nadja Schröde. Early life stress decreases hippocampal BDNF content and exacerbates recognition memory deficits induced by repeated D-amphetamine exposure. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21645554. |
bdnf levels were decreased in the hippocampus of d+sal rats. |
2011-11-21 |
2023-08-12 |
rat |
| Samina Salim, Mohammad Asghar, Manish Taneja, Iiris Hovatta, Gaurav Chugh, Craig Vollert, Anthony V. Potential contribution of oxidative stress and inflammation to anxiety and hypertension. Brain research. vol 1404. 2011-11-21. PMID:21704983. |
here, we report that sub-chronic induction of oxidative stress via pharmacological induction leads to i) reduction in glyoxalase (glo)-1 and glutathione reductase (gsr)-1 expression; ii) calpain mediated reduction of brain derived neurotrophic factor (bdnf) levels; iii) nfκb mediated upregulation of proinflammatory factors interleukin (il)-6 and tumor necrosis factor (tnf)-α and elevated angiotensin (at)-1 receptor levels in hippocampus, amygdala and locus coeruleus regions of the brain. |
2011-11-21 |
2023-08-12 |
rat |
| Zhe Xiong, Bo Jiang, Peng-Fei Wu, Jia Tian, Liang-Liang Shi, Jun Gu, Zhuang-Li Hu, Hui Fu, Fang Wang, Jian-Guo Che. Antidepressant effects of a plant-derived flavonoid baicalein involving extracellular signal-regulated kinases cascade. Biological & pharmaceutical bulletin. vol 34. issue 2. 2011-11-15. PMID:21415537. |
furthermore, it was shown that bai reversed the reduction of extracellular erks phosphorylation and the level of bdnf expression in the hippocampus of cms model rats. |
2011-11-15 |
2023-08-12 |
mouse |
| Kimihiko Watanabe, Eri Hashimoto, Wataru Ukai, Takao Ishii, Toshihiro Yoshinaga, Takafumi Ono, Masaru Tateno, Ippei Watanabe, Tomohiro Shirasaka, Satoshi Saito, Toshikazu Sait. Effect of antidepressants on brain-derived neurotrophic factor (BDNF) release from platelets in the rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 8. 2011-11-14. PMID:20708057. |
in addition, bdnf may promote neurogenesis and protect against hippocampal volume loss in depressive disorders. |
2011-11-14 |
2023-08-12 |
human |
| Kai-Ren Luo, Chen-Jee Hong, Ying-Jay Liou, Sheue-Jane Hou, Yn-Ho Huang, Shih-Jen Tsa. Differential regulation of neurotrophin S100B and BDNF in two rat models of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 8. 2011-11-14. PMID:20728493. |
we measured bdnf and s100b protein levels in the serum, prefrontal cortex, striatum and hippocampus of rats in models of depression, i.e., olfactory bulbectomy (obx) and chronic unpredictable stress (cus) models. |
2011-11-14 |
2023-08-12 |
rat |
| Kai-Ren Luo, Chen-Jee Hong, Ying-Jay Liou, Sheue-Jane Hou, Yn-Ho Huang, Shih-Jen Tsa. Differential regulation of neurotrophin S100B and BDNF in two rat models of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 8. 2011-11-14. PMID:20728493. |
serum bdnf levels were significantly increased in the obx rats, as were hippocampal bdnf levels in the cus rats, in comparison with their respective controls. |
2011-11-14 |
2023-08-12 |
rat |
| Araceli Martínez-Moreno, Luis F Rodríguez-Durán, Martha L Escoba. Late Protein Synthesis-Dependent Phases in CTA Long-Term Memory: BDNF Requirement. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:21960964. |
studies in the rat hippocampus have been shown that bdnf is capable to rescue the late-phase of long-term potentiation as well as the hippocampus-related ltm when protein synthesis was inhibited. |
2011-11-10 |
2023-08-12 |
rat |
| Patrick S Murray, Philip V Holme. An overview of brain-derived neurotrophic factor and implications for excitotoxic vulnerability in the hippocampus. International journal of peptides. vol 2011. 2011-11-10. PMID:21966294. |
the paper focuses on literature describing the role of bdnf in hippocampal development and neuroplasticity. |
2011-11-10 |
2023-08-12 |
Not clear |
| Patrick S Murray, Philip V Holme. An overview of brain-derived neurotrophic factor and implications for excitotoxic vulnerability in the hippocampus. International journal of peptides. vol 2011. 2011-11-10. PMID:21966294. |
bdnf expression is highly sensitive to developmental and environmental factors, and increased bdnf signaling enhances neurogenesis, neurite sprouting, electrophysiological activity, and other processes reflective of a general enhancement of hippocampal function. |
2011-11-10 |
2023-08-12 |
Not clear |
| Patrick S Murray, Philip V Holme. An overview of brain-derived neurotrophic factor and implications for excitotoxic vulnerability in the hippocampus. International journal of peptides. vol 2011. 2011-11-10. PMID:21966294. |
however, the increased activity also comes at a cost: bdnf plasticity renders the hippocampus more vulnerable to hyperexcitability and/or excitotoxic damage. |
2011-11-10 |
2023-08-12 |
Not clear |
| Patrick S Murray, Philip V Holme. An overview of brain-derived neurotrophic factor and implications for excitotoxic vulnerability in the hippocampus. International journal of peptides. vol 2011. 2011-11-10. PMID:21966294. |
exercise dramatically increases hippocampal bdnf levels and produces behavioral effects consistent with this phenomenon. |
2011-11-10 |
2023-08-12 |
Not clear |
| Caroline M Coppens, Taweeporn Siripornmongcolchai, Karin Wibrand, Maria Nordheim Alme, Bauke Buwalda, Sietse F de Boer, Jaap M Koolhaas, Clive R Bramha. Social Defeat during Adolescence and Adulthood Differentially Induce BDNF-Regulated Immediate Early Genes. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:22065953. |
we show that social defeat during adolescence and adulthood differentially regulates expression of the immediate early genes bdnf, arc, carp, and tieg1, as measured by qpcr in tissue lysates from prefrontal cortex, nucleus accumbens, and hippocampus. |
2011-11-10 |
2023-08-12 |
human |
| Jucélia J Fortunato, Gislaine Z Réus, Tamires R Kirsch, Roberto B Stringari, Gabriel R Fries, Flávio Kapczinski, Jaime E Hallak, Antônio W Zuardi, José A Crippa, João Queved. Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 10. 2011-11-09. PMID:20686906. |
chronic administration of harmine elicits antidepressant-like effects and increases bdnf levels in rat hippocampus. |
2011-11-09 |
2023-08-12 |
rat |
| Jucélia J Fortunato, Gislaine Z Réus, Tamires R Kirsch, Roberto B Stringari, Gabriel R Fries, Flávio Kapczinski, Jaime E Hallak, Antônio W Zuardi, José A Crippa, João Queved. Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 10. 2011-11-09. PMID:20686906. |
brain-derived neurotrophic factor (bdnf) hippocampal levels were assessed in imipramine and harmine-treated rats by elisa sandwich assay. |
2011-11-09 |
2023-08-12 |
rat |
| Jucélia J Fortunato, Gislaine Z Réus, Tamires R Kirsch, Roberto B Stringari, Gabriel R Fries, Flávio Kapczinski, Jaime E Hallak, Antônio W Zuardi, José A Crippa, João Queved. Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 10. 2011-11-09. PMID:20686906. |
interestingly, chronic administration of harmine at the higher doses (10 and 15 mg/kg), but not imipramine, increased bdnf protein levels in rat hippocampus. |
2011-11-09 |
2023-08-12 |
rat |
| Aurélie Blugeot, Cyril Rivat, Elodie Bouvier, Jenny Molet, Amandine Mouchard, Brigitte Zeau, Christophe Bernard, Jean-Jacques Benoliel, Chrystel Becke. Vulnerability to depression: from brain neuroplasticity to identification of biomarkers. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 36. 2011-10-31. PMID:21900567. |
in contrast, 42% of animals displayed persistent decreased serum and hippocampus bdnf concentrations, reduced hippocampal volume and neurogenesis, ca3 dendritic retraction and decrease in spine density, as well as amygdala neuron hypertrophy, constituting latent vulnerability traits to depression. |
2011-10-31 |
2023-08-12 |
Not clear |
| Hiroyuki Mizoguchi, Junya Nakade, Masaki Tachibana, Daisuke Ibi, Eiichi Someya, Hiroyuki Koike, Hiroyuki Kamei, Toshitaka Nabeshima, Shigeyoshi Itohara, Kazuhiro Takuma, Makoto Sawada, Jun Sato, Kiyofumi Yamad. Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 36. 2011-10-31. PMID:21900575. |
matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-bdnf to mature bdnf in the hippocampus. |
2011-10-31 |
2023-08-12 |
mouse |
| Hiroyuki Mizoguchi, Junya Nakade, Masaki Tachibana, Daisuke Ibi, Eiichi Someya, Hiroyuki Koike, Hiroyuki Kamei, Toshitaka Nabeshima, Shigeyoshi Itohara, Kazuhiro Takuma, Makoto Sawada, Jun Sato, Kiyofumi Yamad. Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 36. 2011-10-31. PMID:21900575. |
these findings suggest that mmp-9 is involved in the progression of behavioral phenotypes in kindled mice because of conversion of pro-bdnf to mature bdnf in the hippocampus. |
2011-10-31 |
2023-08-12 |
mouse |
| Chelsey Hannah-Poquette, Grant W Anderson, Shlomit Flaisher-Grinberg, Jia Wang, Tonya M Meinerding, Haim Eina. Modeling mania: Further validation for Black Swiss mice as model animals. Behavioural brain research. vol 223. issue 1. 2011-10-18. PMID:21570428. |
β-catenin and bdnf expression were evaluated in the frontal cortex and hippocampus of untreated bs, cba/j, a/j and c57bl/6 mice by western blot. |
2011-10-18 |
2023-08-12 |
mouse |