| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saisai Ji, Yingli Qu, Qi Sun, Feng Zhao, Yidan Qiu, Zheng Li, Yawei Li, Haocan Song, Miao Zhang, Wenli Zhang, Hui Fu, Jiayi Cai, Zhuona Zhang, Ying Zhu, Zhaojin Cao, Yuebin Lv, Xiaoming Sh. Mediating Role of Liver Dysfunction in the Association between Arsenic Exposure and Diabetes in Chinese Adults: A Nationwide Cross-Sectional Study of China National Human Biomonitoring (CNHBM) 2017-2018. Environmental science & technology. 2024-01-29. PMID:38285630. |
generalized linear mixed models and restricted cubic splines models were used to examine the relationships among tas levels, serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) concentrations, and diabetes prevalence. |
2024-01-29 |
2024-02-01 |
human |
| Suli He, Chao Yan, Min Wu, Haiyan Peng, Ren Li, Jian Wan, Xin Ye, Hongmao Zhang, Shumao Din. Dibutyl phthalate adsorbed on multi-walled carbon nanotubes can aggravate liver injury in mice via the Jak2/STAT3 pathway. Toxicology and industrial health. 2024-01-29. PMID:38285958. |
additionally, alanine aminotransferase (alt) and aspartate aminotransferase (ast) were elevated in the liver, and glucose, pyruvate, triglyceride (tg), and total cholesterol (t-cho) were significantly reduced, suggesting compromised liver function. |
2024-01-29 |
2024-02-01 |
mouse |
| Shurong Li, Xiang Li, Fang Xie, Yang Bai, Jun M. Melatonin reduces myocardial cell damage in myocardial ischemia/reperfusion rats by inhibiting NLRP3 activation. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 15. 2024-01-27. PMID:38279429. |
the experimental results showed that mel reduced the myocardial infarction area, decreased aspartate aminotransferase (ast), creatine kinase myocardial band (ck-mb), lactate dehydrogenase (ldh) and malondialdehyde (mda), and significantly inhibited the expression of reactive oxygen species (ros), nlrp3, caspase-1 and apoptosis-associated speck-like protein containing a card (asc), but its effect on superoxide dismutase (sod) was opposite. |
2024-01-27 |
2024-01-29 |
rat |
| Reda S Mohamed, Mahmoud Alagawany, Adel I Attia, Fawzy S A Ismail, Ayman S Salah, Alessandro Di Cerbo, Mahmoud M Azzam, Mahmoud M Arafa, Mohamed M El-Mekkaw. The role of chamomile oil against ochratoxin A in quail breeders: productive and reproductive performances, egg quality, and blood metabolites. Poultry science. vol 103. issue 3. 2024-01-25. PMID:38271757. |
a significant decline (p < 0.05) in the levels of serum protein (total protein and globulin) was also recorded in ota-contaminated groups, along with elevated serum levels of liver enzymes such as alanine transaminase (alt) and aspartate transaminase (ast) and kidney function test as urea and creatinine levels (p < 0.05). |
2024-01-25 |
2024-01-28 |
Not clear |
| Fatma Farrag Ali, Mostafa Mourad Mohammed, Youssef Hussein, Manar Fouli Gaber Ibrahi. Targeting PI3K/p-Akt/eNOS, Nrf2/HO-1, and NF-κB/p53 signaling pathways by angiotensin 1-7 protects against liver injury induced by ischemia-reperfusion in rats. Cell biochemistry and function. vol 42. issue 1. 2024-01-25. PMID:38269514. |
the levels of reduced glutathione (gsh), aspartate aminotransferase (ast), alanine aminotransferase (alt), tumor necrosis factor-α (tnf-α), and interleukin-6 (il-6) in serum were estimated. |
2024-01-25 |
2024-01-27 |
rat |
| Hamid Reza Niazkar, Jalil Moshari, Abdoljavad Khajavi, Mohammad Ghorbani, Majid Niazkar, Aida Negar. Application of multi-gene genetic programming to the prognosis prediction of COVID-19 using routine hematological variables. Scientific reports. vol 14. issue 1. 2024-01-24. PMID:38263446. |
also, sensitivity analysis indicated that blood urea nitrogen (bun) and aspartate aminotransferase (ast) play key roles in the prognosis of covid-19 patients. |
2024-01-24 |
2024-01-26 |
Not clear |
| M U Ijaz, N Nadeem, A Hamza, M H Almutairi, U Atiqu. Didymin protects against polystyrene nanoplastic-induced hepatic damage in male albino rats by modulation of Nrf-2/Keap-1 pathway. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 57. 2024-01-24. PMID:38265346. |
the levels of alanine transaminase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) were increased in ps-nps-exposed rats. |
2024-01-24 |
2024-01-26 |
rat |
| Curtis Marcoux, Rima M Saliba, Whitney Wallis, Sajad J Khazal, Dristhi Ragoonanan, Gabriela Rondon, Priti Tewari, Uday R Popat, Betul Oran, Amanda L Olson, Qaiser Bashir, Muzaffar H Qazilbash, Amin Alousi, Chitra Hosing, Yago Nieto, Gheath Alatrash, David C Marin, Katayoun Rezvani, Issa F Khouri, Samer A Srour, Richard E Champlin, Elizabeth J Shpall, Partow Kebriae. Incidence and Risk Factors of Early Onset VOD/SOS Differ in Younger vs Older Adults After Stem Cell Transplantation. Blood advances. 2024-01-24. PMID:38266155. |
incidence of vod in patients > 25 years of age consistently ranged between 3-5% across most risk factors evaluated, with only hepatic factors (baseline elevation of bilirubin, aspartate transferase (ast), alanine aminotransferase (alt)) or gemtuzumab exposure associated with increased rates of vod. |
2024-01-24 |
2024-01-27 |
Not clear |
| Chenglong Fei, Lei Liu, Hedong Qi, Yuyang Peng, Jingfen Han, Chunru Wang, Xue L. Curdlan-Decorated Fullerenes Mitigate Immune-Mediated Hepatic Injury for Autoimmune Hepatitis Therapeutics via Reducing Macrophage Infiltration. ACS applied materials & interfaces. 2024-01-24. PMID:38267397. |
the regulation of hepatic inflammation contributes to inhibiting inflammatory cytokines-induced hepatocyte apoptosis, decreasing the serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) contents and thus ameliorating immune-mediated hepatic injury. |
2024-01-24 |
2024-01-27 |
mouse |
| Jiehao Liu, Fahim UllahKhan, Shen Jin, Yueping Zheng, Jianan Xu, Houyong Fan, Youji Wang, Menghong H. Indexing serum and mucous biochemical parameters of endangered Chinese sturgeon Acipenser sinensis with implications for health assessment. Journal of fish biology. 2024-01-23. PMID:38254334. |
serum and mucous samples were obtained from chinese sturgeon, and the levels of total protein (tp), alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), lactate dehydrogenase (ldh), creatine kinase (ck), lactic acid (ld), acid phosphatase (acp), lysozyme (lyz), glucose (glu), and cortisol were determined. |
2024-01-23 |
2024-01-25 |
Not clear |
| Juan Li, Yanbo Liu, Yijing Li, Tianning Sun, Hongbing Xiang, Zhigang H. The Role of Gut Microbiota and Circadian Rhythm Oscillation of Hepatic Ischemia-Reperfusion Injury in Diabetic Mice. Biomedicines. vol 12. issue 1. 2024-01-23. PMID:38255161. |
the liver pathological score and the serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) were analyzed to evaluate liver injury. |
2024-01-23 |
2024-01-25 |
mouse |
| Yongyan Ren, Zhenxia Xu, Zhixian Qiao, Xu Wang, Chen Yan. Flaxseed Lignan Alleviates the Paracetamol-Induced Hepatotoxicity Associated with Regulation of Gut Microbiota and Serum Metabolome. Nutrients. vol 16. issue 2. 2024-01-23. PMID:38257189. |
the findings demonstrated that administering 800 mg/kg/d flaxseed lignan prior to pam significantly decreased the serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and total bilirubin (tbi) levels, while it increased liver superoxide dismutase (sod) and glutathione (gsh) levels in mice. |
2024-01-23 |
2024-01-25 |
mouse |
| Cong Meng, Yu Liu, Yuping Ming, Cao Lu, Yanggege Li, Yulu Zhang, Dongdong Su, Xueyun Gao, Qing Yua. Enhancing Liver Delivery of Gold Nanoclusters via Human Serum Albumin Encapsulation for Autoimmune Hepatitis Alleviation. Pharmaceutics. vol 16. issue 1. 2024-01-23. PMID:38258120. |
therefore, human serum albumin (hsa)-encapsulated auncs were constructed to achieve enhanced liver targeting and more potent mitigation of con a-induced elevations in plasma aspartate transaminase (ast), alanine transaminase (alt), and liver injury in mice. |
2024-01-23 |
2024-01-25 |
mouse |
| Bradford S Martins, Nia Fogelman, Marshall Tate, Gretchen H Hermes, Rajita Sinh. Effects of prazosin treatment on liver enzymes are moderated by alcohol withdrawal symptoms in individuals with alcohol use disorder. Alcohol, clinical & experimental research. 2024-01-23. PMID:38258493. |
we assessed the effects of prazosin treatment on the liver enzymes alanine transaminase (alt), aspartate transaminase (ast), and gamma-glutamyltransferase (ggt) in individuals with aud. |
2024-01-23 |
2024-01-25 |
Not clear |
| Natalie Zahr, Adolf Pfefferbau. Serum albumin and white matter hyperintensities. Research square. 2024-01-23. PMID:38260299. |
relations between albumin and markers of liver integrity [e.g., aspartate transaminase (ast)] and blood status (e.g., hemoglobin, red blood cell count, red cell distribution width) suggest that in this sample, albumin reflects both liver dysfunction and hematological abnormalities. |
2024-01-23 |
2024-01-25 |
Not clear |
| Yihua Zhang, Hui Li, Xueli Liu, Qiang Wang, Dong Zhao, Ming Su, Zhixin Jia, Shigang She. Integrating Metabolomics and Network Pharmacology to Decipher the Hepatoprotective Effect Mechanisms of Magnesium Isoglycyrrhizinate Injection. Current issues in molecular biology. vol 46. issue 1. 2024-01-22. PMID:38248321. |
the protective effect of mii on the mice model was evaluated using pathological tissue sections and biochemical indices such as alanine transaminase (alt), aspartate aminotransferase (ast), and superoxide dismutase (sod). |
2024-01-22 |
2024-01-24 |
mouse |
| Mark Ayoub, Muhammed Ceesay, Carol Faris, Michael Iannett. Acute Gallstone Pancreatitis in Pregnancy: A Multidisciplinary Approach. Cureus. vol 15. issue 12. 2024-01-22. PMID:38249273. |
other significant labs included elevated alkaline phosphatase (alp) of 125 and mild transaminitis, with alanine transaminase (alt) and aspartate aminotransferase (ast) levels of 84 and 57, respectively. |
2024-01-22 |
2024-01-24 |
Not clear |
| Xiaohuan Lai, Haiyan Chen, Xiaofeng Dong, Guanlin Zhou, Dong Liang, Fei Xu, Hongxia Liu, Yingmin Luo, Hui Liu, Shaogui Wa. AST to ALT ratio as a prospective risk predictor for liver cirrhosis in patients with chronic HBV infection. European journal of gastroenterology & hepatology. 2024-01-22. PMID:38251454. |
serum aspartate aminotransferase (ast) to alanine aminotransferase (alt) ratio (aar) is one of the most frequent indicators to discriminate fibrosis and cirrhosis. |
2024-01-22 |
2024-01-24 |
Not clear |
| Oore-Oluwapo Daramola, Wahab Adekunle Oyeyemi Oyeyemi, Adeniran Oluwadamilare Akinola Akinola, Yinusa Raji Raj. Haematoprotective and Hepatoprotective Effects of Methanolic Leaf Extract of Parquetina nigrescens on Arsenic trioxide-induced Toxicity in Male Wistar Rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 37. issue 2. 2024-01-20. PMID:38243559. |
liver concentrations of malondialdehyde (mda), superoxide dismutase (sod), aspartate aminotransferase (ast), alanine amino transferase (alt) and alkaline phosphatase (alp) activities were determined spectrophotometrically. |
2024-01-20 |
2024-01-22 |
rat |
| Oore-Oluwapo Daramola, Wahab Adekunle Oyeyemi Oyeyemi, Adeniran Oluwadamilare Akinola Akinola, Yinusa Raji Raj. Haematological and biochemical changes in arsenic trioxide-induced toxicity in Wistar rats treated with methanol extract of Parquetina nigrescens leaf. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 37. issue 2. 2024-01-20. PMID:38243571. |
liver concentrations of malondialdehyde (mda), superoxide dismutase (sod), aspartate aminotransferase (ast), alanine amino transferase (alt) and alkaline phosphatase (alp) activities were determined spectrophotometrically. |
2024-01-20 |
2024-01-22 |
rat |