| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Kiloh, A L Harvey, W E Glove. Actions of 4-methyl-2-aminopyridine on neuromuscular transmission and contractility of skeletal muscle. European journal of pharmacology. vol 70. issue 1. 1981-06-23. PMID:6260515. |
when tested after inhibition of acetylcholinesterase activity with neostigmine the effect of 4m2ap on responses to indirect stimulation was greatly reduced and responses to acetylcholine were depressed. |
1981-06-23 |
2023-08-12 |
rat |
| K Schoene, J Steinhanses, A Wertman. Aging of soman-inhibited acetylcholinesterase: PH-rate profiles and temperature dependence in absence and in presence of effectors. Biochimica et biophysica acta. vol 616. issue 2. 1981-06-13. PMID:7213645. |
the influence of ph and temperature upon the dealkylation (aging) of soman-inhibited acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) was investigated. |
1981-06-13 |
2023-08-12 |
Not clear |
| P A Berge. Biochemistry and the schizophrenia. Old concepts and new hypothesis. The Journal of nervous and mental disease. vol 169. issue 2. 1981-05-13. PMID:7009786. |
studies with the reversible acetylcholinesterase inhibitor physostigmine and the dopamine agonist methylphenidate have led to the suggestion that acetylcholine and dopamine imbalance may be involved in schizophrenia. |
1981-05-13 |
2023-08-12 |
human |
| M Israël, B Lesbat. [Continuous detection of the release of acetylcholine from the electric organ of Torpedo using a chemiluminescence reaction]. Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles. vol 291. issue 8. 1981-04-21. PMID:6780228. |
acetylcholine is hydrolysed by acetylcholinesterase; the choline liberated is oxidized by choline oxidase to betaïne; the h2o2 generated triggers the luminescence of luminol in presence of peroxidase. |
1981-04-21 |
2023-08-12 |
Not clear |
| B V Sastry, V E Janson, A K Chaturved. Inhibition of human sperm motility by inhibitors of choline acetyltransferase. The Journal of pharmacology and experimental therapeutics. vol 216. issue 2. 1981-04-21. PMID:7463354. |
human spermatozoa contain choline acetyltransferase (cha), acetylcholinesterase and acetylcholine (ach). |
1981-04-21 |
2023-08-12 |
human |
| S T George, A S Balasubramania. The identity of the serotonin-sensitive aryl acylamidase with acetylcholinesterase from human erythrocytes, sheep basal ganglia and electric eel. European journal of biochemistry. vol 111. issue 2. 1981-04-13. PMID:7460914. |
apart from inhibition by serotonin and acetylcholine the purified aryl acylamidases from all the three sources were potently inhibited by neostygmine, eserine and bw 284c51, all strong inhibitors of acetylcholinesterase. |
1981-04-13 |
2023-08-12 |
human |
| C Burgun, J M Warter, P Veil, G Cremel, A Waksma. Influence of acetylcholine on rebinding of soluble acetylcholinesterase to a synaptosomal fraction from rat brain. Biochimie. vol 62. issue 10. 1981-03-27. PMID:7448235. |
influence of acetylcholine on rebinding of soluble acetylcholinesterase to a synaptosomal fraction from rat brain. |
1981-03-27 |
2023-08-12 |
rat |
| C Burgun, J M Warter, P Veil, G Cremel, A Waksma. Influence of acetylcholine on rebinding of soluble acetylcholinesterase to a synaptosomal fraction from rat brain. Biochimie. vol 62. issue 10. 1981-03-27. PMID:7448235. |
acetylcholinesterase (acetylcholine acetylhydrolase e.c. |
1981-03-27 |
2023-08-12 |
rat |
| C Burgun, J M Warter, P Veil, G Cremel, A Waksma. Influence of acetylcholine on rebinding of soluble acetylcholinesterase to a synaptosomal fraction from rat brain. Biochimie. vol 62. issue 10. 1981-03-27. PMID:7448235. |
solubilization of both bulk protein and acetylcholinesterase by lubrol wx and triton x 100 after acetylcholine incubation of synaptosomal fractions is much lower than in the non incubated preparation. |
1981-03-27 |
2023-08-12 |
rat |
| M P Goeldner, C G Hirt. Specific photoaffinity labeling induced by energy transfer: application to irreversible inhibition of acetylcholinesterase. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 11. 1981-03-24. PMID:6935657. |
this substance is a competitive inhibitor of acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) and is able to inactivate the enzyme either by photoaffinity labeling after irradiation at 410 nm or by an energy transfer reaction after irradiation at 295 nm. |
1981-03-24 |
2023-08-12 |
Not clear |
| C Gangitano, L Fumagalli, A Del Fà, C Olivieri-Sangiacom. [Acetylcholine receptors and acetylcholinesterase activity in cultured chick ciliary ganglia]. Bollettino della Societa italiana di biologia sperimentale. vol 56. issue 14. 1981-03-24. PMID:7448050. |
[acetylcholine receptors and acetylcholinesterase activity in cultured chick ciliary ganglia]. |
1981-03-24 |
2023-08-12 |
chicken |
| R L Rotundo, D M Fambroug. Secretion of acetylcholinesterase: relation to acetylcholine receptor metabolism. Cell. vol 22. issue 2 Pt 2. 1981-03-17. PMID:7448874. |
acetylcholinesterase (ache) and acetylcholine receptors (achr) are muscle-specific glycoproteins present (achr) are muscle-specific glycoproteins present in cultured chick embryo muscle cells. |
1981-03-17 |
2023-08-12 |
chicken |
| J J Guina. The decay of end-plate currents in neostigmine-treated frog muscle blocked by acetylcholine or tubocurarine. The Journal of physiology. vol 305. 1981-02-19. PMID:6969307. |
(with acetylcholinesterase inhibited by neostigmine) were measured with a view to inferring the extent of acetylcholine (ach) binding. |
1981-02-19 |
2023-08-12 |
Not clear |
| P R Finley, R J Williams, D A Licht. Evaluation of a new homogeneous enzyme inhibitor immunoassay of serum thyroxine with use of a bichromatic analyzer. Clinical chemistry. vol 26. issue 12. 1981-01-29. PMID:7000392. |
the assay is based on inhibition of hydrolysis of the substrate, acetyl-beta-(methylthio)choline iodide, by acetylcholinesterase (acetylcholine hydrolase; ec 3.1.1.7). |
1981-01-29 |
2023-08-12 |
Not clear |
| b' S Bon, J Massouli\\xc3\\xa. Collagen-tailed and hydrophobic components of acetylcholinesterase in Torpedo marmorata electric organ. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 8. 1981-01-26. PMID:6933497.' |
we have distinguished three fractions of acetylcholinesterase (acchoe; acetylcholine acetylhydrolase, ec 3.1.1.7) from torpedo marmorata electric organs, according to their solubilization characteristics. |
1981-01-26 |
2023-08-12 |
Not clear |
| A S Brooks, G E Tiller, W G Struv. 9-(5-Carboxypentylamino)-acridine. An affinity adsorbent ligand for Electrophorus acetylcholinesterase. Biochimica et biophysica acta. vol 615. issue 2. 1980-12-18. PMID:6893418. |
this affinity adsorbent is efficient and specific for purification acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) from electrophorus electricus electric organ. |
1980-12-18 |
2023-08-12 |
Not clear |
| T H Meede. Purification and characterization of an ascidian larval acerylcholinesterase. Biochimica et biophysica acta. vol 615. issue 2. 1980-12-18. PMID:7417454. |
larval acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) of the ascidian ciona intestinalis (l.) was purified by a two-step affinity chromatography procedure. |
1980-12-18 |
2023-08-12 |
Not clear |
| H Betz, J P Bourgeois, J P Changeu. Evolution of cholinergic proteins in developing slow and fast skeletal muscles in chick embryo. The Journal of physiology. vol 302. 1980-11-24. PMID:7411453. |
the contents in total protein and in acetylcholinesterase activity follow similar development patterns in both muscles, but, after the 15th day in ovo, the accumulation of choline acetyltransferase activity and of acetylcholine nicotinic receptor sites as determined by alpha-bungarotoxin binding occurs at a faster rate in a.l.d. |
1980-11-24 |
2023-08-12 |
chicken |
| Jayasundar, M M Vohr. Recent studies of the actions of cholinomimetic drugs on adrenergic nerves and their implications for the cholinergic link hypothesis. Canadian journal of physiology and pharmacology. vol 58. issue 1. 1980-08-25. PMID:6247039. |
thus far, evidence suggests that the only possible action of endogenous acetylcholine (ach) present near noradrenaline (na) stores is an inhibition of the release of na from the adrenergic nerve terminals and that na is released only when the action of acetylcholinesterase is inhibited. |
1980-08-25 |
2023-08-12 |
Not clear |
| R J Greenspan, J A Finn, J C Hal. Acetylcholinesterase mutants in Drosophila and their effects on the structure and function of the central nervous system. The Journal of comparative neurology. vol 189. issue 4. 1980-08-15. PMID:6769980. |
mutations that eliminate acetylcholinesterase (ache) activity were used to study the effects of disrupted acetylcholine metabolism on the form and function of the central nervous system in drosophila melanogaster. |
1980-08-15 |
2023-08-12 |
drosophila_melanogaster |