| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Dörner, R Bluth, R Tönje. Acetylcholine concentrations in the developing brain appear to affect emotionality and mental capacity in later life. Acta biologica et medica Germanica. vol 41. issue 7-8. 1983-01-19. PMID:7148280. |
the decreased acetylcholine concentration in the infantile brain as well as the permanent emotional and mental ill-effects, which were produced by neonatal deprivation, could be prevented by neonatal administration of the acetylcholinesterase inhibitor pyridostigmine. |
1983-01-19 |
2023-08-12 |
rat |
| P Kása, K Bánsághy, Z Rakonczay, K Guly. Postnatal development of the acetylcholine system in different parts of the rat cerebellum. Journal of neurochemistry. vol 39. issue 6. 1983-01-07. PMID:7142998. |
the components of the cholinergic nervous system, i.e., choline acetyltransferase, acetylcholinesterase, sodium-dependent high-affinity choline uptake, acetylcholine, and the muscarinic acetylcholine receptors, in the developing archi- and paleocerebellum of the rat have been investigated by biochemical methods. |
1983-01-07 |
2023-08-12 |
rat |
| P Kása, K Bánsághy, Z Rakonczay, K Guly. Postnatal development of the acetylcholine system in different parts of the rat cerebellum. Journal of neurochemistry. vol 39. issue 6. 1983-01-07. PMID:7142998. |
the cholinergic structure develops first in the archicerebellum, which displays high levels of choline acetyltransferase, acetylcholinesterase, acetylcholine, and sodium-dependent high-affinity choline uptake. |
1983-01-07 |
2023-08-12 |
rat |
| P Gomez-Ramos, S Nelson, D Walter, R Cross, F E Samso. Kainic acid alters cholinergic responses in the rat retina: a 2-deoxyglucose study. Journal of neuroscience research. vol 7. issue 3. 1982-12-21. PMID:7131594. |
this responsiveness to acetylcholine may be entirely due to the 80% decrease in acetylcholinesterase in the retina observed 1 week after kainic acid exposure or in part to a supersensitivity of the ganglion cells following the period of acetylcholine depletion. |
1982-12-21 |
2023-08-12 |
rat |
| T R Sharp, T L Rosenberr. A pseudo-first-order kinetic approach to measurement of acetylcholine hydrolysis by acetylcholinesterase. Journal of biochemical and biophysical methods. vol 6. issue 2. 1982-10-21. PMID:7108127. |
a pseudo-first-order kinetic approach to measurement of acetylcholine hydrolysis by acetylcholinesterase. |
1982-10-21 |
2023-08-12 |
Not clear |
| T R Sharp, T L Rosenberr. A pseudo-first-order kinetic approach to measurement of acetylcholine hydrolysis by acetylcholinesterase. Journal of biochemical and biophysical methods. vol 6. issue 2. 1982-10-21. PMID:7108127. |
a continuous spectrophotometric procedure is presented for the measurement of the kinetic properties of acetylcholinesterase (ec 3.1.1.7) with its natural substrate, acetylcholine. |
1982-10-21 |
2023-08-12 |
Not clear |
| B B Hasinof. Kinetics of acetylthiocholine binding to electric eel acetylcholinesterase in glycerol/water solvents of increased viscosity. Evidence for a diffusion-controlled reaction. Biochimica et biophysica acta. vol 704. issue 1. 1982-09-24. PMID:7093289. |
steady-state kinetic studies were made on the very efficient enzyme hydrolysis of acetylthiocholine by electric eel acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) in glycerol/water solvents of increased viscosity. |
1982-09-24 |
2023-08-12 |
Not clear |
| M Quik, M V Lamarc. Blockade of transmission in rat sympathetic ganglia by a toxin which co-purifies with alpha-bungarotoxin. Brain research. vol 238. issue 2. 1982-09-10. PMID:6284299. |
bgt ii-s1 was equipotent in blocking the ganglionic action potential in the presence or absence of eserine; thus, it is not acting as an acetylcholinesterase by increasing acetylcholine breakdown. |
1982-09-10 |
2023-08-12 |
rat |
| F W Boot. Effect of limb immobilization on skeletal muscle. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 52. issue 5. 1982-09-10. PMID:7047468. |
muscles of immobilized limbs have either no change or a decrease in resting membrane potential, an increase in extrajunctional acetylcholine receptors of lesser magnitude than the increase that occurred in denervated muscle, and no change in acetylcholinesterase activity in neuromuscular junctions. |
1982-09-10 |
2023-08-12 |
Not clear |
| F Mizobe, B G Livet. Biphasic effect of eserine and other acetylcholinesterase inhibitors on the nicotinic response to acetylcholine in cultured adrenal chromaffin cells. Journal of neurochemistry. vol 39. issue 2. 1982-08-26. PMID:7086423. |
biphasic effect of eserine and other acetylcholinesterase inhibitors on the nicotinic response to acetylcholine in cultured adrenal chromaffin cells. |
1982-08-26 |
2023-08-12 |
Not clear |
| M Israël, B Lesbat. Application to mammalian tissues of the chemiluminescent method for detecting acetylcholine. Journal of neurochemistry. vol 39. issue 1. 1982-08-07. PMID:7045285. |
the assay can then be performed as previously described (acetylcholinesterase hydrolyses acetylcholine; choline oxidase converts choline to betaine and h2o2, which gives off light in the presence of luminol and peroxidase). |
1982-08-07 |
2023-08-12 |
mouse |
| L H Silver, D J Prescot. Aggregation properties of the acetylcholinesterase from the central nervous system of Manduca sexta. Journal of neurochemistry. vol 38. issue 6. 1982-07-22. PMID:7077334. |
the cns of the tobacco hornworm, manduca sexta, provides a rich source of true acetylcholinesterase (ache, acetylcholine, hydrolase, ec 3.1.1.7). |
1982-07-22 |
2023-08-12 |
Not clear |
| N R Elaev, N M Sudakova, L K Onegin. [Regulation of acetylcholinesterase level in microsomes of neurons by acetylcholine and cyclic nucleotides]. Biulleten' eksperimental'noi biologii i meditsiny. vol 93. issue 1. 1982-06-24. PMID:6279208. |
[regulation of acetylcholinesterase level in microsomes of neurons by acetylcholine and cyclic nucleotides]. |
1982-06-24 |
2023-08-12 |
Not clear |
| T P Rothman, M D Gersho. Phenotypic expression in the developing murine enteric nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 3. 1982-05-27. PMID:7062117. |
synthesis of [3h] acetylcholine ([3h]ach) from [3h]choline and acetylcholinesterase histochemistry were used as phenotypic markers for cholinergic neurons, while the radioautographic detection of the specific uptake of [3h]serotonin (5-[3h]ht) and immunocytochemical staining with antiserum to 5-ht marked serotonergic neurons. |
1982-05-27 |
2023-08-12 |
mouse |
| H Soreq, R Parvari, I Silma. Biosynthesis and secretion of catalytically active acetylcholinesterase in Xenopus oocytes microinjected with mRNA from rat brain and from Torpedo electric organ. Proceedings of the National Academy of Sciences of the United States of America. vol 79. issue 3. 1982-05-21. PMID:6950429. |
a novel technique was developed for monitoring the level of the mrna species that direct the synthesis of acetylcholinesterase (acchoease; acetylcholine acetylhydrolase, ec 3.1.1.7), using microinjected xenopus oocytes as a translation system. |
1982-05-21 |
2023-08-12 |
rat |
| J Villega. Axon/Schwann-cell relationships in the giant nerve fibre of the squid. The Journal of experimental biology. vol 95. 1982-05-21. PMID:7334317. |
thus, the results of the experiments herein discussed revealed that, under physiological conditions: the schwann cell is able to synthesize, store and release acetylcholine; and that it has acetylcholine receptors of the nicotinic type, and acetylcholinesterase enzyme activity in its plasma membrane. |
1982-05-21 |
2023-08-12 |
squid |
| J Villega. Axon/Schwann-cell relationships in the giant nerve fibre of the squid. The Journal of experimental biology. vol 95. 1982-05-21. PMID:7334317. |
on the other hand, the axon has low acetyltransferase activity and acetylcholine concentration in its axoplasm, and a high acetylcholinesterase activity in its axolemma. |
1982-05-21 |
2023-08-12 |
squid |
| M E Fant, R D Harbiso. Syncytiotrophoblast membrane vesicles: a model for examining the human placental cholinergic system. Teratology. vol 24. issue 2. 1982-05-12. PMID:7336361. |
vesicle cholinesterase activity was enriched and had a substrate preference consistent with that of acetylcholinesterase (acetylcholine greater than acetyl-beta-methylcholine greater than butyryl-choline). |
1982-05-12 |
2023-08-12 |
human |
| J A Iwanowa-Smolenskaja, W P Barchatow. [Characteristics of central neurotransmitter metabolism in hereditary extrapyramidal disorders]. Neurologia i neurochirurgia polska. vol 15. issue 4. 1982-04-12. PMID:7329505. |
the secretion of dopamine (da), noradrenaline (na), adrenaline (a) and their precursor--dopa) as well as the activity of acetylcholinesterase (ache)--the enzyme disintegrating acetylcholine--were determined. |
1982-04-12 |
2023-08-12 |
Not clear |
| E B Rapson, D L Lee, S D Watt. Changes in the acetylcholinesterase activity of the nematode Nippostrongylus brasiliensis following treatment with benzimidazoles in vivo. Molecular and biochemical parasitology. vol 4. issue 1-2. 1982-03-13. PMID:7322189. |
acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) activities of nippostrongylus brasiliensis were measured following treatment of the hosts with oxfendazole and mebendazole. |
1982-03-13 |
2023-08-12 |
Not clear |