| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clarissa S Gama, Lara Canever, Bruna Panizzutti, Carolina Gubert, Laura Stertz, Raffael Massuda, Mariana Pedrini, David F de Lucena, Renata D Luca, Daiane B Fraga, Alexandra S Heylmann, Pedro F Deroza, Alexandra I Zugn. Effects of omega-3 dietary supplement in prevention of positive, negative and cognitive symptoms: a study in adolescent rats with ketamine-induced model of schizophrenia. Schizophrenia research. vol 141. issue 2-3. 2013-03-19. PMID:22954755. |
prefrontal-cortex, hippocampus and striatum tissues were extracted right after behavioral tasks for mrna bdnf expression analysis. |
2013-03-19 |
2023-08-12 |
rat |
| Clarissa S Gama, Lara Canever, Bruna Panizzutti, Carolina Gubert, Laura Stertz, Raffael Massuda, Mariana Pedrini, David F de Lucena, Renata D Luca, Daiane B Fraga, Alexandra S Heylmann, Pedro F Deroza, Alexandra I Zugn. Effects of omega-3 dietary supplement in prevention of positive, negative and cognitive symptoms: a study in adolescent rats with ketamine-induced model of schizophrenia. Schizophrenia research. vol 141. issue 2-3. 2013-03-19. PMID:22954755. |
there was no difference between groups in prefrontal-cortex, hippocampus and striatum for mrna bdnf expression. |
2013-03-19 |
2023-08-12 |
rat |
| Joseph P Kambeitz, Sagnik Bhattacharyya, Lana M Kambeitz-Ilankovic, Isabel Valli, David A Collier, Philip McGuir. Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis. Neuroscience and biobehavioral reviews. vol 36. issue 9. 2013-03-14. PMID:22813992. |
variation in the bdnf gene, particularly the rs6265 (val(66)met) single nucleotide polymorphism (snp), has been linked to variability in human memory performance and to both the structure and physiological response of the hippocampus, which plays a central role in memory processing. |
2013-03-14 |
2023-08-12 |
human |
| Joseph P Kambeitz, Sagnik Bhattacharyya, Lana M Kambeitz-Ilankovic, Isabel Valli, David A Collier, Philip McGuir. Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis. Neuroscience and biobehavioral reviews. vol 36. issue 9. 2013-03-14. PMID:22813992. |
employing a meta-analytic approach, we examined the effect of the bdnf val(66)met polymorphism on human memory (5922 subjects) and hippocampal structure (2985 subjects) and physiology (362 subjects). |
2013-03-14 |
2023-08-12 |
human |
| Joseph P Kambeitz, Sagnik Bhattacharyya, Lana M Kambeitz-Ilankovic, Isabel Valli, David A Collier, Philip McGuir. Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis. Neuroscience and biobehavioral reviews. vol 36. issue 9. 2013-03-14. PMID:22813992. |
our results suggest that variations in the rs6265 snp of the bdnf gene have a significant effect on memory performance, and on both the structure and physiology of the hippocampus, with carriers of the met allele being adversely affected. |
2013-03-14 |
2023-08-12 |
human |
| Zhao-Hui Zhang, Li-Na Wu, Jing-Gui Song, Wen-Qiang L. Correlations between cognitive impairment and brain‑derived neurotrophic factor expression in the hippocampus of post-stroke depression rats. Molecular medicine reports. vol 6. issue 4. 2013-03-14. PMID:22842820. |
real‑time pcr and immunohistochemical methods were used to detect changes in bdnf mrna and protein expression in the hippocampus. |
2013-03-14 |
2023-08-12 |
rat |
| Zhao-Hui Zhang, Li-Na Wu, Jing-Gui Song, Wen-Qiang L. Correlations between cognitive impairment and brain‑derived neurotrophic factor expression in the hippocampus of post-stroke depression rats. Molecular medicine reports. vol 6. issue 4. 2013-03-14. PMID:22842820. |
bdnf expression in the hippocampus was significantly lower in the psd and depression groups compared with that in the normal control group (p<0.01). |
2013-03-14 |
2023-08-12 |
rat |
| Zhao-Hui Zhang, Li-Na Wu, Jing-Gui Song, Wen-Qiang L. Correlations between cognitive impairment and brain‑derived neurotrophic factor expression in the hippocampus of post-stroke depression rats. Molecular medicine reports. vol 6. issue 4. 2013-03-14. PMID:22842820. |
the decrease in bdnf expression in the hippocampus of psd rats may aggravate cognitive impairment, however, the degree of cognitive impairment cannot be reflected by the expression levels of bdnf in the hippocampus. |
2013-03-14 |
2023-08-12 |
rat |
| I Baranowska-Bosiacka, L Strużyńska, I Gutowska, A Machalińska, A Kolasa, P Kłos, G A Czapski, M Kurzawski, A Prokopowicz, M Marchlewicz, K Safranow, B Machaliński, B Wiszniewska, D Chlube. Perinatal exposure to lead induces morphological, ultrastructural and molecular alterations in the hippocampus. Toxicology. vol 303. 2013-03-07. PMID:23146751. |
this treatment protocol resulted in a concentration of pb in rat offspring whole blood (pb-b) below the threshold of 10 μg/dl, considered safe for humans.we studied casp-3 activity and expression, aif nuclear translocation, dna fragmentation, as well as bax, bcl-2 mrna and protein expression as well as bdnf concentration in selected structures of the rat brain: forebrain cortex (fc), cerebellum (c) and hippocampus (h). |
2013-03-07 |
2023-08-12 |
rat |
| M L Molendijk, M-J van Tol, B W J H Penninx, N J A van der Wee, A Aleman, D J Veltman, P Spinhoven, B M Elzing. BDNF val66met affects hippocampal volume and emotion-related hippocampal memory activity. Translational psychiatry. vol 2. 2013-03-04. PMID:22832736. |
bdnf val66met affects hippocampal volume and emotion-related hippocampal memory activity. |
2013-03-04 |
2023-08-12 |
human |
| M L Molendijk, M-J van Tol, B W J H Penninx, N J A van der Wee, A Aleman, D J Veltman, P Spinhoven, B M Elzing. BDNF val66met affects hippocampal volume and emotion-related hippocampal memory activity. Translational psychiatry. vol 2. 2013-03-04. PMID:22832736. |
the val(66)met polymorphism on the bdnf gene has been reported to explain individual differences in hippocampal volume and memory-related activity. |
2013-03-04 |
2023-08-12 |
human |
| M L Molendijk, M-J van Tol, B W J H Penninx, N J A van der Wee, A Aleman, D J Veltman, P Spinhoven, B M Elzing. BDNF val66met affects hippocampal volume and emotion-related hippocampal memory activity. Translational psychiatry. vol 2. 2013-03-04. PMID:22832736. |
in conclusion, bdnf val(66)met has a significant impact on hippocampal volume independently of childhood abuse and psychiatric status. |
2013-03-04 |
2023-08-12 |
human |
| H Y Tan, A G Chen, Q Chen, L B Browne, B Verchinski, B Kolachana, F Zhang, J Apud, J H Callicott, V S Mattay, D R Weinberge. Epistatic interactions of AKT1 on human medial temporal lobe biology and pharmacogenetic implications. Molecular psychiatry. vol 17. issue 10. 2013-02-27. PMID:21788944. |
further, supporting akt1's role in transducing hippocampal neuroplasticity and dopaminergic processes, we found epistasis with functional polymorphisms in bdnf and comt--genes also implicated in mtl biology related to akt1. |
2013-02-27 |
2023-08-12 |
human |
| Zeeba D Kabir, Frederico Lourenco, Maureen E Byrne, Aaron Katzman, Francis Lee, Anjali M Rajadhyaksha, Barry E Kosofsk. Brain-derived neurotrophic factor genotype impacts the prenatal cocaine-induced mouse phenotype. Developmental neuroscience. vol 34. issue 2-3. 2013-02-22. PMID:22572518. |
prenatal cocaine exposure leads to persistent alterations in the growth factor brain-derived neurotrophic factor (bdnf), particularly in the medial prefrontal cortex (mpfc) and hippocampus, brain regions important in cognitive functioning. |
2013-02-22 |
2023-08-12 |
mouse |
| Zeeba D Kabir, Frederico Lourenco, Maureen E Byrne, Aaron Katzman, Francis Lee, Anjali M Rajadhyaksha, Barry E Kosofsk. Brain-derived neurotrophic factor genotype impacts the prenatal cocaine-induced mouse phenotype. Developmental neuroscience. vol 34. issue 2-3. 2013-02-22. PMID:22572518. |
in contrast, in the hippocampus of prenatally saline- and cocaine-treated adult val66met mice, there were significantly lower levels of mature bdnf protein compared to val66val mice. |
2013-02-22 |
2023-08-12 |
mouse |
| Qun Wang, Yong Lin, Qiang Zhang, Si-Qing Sun, Xue-Feng Lin. [Changes of BDNF expression in hippocampus and serum of rats with artificial chronic obstructive pulmonary disease]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 6. 2013-02-21. PMID:22193444. |
[changes of bdnf expression in hippocampus and serum of rats with artificial chronic obstructive pulmonary disease]. |
2013-02-21 |
2023-08-12 |
rat |
| Qun Wang, Yong Lin, Qiang Zhang, Si-Qing Sun, Xue-Feng Lin. [Changes of BDNF expression in hippocampus and serum of rats with artificial chronic obstructive pulmonary disease]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 6. 2013-02-21. PMID:22193444. |
and the expression of bdnf in the hippocampus was assessed using the immunohistochemistry and image analysis. |
2013-02-21 |
2023-08-12 |
rat |
| Qun Wang, Yong Lin, Qiang Zhang, Si-Qing Sun, Xue-Feng Lin. [Changes of BDNF expression in hippocampus and serum of rats with artificial chronic obstructive pulmonary disease]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 6. 2013-02-21. PMID:22193444. |
the results showed that bdnf in the hippocampus and serum significantly increased in the smoking, lps and smoking + lps groups, compared to that in the control group. |
2013-02-21 |
2023-08-12 |
rat |
| Qun Wang, Yong Lin, Qiang Zhang, Si-Qing Sun, Xue-Feng Lin. [Changes of BDNF expression in hippocampus and serum of rats with artificial chronic obstructive pulmonary disease]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 6. 2013-02-21. PMID:22193444. |
however, the expression of bdnf was less in the smoking + lps group than that in the smoking or lps group both in the hippocampus and serum. |
2013-02-21 |
2023-08-12 |
rat |
| Qun Wang, Yong Lin, Qiang Zhang, Si-Qing Sun, Xue-Feng Lin. [Changes of BDNF expression in hippocampus and serum of rats with artificial chronic obstructive pulmonary disease]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 6. 2013-02-21. PMID:22193444. |
in conclusion, the expression of bdnf in the hippocampus and serum is highly increased in the copd group. |
2013-02-21 |
2023-08-12 |
rat |