| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karen Pedraza-Escudero, Nayely Garibay-Nieto, Eréndira Villanueva-Ortega, Carlos Omar López-López, Rebeca Galindo-Díaz, Adán Germán Gallardo-Rodríguez, Gloria Eugenia Queipo-García, Alejandra Ruíz-Barranco, María José Garcés-Hernández, Mireya León-Hernández, Estibalitz Laresgoiti-Servitj. Metabolic and Anthropometric Effects of a Randomized Freely Chosen Exercise Prescription Program vs a Video-Based Training Program in Patients With Childhood Obesity: A Randomized Clinical Trial. Cureus. vol 17. issue 3. 2025-04-01. PMID:40166798. |
other outcomes observed were: in epv, there was a decrease in low density lipid (ldl) (p=0.04); alanine aminotransferase (alt) (p=0.002), aspartate aminotransferase (ast) (p=0.001) and uric acid (p=0.003) and an increase in high density lipid (hdl) (p=0. |
2025-04-01 |
2025-04-03 |
human |
| Keyue Wu, Qingyue Meng, Xuhua Nong, Xinye Chen, Yonghong Liu, Simon Wing-Fai Mok, Riming Huang, Xiaoyong Zhan. New insights into the cytotoxic mechanism of marine-fungus-derived citrinin in three-dimensional Hepa1-6 cell model. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2025-03-31. PMID:40164369. |
the results revealed that, after treatment of 60-100 μg/ml mfdc, the increases of reactive oxygen species (ros), lactate dehydrogenase (ldh), aspartate aminotransferase (ast) and alanine aminotransferase (alt) in 2d cell model were more significant than those in 3d cell model. |
2025-03-31 |
2025-04-03 |
Not clear |
| Helai Hussaini, Aiman Waheed, Olaniyi Fadeyi, Tony Boostany, Yusuke Hashimoto, Andrew T Flin. Acute Liver Injury Following Herbal Drink Consumption With Steatosis and Immune Activation: A Case Report. Cureus. vol 17. issue 2. 2025-03-31. PMID:40161146. |
laboratory tests revealed significant liver damage, with aspartate aminotransferase (ast) at 1,043 u/l, alanine aminotransferase (alt) at 1,645 u/l, and total bilirubin at 4.8 mg/dl. |
2025-03-31 |
2025-04-03 |
Not clear |
| Limei Chen, Xiaoxia Miao, Manqiao Wang, Fei Gao, Emmanuel Eric Pazo, Liying Hu, Chen Chen, Yu Shi, Xiuqing Zhu, Xiaorong Li, Juping Li. An Exploration of Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) Platelet Ratio Index (APRI) Scores with Dysglycemia and Diabetic Retinopathy: The Beichen Eye Study. Diabetes, metabolic syndrome and obesity : targets and therapy. vol 18. 2025-03-31. PMID:40161286. |
an exploration of alanine aminotransferase (alt) and aspartate aminotransferase (ast) platelet ratio index (apri) scores with dysglycemia and diabetic retinopathy: the beichen eye study. |
2025-03-31 |
2025-04-03 |
Not clear |
| Limei Chen, Xiaoxia Miao, Manqiao Wang, Fei Gao, Emmanuel Eric Pazo, Liying Hu, Chen Chen, Yu Shi, Xiuqing Zhu, Xiaorong Li, Juping Li. An Exploration of Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) Platelet Ratio Index (APRI) Scores with Dysglycemia and Diabetic Retinopathy: The Beichen Eye Study. Diabetes, metabolic syndrome and obesity : targets and therapy. vol 18. 2025-03-31. PMID:40161286. |
this study aimed to investigate the association of alanine aminotransferase (alt) and aspartate aminotransferase (ast) to platelet ratio index (apri) scores with dysglycemia and dr. |
2025-03-31 |
2025-04-03 |
Not clear |
| Oore-Oluwapo Daramola, Wahab Adekunle Oyeyemi Oyeyemi, Adeniran Oluwadamilare Akinola Akinola, Yinusa Raji Raj. Haematological and biochemical changes in arsenic trioxide-induced toxicity in Wistar rats treated with methanol extract of Parquetina nigrescens leaf. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 39. issue 1. 2025-03-29. PMID:40156818. |
liver concentrations of malondialdehyde (mda), superoxide dismutase (sod), aspartate aminotransferase (ast), alanine amino transferase (alt) and alkaline phosphatase (alp) activities were determined spectrophotometrically. |
2025-03-29 |
2025-04-02 |
rat |
| Michael Gbadegesin, J O Teibo, M Adegoke, G Olajire, Oyeronke A Odunol. D-Ribose-L-Cysteine protects against sodium arsenite-induced hepato-nephrotoxicity in rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 39. issue 1. 2025-03-29. PMID:40156813. |
exposure to sa triggered a significant reduction in the entire weight and relative organ weight, increase in alt (alanine aminotransferase), ast (aspartate aminotransferase), alp (alkaline phosphatase) activities, decrease in liver total protein and increase in serum levels of urea and creatinine. |
2025-03-29 |
2025-04-02 |
rat |
| Xiangqin Lin, Yixiong Cao, Xuehan Wang, Xiaoxue Meng, Junming Deng, Beiping Ta. Optimal dietary phospholipid requirement for juvenile leopard coral grouper (Plectropomus leopardus). Journal of animal science. 2025-03-28. PMID:40153530. |
furthermore, the dietary incorporation of 2% sl led to an upregulation of the relative mrna levels of toll-like receptor 2 (tlr 2), myeloid differentiation factor 88 (myd88), and transforming growth factor β1 (tgfβ1) in the hindgut, but decreased the aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities in serum. |
2025-03-28 |
2025-03-31 |
Not clear |
| Radwa T M Tawfik, Eman M Abd El-Azeem, Sawsan M Elsonbaty, Ehab A Ibrahi. Green-synthesized selenium-hydroxytyrosol nanocomposites attenuate hepatocellular carcinoma in rats by modulating oxidative stress, inflammation, and apoptosis. Naunyn-Schmiedeberg's archives of pharmacology. 2025-03-27. PMID:40146247. |
treatment with se-htnps significantly inhibited serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), and total bilirubin, while increasing serum albumin and total protein levels. |
2025-03-27 |
2025-03-30 |
rat |
| Yujie Pan, Xiankang Xu, Weixue Zhao, Fang Tian, Yanrong Zhao, Tingting Zhang, Hui Yang, Jianzhong Han, Weilin Li. Chitosan-polygalacturonic acid-double-layered liposomes for oleanolic acid delivery: In vitro semi-dynamic digestion, improved cell uptake and liver protection. International journal of biological macromolecules. 2025-03-27. PMID:40147669. |
in the mouse liver injury model, pga-chi-oa-lip effectively reduced the activities of ast (aspartate aminotransferase) and alt (alanine aminotransferase), decreased inflammatory factors, and thus effectively alleviated the infiltration and necrosis of liver cells. |
2025-03-27 |
2025-03-30 |
mouse |
| K Jaszcza, A K Grzegorzewska, A Sachman, A Kalafova, P Massanyi, A Kovacik, R Dupak, M Capcarov. The effect of metformin and sea buckthorn (Hippophae rhamnoides L.) in alleviating the symptoms of type 2 diabetes mellitus in the liver of zucker diabetic fatty rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 76. issue 1. 2025-03-26. PMID:40137850. |
moreover, following biochemical parameters in the blood serum were determined: alanine transaminase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), bilirubin, cholesterol and triglycerides. |
2025-03-26 |
2025-03-30 |
rat |
| b' Marek Lep\\xc3\\xa1\\xc4\\x8dek, Pavol Bo\\xc4\\x8fo, Marta \\xc5\\xa0olt\\xc3\\xa9sov\\xc3\\xa1 Prnov\\xc3\\xa1, M\\xc3\\xa1ria Bu\\xc4\\x8dkov\\xc3\\xa1, Domenico Pangallo, Jelena Pavlovi\\xc4\\x8. Impact of novel Aldose Reductase Inhibitor drug on Gut Microbiota Composition and Metabolic Health in ZDF \\\'Lean\\\' Rats. Chemico-biological interactions. 2025-03-26. PMID:40139546.' |
although there was a slight increase in alanine aminotransferase (alt), our study found that levels of other liver enzymes such as aspartate aminotransferase (ast), alkaline phosphatase (alp) and total bilirubin remained within normal limits, suggesting the observed increase in alt was not indicative of drug-induced liver injury. |
2025-03-26 |
2025-03-30 |
rat |
| Hayley A Ron, Owen Kane, Rose Guo, Caitlin Menello, Nicole Engelhardt, Shaney Pressley, Brenda DiBoscio, Madeline Steffensen, Sanmati Cuddapah, Kim Ng, Can Ficicioglu, Rebecca C Ahrens-Nickla. Five-Year Outcomes of Patients with Pompe Disease Identified by the Pennsylvania Newborn Screen. International journal of neonatal screening. vol 11. issue 1. 2025-03-26. PMID:40136631. |
these patients were evaluated at regular intervals through our multi-disciplinary clinic at the children's hospital of philadelphia (chop) with physical examinations, physical therapy evaluations, muscle biomarkers including creatine kinase (ck), aspartate aminotransferase (ast), alanine aminotransferase (alt), and hexosaminidase 4 levels (hex4), as well as cardiac evaluation at certain points in time. |
2025-03-26 |
2025-03-28 |
Not clear |
| Satoshi Kimura, Hiroaki Sato, Shohei Shimajiri, Toshiyuki Nakayam. An acute aortic dissection prognostic score for predicting early in-hospital mortality in acute thoracic aortic dissection. American heart journal plus : cardiology research and practice. vol 52. 2025-03-25. PMID:40129616. |
this, together with levels of d-dimer, brain natriuretic peptide (bnp), aspartate aminotransferase (ast), and lactate dehydrogenase (ld), may be useful in predicting a prognosis for atad. |
2025-03-25 |
2025-03-27 |
Not clear |
| Jie Gu, Yuehong Shen, Liguo Guo, Zhicheng Chen, Dingyu Zhou, Guixiang Ji, Aihua G. Investigation of the mechanisms of liver injury induced by emamectin benzoate exposure at environmental concentrations in zebrafish: A multi-omics approach to explore the role of the gut-liver axis. Journal of hazardous materials. vol 491. 2025-03-25. PMID:40132265. |
we found that exposure to 1 μg/l emb induced liver damage, manifested as impaired liver function (elevated aspartate aminotransferase (ast) and alanine aminotransferase (alt)), histopathological damage (lipid accumulation), as well as inflammatory and oxidative damage, with a dose - dependent effect. |
2025-03-25 |
2025-03-28 |
zebrafish |
| Min Li, Shuaijun Peng, Jingjing Bu, Siqi Quan, Liming Liu, Zhouli Yue, Linlin Wang, Yucheng L. Glycyrrhizic acid alleviates gefitinib-induced liver injury by regulating the p53/p21 pathway and releasing cell cycle arrest. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2025-03-23. PMID:40122507. |
liver injury was induced in mice through daily oral administration of gefitinib (400 mg/kg) for 16 days, with hepatotoxicity was assessed through serum alanine transaminase (alt) and aspartate transaminase (ast) levels, and hepatic histopathology. |
2025-03-23 |
2025-03-26 |
mouse |
| Minghao Geng, Yi Cheng, Leizhen Duan, Guangshen Dong, Shuo Yang, Xuecheng Jiao, Weihua Jia, Hui Huang, Ming Dou, Xiaoli Fu, Fangfang Yu, Yuhui Du, Guoyu Zhou, Yue B. Inflammation May Mediate the Effects of Fluoride on Liver and Kidney Function of Adults: Cross-Sectional Studies in China. Biological trace element research. 2025-03-21. PMID:40117029. |
urine and blood samples were collected for determinations of urinary fluoride (uf), aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (tbil), blood urea nitrogen (bun), serum creatinine (scr), serum uric acid (sua), and white blood cell (wbc) counts. |
2025-03-21 |
2025-03-24 |
human |
| Zhe Liu, Jing Hou, MeiYuan Tian, YaoGang Zhang, DengLiang Huang, Na Zhao, Yanyan Ma, Sen Cu. Hypoxia ameliorates high-fat-diet-induced hepatic lipid accumulation by modulating the HIF2α/PP4C signaling. Cellular signalling. 2025-03-20. PMID:40112904. |
compared with those in the 2200 m hfd group, body weight, triglyceride (tg), total cholesterol (tc), amino alanine transferase (alt), aspartate transaminase (ast), and lipid accumulation were lower in the 4500 m hfd group (p < 0.05). |
2025-03-20 |
2025-03-23 |
Not clear |
| Zhongfeng Cheng, Kerun Cheng, Yan Tang, Xueqiong Duan, Yangshan Fu, Hongdan Duan, Yong Y. α-Amanitin aggravates hepatic injury by activating oxidative stress and mitophagy via peroxiredoxin 6 inhibition. Immunologic research. vol 73. issue 1. 2025-03-20. PMID:40108092. |
in addition, the levels of alanine aminotransferase (alt), aspartate transaminase (ast) and mitochondrial reactive oxygen species (mtros) were observed to increase in the α-ama-treated groups, whereas antioxidants superoxide dismutase (sod) levels were reduced. |
2025-03-20 |
2025-03-22 |
mouse |
| Dachuan Jin, Shunqin Jin, Guoping Sheng, Zhongfeng Cui, Peng Gao, Guangming L. Effects of Curcumin on Postmenopausal Women's Health: A Systematic Review and Meta-Analysis. Phytotherapy research : PTR. 2025-03-19. PMID:40105038. |
we found that curcumin reduced systolic (smd -0.51, 95% ci -0.83 to 0.19, p = 0.002) and diastolic blood pressure (smd -0.63, 95% ci -0.96 to -0.30, p = 0.005), increased total antioxidant capacity (smd 0.93, 95% ci 0.15 to 1.72, p = 0.020) and superoxide dismutase levels (smd 0.30, 95% ci 0.04 to 0.56, p = 0.026), decreased aspartate aminotransferase (ast) (smd -0.36, 95% ci -0.66 to -0.06, p = 0.020), and improved vasomotor (smd -0.39, 95% ci -0.65 to -0.13, p = 0.003) symptoms. |
2025-03-19 |
2025-03-21 |
human |