Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ryuichi Kawamoto, Asuka Kikuchi, Daisuke Ninomiya, Teru Kumag. Aspartate Aminotransferase/Alanine Aminotransferase Ratio: A Predictor of All-Cause Mortality Rate Among Japanese Community-Dwelling Individuals. Cureus. vol 16. issue 1. 2024-02-13. PMID:38347978. |
introduction an elevated ratio of aspartate aminotransferase (ast) to alanine aminotransferase (alt) not only independently affects aging-related health but also plays a critical role in mortality. |
2024-02-13 |
2024-02-15 |
human |
Fumin Wang, Jingming Lu, Tian Yang, Yaoxing Ren, Francesca Ratti, Hugo P Marques, Silvia Silva, Olivier Soubrane, Vincent Lam, George A Poultsides, Irinel Popescu, Razvan Grigorie, Sorin Alexandrescu, Guillaume Martel, Aklile Workneh, Alfredo Guglielmi, Tom Hugh, Luca Aldrighetti, Itaru Endo, Yi Lv, Xu-Feng Zhang, Timothy M Pawli. Perioperative Changes in Serum Transaminase Levels: Impact on Postoperative Morbidity Following Liver Resection of Hepatocellular Carcinoma. Annals of surgery. 2024-02-13. PMID:38348655. |
to define how dynamic changes in pre- versus post-operative serum aspartate aminotransferase (ast) and alanine aminotransaminase (alt) levels may impact postoperative morbidity after curative-intent resection of hepatocellular carcinoma (hcc). |
2024-02-13 |
2024-02-15 |
Not clear |
Sepehr Sadafi, Ali Azizi, Shahab Rezaeian, Yahya Pasda. Association between healthy beverage index and nonalcoholic fatty liver disease in the Ravansar noncommunicable disease cohort study. Scientific reports. vol 14. issue 1. 2024-02-13. PMID:38351106. |
there was no correlation between gamma glutamyl transferase (ggt), alanine aminotransferase (alt), alkaline phosphatase (alp) and aspartate transaminase (ast) levels with hbi. |
2024-02-13 |
2024-02-16 |
human |
Siwanon Nawalerspanya, Jarukit Tantipisit, Suraphon Assawasuwannakit, Apichat Kaewdech, Naichaya Chamroonkul, Pimsiri Sripongpu. Non-Invasive Serum Biomarkers for the Diagnosis of Cirrhosis in Patients with Autoimmune Hepatitis (AIH) and AIH-Primary Biliary Cholangitis Overlap Syndrome (AIH-PBC): Red Cell Distribution Width to Platelet Ratio (RPR) Yielded the Most Promising Result. Diagnostics (Basel, Switzerland). vol 14. issue 3. 2024-02-10. PMID:38337781. |
laboratory data were collected to calculate the following scores: red cell distribution width to platelet ratio (rpr), aspartate aminotransferase/platelet ratio index (apri), fibrosis-4 index (fib-4), aspartate aminotransferase (ast) to alanine aminotransferase (alt) ratio (aar), neutrophil-to-lymphocyte ratio (nlr), and lymphocyte-to-platelet ratio (lpr). |
2024-02-10 |
2024-02-12 |
Not clear |
Penghui Zhao, Yinchen Hou, Xinyang Chen, Mingyi Zhang, Zheyuan Hu, Lishui Chen, Jihong Huan. High Fischer Ratio Oligopeptides of Gluten Alleviate Alcohol-Induced Liver Damage by Regulating Lipid Metabolism and Oxidative Stress in Rats. Foods (Basel, Switzerland). vol 13. issue 3. 2024-02-10. PMID:38338571. |
following intervention, the levels of serum total cholesterol (tc), triglyceride (tg), alanine aminotransferase (alt), aspartate aminotransferase (ast), and hepatic malondialdehyde (mda) in the rats significantly decreased ( |
2024-02-10 |
2024-02-12 |
rat |
Ik-Rak Jung, Rexford S Ahima, Sangwon F Ki. Time-Restricted Feeding Ameliorates Methionine-Choline Deficient Diet-Induced Steatohepatitis in Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338668. |
here, we show that trf alleviated markers of nash, i.e., reduced hepatic steatosis, liver triglycerides (tg), serum alanine transaminase (alt) and aspartate aminotransferase (ast), inflammation, and fibrosis in mcdd mice. |
2024-02-10 |
2024-02-12 |
mouse |
Nelson Kei, Kam Kuen Cheung, Ka Lee Ma, Tsz Kwan Yau, Susana Lauw, Vincent Wai Sun Wong, Lijun You, Peter Chi Keung Cheun. Effects of Oat β-Glucan and Inulin on Alleviation of Nonalcoholic Steatohepatitis Aggravated by Circadian Disruption in C57BL/6J Mice. Journal of agricultural and food chemistry. 2024-02-09. PMID:38333950. |
compared to cd nash mice, oat β-glucan significantly decreased the liver index, aspartate aminotransferase (ast), and insulin. |
2024-02-09 |
2024-02-11 |
mouse |
Nouf M Alyami, Hussah Alobadi, Saleh Maodaa, Norah S Alothman, Hanouf Almukhlafi, Khadijah N Yaseen, Zainab A Alnakhli, Noura M Alshiban, Doaa M Elnagar, Ahmed Rady, Wed A Alharthi, Bader Almetari, Rafa Almeer, Saud Alarifi, Daoud Al. Determination of dose- and time-dependent hepatotoxicity and apoptosis of Lanthanum oxide nanoparticles in female Swiss albino mice. Environmental science and pollution research international. 2024-02-09. PMID:38334922. |
blood samples were also analyzed to determine liver enzymatic changes, including alkaline phosphatase (alp), alanine transaminase (alt), aspartate aminotransferase (ast), and lipid profiles. |
2024-02-09 |
2024-02-11 |
mouse |
Shweta Jaiswal, Md Meraj Anjum, Dilip Kumar Arya, Sunita Thakur, Prashant Pandey, Payal Deepak, Shubham Kanaujiya, Sneha Anand, Arjun Singh Kaushik, Vikas Mishra, Paruvathanahalli Siddalingam Rajinikant. Surface entrenched β-sitosterol niosomes for enhanced cardioprotective activity against isoproterenol induced cardiotoxicity in rats. International journal of pharmaceutics. 2024-02-09. PMID:38336178. |
administering bs-ns and bs-ha-ns intravenously at a dose of 10 mg/kg showed the ability to significantly decrease the levels of cardiac troponin-i (ctn-i), creatine kinase-mb (ck-mb), lactate dehydrogenase (ldh), aspartate aminotransferase (ast), and lipid peroxidation (mda). |
2024-02-09 |
2024-02-12 |
rat |
Younan Ren, Ying Chen, Emily H Tang, Yixin Hu, Bo Niu, Huaduan Liang, Chuchu Xi, Fang Zhao, Zhengyu Ca. Arbidol attenuates liver fibrosis and activation of hepatic stellate cells by blocking TGF-β1 signaling. European journal of pharmacology. 2024-02-07. PMID:38325795. |
oral administration of arb significantly ameliorated bdl-induced liver injury/fibrosis as reflected by decreased serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), reduced collagen deposition, and diminished mrna expression of fibrosis markers. |
2024-02-07 |
2024-02-10 |
mouse |
Xiangming Wang, Menghui Zhao, Chengguo Ju, Hui Gao, Wei Wan. Protective mechanisms of Juncus effusus and Carbonized Juncus effusus against d-galactosamine-induced acute liver injury in mice. Chemical & pharmaceutical bulletin. 2024-02-07. PMID:38325836. |
the results of the study indicated that j. effusus and carbonized j. effusus suppressed the d-galn-induced generation of serum alanine transaminase (alt), aspartate aminotransferase (ast), hepatic malondialdehyde (mda) and tumor necrosis factor-alpha (tnf-α) was observed. |
2024-02-07 |
2024-02-10 |
mouse |
Randall Argueda. On the significance of aspartate aminotransferase and creatine kinase in wild reptile health studies. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2024-02-06. PMID:38321291. |
in reptile medicine, the enzymes aspartate aminotransferase (ast) and creatine kinase (ck) have been used in clinical diagnostics, where ck is considered an enzyme specific to muscle cell damage, while ast is a nonspecific enzyme that is mainly produced in the liver and muscle. |
2024-02-06 |
2024-02-09 |
Not clear |
Aula Zaini, Hayder Edrees Jawad, Najah Rayish Had. Targeting VEGF using Bevacizumab attenuates sepsis-induced liver injury in a mouse model of cecal ligation and puncture. Journal of medicine and life. vol 16. issue 10. 2024-02-05. PMID:38313162. |
blood samples were collected, and angiopoietin-2 (angpt2), alanine transaminase (alt), and aspartate transaminase (ast) serum levels were measured. |
2024-02-05 |
2024-02-07 |
mouse |
Merve Kahramanoğullari, Mine Erişir, Mine Yaman, Tuba Parlak A. Effects of naringenin on oxidative damage and apoptosis in liver and kidney in rats subjected to chronic mercury chloride. Environmental toxicology. 2024-02-03. PMID:38308452. |
when mercury chloride and treatment groups were compared, the administration of naringenin caused a decrease aspartate transaminase (ast), alanine transaminase (alt), lactate dehydrogenase (ldh) (p < .01), urea, creatinine levels (p < .001) in plasma, mda levels in liver and kidney, sod, gsh-px, gst activities in kidney (p < .001), and increased gsh levels in liver and kidney. |
2024-02-03 |
2024-02-05 |
rat |
Ibrahim T El-Ratel, Mariam M Amara, Malak M Beshara, Mohammed F El Basuini, Sara F Fouda, Khaled H El-Kholy, Tarek A Ebeid, Mahmoud Kamal, Sarah I Othman, Hassan A Rudayni, Ahmed A Allam, Mahmoud Moustafa, Guillermo Tellez-Isaias, Mohamed E Abd El-Hack, Aml Mekaw. Effects of supplemental vitamin A on reproduction and antioxidative status of aged laying hens, and growth, blood indices and immunity of their offspring. Poultry science. vol 103. issue 3. 2024-02-02. PMID:38306808. |
in hatched chicks, all va levels boosted (p < 0.05) hemoglobin, red blood cell count, and serum concentration of total proteins and iga while decreasing eosinophils percentage and aspartate aminotransferase activity (ast) concentration. |
2024-02-02 |
2024-02-05 |
cat |
Hongbo Mi, Ting Zhang, Yue Lu, Jingxin Chen, Xuepeng L. Effect of temperature fluctuation on the physiological stress response of hybrid pearl gentian grouper during waterless keeping alive. Fish physiology and biochemistry. 2024-02-02. PMID:38305929. |
in all treatment groups, the activities of plasma alanine transaminase (alt) and aspartate aminotransferase (ast) and the content of creatinine gradually increased with the prolongation of the survival time. |
2024-02-02 |
2024-02-04 |
cat |
Rawnaq F Al-Shalchi, Fouad K Mohamma. Oxidative Stress-Induced Adverse Effects of Three Statins Following Single or Repetitive Treatments in Mice. Cureus. vol 16. issue 1. 2024-02-01. PMID:38298275. |
brain and plasma glutathione (gsh) and malondialdehyde (mda) levels, as well as liver enzymes activities alanine transaminase (alt) and aspartate transaminase (ast), were determined using commercial kits. |
2024-02-01 |
2024-02-03 |
mouse |
Samia Hussein, Nabil A Soliman, Samih I El Dahmy, Tarek Khamis, Reham Sameh, Fatma M Mostaf. Effectiveness of cannabidiol (CBD) on histopathological changes and gene expression in hepatocellular carcinoma (HCC) model in male rats: the role of Hedgehog (Hh) signaling pathway. Histochemistry and cell biology. 2024-01-31. PMID:38296878. |
measurements were made for alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma glutamyl transferase (ggt), superoxide dismutase (sod), catalase (cat), malondialdehyde (mda), and alpha fetoprotein (afp). |
2024-01-31 |
2024-02-03 |
rat |
Chhabi R Panda, Suchitra Kumari, Manaswini Mangaraj, Saurav Naya. The Evaluation of the Quality Performance of Biochemical Analytes in Clinical Biochemistry Laboratory Using Six Sigma Matrices. Cureus. vol 15. issue 12. 2024-01-31. PMID:38292960. |
results creatinine and high-density lipoprotein (hdl) had sigma metrics of ≤2.0, and chloride, aspartate aminotransferase (ast), and alkaline phosphatase (alp) had sigma values between 2 and 3. |
2024-01-31 |
2024-02-02 |
Not clear |
Guoxiang Xie, Huanming Xiao, Quan Liu, Tianlu Chen, Fengyan Chen, Kejun Zhou, Xiaoning Wang, Ping Liu, Zhifeng Jia, Lei Chen, Xin Deng, Fankun Meng, Zhenhua Zhang, Xiaoling Chi, Wei Ji. LiveBoost: A GB-based prediction system for liver fibrosis in chronic hepatitis B patients in China - A multi-center retrospective study. Heliyon. vol 10. issue 2. 2024-01-31. PMID:38293489. |
the aim of this study was to evaluate the accuracy of liveboost™, a gradient boosting (gb)-based prediction system based on standard biochemical values (ast, alt, platelet count) and age, in chinese patients with chronic hepatitis b (chb) and compare its performance with fib-4 (fibrosis-4 score) and apri (the aspartate transaminase to platelet ratio index). |
2024-01-31 |
2024-02-02 |
Not clear |