| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L L Rubi. Increases in muscle Ca2+ mediate changes in acetylcholinesterase and acetylcholine receptors caused by muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 20. 1985-11-18. PMID:2996006. |
increases in muscle ca2+ mediate changes in acetylcholinesterase and acetylcholine receptors caused by muscle contraction. |
1985-11-18 |
2023-08-11 |
rat |
| L L Rubi. Increases in muscle Ca2+ mediate changes in acetylcholinesterase and acetylcholine receptors caused by muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 20. 1985-11-18. PMID:2996006. |
the synthesis of acetylcholinesterase (acchoe; acetylcholine acetylhydrolase, ec 3.1.1.7) and of acetylcholine receptors (acchor) by cultured rat muscle fibers is influenced strongly by the level of muscle contractile activity. |
1985-11-18 |
2023-08-11 |
rat |
| G Damsma, B H Westerink, A S Hor. A simple, sensitive, and economic assay for choline and acetylcholine using HPLC, an enzyme reactor, and an electrochemical detector. Journal of neurochemistry. vol 45. issue 5. 1985-11-18. PMID:4045469. |
the method is based on a separation of choline and acetylcholine by cation exchange hplc followed by passage of the effluent through a postcolumn reactor containing a mixture of acetylcholinesterase and choline oxidase; the latter enzyme converts choline to betaine and hydrogen peroxide, the former enzyme hydrolyzes acetylcholine to acetate and choline. |
1985-11-18 |
2023-08-11 |
Not clear |
| A Shahar, A Mizrahi, S Reuveny, T Zinman, A Shainber. Differentiation of myoblasts with nerve cells on microcarriers in culture. Developments in biological standardization. vol 60. 1985-11-14. PMID:3899788. |
cells within the conglomerates fused to form myotubes which synthesized muscle-specific proteins such as: creatine kinase, acetylcholinesterase, acetylcholine receptors, and contracted in response to electrical stimulation. |
1985-11-14 |
2023-08-11 |
rat |
| L Anglister, U J McMaha. Basal lamina directs acetylcholinesterase accumulation at synaptic sites in regenerating muscle. The Journal of cell biology. vol 101. issue 3. 1985-10-09. PMID:3875617. |
at the regenerated neuromuscular junctions, as at the original ones, the muscle fibers are characterized by junctional folds and accumulations of acetylcholine receptors and acetylcholinesterase (ache). |
1985-10-09 |
2023-08-11 |
Not clear |
| N Kaneda, T Nagats. Highly sensitive assay for choline acetyltransferase activity by high-performance liquid chromatography with electrochemical detection. Journal of chromatography. vol 341. issue 1. 1985-09-23. PMID:4019691. |
this assay method is based on the separation of acetylcholine and choline on a develosil ph-5 reversed-phase column (a phenyl column), followed by their enzymatic conversion to hydrogen peroxide through post-column reaction with acetylcholinesterase and choline oxidase. |
1985-09-23 |
2023-08-11 |
rat |
| L Eder-Colli, S Amat. Membrane-bound choline acetyltransferase in Torpedo electric organ: a marker for synaptosomal plasma membranes? Neuroscience. vol 15. issue 2. 1985-09-17. PMID:4022340. |
an enrichment was also observed for another cholinergic marker, the enzyme acetylcholinesterase, but not for the nicotinic receptor to acetylcholine, a marker for postsynaptic membranes. |
1985-09-17 |
2023-08-11 |
human |
| M H Gelb, J P Svaren, R H Abele. Fluoro ketone inhibitors of hydrolytic enzymes. Biochemistry. vol 24. issue 8. 1985-09-16. PMID:2990541. |
the acetylcholine analogues 6,6-dimethyl-1,1,1-trifluoro-2-heptanone and 3,3-difluoro-6,6-dimethyl-2-heptanone are inhibitors of acetylcholinesterase with ki values of 16 x 10(-9) m and 1.6 x 10(-9) m, respectively. |
1985-09-16 |
2023-08-11 |
Not clear |
| K Akuzawa, K Wakabayash. A serum-free culture of the neurons in the septal, preoptic, and hypothalamic region. Effects of triiodothyronine and estradiol. Endocrinologia japonica. vol 32. issue 1. 1985-09-04. PMID:4017971. |
effects of triiodothyronine (t3) and estradiol (e2) on the activities of choline acetyltransferase (chat) and acetylcholinesterase (ache), synthetic and degradative enzymes for acetylcholine, respectively, were examined in this culture. |
1985-09-04 |
2023-08-11 |
rat |
| H Zakut, A Matzkel, E Schejter, A Avni, H Sore. Polymorphism of acetylcholinesterase in discrete regions of the developing human fetal brain. Journal of neurochemistry. vol 45. issue 2. 1985-08-20. PMID:4009167. |
the molecular forms and membrane association of acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) and pseudocholinesterase (acylcholine acylhydrolase, ec 3.1.1.8) were determined in the presence of protease inhibitors in dissected regions of developing human fetal brain, as compared with parallel areas from mature brain. |
1985-08-20 |
2023-08-11 |
human |
| H Zakut, A Matzkel, E Schejter, A Avni, H Sore. Polymorphism of acetylcholinesterase in discrete regions of the developing human fetal brain. Journal of neurochemistry. vol 45. issue 2. 1985-08-20. PMID:4009167. |
two major forms of acetylcholinesterase activity, sedimenting at 10-11s and 4-5s, respectively, were detected on sucrose gradients and possessed similar catalytic properties, as judged by their individual km values toward [3h]acetylcholine (ca. |
1985-08-20 |
2023-08-11 |
human |
| B G Wallace, R M Nitkin, N E Reist, J R Fallon, N N Moayeri, U J McMaha. Aggregates of acetylcholinesterase induced by acetylcholine receptor-aggregating factor. Nature. vol 315. issue 6020. 1985-08-01. PMID:4010772. |
aggregates of acetylcholinesterase induced by acetylcholine receptor-aggregating factor. |
1985-08-01 |
2023-08-11 |
Not clear |
| L A Piruzian, M R Mukumov, L V Sorokin, N M Afanas'ev. [Effect of prodigiozan and pyrogenal on the neural regulation of the frog heart]. Farmakologiia i toksikologiia. vol 48. issue 2. 1985-07-18. PMID:3873353. |
the bacterial lipopolysaccharides did not alter acetylcholinesterase activity or myocardial sensitivity to acetylcholine. |
1985-07-18 |
2023-08-11 |
Not clear |
| S Guimarães, M Q Paiva, D Moura, J Proenç. The saturability of a site of loss and the degree of supersensitivity to agonists which are substrates of this site of loss. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 1. 1985-07-08. PMID:2860569. |
the influence of inhibition of neuronal uptake by cocaine on the alpha-adrenoceptor-mediated effect of noradrenaline was studied on the dog saphenous vein; the influence of inhibition of comt by u-0521 on the beta-adrenoceptor-mediated effect of isoprenaline was studied on the dog saphenous vein and on the guinea-pig trachea; the influence of inhibition of acetylcholinesterase by physostigmine on the effect of acetylcholine was studied on the guinea-pig ileum. |
1985-07-08 |
2023-08-11 |
dog |
| S Brimijoin, K P Mint. Human acetylcholinesterase. Immunochemical studies with monoclonal antibodies. Biochimica et biophysica acta. vol 828. issue 3. 1985-06-17. PMID:2580561. |
monoclonal antibodies were used to investigate the immunochemistry of human erythrocyte acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7). |
1985-06-17 |
2023-08-11 |
human |
| T Kobayashi, V Askana. Acetylcholine receptors and acetylcholinesterase accumulate at the nerve-muscle contacts of de novo grown human monolayer muscle cocultured with fetal rat spinal cord. Experimental neurology. vol 88. issue 2. 1985-05-28. PMID:3987861. |
acetylcholine receptors and acetylcholinesterase accumulate at the nerve-muscle contacts of de novo grown human monolayer muscle cocultured with fetal rat spinal cord. |
1985-05-28 |
2023-08-11 |
human |
| P Kása, W Dames, Z Rakonczay, K Gulya, F Joó, J R Wolf. Modulation of the acetylcholine system in the superior cervical ganglion of rat: effects of GABA and hypoglossal nerve implantation after in vivo GABA treatment. Journal of neurochemistry. vol 44. issue 5. 1985-05-28. PMID:3989534. |
this treatment reduced the acetylcholinesterase (ache; ec 3.1.1.7) activity by 30% (p less than 0.01) and transiently increased the number of nicotinic acetylcholine receptors, but had no significant effect on the choline acetyltransferase (acetyl-coenzyme a:choline-o-acetyltransferase; ec 2.3.1.6) activity, the ach level, or the number of muscarinic acetylcholine receptors. |
1985-05-28 |
2023-08-11 |
rat |
| H Soreq, D Zevin-Sonkin, A Avni, L M Hall, P Spiere. A human acetylcholinesterase gene identified by homology to the Ace region of Drosophila. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 6. 1985-05-03. PMID:3856864. |
the ace locus of the drosophila genome controls biosynthesis of the neurotransmitter-hydrolyzing enzyme acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7). |
1985-05-03 |
2023-08-11 |
human |
| T P Kenakin, D Bee. Self-cancellation of drug properties as a mode of organ selectivity: the antimuscarinic effects of ambenonium. The Journal of pharmacology and experimental therapeutics. vol 232. issue 3. 1985-04-25. PMID:2857786. |
ambenonium was a less potent antagonist of tissue responses to acetylcholine, and the underestimation in the pkb (as compared to that obtained with bethanechol) could be eliminated by prior treatment of tissues with the acetylcholinesterase inhibitor neostigmine. |
1985-04-25 |
2023-08-11 |
rat |
| M L Kirby, R S Aronstam, J J Buccafusc. Changes in cholinergic parameters associated with failure of conotruncal septation in embryonic chick hearts after neural crest ablation. Circulation research. vol 56. issue 3. 1985-04-22. PMID:3971512. |
a disruption of parasympathetic innervation was indicated by: (1) a decrease in acetylcholinesterase staining, (2) a decrease (27%) in the number of ganglion cells in the conotruncus, (3) decreases in the acetylcholine content of atrium (31%) and ventricle (39%), and (4) a decrease (21%) in muscarinic acetylcholine receptor density on incubation day 15. |
1985-04-22 |
2023-08-11 |
chicken |