| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daiane Biff, Fabrícia Petronilho, Larissa Constantino, Francieli Vuolo, Grettel J Zamora-Berridi, Dhébora Mozena Dall'Igna, Clarissa M Comim, João Quevedo, Flávio Kapczinski, Felipe Dal-Pizzo. Correlation of acute phase inflammatory and oxidative markers with long-term cognitive impairment in sepsis survivors rats. Shock (Augusta, Ga.). vol 40. issue 1. 2014-01-16. PMID:23603768. |
at 6 h, higher csf levels of thiobarbituric acid-reactive species and tnf-α were observed in septic animals that had a better performance in the ia task and presented higher bdnf levels in the hippocampus. |
2014-01-16 |
2023-08-12 |
rat |
| Daiane Biff, Fabrícia Petronilho, Larissa Constantino, Francieli Vuolo, Grettel J Zamora-Berridi, Dhébora Mozena Dall'Igna, Clarissa M Comim, João Quevedo, Flávio Kapczinski, Felipe Dal-Pizzo. Correlation of acute phase inflammatory and oxidative markers with long-term cognitive impairment in sepsis survivors rats. Shock (Augusta, Ga.). vol 40. issue 1. 2014-01-16. PMID:23603768. |
the persistence of brain inflammation during the acute phase of sepsis is associated with long-term hippocampus levels of bdnf and memory impairment in sepsis survivors. |
2014-01-16 |
2023-08-12 |
rat |
| Sandra Schildt, Thomas Endres, Volkmar Lessmann, Elke Edelman. Acute and chronic interference with BDNF/TrkB-signaling impair LTP selectively at mossy fiber synapses in the CA3 region of mouse hippocampus. Neuropharmacology. vol 71. 2014-01-10. PMID:23587649. |
although bdnf is abundant at hippocampal mossy fiber (mf) synapses, which critically contribute to hippocampus dependent memory, its role in mf synaptic plasticity (long-term potentiation, ltp) remained largely unclear. |
2014-01-10 |
2023-08-12 |
mouse |
| Catarina Rendeiro, David Vauzour, Marcus Rattray, Pierre Waffo-Téguo, Jean Michel Mérillon, Laurie T Butler, Claire M Williams, Jeremy P E Spence. Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. PloS one. vol 8. issue 5. 2014-01-10. PMID:23723987. |
however, unlike protein levels of bdnf, the regional enhancement of bdnf mrna expression in the hippocampus appeared to be predominantly enhanced by anthocyanins. |
2014-01-10 |
2023-08-12 |
rat |
| Seung-Hwan Kwon, Shi-Xun Ma, Hyun-Joong Joo, Seok-Yong Lee, Choon-Gon Jan. Inhibitory Effects of Eucommia ulmoides Oliv. Bark on Scopolamine-Induced Learning and Memory Deficits in Mice. Biomolecules & therapeutics. vol 21. issue 6. 2014-01-09. PMID:24404337. |
eue also markedly increased brain-derived neurotrophic factor (bdnf) and phosphorylation of camp element binding protein (creb) in the hippocampus of scopolamine-induced mice. |
2014-01-09 |
2023-08-12 |
mouse |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
brain-derived neurotrophic factor (bdnf) val(66)met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. |
2014-01-03 |
2023-08-12 |
human |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
a val(66)met single-nucleotide polymorphism (snp) in the brain-derived neurotrophic factor (bdnf) gene impairs activity-dependent bdnf release in cultured hippocampal neurons and predicts impaired memory and exaggerated basal hippocampal activity in healthy humans. |
2014-01-03 |
2023-08-12 |
human |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
several clinical genetic association studies along with multi-modal evidence for hippocampal dysfunction in schizophrenia indirectly suggest a relationship between schizophrenia and genetically determined bdnf function in the hippocampus. |
2014-01-03 |
2023-08-12 |
human |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
potentially consistent with the hypothesis that cellular sequelae of the bdnf val(66)met snp interface with aspects of schizophrenic hippocampal and frontotemporal dysfunction, these results warrant future investigation to understand the contributions of unique patient trait or state variables to these robust interactions. |
2014-01-03 |
2023-08-12 |
human |
| Karlie A Intlekofer, Carl W Cotma. Exercise counteracts declining hippocampal function in aging and Alzheimer's disease. Neurobiology of disease. vol 57. 2013-12-31. PMID:22750524. |
accumulating research shows that physical activity reinstates hippocampal function by enhancing the expression of brain-derived neurotrophic factor (bdnf) and other growth factors that promote neurogenesis, angiogenesis, and synaptic plasticity. |
2013-12-31 |
2023-08-12 |
human |
| Fuencisla Pilar-Cuéllar, Rebeca Vidal, Alvaro Díaz, Elena Castro, Severiano dos Anjos, Jesús Pascual-Brazo, Raquel Linge, Veronica Vargas, Helena Blanco, Beatriz Martínez-Villayandre, Ángel Pazos, Elsa M Valdizá. Neural plasticity and proliferation in the generation of antidepressant effects: hippocampal implication. Neural plasticity. vol 2013. 2013-12-30. PMID:23862076. |
we will especially focus on the hippocampal cellularity and plasticity modulation by serotonin, trophic factors as brain-derived neurotrophic factor (bdnf), and vascular endothelial growth factor (vegf) through intracellular signalling pathways-camp, wnt/ β -catenin, and mtor. |
2013-12-30 |
2023-08-12 |
Not clear |
| William C Wetsel, Ramona M Rodriguiz, Johann Guillemot, Estelle Rousselet, Rachid Essalmani, Il Hwan Kim, Jesse C Bryant, Jadwiga Marcinkiewicz, Roxane Desjardins, Robert Day, Daniel B Constam, Annik Prat, Nabil G Seida. Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 43. 2013-12-30. PMID:24101515. |
in vivo we observe that bdnf and pc7 mrnas are colocalized in mouse hippocampus and amygdala and that mature bdnf protein levels are reduced in these brain areas in pc7 ko mice but not in the hippocampus of pc1/3 ko mice. |
2013-12-30 |
2023-08-12 |
mouse |
| Fabiana K Ludka, Andréa D E Zomkowski, Mauricio P Cunha, Tharine Dal-Cim, Ana Lúcia B Zeni, Ana Lúcia S Rodrigues, Carla I Tasc. Acute atorvastatin treatment exerts antidepressant-like effect in mice via the L-arginine-nitric oxide-cyclic guanosine monophosphate pathway and increases BDNF levels. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 5. 2013-12-27. PMID:22682406. |
increased the hippocampal bdnf levels, which is an effect that has not been observed in imipramine-treated mice. |
2013-12-27 |
2023-08-12 |
mouse |
| Fabiana K Ludka, Andréa D E Zomkowski, Mauricio P Cunha, Tharine Dal-Cim, Ana Lúcia B Zeni, Ana Lúcia S Rodrigues, Carla I Tasc. Acute atorvastatin treatment exerts antidepressant-like effect in mice via the L-arginine-nitric oxide-cyclic guanosine monophosphate pathway and increases BDNF levels. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 5. 2013-12-27. PMID:22682406. |
these results demonstrate that atorvastatin exerts an antidepressant-like effect and point to dependence on the inhibition of nmda receptors and no-cgmp synthesis, and on the increase of hippocampal bdnf levels. |
2013-12-27 |
2023-08-12 |
mouse |
| Alessandra Tamburella, Gian Marco Leggio, Vincenzo Micale, Andrea Navarria, Claudio Bucolo, Valentina Cicirata, Filippo Drago, Salvatore Salomon. Behavioural and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:22695046. |
these experiments were undertaken to assess the mechanisms underlying the antidepressant-like effects of the neurokinin-2 (nk(2)) receptor antagonist saredutant (sr48968) in rats tested in the forced swim test (fst), by analysing hippocampal brain-derived neurotrophic factor (bdnf) and plasma corticosterone [as index of hypothalamic-pituitary-adrenal (hpa) axis activity]. |
2013-12-27 |
2023-08-12 |
rat |
| Alessandra Tamburella, Gian Marco Leggio, Vincenzo Micale, Andrea Navarria, Claudio Bucolo, Valentina Cicirata, Filippo Drago, Salvatore Salomon. Behavioural and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:22695046. |
this stress procedure increased immobility and decreased swimming behaviour in the fst; furthermore, it lowered hippocampal bdnf protein expression and increased plasma corticosterone levels. |
2013-12-27 |
2023-08-12 |
rat |
| Alessandra Tamburella, Gian Marco Leggio, Vincenzo Micale, Andrea Navarria, Claudio Bucolo, Valentina Cicirata, Filippo Drago, Salvatore Salomon. Behavioural and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:22695046. |
moreover, saredutant increases bdnf expression in the hippocampus, confirming the role of nk(2) receptor blockade in bdnf activation following stressor application. |
2013-12-27 |
2023-08-12 |
rat |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
xiangshao granule exerts antidepressive effects in a depression mouse model by ameliorating deficits in hippocampal bdnf and trkb. |
2013-12-24 |
2023-08-12 |
mouse |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
serum crh, cort, and acth levels were significantly increased in depression mice compared with control (p < 0.05) and the expression levels of hippocampal bdnf and trkb were reduced in the model group (p < 0.05). |
2013-12-24 |
2023-08-12 |
mouse |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
however, xiangshao granule treatment remarkably rescued the decrease in the body weight (p < 0.05), increased crossings in the open field test (p < 0.05), upregulated the expression of hippocampal bdnf and trkb expression, and reduced the serum crh, cort, and acth concentrations compared with the depression group (p < 0.05). |
2013-12-24 |
2023-08-12 |
mouse |