| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiangshu Wang, Haozhe Tian, Jie Chen, Di Huang, Feng Ding, Tao Ma, Jin Xi, Chengzhu Wu, Yuxin Zhan. Isobavachalcone attenuates liver fibrosis via activation of the Nrf2/HO-1 pathway in rats. International immunopharmacology. vol 128. 2024-01-03. PMID:38171054. |
the results showed that ibc significantly ameliorated the pathological damage and collagen deposition in liver tissues; it also reduced the levels of hydroxyproline (hyp), alanine aminotransferase (alt), and aspartate aminotransferase (ast). |
2024-01-03 |
2024-01-06 |
rat |
| Mahdi Al Dhafiri, Feroze Kaliyadan, Sara Almukhaimar, Fatemah Alsultan, Elham Al Hayim, Roaa Alnaim, Alaa Aldossar. Isotretinoin Use and Liver Enzymes Changes: A Single-Center Study in Saudi Arabia. Cureus. vol 15. issue 12. 2024-01-01. PMID:38161524. |
it determined the baseline, second, and last readings of aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2024-01-01 |
2024-01-05 |
Not clear |
| Justin M Conley, Christy S Lambright, Nicola Evans, Jacqueline Bangma, Jermaine Ford, Donna Hill, Elizabeth Medlock-Kakaley, L Earl Gra. Maternal and Neonatal Effects of Maternal Oral Exposure to Perfluoro-2-methoxyacetic Acid (PFMOAA) during Pregnancy and Early Lactation in the Sprague-Dawley Rat. Environmental science & technology. 2024-01-01. PMID:38163761. |
pup survival was significantly reduced at ≥125 mg/kg, and at necropsy on pnd2 both maternal and neonatal animals displayed increased liver weights, increased serum aspartate aminotransferase (ast), and reduced serum thyroid hormones at all doses (≥10 mg/kg). |
2024-01-01 |
2024-01-05 |
human |
| Miao Yang, Yuxuan Lu, Weifeng Mao, Liping Ha. New insight into PAH4 induced hepatotoxicity and the dose-response assessment in rats model. Chemosphere. 2023-12-28. PMID:38154670. |
our results showed pah4 exposure increased relative liver weight and serum aspartate aminotransferase (ast) activity and caused hepatocyte swelling and degeneration, implying hepatotoxicity induced by pah4. |
2023-12-28 |
2023-12-31 |
rat |
| Mayra Denise Herrera, Iza Fernanda Pérez-Ramírez, Rosalía Reynoso-Camacho, Luis Roberto Reveles-Torres, Miguel Servín-Palestina, Angelica Judith Granados-López, Claudia Araceli Reyes-Estrada, Jesús Adrián Lópe. Chemometric Evaluation of RI-Induced Phytochemicals in Molecules (Basel, Switzerland). vol 28. issue 24. 2023-12-23. PMID:38138473. |
the intake of healthy foods can improve the activity of enzymes like aspartate and alanine aminotransferases (ast, alt), γ-glutaminyl transferase (ggt), and alkaline phosphatase (alp). |
2023-12-23 |
2023-12-25 |
rat |
| Hao Li, Haibo Yu, Xiaotian Zhang, Wenhao Huang, Cheng Zhang, Chi Wang, Qinfeng Gao, Shuanglin Don. Temperature acclimation improves high temperature tolerance of rainbow trout (Oncorhynchus mykiss) by improving mitochondrial quality and inhibiting apoptosis in liver. The Science of the total environment. 2023-12-22. PMID:38135090. |
secondly, the levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in serum and malondialdehyde (mda) in liver of ca + hs group significantly decreased compared to those in hs group without ta, indicating the reduction of liver injury by ca. |
2023-12-22 |
2023-12-25 |
Not clear |
| Muhammad Haroon Aslam, Noor Khan, Mahroze Fatima, Muhammad Afzal Rashid, Simon J Davie. Strategic replacement of soybean meal with local cotton seed meal on growth performance, body composition, and metabolic health status indicators in the major South Asian carp Catla catla for aquaculture. PloS one. vol 18. issue 12. 2023-12-22. PMID:38134190. |
alanine transaminase (alt) and aspartate transaminase (ast) levels increased significantly (p<0.05) with increasing dietary csm levels, while alkaline phosphatase (alp) levels remained the same. |
2023-12-22 |
2023-12-25 |
cat |
| Jiajun Qiu, Maobin Kuang, Shiming He, Changhui Yu, Chao Wang, Xin Huang, Guotai Sheng, Yang Zo. Gender perspective on the association between liver enzyme markers and non-alcoholic fatty liver disease: insights from the general population. Frontiers in endocrinology. vol 14. 2023-12-21. PMID:38125795. |
this study aims to comprehensively analyze and compare the associations of alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transferase (ggt) with nafld from a gender perspective. |
2023-12-21 |
2023-12-23 |
Not clear |
| Marcus Maximilian Mücke, Sylvia Fong, Graham R Foster, David Lillicrap, Wolfgang Miesbach, Stefan Zeuze. Adeno-associated viruses for gene therapy - clinical implications and liver-related complications, a guide for hepatologists. Journal of hepatology. 2023-12-19. PMID:37890721. |
however, the introduction of foreign dna into hepatocytes is associated with a risk of hepatic reactions, with raised alt (alanine aminotransferase) and ast (aspartate aminotransferase) being - so far - the most commonly reported side effects. |
2023-12-19 |
2023-12-23 |
Not clear |
| Su-Wen Chen, Guo-Liang Yin, Chao-Yuan Song, De-Cheng Meng, Wen-Fei Yu, Xin Zhang, Ya-Nan Feng, Peng-Peng Liang, Feng-Xia Zhan. [Diosgenin alleviates NAFLD induced by a high-fat diet in rats via mTOR/SREBP-1c/HSP60/MCAD/SCAD signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 19. 2023-12-19. PMID:38114120. |
the levels of triglyceride(tg), total cholesterol(tc), alanine transaminase(alt), and aspartate transaminase(ast) in the serum were determined by the biochemical method. |
2023-12-19 |
2023-12-23 |
rat |
| Cao Dai, Lin Peng, Yanjie Li, Zhendong Li, Da Chen, Fei Wang, Nan Li. Distribution of per- and polyfluoroalkyl substances in blood, serum, and urine of patients with liver cancer and associations with liver function biomarkers. Journal of environmental sciences (China). vol 139. 2023-12-19. PMID:38105065. |
in addition, multiple regression models adjusted for age, gender and bmi found that increased serum perfluorobutane sulfonic acid (pfbs), perfluoroheptane sulfonic acid (pfhps) and perfluorohexylphosphonic acid (pfhxpa) conentrations are correlated with elevated alkaline phosphatase (alp), aspartate aminotransferase (ast), and alpha-fetoprotein (afp) (p < 0.05). |
2023-12-19 |
2023-12-21 |
Not clear |
| Ningning Yao, Qing Hou, Yu Liang, Xin Cao, Bochen Sun, Lijuan Wei, Ruifang Sun, Jianzhong Ca. Serum aspartate aminotransferase, a novel potential biomarker of prognosis in extranodal natural killer/T cell lymphoma, nasal type. Cancer biomarkers : section A of Disease markers. 2023-12-18. PMID:38108343. |
aspartate aminotransferase (ast), an indicator of liver cell damage, was related to the prognosis of certain malignant tumors. |
2023-12-18 |
2023-12-21 |
Not clear |
| Deng-Lai Li, Si-Ying Liu, Rui Zhu, Si-Tong Meng, Yin-Tao Wang, Zhi-Yong Yang, Liang Li, Xiao-Fang Wei, Guo-Jun Shang, Hao-Tong Wang, Zi-Hui Qu, Ya-Nan Quan, Li-Fang W. Potential protective effects of sodium butyrate on glycinin-induced oxidative stress, inflammatory response, and growth inhibition in Cyprinus carpio. Fish physiology and biochemistry. 2023-12-15. PMID:38099983. |
sb (1.50-2.25 g/kg) increased the activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in the hepatopancreas and reduced the activities of ast and alt in the serum. |
2023-12-15 |
2023-12-17 |
cat |
| Fahimeh Chekneh, Hamideh Ghodrati Azadi, Hasan Baghshani, Zahra Moosav. The Hepatorenal Protective Potential of Caffeic Acid Consumption on the Arsenic-Exposed Syrian Mice. Biological trace element research. 2023-12-15. PMID:38102533. |
arsenic administration significantly increased aspartate aminotransferase (ast), alanine aminotransferase (alt), ldh, urea, and creatinine concentrations (p < 0.05). |
2023-12-15 |
2023-12-18 |
mouse |
| Hao Niu, Pablo Solis-Muñoz, Miren García-Cortés, Judith Sanabria-Cabrera, Mercedes Robles-Diaz, Rocío Romero-Flores, Elvira Bonilla-Toyos, Aida Ortega-Alonso, José M Pinazo-Bandera, María R Cabello, Fernando Bessone, Nelia Hernandez, M Isabel Lucena, Raúl J Andrade, Inmaculada Medina-Caliz, Ismael Alvarez-Alvare. Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification. Pharmacological research. vol 199. 2023-12-14. PMID:38072217. |
patients with pda were older (p = 0.009), had higher aspartate aminotransferase (ast) levels (p = 0.047), lower platelet count (p = 0.011) and higher liver-related mortality than those without a history of drug allergies (11% vs. 1.6%, p < 0.001). |
2023-12-14 |
2023-12-17 |
Not clear |
| Mohamed E Abd El-Hack, Mohamed F AboElMaati, Wafaa F Abusudah, Ohaad F Awlya, Najlaa H Almohmadi, Walid Fouad, Hanan S Mohamed, Islam M Youssef, Naif A Al-Gabri, Sarah I Othman, Ahmed A Allam, Ayman E Taha, Guillermo Tellez-Isaias, Amira M Mansou. Consequences of dietary cinnamon and ginger oils supplementation on blood biochemical parameters, oxidative status, and tissue histomorphology of growing Japanese quails. Poultry science. vol 103. issue 2. 2023-12-14. PMID:38096669. |
results showed that adding herbal oils significantly (p < 0.05) decreased the aspartate aminotransferase (ast) and urea levels compared to control and colistin groups. |
2023-12-14 |
2023-12-17 |
Not clear |
| Long Liu, Na Yang, Yueji Chen, Zhihao Xu, Qingwei Zhang, Xiuxiu Miao, Yanan Zhao, Geng Hu, Liying Liu, Zhi Song, Xianyao L. Effects of fulvic acid on broiler performance, blood biochemistry, and intestinal microflora. Poultry science. vol 103. issue 2. 2023-12-14. PMID:38096671. |
fua supplement significantly improved aspartate aminotransferase (ast) activity in the group iii on d 35 (p < 0.05) and the serum levels of iga and igg on d 21 and d 35 (p < 0.05), but reduced glutathione peroxidase (gsh-px) level on d 21 (p < 0.05) and malondialdehyde (mda) level in serum on d 35 (p < 0.05). |
2023-12-14 |
2023-12-17 |
Not clear |
| Yuansong Zhuang, Quanxu An, Fuhang Wang, Dongjian Han, Zhentao Qiao, Qingjiao Jiang, Miaomiao Liu, Yuhang Li, Jiahong Shangguan, Xuanye Bi, Deliang She. The role of circulating biomarkers in predicting the 30-day mortality of immune checkpoint inhibitors-related myocarditis: a retrospective cohort study. Internal and emergency medicine. 2023-12-12. PMID:38085435. |
after adjusting for potential confounding factors using multivariate analysis tools, we demonstrated the excellent performance of biomarkers in predicting 30-day mortality in patients with icis-m, including plt (hazard ratio (hr), 1.07; 95% confidence interval (95%ci), 1.01-1.14; p = 0.028), alt (hr, 1.23; 95%ci, 1.06-1.41; p = 0.005), ast(hr, 1.06; 95%ci, 1.01-1.10; p = 0.015), ldh (hr, 1.15; 95%ci, 1.04-1.26; p = 0.004), troponin i(hr, 1.44; 95%ci, 1.09-1.89; p = 0.009), plr (blood plate/lymphocyte) (hr, 1.04; 95% ci, 1.01-1.07; p = 0.024), lar (lactate dehydrogenase/albumin) (hr, 1.05; 95%ci, 1.01-1.09; p = 0.012), and aar (aspartate transaminase/albumin) (hr, 1.18; 95%ci, 1.00-1.39; p = 0.048). |
2023-12-12 |
2023-12-17 |
Not clear |
| Alaa Elmetwalli, Neamat H Kamosh, Rania El Safty, Amany I Youssef, Mohammed M Salama, Khaled M Abd El-Razek, Tarek El-Sewed. Novel phloretin-based combinations targeting glucose metabolism in hepatocellular carcinoma through GLUT2/PEPCK axis of action: in silico molecular modelling and in vivo studies. Medical oncology (Northwood, London, England). vol 41. issue 1. 2023-12-11. PMID:38078989. |
we have measured the expression of the glucose transporter 2 (glut2), phosphoenolpyruvate carboxykinases (pepck), caspase-3, beclin 1, cyclin d1, and cytokeratin 18 genes; blood glucose and atp levels; alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities. |
2023-12-11 |
2023-12-17 |
mouse |
| Ebrahim Salimi-Sabour, Ramazan-Ali Tahri, Amirhossein Asgari, Maryam Ghorban. The novel hepatoprotective effects of silibinin-loaded nanostructured lipid carriers against diazinon-induced liver injuries in male mice. Pesticide biochemistry and physiology. vol 197. 2023-12-10. PMID:38072518. |
alanine (alt) and aspartate (ast) aminotransferase levels, oxidative stress biomarkers, inflammatory cytokines, and histopathological alterations were assessed. |
2023-12-10 |
2023-12-17 |
mouse |