| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J J Buccafusco, R S Aronsta. Clonidine protection from the toxicity of soman, an organophosphate acetylcholinesterase inhibitor, in the mouse. The Journal of pharmacology and experimental therapeutics. vol 239. issue 1. 1986-11-17. PMID:3761196. |
the protective effects of clonidine are likely to involve multiple effects, including blockade of acetylcholine release and postsynaptic muscarinic receptors and transient inhibition of acetylcholinesterase. |
1986-11-17 |
2023-08-11 |
mouse |
| L Barenghi, F Ceriotti, M Luzzana, M Ripamonti, A Mosca, P A Bonin. Measurement of erythrocyte acetylcholinesterase and plasma cholinesterase activity by a differential pH technique. Annals of clinical biochemistry. vol 23 ( Pt 5). 1986-11-13. PMID:3767290. |
we describe a new electrochemical method for the determination of erythrocyte acetylcholinesterase activity (ec 3.1.1.7) and plasma cholinesterase (ec 3.1.1.8) activity, based on the measurements of ph variation due to release of acetic acid from acetylcholine. |
1986-11-13 |
2023-08-11 |
Not clear |
| L Mazzanti, A Pastuszko, G Lena. Effects of ketamine anesthesia on rat-brain membranes: fluidity changes and kinetics of acetylcholinesterase. Biochimica et biophysica acta. vol 861. issue 1. 1986-10-31. PMID:3756149. |
changes in acetylcholinesterase activity, with a decrease in vmax and no change in the km for acetylcholine, closely follow the fluidity increase. |
1986-10-31 |
2023-08-11 |
Not clear |
| H A Berman, M M Decke. Kinetic, equilibrium and spectroscopic studies on cation association at the active center of acetylcholinesterase: topographic distinction between trimethyl and trimethylammonium sites. Biochimica et biophysica acta. vol 872. issue 1-2. 1986-09-17. PMID:3089281. |
this study examines the importance of electrostatic interactions on ligand association at the active center of acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7). |
1986-09-17 |
2023-08-11 |
Not clear |
| J Willoughby, S A Harvey, J B Clar. Compartmentation and regulation of acetylcholine synthesis at the synapse. The Biochemical journal. vol 235. issue 1. 1986-09-17. PMID:3091003. |
under sub-optimal glucose concentrations or in the absence of treatment of the synaptosomes with the acetylcholinesterase inhibitor phospholine, the incorporation of radioactivity exceeded total synthesis, indicating that cycling between acetylcholine and its precursors may occur. |
1986-09-17 |
2023-08-11 |
Not clear |
| D F Sharman, T R Coope. A semi-automated fluorimetric method for measuring acetylcholinesterase activity in small volumes of cerebrospinal fluid and tissue extracts using acetylcholine as substrate. Journal of neuroscience methods. vol 16. issue 4. 1986-09-17. PMID:3736119. |
a semi-automated fluorimetric method for measuring acetylcholinesterase activity in small volumes of cerebrospinal fluid and tissue extracts using acetylcholine as substrate. |
1986-09-17 |
2023-08-11 |
Not clear |
| D F Sharman, T R Coope. A semi-automated fluorimetric method for measuring acetylcholinesterase activity in small volumes of cerebrospinal fluid and tissue extracts using acetylcholine as substrate. Journal of neuroscience methods. vol 16. issue 4. 1986-09-17. PMID:3736119. |
a fluorimetric method for the assay of acetylcholinesterase (ache; ec 3.1.1.7) in tissue extracts and cerebrospinal fluid, using acetylcholine as the substrate, is described. |
1986-09-17 |
2023-08-11 |
Not clear |
| O S Sotnikov, A A Alie. [Ultrastructural changes in the autonomic interneuronal synapse during activation in the presence of acetylcholinesterase suppression]. Arkhiv anatomii, gistologii i embriologii. vol 90. issue 5. 1986-09-16. PMID:3017272. |
structural-functional reconstructions of the frog autonomic interneuronal synapsis have been studied at its activation with endogenic acetylcholine under conditions of acetylcholinesterase suppression. |
1986-09-16 |
2023-08-11 |
Not clear |
| A Goldlust, R Arnon, I Silman, R Tarrab-Hazda. Acetylcholinesterase of Schistosoma mansoni: purification and characterization. Journal of neuroscience research. vol 15. issue 4. 1986-08-06. PMID:3723610. |
larval acetylcholinesterase (acetylcholine acetylhydrolase) ec 3.1.3.7 of the trematode schistosoma mansoni was characterized and purified by affinity chromatography. |
1986-08-06 |
2023-08-11 |
Not clear |
| E Aizenman, G G Bierkamper, E F Stanle. Botulinum toxin prevents stimulus-induced backfiring produced by neostigmine in the mouse phrenic nerve-diaphragm. The Journal of physiology. vol 372. 1986-07-25. PMID:3014126. |
our results support the hypothesis that the effects of neostigmine on the motoneurone terminal are mediated by the prolonged action of acetylcholine that occurs with inhibition of acetylcholinesterase. |
1986-07-25 |
2023-08-11 |
mouse |
| J Weston, S A Greenfiel. Release of acetylcholinesterase in the rat nigrostriatal pathway: relation to receptor activation and firing rate. Neuroscience. vol 17. issue 4. 1986-07-16. PMID:3714040. |
thus, application of acetylcholine into the substantia nigra induced an increase, while apomorphine induced a decrease in the release of acetylcholinesterase from the striatum. |
1986-07-16 |
2023-08-11 |
rat |
| J Weston, S A Greenfiel. Release of acetylcholinesterase in the rat nigrostriatal pathway: relation to receptor activation and firing rate. Neuroscience. vol 17. issue 4. 1986-07-16. PMID:3714040. |
however, in the substantia nigra, the release of acetylcholinesterase did not follow this pattern: acetylcholine reduced local release, while apomorphine caused no change. |
1986-07-16 |
2023-08-11 |
rat |
| N A Do Thi, C Bon, H L Koenig, J M Bourr. Acetylcholine receptors and acetylcholinesterase activity in soleus muscle of trembler dysmyelinating mutant: a cytochemical and biochemical analysis. Neuroscience letters. vol 65. issue 1. 1986-06-09. PMID:3010196. |
acetylcholine receptors and acetylcholinesterase activity in soleus muscle of trembler dysmyelinating mutant: a cytochemical and biochemical analysis. |
1986-06-09 |
2023-08-11 |
Not clear |
| N P Stimler-Gerar. Parasympathetic stimulation as a mechanism for platelet-activating factor-induced contractile responses in the lung. The Journal of pharmacology and experimental therapeutics. vol 237. issue 1. 1986-05-15. PMID:3958964. |
in the presence of physostigmine, an acetylcholinesterase inhibitor, the paf-induced contractions of lung strips were modestly enhanced, consistent with release of endogenous acetylcholine. |
1986-05-15 |
2023-08-11 |
Not clear |
| T Kita, T Hata, T Higashiguchi, E Itoh, A Kawabat. Changes of total acetylcholine content and the activity of related enzymes in SART (repeated cold)-stressed rat brain and duodenum. Japanese journal of pharmacology. vol 40. issue 1. 1986-05-15. PMID:3959351. |
in sart-stressed rats regarded as pathologically diseased model animals with vagotonic-type autonomic imbalance, a decrease of total acetylcholine (t-ach) content and enhancements of choline acetyltransferase (cat) and acetylcholinesterase (ache) activities were recognized in the basal ganglia and hypothalamus. |
1986-05-15 |
2023-08-11 |
rat |
| J Longmore, B Jani, C M Bradshaw, E Szabad. Effects of locally administered anticholinesterase agents on the secretory response of human eccrine sweat glands to acetylcholine and carbachol. British journal of clinical pharmacology. vol 21. issue 2. 1986-05-07. PMID:3954930. |
the difference in the time-course of responses to acetylcholine and carbachol may be attributed to differences in the susceptibility of the two drugs to metabolism by acetylcholinesterase; carbachol, unlike acetylcholine, being virtually immune to metabolism by this enzyme. |
1986-05-07 |
2023-08-11 |
human |
| W Liu, C L Tso. Determination of rate constants for the irreversible inhibition of acetylcholine esterase by continuously monitoring the substrate reaction in the presence of the inhibitor. Biochimica et biophysica acta. vol 870. issue 2. 1986-05-02. PMID:3955054. |
the kinetics of the irreversible inhibition of acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) by diisopropyl fluorophosphate and paraoxon have been studied by the approach of following the substrate reaction continuously in the presence of both the substrate and the inhibitor based on kinetic equations previously derived (tsou, c.-l. (1965) acta biochim. |
1986-05-02 |
2023-08-11 |
Not clear |
| E B Fishman, G C Siek, R D MacCallum, E D Bird, L Volicer, J K Marqui. Distribution of the molecular forms of acetylcholinesterase in human brain: alterations in dementia of the Alzheimer type. Annals of neurology. vol 19. issue 3. 1986-04-28. PMID:3963769. |
acetylcholinesterase (ache), the enzyme that degrades acetylcholine, is a heterogeneous enzyme that can be separated into multiple molecular forms. |
1986-04-28 |
2023-08-11 |
human |
| M M Fathi, A M Asaa. Effect of thiopental sodium and barbitone sodium on the total acetylcholine content and acetylcholinesterase activity in the brain tissue of Arvicanthis niloticus. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 83. issue 1. 1986-04-25. PMID:2869896. |
effect of thiopental sodium and barbitone sodium on the total acetylcholine content and acetylcholinesterase activity in the brain tissue of arvicanthis niloticus. |
1986-04-25 |
2023-08-11 |
Not clear |
| B G Wallac. Aggregating factor from Torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase, and butyrylcholinesterase on cultured myotubes. The Journal of cell biology. vol 102. issue 3. 1986-04-15. PMID:3949878. |
aggregating factor from torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase, and butyrylcholinesterase on cultured myotubes. |
1986-04-15 |
2023-08-11 |
Not clear |