| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tatiana Barichello, Lutiana R Simões, Samira S Valvassori, Jaqueline S Generoso, Paulo Eduardo D V Aveline, Diogo Dominguini, Samuel G Elias, Marcia C Vilela, João Quevedo, Antonio Lucio Teixeir. Klebsiella pneumoniae meningitis induces memory impairment and increases pro-inflammatory host response in the central nervous system of Wistar rats. Journal of medical microbiology. vol 63. issue Pt 1. 2014-02-17. PMID:24105840. |
the hippocampus, frontal cortex and cerebrospinal fluid were isolated to determine the cytokine, chemokine and brain-derived neurotrophic factor (bdnf) levels. |
2014-02-17 |
2023-08-12 |
rat |
| Lin Chen, Jianguo Dai, Zhongli Wang, Huiyu Zhang, Yufang Huang, Yunan Zha. Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3 β -CREB Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-02-13. PMID:24523822. |
results of experiment 1 revealed that gts (50 and 25 mg kg(-1) d(-1)) exhibited antidepressant activity and not statistically altered hippocampal protein levels of brain-derived neurotrophic factor (bdnf) and neurofilament light chain (nf-l). |
2014-02-13 |
2023-08-12 |
mouse |
| Lin Chen, Jianguo Dai, Zhongli Wang, Huiyu Zhang, Yufang Huang, Yunan Zha. Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3 β -CREB Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-02-13. PMID:24523822. |
the gts treatments reversed the corticosterone-induced changes in mrna levels of bdnf and nf-l, and protein levels of bdnf nf-l, phosphor-camp response element-binding protein (ser133), and phosphor-glycogen synthase kinase-3 β (ser9) in the hippocampus. |
2014-02-13 |
2023-08-12 |
mouse |
| Clarissa M Comim, Bruna P Mendonça, Diogo Dominguini, Andreza L Cipriano, Amanda V Steckert, Giselli Scaini, Mariz Vainzof, Emílio L Streck, Felipe Dal-Pizzol, João Queved. Central nervous system involvement in the animal model of myodystrophy. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23508358. |
in summary, it was observed that homozygous mice presented impairment to the habituation and avoidance memory tasks; low levels of brain-derived neurotrophic factor (bdnf) in the prefrontal cortex, hippocampus, cortex and cerebellum; increased lipid peroxidation in the prefrontal cortex, hippocampus, striatum, and cerebellum; an increase of protein peroxidation in the prefrontal cortex, hippocampus, striatum, cerebellum, and cortex; a decrease of complex i activity in the prefrontal cortex and cerebellum; a decrease of complex ii activity in the prefrontal cortex and cerebellum; a decrease of complex iv activity in the prefrontal cortex and cerebellum; an increase in the cortex; and an increase of creatine kinase activity in the striatum and cerebellum. |
2014-02-12 |
2023-08-12 |
mouse |
| Yuhui Sun, Jane Evans, Bruce Russell, Rob Kydd, Bronwen Conno. A benzodiazepine impairs the neurogenic and behavioural effects of fluoxetine in a rodent model of chronic stress. Neuropharmacology. vol 72. 2014-02-11. PMID:23639432. |
this was parallelled by reduced bdnf levels in the hippocampus. |
2014-02-11 |
2023-08-12 |
Not clear |
| Han Wei, Guanghua Wu, Jinglou Chen, Xuenong Zhang, Chaomei Xiong, Yongfang Lei, Wei Chen, Jinlan Rua. (2S)-5, 2', 5'-trihydroxy-7-methoxyflavanone, a natural product from Abacopteris penangiana, presents neuroprotective effects in vitro and in vivo. Neurochemical research. vol 38. issue 8. 2014-02-06. PMID:23670091. |
biochemical analysis revealed that tmf inhibited the activation of ap-1 (activator protein-1) and upregulated the level of bdnf (brain derived neurophic factor) as well as the ratio of gsh/gssg in the hippocampus of d-gal treated mice. |
2014-02-06 |
2023-08-12 |
mouse |
| Sahar Moghbelinejad, Marjan Nassiri-Asl, Taghi Naserpour Farivar, Esmail Abbasi, Mehdi Sheikhi, Mina Taghiloo, Farzaneh Farsad, Amir Samimi, Farid Hajial. Rutin activates the MAPK pathway and BDNF gene expression on beta-amyloid induced neurotoxicity in rats. Toxicology letters. vol 224. issue 1. 2014-02-06. PMID:24148604. |
in comparison to the control group, rutin significantly increased extracellular signal-regulated protein kinase 1 (erk1), camp response element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) gene expression in the hippocampus of rats. |
2014-02-06 |
2023-08-12 |
human |
| Dekel Taliaz, Vini Nagaraj, Sharon Haramati, Alon Chen, Abraham Zange. Altered brain-derived neurotrophic factor expression in the ventral tegmental area, but not in the hippocampus, is essential for antidepressant-like effects of electroconvulsive therapy. Biological psychiatry. vol 74. issue 4. 2014-01-30. PMID:22906519. |
interestingly, opposing roles were suggested for bdnf in the hippocampus and the ventral tegmental area (vta), while interactions between these regions were shown on various levels. |
2014-01-30 |
2023-08-12 |
Not clear |
| Dekel Taliaz, Vini Nagaraj, Sharon Haramati, Alon Chen, Abraham Zange. Altered brain-derived neurotrophic factor expression in the ventral tegmental area, but not in the hippocampus, is essential for antidepressant-like effects of electroconvulsive therapy. Biological psychiatry. vol 74. issue 4. 2014-01-30. PMID:22906519. |
here, we evaluated whether bdnf plays an essential role in the antidepressant-like effects of ect and performed a direct comparison between bdnf manipulations in the vta and the hippocampus. |
2014-01-30 |
2023-08-12 |
Not clear |
| Yan Feng Zhen, Jia Zhang, Xing Yu Liu, Hui Fang, Luo Bing Tian, Dong Hao Zhou, Thomas R Kosten, Xiang Yang Zhan. Low BDNF is associated with cognitive deficits in patients with type 2 diabetes. Psychopharmacology. vol 227. issue 1. 2014-01-28. PMID:23263460. |
studies suggest that brain-derived neurotrophic factor (bdnf) plays an essential role in regulating memory-related neuroplasticity in the hippocampus. |
2014-01-28 |
2023-08-12 |
Not clear |
| Laura Psotta, Volkmar Lessmann, Thomas Endre. Impaired fear extinction learning in adult heterozygous BDNF knock-out mice. Neurobiology of learning and memory. vol 103. 2014-01-24. PMID:23578839. |
this deficit in extinction learning is accompanied by a reduction of bdnf protein in the hippocampus, amygdala and the prefrontal cortex. |
2014-01-24 |
2023-08-12 |
mouse |
| Qing-Shan Li, Wei Yang, Yan-Fang Pan, Jie Min, Zhe Zhang, Hui-Zhong Gao, Jin-Shun Q. [Brain-derived neurotrophic factor prevents against amyloid beta protein-induced impairment of hippocampal in vivo long-term potentiation in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 28. issue 5. 2014-01-23. PMID:23252296. |
to explore the effects of brain-derived neurotrophic factor (bdnf) pretreatment on beta amyloid protein (abeta) induced impairment of in vivo hippocampal long-term potentiation (ltp) in the ca1 region of rats. |
2014-01-23 |
2023-08-12 |
rat |
| Min Meng, Xinhan Zhao, Yonghui Dang, Jingyuan Ma, Lixu Li, Shanzhi G. Region-specific expression of brain-derived neurotrophic factor splice variants in morphine conditioned place preference in mice. Brain research. vol 1519. 2014-01-23. PMID:23623815. |
increased expression of bdnf splice variants ii, iv and vi in the hippocampus, caudate putamen (cpu) and nucleus accumbens (nacc). |
2014-01-23 |
2023-08-12 |
mouse |
| Min Meng, Xinhan Zhao, Yonghui Dang, Jingyuan Ma, Lixu Li, Shanzhi G. Region-specific expression of brain-derived neurotrophic factor splice variants in morphine conditioned place preference in mice. Brain research. vol 1519. 2014-01-23. PMID:23623815. |
however, after reinstatement induced by exposure to 6 min of forced swimming (fs), expression of bdnf splice variants ii, iv and vi was increased in the hippocampus, cpu, nacc and prefrontal cortex (pfc). |
2014-01-23 |
2023-08-12 |
mouse |
| Min Meng, Xinhan Zhao, Yonghui Dang, Jingyuan Ma, Lixu Li, Shanzhi G. Region-specific expression of brain-derived neurotrophic factor splice variants in morphine conditioned place preference in mice. Brain research. vol 1519. 2014-01-23. PMID:23623815. |
furthermore, bdnf splice variants ii, iv and vi may play a role in learning and memory for morphine addiction in the hippocampus, cpu and nacc. |
2014-01-23 |
2023-08-12 |
mouse |
| Daiane Engel, Andréa D E Zomkowski, Vicente Lieberknecht, Ana Lúcia Rodrigues, Nelson H Gabila. Chronic administration of duloxetine and mirtazapine downregulates proapoptotic proteins and upregulates neurotrophin gene expression in the hippocampus and cerebral cortex of mice. Journal of psychiatric research. vol 47. issue 6. 2014-01-21. PMID:23522402. |
both duloxetine and mirtazapine produced antidepressant activity in the forced swimming test and induced increased cortical and hippocampal mrna expression of bdnf. |
2014-01-21 |
2023-08-12 |
mouse |
| XiaoDan Yu, Tianhong Ren, XiaoGang Y. Disruption of calmodulin-dependent protein kinase II α/brain-derived neurotrophic factor (α-CaMKII/BDNF) signalling is associated with zinc deficiency-induced impairments in cognitive and synaptic plasticity. The British journal of nutrition. vol 110. issue 12. 2014-01-21. PMID:23823484. |
the present study evaluated whether the impairments caused by gestational and lactational zn deficiency are mediated by the hippocampal calmodulin-dependent protein kinase ii α (α-camkii)/brain-derived neurotrophic factor (bdnf) signalling pathway as well as whether they can be restored by postnatal zn supplementation. |
2014-01-21 |
2023-08-12 |
rat |
| XiaoDan Yu, Tianhong Ren, XiaoGang Y. Disruption of calmodulin-dependent protein kinase II α/brain-derived neurotrophic factor (α-CaMKII/BDNF) signalling is associated with zinc deficiency-induced impairments in cognitive and synaptic plasticity. The British journal of nutrition. vol 110. issue 12. 2014-01-21. PMID:23823484. |
long-term potentiation (ltp) in the rat hippocampal medial perforant path-dentate gyrus pathway was evaluated simultaneously, and α-camkii and bdnf protein levels were examined by western blot analysis. |
2014-01-21 |
2023-08-12 |
rat |
| XiaoDan Yu, Tianhong Ren, XiaoGang Y. Disruption of calmodulin-dependent protein kinase II α/brain-derived neurotrophic factor (α-CaMKII/BDNF) signalling is associated with zinc deficiency-induced impairments in cognitive and synaptic plasticity. The British journal of nutrition. vol 110. issue 12. 2014-01-21. PMID:23823484. |
α-camkii and bdnf protein expression in the hippocampus was significantly reduced in the zd group. |
2014-01-21 |
2023-08-12 |
rat |
| Daiane Biff, Fabrícia Petronilho, Larissa Constantino, Francieli Vuolo, Grettel J Zamora-Berridi, Dhébora Mozena Dall'Igna, Clarissa M Comim, João Quevedo, Flávio Kapczinski, Felipe Dal-Pizzo. Correlation of acute phase inflammatory and oxidative markers with long-term cognitive impairment in sepsis survivors rats. Shock (Augusta, Ga.). vol 40. issue 1. 2014-01-16. PMID:23603768. |
animals were followed until 30 days after surgery and were subjected to the step-down inhibitory avoidance (ia) task, and the hippocampus levels of bdnf were determined. |
2014-01-16 |
2023-08-12 |
rat |