| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
collectively, these results demonstrated that xiangshao granule could effectively induce antidepressive effects in the depression mouse model by ameliorating the expression of hippocampal bdnf and trkb. |
2013-12-24 |
2023-08-12 |
mouse |
| G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu, H T Nguyen, V Nicolas, G Auregan, I David, A Dranovsky, P Hantraye, R Hen, A M Gardier, N Déglon, B P Guiar. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational psychiatry. vol 3. 2013-12-23. PMID:23632457. |
bdnf overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. |
2013-12-23 |
2023-08-12 |
mouse |
| G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu, H T Nguyen, V Nicolas, G Auregan, I David, A Dranovsky, P Hantraye, R Hen, A M Gardier, N Déglon, B P Guiar. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational psychiatry. vol 3. 2013-12-23. PMID:23632457. |
at nerve terminal such as the hippocampus, the enhancement of 5-ht availability increases brain-derived neurotrophic factor (bdnf) synthesis and signaling, a major event in the stimulation of adult neurogenesis. |
2013-12-23 |
2023-08-12 |
mouse |
| G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu, H T Nguyen, V Nicolas, G Auregan, I David, A Dranovsky, P Hantraye, R Hen, A M Gardier, N Déglon, B P Guiar. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational psychiatry. vol 3. 2013-12-23. PMID:23632457. |
our results indicate that bdnf overexpression in hippocampal astrocytes produced anxiolytic-/antidepressant-like activity in the novelty suppressed feeding in relation with the stimulation of hippocampal neurogenesis whereas it did not potentiate the effects of the ssri fluoxetine on these parameters. |
2013-12-23 |
2023-08-12 |
mouse |
| G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu, H T Nguyen, V Nicolas, G Auregan, I David, A Dranovsky, P Hantraye, R Hen, A M Gardier, N Déglon, B P Guiar. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational psychiatry. vol 3. 2013-12-23. PMID:23632457. |
these results emphasize an original role of hippocampal astrocytes in the synthesis of bdnf, which can act through neurogenesis-dependent and -independent mechanisms to regulate different facets of anxiolytic-like responses. |
2013-12-23 |
2023-08-12 |
mouse |
| Peifang Jiang, Tao Zhu, Wenting Zhao, Jue Shen, Yonglin Yu, Jialu Xu, Xi Chen, Huimin Y. The persistent effects of maternal infection on the offspring's cognitive performance and rates of hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 44. 2013-12-18. PMID:23562668. |
maternal infection significantly increased the number of proliferating cells in the offspring's hippocampus at postnatal 3, 7 and 14 days, accompanied by significantly increased expressions of bdnf, trkb and p-akt at postnatal 3 and 7 days. |
2013-12-18 |
2023-08-12 |
rat |
| Peifang Jiang, Tao Zhu, Wenting Zhao, Jue Shen, Yonglin Yu, Jialu Xu, Xi Chen, Huimin Y. The persistent effects of maternal infection on the offspring's cognitive performance and rates of hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 44. 2013-12-18. PMID:23562668. |
on postnatal 28 days, maternal infection did not significantly affect the neuronal and glial differentiation, nor any significant changes in the expression levels of bdnf and trkb in the hippocampus. |
2013-12-18 |
2023-08-12 |
rat |
| Kazuko Sakata, Joshua R Mastin, Sean M Duke, Meghan G Vail, Abigail E Overacre, Brittany E Dong, Shanker Jh. Effects of antidepressant treatment on mice lacking brain-derived neurotrophic factor expression through promoter IV. The European journal of neuroscience. vol 37. issue 11. 2013-12-12. PMID:23406189. |
we tested our hypothesis that deficits caused by promoter iv deficiency (depression-like behavior, decreased levels of bdnf, and neurogenesis in the hippocampus) could be rescued by a 3-week treatment with different types of antidepressants: fluoxetine, phenelzine, duloxetine, or imipramine. |
2013-12-12 |
2023-08-12 |
mouse |
| Kazuko Sakata, Joshua R Mastin, Sean M Duke, Meghan G Vail, Abigail E Overacre, Brittany E Dong, Shanker Jh. Effects of antidepressant treatment on mice lacking brain-derived neurotrophic factor expression through promoter IV. The European journal of neuroscience. vol 37. issue 11. 2013-12-12. PMID:23406189. |
our results indicate that the behavioral effects in the tail suspension test by antidepressants do not require promoter iv-driven bdnf expression and occur without a detectable increase in hippocampal bdnf levels and neurogenesis but may involve increased dendritic reorganisation of immature neurons. |
2013-12-12 |
2023-08-12 |
mouse |
| Kazuko Sakata, Joshua R Mastin, Sean M Duke, Meghan G Vail, Abigail E Overacre, Brittany E Dong, Shanker Jh. Effects of antidepressant treatment on mice lacking brain-derived neurotrophic factor expression through promoter IV. The European journal of neuroscience. vol 37. issue 11. 2013-12-12. PMID:23406189. |
in conclusion, the antidepressant treatment demonstrated limited efficacy; it partially reversed the defective phenotypes caused by promoter iv deficiency but not hippocampal bdnf levels. |
2013-12-12 |
2023-08-12 |
mouse |
| Christina P Furtado, Kate E Hoy, Jerome J Maller, Greg Savage, Zafiris J Daskalakis, Paul B Fitzgeral. An investigation of medial temporal lobe changes and cognition following antidepressant response: a prospective rTMS study. Brain stimulation. vol 6. issue 3. 2013-12-11. PMID:22784443. |
extensive preclinical literature suggests that hippocampal volume reductions from mdd induced suppression of adult neurogenesis can be reversed by different types of classical antidepressant treatments which increase expression of bdnf. |
2013-12-11 |
2023-08-12 |
Not clear |
| Hai Thi Do, Céline Bruelle, Timofey Tselykh, Pilvi Jalonen, Laura Korhonen, Dan Lindhol. Reciprocal regulation of very low density lipoprotein receptors (VLDLRs) in neurons by brain-derived neurotrophic factor (BDNF) and Reelin: involvement of the E3 ligase Mylip/Idol. The Journal of biological chemistry. vol 288. issue 41. 2013-12-11. PMID:23990472. |
we show here that bdnf increased the levels of the reelin receptor (vldl receptor (vldlr)) in hippocampal neurons by increasing gene expression. |
2013-12-11 |
2023-08-12 |
Not clear |
| Lorena S Navigatore-Fonzo, Rebeca L Golini, Ivana T Ponce, Silvia M Delgado, Maria G Plateo-Pignatari, María S Gimenez, Ana C Anzulovic. Retinoic acid receptors move in time with the clock in the hippocampus. Effect of a vitamin-A-deficient diet. The Journal of nutritional biochemistry. vol 24. issue 5. 2013-12-10. PMID:22902328. |
previously, we showed that vitamin a deficiency modifies clock bmal1 and per1 as well as bdnf and neurogranin daily rhythmicity in the rat hippocampus when animals are maintained under 12-h-light:12-h-dark conditions. |
2013-12-10 |
2023-08-12 |
rat |
| Kazuko Sakata, Keri Martinowich, Newton H Woo, Robert J Schloesser, Dennisse V Jimenez, Yuanyuan Ji, Liya Shen, Bai L. Role of activity-dependent BDNF expression in hippocampal-prefrontal cortical regulation of behavioral perseverance. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 37. 2013-12-10. PMID:23980178. |
here, we show that disruption of activity-dependent bdnf expression impairs bdnf-dependent late-phase long-term potentiation (l-ltp) in ca1, a site of hippocampal output to the pfc. |
2013-12-10 |
2023-08-12 |
mouse |
| Kazuko Sakata, Keri Martinowich, Newton H Woo, Robert J Schloesser, Dennisse V Jimenez, Yuanyuan Ji, Liya Shen, Bai L. Role of activity-dependent BDNF expression in hippocampal-prefrontal cortical regulation of behavioral perseverance. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 37. 2013-12-10. PMID:23980178. |
thus, activity-dependent bdnf expression in the hippocampus and pfc may contribute to cognitive and behavioral flexibility. |
2013-12-10 |
2023-08-12 |
mouse |
| Keiko Kuwatsuka, Hiromi Hayashi, Yuka Onoue, Ikuko Miyazaki, Toshihiro Koyama, Masato Asanuma, Yoshihisa Kitamura, Toshiaki Send. The mechanisms of electroconvulsive stimuli in BrdU-positive cells of the dentate gyrus in ACTH-treated rats. Journal of pharmacological sciences. vol 122. issue 1. 2013-12-06. PMID:23615225. |
the present study was undertaken to further characterize the mechanism of treatmentresistant antidepressant effects of electroconvulsive stimuli by measuring cell proliferation, brain-derived neurotrophic factor (bdnf) levels, and phosphorylated and total cyclic adenosine monophosphate (camp) response element-binding protein (pcreb/creb) levels in the hippocampus of acth-treated rats. |
2013-12-06 |
2023-08-12 |
rat |
| Hao Feng, Li-Min Lu, Ying Huang, Yi-Chun Zhu, Tai Ya. [Blockade of NMDA receptor enhances corticosterone-induced downregulation of brain-derived neurotrophic factor gene expression in the rat hippocampus through cAMP response element binding protein pathway]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 5. 2013-12-05. PMID:16220190. |
because of the importance of brain-derived neurotrophic factor (bdnf) in the functions of the hippocampal neurons, alteration of the expression of bdnf is thought to be involved in the corticosterone effect on the hippocampus. |
2013-12-05 |
2023-08-12 |
rat |
| Hao Feng, Li-Min Lu, Ying Huang, Yi-Chun Zhu, Tai Ya. [Blockade of NMDA receptor enhances corticosterone-induced downregulation of brain-derived neurotrophic factor gene expression in the rat hippocampus through cAMP response element binding protein pathway]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 5. 2013-12-05. PMID:16220190. |
to determine whether change in bdnf in the hippocampus is involved in the corticosterone effect, we injected corticosterone (2 mg/kg, s.c.) to sprague-dawley rats and measured the mrna, probdnf and mature bdnf protein levels in the hippocampus. |
2013-12-05 |
2023-08-12 |
rat |
| Hao Feng, Li-Min Lu, Ying Huang, Yi-Chun Zhu, Tai Ya. [Blockade of NMDA receptor enhances corticosterone-induced downregulation of brain-derived neurotrophic factor gene expression in the rat hippocampus through cAMP response element binding protein pathway]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 5. 2013-12-05. PMID:16220190. |
mk801 promoted the downregulation of bdnf gene expression in the rat hippocampus by corticosterone. |
2013-12-05 |
2023-08-12 |
rat |
| Hao Feng, Li-Min Lu, Ying Huang, Yi-Chun Zhu, Tai Ya. [Blockade of NMDA receptor enhances corticosterone-induced downregulation of brain-derived neurotrophic factor gene expression in the rat hippocampus through cAMP response element binding protein pathway]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 5. 2013-12-05. PMID:16220190. |
taken together, our results indicate that corticosterone downregulates bdnf gene expression in the rat hippocampus through creb pathway and that blockade of nmda receptor enhances this effect of corticosterone in reducing bdnf expression. |
2013-12-05 |
2023-08-12 |
rat |