All Relations between ache and neurotransmitter

Publication Sentence Publish Date Extraction Date Species
Joana Ribeiro, Henrique Araújo-Silva, Mário Fernandes, Joilna Alves da Silva, Francisco das Chagas L Pinto, Otília Deusdenia L Pessoa, Hélcio Silva Santos, Jane Eire Silva Alencar de Menezes, Andreia C Gome. Petrosamine isolated from marine sponge Petrosia sp. demonstrates protection against neurotoxicity in vitro and in vivo. Natural products and bioprospecting. vol 14. issue 1. 2024-02-22. PMID:38383833. a crucial hallmark associated with this disease is associated with the deficiency of the brain neurotransmitter acetylcholine, due to an affected acetylcholinesterase (ache) activity. 2024-02-22 2024-02-24 zebrafish
Varish Ahmad, Ibrahim Alotibi, Anwar A Alghamdi, Aftab Ahmad, Qazi Mohammad Sajid Jamal, Supriya Srivastav. Computational Approaches to Evaluate the Acetylcholinesterase Binding Interaction with Taxifolin for the Management of Alzheimer's Disease. Molecules (Basel, Switzerland). vol 29. issue 3. 2024-02-10. PMID:38338420. acetylcholinesterase (ache) and butyrylcholinesterase (bche) are enzymes that break down and reduce the level of the neurotransmitter acetylcholine (ach). 2024-02-10 2024-02-12 Not clear
F Javier Luque, Diego Muñoz-Torrer. Acetylcholinesterase: A Versatile Template to Coin Potent Modulators of Multiple Therapeutic Targets. Accounts of chemical research. 2024-02-09. PMID:38333993. conspectusthe enzyme acetylcholinesterase (ache) hydrolyzes the neurotransmitter acetylcholine (ach) at cholinergic synapses of the peripheral and central nervous system. 2024-02-09 2024-02-11 human
Jia Liu, Wei Ha, Eshbakova Komila Alibekovna, Rui Ma, Yan-Ping Sh. Ruptured organosilica nanocapsules immobilized acetylcholinesterase coupled with MnO Nanoscale. 2023-10-20. PMID:37860933. inhibiting ache is a common strategy for reducing the degradation of neurotransmitter acetylcholine, in order to treat early-stage ad. 2023-10-20 2023-11-08 Not clear
Zainabu Majid, Qi Zhang, Zhansen Yang, Huilian Che, Nan Chen. A Multi-Enzyme Cascade Response for the Colorimetric Recognition of Organophosphorus Pesticides Utilizing Core-Shell Pd@Pt Nanoparticles with High Peroxidase-like Activity. Foods (Basel, Switzerland). vol 12. issue 17. 2023-09-09. PMID:37685251. their limits are closely monitored since their residual hinders the capability of acetylcholinesterase (ache) and brings out a threatening accumulation of the neurotransmitter acetylcholine (ach), which affects human well-being. 2023-09-09 2023-10-07 human
Dane Sands, Andrew Davis, Scott Banfield, Ian R Pottie, Sultan Darves. Solvents and detergents compatible with enzyme kinetic studies of cholinesterases. Chemico-biological interactions. 2023-08-14. PMID:37579937. acetylcholinesterase (ache) and butyrylcholinesterase (bche) are enzymes that serve a wide range of physiological functions including the hydrolysis of the neurotransmitter acetylcholine and several other xenobiotics. 2023-08-14 2023-09-07 Not clear
Ana Matošević, Dejan M Opsenica, Marta Spasić, Nikola Maraković, Antonio Zandona, Suzana Žunec, Marija Bartolić, Zrinka Kovarik, Anita Bosa. Evaluation of 4-aminoquinoline derivatives with an n-octylamino spacer as potential multi-targeting ligands for the treatment of Alzheimer's disease. Chemico-biological interactions. 2023-07-05. PMID:37406982. the most successful therapeutic strategy in the treatment of alzheimer's disease (ad) is directed toward increasing levels of the neurotransmitter acetylcholine (ach) by inhibition of acetylcholinesterase (ache) and butyrylcholinesterase (bche), the enzymes responsible for its hydrolysis. 2023-07-05 2023-08-14 human
Archisman Mahapatra, Priya Gupta, Anjali Suman, Shubhendu Shekhar Ray, Guilherme Malafaia, Rahul Kumar Sing. Unraveling the mechanisms of perfluorooctanesulfonic acid-induced dopaminergic neurotoxicity and microglial activation in developing zebrafish. The Science of the total environment. 2023-05-12. PMID:37172847. furthermore, ache activity and dopamine content at the neurotransmitter level were also disrupted after pfos exposure. 2023-05-12 2023-08-14 zebrafish
Qing Yang, Ping Deng, Dan Xing, Haoling Liu, Fang Shi, Lian Hu, Xi Zou, Hongyan Nie, Junli Zuo, Zimeng Zhuang, Meiqi Pan, Juan Chen, Guangyu L. Developmental Neurotoxicity of Difenoconazole in Zebrafish Embryos. Toxics. vol 11. issue 4. 2023-04-28. PMID:37112580. furthermore, the expression of genes involved in neurodevelopment was remarkably altered, which corresponded with the alterations of neurotransmitter content and ache activity. 2023-04-28 2023-08-14 zebrafish
Ping Ding, Chongdan Xiang, Xintong Li, Haibo Chen, Xiaoxia Shi, Xin Li, Chushan Huang, Yunjiang Yu, Jianying Qi, Adela Jing Li, Lijuan Zhang, Guocheng H. Photoaged microplastics induce neurotoxicity via oxidative stress and abnormal neurotransmission in zebrafish larvae (Danio rerio). The Science of the total environment. 2023-04-17. PMID:37068667. similarly, exposure to p-ps significantly increased neurotransmitter (5-ht, gaba, da, and ach) levels and activity of ache, chat, and che. 2023-04-17 2023-08-14 cat
Wenchao Wang, Huijuan Zhang, Luting Wei, Yi Ma, Huiling Jiang, Calista N T Yuen, Jihui Zhang, Hailong Wu, Yilin Sh. Microcystin-leucine arginine causes brain injury and functional disorder in Lithobates catesbeianus tadpoles by oxidative stress and inflammation. Aquatic toxicology (Amsterdam, Netherlands). vol 258. 2023-03-29. PMID:36989925. in the hippocampal and hypothalamic regions, the number of vacuolated neuropils increased with increasing mc-lr exposure concentration, while the expression of genes associated with neuronal development (lgals1, cacna2d2, and nlgn4x) and neurotransmitter transmission (slc6a13 and ache) was significantly down-regulated. 2023-03-29 2023-08-14 Not clear
Abdussamat Güze. Relationship Between Phenolic Content Determined by LC-MS/MS and Antioxidant Capacity and Enzyme Inhibition of Cyclotrichium Niveum L. Chemistry & biodiversity. 2023-03-09. PMID:36891984. the phytochemical composition of the plant, inhibition of acetylcholinesterase (ache) (which hydrolyzes the neurotransmitter acetylcholine), inhibition of paraoxonase for antiatherosclerotic activity (hpon 1) (which detoxifies organophosphates), and antioxidant capacity of this plant. 2023-03-09 2023-08-14 Not clear
Christina Rabeler, TaiXi Gong, Danielle Ireland, Olivier Cochet-Escartin, Eva-Maria S Collin. Acetylcholinesterase Activity Staining in Freshwater Planarians. Current protocols. vol 3. issue 2. 2023-02-17. PMID:36799654. the serine hydrolase acetylcholinesterase (ache) is an important neuronal enzyme which catalyzes the hydrolysis of the neurotransmitter acetylcholine and other choline esters. 2023-02-17 2023-08-14 Not clear
Aso Hameed Hasan, Sonam Shakya, Faiq H S Hussain, Sankaranarayanan Murugesan, Subhash Chander, Mohammad Rizki Fadhil Pratama, Shajarahtunnur Jamil, Basundhara Das, Subhrajit Biswas, Joazaizulfazli Jamali. Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybrids. Journal of biomolecular structure & dynamics. 2023-01-02. PMID:36591704. the major enzyme responsible for the hydrolytic breakdown of the neurotransmitter acetylcholine (ach) is acetylcholinesterase (ache). 2023-01-02 2023-08-14 Not clear
Jeremy Neylon, Jarrad N Fuller, Chris van der Poel, Jarrod E Church, Sebastian Dworki. Organophosphate Insecticide Toxicity in Neural Development, Cognition, Behaviour and Degeneration: Insights from Zebrafish. Journal of developmental biology. vol 10. issue 4. 2022-11-22. PMID:36412643. organophosphate (op) insecticides are used to eliminate agricultural threats posed by insects, through inhibition of the neurotransmitter acetylcholinesterase (ache). 2022-11-22 2023-08-14 zebrafish
Xumin Lin, Yixi Zhang, Baojun Yang, Lingchun Zhang, Yunru Chen, Zewen Li. Multiple acetylcholinesterases in Pardosa pseudoannulata brain worked collaboratively to provide protection from organophosphorus insecticides. Ecotoxicology and environmental safety. vol 248. 2022-11-21. PMID:36410143. acetylcholinesterase (ache) is an essential neurotransmitter hydrolase in nervous systems of animals and its number varies among species. 2022-11-21 2023-08-14 spider
Nancy D Asen, Ogadimma D Okagu, Chibuike C Udenigwe, Rotimi E Aluk. Frontiers in nutrition. vol 9. 2022-11-07. PMID:36337665. compounds with structural similarities to the neurotransmitter (acetylcholine) are mostly used to inhibit the activity of acetylcholinesterase (ache) in alzheimer's disease (ad) therapy. 2022-11-07 2023-08-14 Not clear
Xue Li, Xinjun Liao, Chao Chen, Li Zhang, Sujie Sun, Mengqi Wan, Jieping Liu, Ling Huang, Dou Yang, Hongmei Hu, Xiaoyin Ma, Zilin Zhong, Fasheng Liu, Guanghua Xiong, Huiqiang Lu, Jianjun Chen, Zigang Ca. Propranolol hydrochloride induces neurodevelopmental toxicity and locomotor disorders in zebrafish larvae. Neurotoxicology. vol 93. 2022-11-07. PMID:36341947. additionally, exposure to propranolol hydrochloride could induce oxidative stress, alter the activities of ache and atpase, and disrupt the expression of genes involved in neurodevelopment and neurotransmitter pathways. 2022-11-07 2023-08-14 zebrafish
Jeyaraj Jeyavani, Ashokkumar Sibiya, Narayanan Gopi, Shahid Mahboob, Khalid A Al-Ghanim, Fahad Al-Misned, Zubair Ahmed, Mian Nadeem Riaz, Balasubramanian Palaniappan, Marimuthu Govindarajan, Baskaralingam Vaseehara. Ingestion and impacts of water-borne polypropylene microplastics on Daphnia similis. Environmental science and pollution research international. 2022-09-22. PMID:36136182. additionally, the amount of the neurotransmitter enzyme acetylcholinesterase (ache) activity was decreased. 2022-09-22 2023-08-14 cat
Farida Begum, Najeeb Ur Rehman, Ajmal Khan, Sajid Iqbal, Rehan Zafar Paracha, Jalal Uddin, Ahmed Al-Harrasi, Muhammad Arif Lodh. 2-Mercaptobenzimidazole clubbed hydrazone for Alzheimer's therapy: Frontiers in pharmacology. vol 13. 2022-09-05. PMID:36059999. it is a multifactorial disease, developed by the breakdown of the neurotransmitter acetylcholine via acetylcholinesterase (ache). 2022-09-05 2023-08-14 Not clear