| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H C Froede, I B Wilso. Direct determination of acetyl-enzyme intermediate in the acetylcholinesterase-catalyzed hydrolysis of acetylcholine and acetylthiocholine. The Journal of biological chemistry. vol 259. issue 17. 1984-10-05. PMID:6469995. |
acetylcholinesterase from electrophorus electricus was acetylated during the hydrolysis of [3h]acetylcholine and [3h]acetylthiocholine. |
1984-10-05 |
2023-08-12 |
Not clear |
| M Eco. The location of neuromuscular junctions on regenerating adult mouse muscle in culture. Journal of the neurological sciences. vol 64. issue 2. 1984-08-27. PMID:6747664. |
the position of the original motor end-plates on the explanted muscle fibres was determined by using either rhodamine-labelled alpha-bungarotoxin (r alpha bt) binding to the acetylcholine receptors, or by stains to demonstrate acetylcholinesterase (ache) also located at the end-plate. |
1984-08-27 |
2023-08-12 |
mouse |
| A L Acheson, K Naujoks, H Thoene. Nerve growth factor-mediated enzyme induction in primary cultures of bovine adrenal chromaffin cells: specificity and level of regulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 4. issue 7. 1984-08-20. PMID:6145760. |
acetylcholinesterase (ache), an enzyme which catalyzes the breakdown of acetylcholine, is also induced by ngf. |
1984-08-20 |
2023-08-12 |
cattle |
| J Jedrzejczyk, I Silman, J Lai, E A Barnar. Molecular forms of acetylcholinesterase in synaptic and extrasynaptic regions of avian tonic muscle. Neuroscience letters. vol 46. issue 3. 1984-08-17. PMID:6738921. |
acetylcholinesterase is functional at tonic fibre endplates, but the absence of the collagen-tailed form may account for the lower efficiency of the enzymic removal of acetylcholine there. |
1984-08-17 |
2023-08-12 |
chicken |
| M Rainer. Histochemical investigations of Rotifera Bdelloidea. I. Localization of cholinesterase activity. The Histochemical journal. vol 16. issue 6. 1984-08-13. PMID:6735744. |
the effects in vivo of cholinesterase inhibitors, as well as those of tubocurarin, bungarotoxin and acetylcholine, are consistent with the histochemical results, indicating a cholinergic system of transmission and acetylcholinesterase, as well as butyrylcholinesterase, activity. |
1984-08-13 |
2023-08-12 |
Not clear |
| E M Volkov, V N Frosi. [Non-quantum release of acetylcholine from motor nerve endings and denervation changes in muscle fiber membranes in the rat following blockade of axonal transport]. Neirofiziologiia = Neurophysiology. vol 16. issue 2. 1984-07-27. PMID:6204213. |
the size of non-quantal acetylcholine secretion was estimated by the amplitude of muscle membrane hyperpolarisation in the presence of curare in solution after preliminary acetylcholinesterase inhibition with armin. |
1984-07-27 |
2023-08-12 |
rat |
| L L Seelig, P Doody, L Brainard, J S Gidda, R K Goya. Acetylcholinesterase and choline acetyltransferase staining of neurons in the opossum esophagus. The Anatomical record. vol 209. issue 1. 1984-07-20. PMID:6203439. |
the purpose of the present investigation was to identify and compare cholinergic intramural neurons in the lower esophageal sphincter and esophageal body by histochemical staining for acetylcholinesterase and the enzyme that synthesizes acetylcholine, choline acetyltransferase. |
1984-07-20 |
2023-08-12 |
Not clear |
| M L Gilberstadt, J A Russel. Determination of picomole quantities of acetylcholine and choline in physiologic salt solutions. Analytical biochemistry. vol 138. issue 1. 1984-07-20. PMID:6731854. |
dried pellets of unlabeled choline and acetylcholine standards were assayed radioenzymatically using [gamma-32p]atp, choline kinase, and acetylcholinesterase. |
1984-07-20 |
2023-08-12 |
Not clear |
| K Gulya, D Budai, P Kása, Z Rakoncza. In vivo effects of beta-bungarotoxin on the acetylcholine system in different brain areas of the rat. Journal of neurochemistry. vol 43. issue 1. 1984-07-19. PMID:6726239. |
in animals treated with the same dose three times, on the first, third, and fifth days, and sacrificed 2 days after the last injection, the choline acetyltransferase and acetylcholinesterase activities were reduced and the number of muscarinic acetylcholine receptors was decreased. |
1984-07-19 |
2023-08-12 |
rat |
| N Razon, H Soreq, E Roth, A Bartal, I Silma. Characterization of activities and forms of cholinesterases in human primary brain tumors. Experimental neurology. vol 84. issue 3. 1984-07-10. PMID:6723888. |
in both normal forebrain and meningiomas, acetylcholinesterase (acetylcholine hydrolase; ec 3.1.1.7) accounted for almost all the cholinesterase activity, but in almost all gliomas elevated pseudocholinesterase (acylcholine acylhydrolase; ec 3.1.1.8) could be detected. |
1984-07-10 |
2023-08-12 |
human |
| E X Albuquerque, A Akaike, K P Shaw, D L Ricket. The interaction of anticholinesterase agents with the acetylcholine receptor-ionic channel complex. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 4. issue 2 Pt 2. 1984-07-09. PMID:6327444. |
the actions of pyridostigmine (pyr), a quaternary carbamate compound, and physostigmine ( phy ), a tertiary carbamate, both known for their reversible inhibition of acetylcholinesterase (ache), were studied on the electrically excitable membrane and acetylcholine (ach) receptor of the frog cutaneous pectoris, sartorius, and interosseal muscles, as well as the chronically denervated soleus muscle of the rat and myoballs from neonatal rats. |
1984-07-09 |
2023-08-12 |
rat |
| S Garattini, G L Forloni, S Tirelli, H Ladinsky, S Consol. Neurochemical effects of minaprine, a novel psychotropic drug, on the central cholinergic system of the rat. Psychopharmacology. vol 82. issue 3. 1984-05-30. PMID:6425901. |
by contrast, the increase in striatal acetylcholine appeared after 30 min when there was no longer inhibition of acetylcholinesterase activity and when the level of minaprine in brain was reduced by 78%. |
1984-05-30 |
2023-08-12 |
rat |
| J G Clement, H T Copema. Soman and sarin induce a long-lasting naloxone-reversible analgesia in mice. Life sciences. vol 34. issue 15. 1984-05-23. PMID:6708739. |
it is suggested that the organophosphate-induced analgesia is due to a combination of an increased concentration of acetylcholine due to inhibition of acetylcholinesterase combined with a reduced destruction of endogenous opioid-like substances due to organophosphate inhibition of proteases. |
1984-05-23 |
2023-08-12 |
mouse |
| M C Olianas, P Onali, J P Schwartz, N H Neff, E Cost. The muscarinic receptor adenylate cyclase complex of rat striatum: desensitization following chronic inhibition of acetylcholinesterase activity. Journal of neurochemistry. vol 42. issue 5. 1984-05-17. PMID:6142926. |
chronic inhibition of acetylcholinesterase activity by treatment with diisopropylfluorophosphate (dfp) decreased the capacity of acetylcholine (ach) acting at a muscarinic receptor to inhibit basal adenylate cyclase activity in homogenates from rat striatum. |
1984-05-17 |
2023-08-12 |
rat |
| M Gupta, G K Bagchi, S D Gupta, D Sasmal, T Chatterjee, S N De. Changes of acetylcholine, catecholamines and amino acid in mice brain following treatment with Nuvacron and Furadan. Toxicology. vol 30. issue 2. 1984-05-11. PMID:6710541. |
the following were measured: acetylcholine, acetylcholinesterase, gamma-aminobutyric acid, epinephrine, norepinephrine, dopamine and 5-hydroxytryptamine. |
1984-05-11 |
2023-08-12 |
mouse |
| M Gupta, G K Bagchi, S D Gupta, D Sasmal, T Chatterjee, S N De. Changes of acetylcholine, catecholamines and amino acid in mice brain following treatment with Nuvacron and Furadan. Toxicology. vol 30. issue 2. 1984-05-11. PMID:6710541. |
these pesticides caused a significant decrease in acetylcholinesterase activity and a significant increase in acetylcholine, gamma-amino-butyric acid, epinephrine, norepinephrine, dopamine and 5-hydroxy tryptamine concentrations. |
1984-05-11 |
2023-08-12 |
mouse |
| R L Rotund. Asymmetric acetylcholinesterase is assembled in the Golgi apparatus. Proceedings of the National Academy of Sciences of the United States of America. vol 81. issue 2. 1984-03-23. PMID:6582503. |
the synthesis, assembly, and processing of the multiple molecular forms of acetylcholinesterase (acchoease; acetylcholine acetylhydrolase, ec 3.1.1.7) in quail muscle cultures was studied by using lectins to distinguish enzyme molecules residing in different subcellular compartments. |
1984-03-23 |
2023-08-12 |
Not clear |
| I W Chubb, E Ranieri, G H White, A J Hodgso. The enkephalins are amongst the peptides hydrolyzed by purified acetylcholinesterase. Neuroscience. vol 10. issue 4. 1984-03-23. PMID:6664495. |
the ability of acetylcholinesterase to hydrolyse naturally occurring compounds of different chemical nature, like esters and peptides, may help explain the long-standing puzzle of why the enzyme is more widely distributed than acetylcholine, once thought to be its sole natural substrate. |
1984-03-23 |
2023-08-12 |
Not clear |
| C B Gundersen, R Miled. Acetylcholinesterase activity of Xenopus laevis oocytes. Neuroscience. vol 10. issue 4. 1984-03-23. PMID:6664498. |
cations were found generally to diminish the acetylcholinesterase activity of oocyte homogenates, and lanthanum ions inhibited acetylcholine hydrolysis with an ic50 of 0.63 mm. |
1984-03-23 |
2023-08-12 |
xenopus_laevis |
| K Gulya, P Kás. Structural localization of the elements of the acetylcholine system in the rat cerebellum. Acta biologica Hungarica. vol 34. issue 2-3. 1984-03-14. PMID:6320559. |
the elements of the acetylcholine system (choline acetyltransferase, acetylcholinesterase, acetylcholine receptors) were analysed in the cerebellum of the rat by histochemical and biochemical means. |
1984-03-14 |
2023-08-12 |
rat |