| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flurin Cathomas, Christian Vogler, Jessica C Euler-Sigmund, Dominique J-F de Quervain, Andreas Papassotiropoulo. Fine-mapping of the brain-derived neurotrophic factor (BDNF) gene supports an association of the Val66Met polymorphism with episodic memory. The international journal of neuropsychopharmacology. vol 13. issue 8. 2011-12-19. PMID:20482942. |
brain-derived neurotrophic factor (bdnf) plays an important role in hippocampal synaptic plasticity and long-term potentiation. |
2011-12-19 |
2023-08-12 |
Not clear |
| Xindao Hu, Lauren Ballo, Lauren Pietila, Chris Viesselmann, Jason Ballweg, Derek Lumbard, Matt Stevenson, Elliott Merriam, Erik W Den. BDNF-induced increase of PSD-95 in dendritic spines requires dynamic microtubule invasions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 43. 2011-12-19. PMID:22031905. |
here we demonstrate in mouse hippocampal neurons that mt entries into spines regulate the increase in postsynaptic density-95 (psd-95) protein after brain-derived neurotrophic factor (bdnf) treatment. |
2011-12-19 |
2023-08-12 |
mouse |
| Elaheh Nooshinfar, Alireza Akbarzadeh-Baghban, Esmail Meisam. Effects of increasing durations of immobilization stress on plasma corticosterone level, learning and memory and hippocampal BDNF gene expression in rats. Neuroscience letters. vol 500. issue 1. 2011-12-14. PMID:21683767. |
effects of increasing durations of immobilization stress on plasma corticosterone level, learning and memory and hippocampal bdnf gene expression in rats. |
2011-12-14 |
2023-08-12 |
rat |
| Elaheh Nooshinfar, Alireza Akbarzadeh-Baghban, Esmail Meisam. Effects of increasing durations of immobilization stress on plasma corticosterone level, learning and memory and hippocampal BDNF gene expression in rats. Neuroscience letters. vol 500. issue 1. 2011-12-14. PMID:21683767. |
learning and memory was measured using passive avoidance testing (stl=step-through-latency scores) as well as plasma corticosterone (cst) levels and hippocampal bdnf gene expression. |
2011-12-14 |
2023-08-12 |
rat |
| Elaheh Nooshinfar, Alireza Akbarzadeh-Baghban, Esmail Meisam. Effects of increasing durations of immobilization stress on plasma corticosterone level, learning and memory and hippocampal BDNF gene expression in rats. Neuroscience letters. vol 500. issue 1. 2011-12-14. PMID:21683767. |
hippocampal bdnf gene expression increased in the 1-h and 3-h stressed groups (44%, p<0.05 and 71%, p<0.01); but this parameter steadily declined in the 5-h stressed group (26%, p<0.05) and weeklong stressed group (6%, not significant). |
2011-12-14 |
2023-08-12 |
rat |
| Elaheh Nooshinfar, Alireza Akbarzadeh-Baghban, Esmail Meisam. Effects of increasing durations of immobilization stress on plasma corticosterone level, learning and memory and hippocampal BDNF gene expression in rats. Neuroscience letters. vol 500. issue 1. 2011-12-14. PMID:21683767. |
statistical analysis revealed an apparent but significant negative correlation between changes in memory and those of bdnf gene expression, indicating that bdnf may possibly play a compensatory role, reversing deleterious effects of stress on hippocampal memory functions. |
2011-12-14 |
2023-08-12 |
rat |
| Kang Zheng, Juan Ji An, Feng Yang, Weifeng Xu, Zhi-Qing David Xu, Jianyoung Wu, Tomas G M Hökfelt, André Fisahn, Baoji Xu, Bai L. TrkB signaling in parvalbumin-positive interneurons is critical for gamma-band network synchronization in hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 41. 2011-12-13. PMID:21949401. |
using mutant mice (trkb-pv(-/-)) in which the gene for the bdnf receptor, tyrosine kinase b receptor (trkb), has been specifically deleted in parvalbumin-expressing, fast-spiking gabaergic (pv+) interneurons, we show that trkb is structurally and functionally important for the integrity of the hippocampal network. |
2011-12-13 |
2023-08-12 |
mouse |
| Weihong Yan, Ting Zhang, Weiping Jia, Xiaojiang Sun, Xueyuan Li. Chronic stress impairs learning and hippocampal cell proliferation in senescence-accelerated prone mice. Neuroscience letters. vol 490. issue 2. 2011-12-12. PMID:21184809. |
in this study, we examined the effects of chronic restraint stress (crs) on learning in the y-maze, hippocampal cell proliferation, and the expression of brain-derived neurotrophic factor (bdnf) in the hippocampus of 4-month-old samp8 and samr1. |
2011-12-12 |
2023-08-12 |
mouse |
| Weihong Yan, Ting Zhang, Weiping Jia, Xiaojiang Sun, Xueyuan Li. Chronic stress impairs learning and hippocampal cell proliferation in senescence-accelerated prone mice. Neuroscience letters. vol 490. issue 2. 2011-12-12. PMID:21184809. |
furthermore, crs significantly decreased the expression of bdnf protein and mrna in the hippocampus of samp8 and samr1. |
2011-12-12 |
2023-08-12 |
mouse |
| Weihong Yan, Ting Zhang, Weiping Jia, Xiaojiang Sun, Xueyuan Li. Chronic stress impairs learning and hippocampal cell proliferation in senescence-accelerated prone mice. Neuroscience letters. vol 490. issue 2. 2011-12-12. PMID:21184809. |
in addition, our findings suggested a role of bdnf in the stress-induced impairment of learning and hippocampal cell proliferation in both strains. |
2011-12-12 |
2023-08-12 |
mouse |
| Russell W Brown, Daniel M Noel, Jessica J Smith, Meredith L Smith, Kimberly N Huggins, Katalin Szebeni, Attila Szebeni, Michelle Duffourc, Michelle Chandley, Gregory A Ordwa. Eszopiclone facilitation of the antidepressant efficacy of fluoxetine using a social defeat stress model. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21699914. |
beta adrenoreceptors, brain-derived neurotrophic factor (bdnf) and camp response element binding protein (creb) expression in the hippocampus and frontal cortex were also analyzed. |
2011-12-09 |
2023-08-12 |
mouse |
| Hiroshi Komatsu, Arihisa Ohara, Kazumasu Sasaki, Hiromi Abe, Hisaki Hattori, F Scott Hall, George R Uhl, Ichiro Sor. Decreased response to social defeat stress in μ-opioid-receptor knockout mice. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21703297. |
these results suggest that the μ-opioid receptor is involved in the behavioral sequelae of psychosocial stress and consequent regulation of bdnf expression in the hippocampus, and may play an important role in psychiatric disorders for which stress is an important predisposing or precipitating factor, such as depression, posttraumatic stress disorder, and social anxiety disorder. |
2011-12-09 |
2023-08-12 |
mouse |
| S M Lasley, M E Gilber. Developmental thyroid hormone insufficiency reduces expression of brain-derived neurotrophic factor (BDNF) in adults but not in neonates. Neurotoxicology and teratology. vol 33. issue 4. 2011-12-05. PMID:21530650. |
the present study examined the impact of modest levels of developmental thyroid hormone insufficiency on bdnf protein expression in the hippocampus, cortex and cerebellum in the neonatal and adult offspring of rat dams treated throughout pregnancy and lactation. |
2011-12-05 |
2023-08-12 |
rat |
| S M Lasley, M E Gilber. Developmental thyroid hormone insufficiency reduces expression of brain-derived neurotrophic factor (BDNF) in adults but not in neonates. Neurotoxicology and teratology. vol 33. issue 4. 2011-12-05. PMID:21530650. |
hippocampus, cortex, and cerebellum were separated from dissected brains and assessed for bdnf protein. |
2011-12-05 |
2023-08-12 |
rat |
| S M Lasley, M E Gilber. Developmental thyroid hormone insufficiency reduces expression of brain-derived neurotrophic factor (BDNF) in adults but not in neonates. Neurotoxicology and teratology. vol 33. issue 4. 2011-12-05. PMID:21530650. |
males were more affected by ptu than females, bdnf levels in hippocampus and cortex were altered but not those in cerebellum, and biphasic dose-response functions were detected in both sexes. |
2011-12-05 |
2023-08-12 |
rat |
| Il-Sun Kwon, Jee-Yin Ah. p48 Ebp1 acts as a downstream mediator of Trk signaling in neurons, contributing neuronal differentiation. Neurochemistry international. vol 58. issue 2. 2011-11-23. PMID:21145366. |
the p48 protein acts as a downstream effector of the trk receptor, which mediates the functions of nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) in hippocampal cells. |
2011-11-23 |
2023-08-12 |
Not clear |
| Verna Louhivuori, Annalisa Vicario, Marko Uutela, Tomi Rantamäki, Lauri M Louhivuori, Eero Castrén, Enrico Tongiorgi, Karl E Akerman, Maija L Castré. BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse. Neurobiology of disease. vol 41. issue 2. 2011-11-22. PMID:21047554. |
pilocarpine-induced seizures caused an accumulation of bdnf mrna transcripts in the most proximal segments of dendrites in cortical but not in hippocampal neurons of fmr1-ko mice. |
2011-11-22 |
2023-08-12 |
mouse |
| Verna Louhivuori, Annalisa Vicario, Marko Uutela, Tomi Rantamäki, Lauri M Louhivuori, Eero Castrén, Enrico Tongiorgi, Karl E Akerman, Maija L Castré. BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse. Neurobiology of disease. vol 41. issue 2. 2011-11-22. PMID:21047554. |
in addition, bdnf protein levels were increased in the hippocampus but reduced in the cortex of fmr1-ko mice in line with regional differences of synaptic plasticity in the brain of fmr1-ko mice. |
2011-11-22 |
2023-08-12 |
mouse |
| Cristina Benatti, Silvia Alboni, Claudia Montanari, Federica Caggia, Fabio Tascedda, Nicoletta Brunello, Joan M C Blo. Central effects of a local inflammation in three commonly used mouse strains with a different anxious phenotype. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21624397. |
we then measured intra-strain differences and cfa-induced inter-strain effects on the expression of various genes with a recognized role in pain and anxiety: bdnf, il-6, il-1β, il-18 and nmda receptor subunits in the mouse thalamus, hippocampus and hypothalamus. |
2011-11-21 |
2023-08-12 |
mouse |
| Cristina Benatti, Silvia Alboni, Claudia Montanari, Federica Caggia, Fabio Tascedda, Nicoletta Brunello, Joan M C Blo. Central effects of a local inflammation in three commonly used mouse strains with a different anxious phenotype. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21624397. |
the more anxious phenotype observed in b6c3f1 hybrid mice displayed lower levels of bdnf mrna in the hippocampus and hypothalamus when compared to outbred cd1 and c57bl/6j inbred mice. |
2011-11-21 |
2023-08-12 |
mouse |