| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D H Smal. Non-cholinergic actions of acetylcholinesterases: proteases regulating cell growth and development? Trends in biochemical sciences. vol 15. issue 6. 1990-09-10. PMID:2200163. |
the enzyme acetylcholinesterase has a well-established function in limiting the duration of acetylcholine's action at cholinergic synapses. |
1990-09-10 |
2023-08-11 |
Not clear |
| A B Cachelin, D Colquhou. Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp. The Journal of physiology. vol 415. 1990-09-04. PMID:2561785. |
acetylcholine (ach) concentrations between 1 and 1000 microm were used, after inactivation of acetylcholinesterase. |
1990-09-04 |
2023-08-11 |
Not clear |
| M Adler, M G Filber. Role of butyrylcholinesterase in canine tracheal smooth muscle function. FEBS letters. vol 267. issue 1. 1990-08-16. PMID:2365076. |
the role of butyrylcholinesterase (buche) and acetylcholinesterase (ache) in in regulating acetylcholine (ach) lifetime was investigated by use of selective cholinesterase (che) inhibitors. |
1990-08-16 |
2023-08-11 |
Not clear |
| P A Pelckmans, Y M Van Maercke, M H De Maeyer, A G Herman, T J Verbeure. Cholinergic and adrenergic contractile properties of the canine ileocolonic junction. The Journal of pharmacology and experimental therapeutics. vol 254. issue 1. 1990-08-13. PMID:1973195. |
the presence of neostigmine to inhibit acetylcholinesterase did not alter the relative sensitivities of the tissues to acetylcholine. |
1990-08-13 |
2023-08-11 |
Not clear |
| Y Oyama, N Hori, C N Allen, D O Carpente. Influences of trypsin and collagenase on acetylcholine responses of physically isolated single neurons of Aplysia californica. Cellular and molecular neurobiology. vol 10. issue 2. 1990-08-13. PMID:2163751. |
edrophonium, a cholinesterase inhibitor, has previously been shown to augment the na acetylcholine response in this preparation by inhibition of acetylcholinesterase. |
1990-08-13 |
2023-08-11 |
aplysia |
| R P Maickel, D R Kinney, N D Ryker, M B Nichol. Effects of environmental temperature on hypothermia and neuroendocrine changes induced by soman. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 14. issue 4. 1990-08-06. PMID:2361572. |
plasma levels of corticosterone, glucose, and free fatty acids, as well as acetylcholinesterase activity in plasma, erythrocytes, and brain were determined over a 96-hr time course in rats maintained at 23-25, 14-16, and 3-5 degrees c. considerable inhibition of plasma and erythrocyte acetylcholine hydrolysis activity was observed after administration of soman at all three environmental temperatures. |
1990-08-06 |
2023-08-11 |
rat |
| C Magill-Solc, U J McMaha. Agrin-like molecules in motor neurons. Journal de physiologie. vol 84. issue 1. 1990-08-02. PMID:2193148. |
according to the agrin hypothesis molecules that mediate the nerve-induced aggregation of acetylcholine receptors and acetylcholinesterase on developing and regenerating skeletal muscle fibers are similar or identical to agrin, a protein extracted from the electric organ of marine rays. |
1990-08-02 |
2023-08-11 |
Not clear |
| J C Szerb, A Fin. Is glutamate a co-transmitter in cortical cholinergic terminals? Effects of nucleus basalis lesion and of presynaptic muscarinic agents. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:1972643. |
to obtain additional evidence in support of the co-transmitter role of glutamate in cortical cholinergic terminals proposed by docherty et al., the right nucleus basalis in rats was lesioned with ibotenic acid; resulting changes in cortical acetylcholinesterase (ache) staining, glutamate content, and the release of [3h]acetylcholine ([ 3h]ach) and glutamate from cortical slices from the two sides were compared. |
1990-08-01 |
2023-08-11 |
rat |
| T Arendt, Y Allen, R M Marchbanks, M M Schugens, J Sinden, P L Lantos, J A Gra. Cholinergic system and memory in the rat: effects of chronic ethanol, embryonic basal forebrain brain transplants and excitotoxic lesions of cholinergic basal forebrain projection system. Neuroscience. vol 33. issue 3. 1990-07-02. PMID:2636702. |
oral administration of ethanol (20% v/v) to male sprague-dawley rats for different periods of time up to 28 weeks resulted in profound reductions of acetylcholine content, in vitro synthesis and release of acetylcholine, choline uptake, activities of choline acetyltransferase, acetylcholinesterase and pyruvate decarboxylase, content of noradrenaline, serotonin and, to a lesser extent, dopamine throughout the brain. |
1990-07-02 |
2023-08-11 |
rat |
| R A Giniatullin, R N Khazipo. [The development of desensitization during rhythmic activity of the synapse and in the course of generating a single signal]. Biulleten' eksperimental'noi biologii i meditsiny. vol 108. issue 12. 1990-06-04. PMID:2561349. |
it was revealed, that under conditions promoting ds (hyperpolarization, muscle warming, rise of calcium concentration as well as treatment by the ds--potentiating agent--proadifen) decrease of the postsynaptic membrane sensitivity to the acetylcholine can develop after few multiquantal end-plate currents--and when acetylcholinesterase is inhibited--during the response to a single quantum of acetylcholine. |
1990-06-04 |
2023-08-11 |
Not clear |
| U J Krull, J D Brennan, R S Brown, S Hosein, B D Hougham, E T Vandenber. Chemical transduction with fluorescent lipid membranes using selective interactions of acetylcholine receptor with agonist/antagonist and acetylcholine with substrate. The Analyst. vol 115. issue 2. 1990-04-30. PMID:2321768. |
structural changes in vesicles with a 7:3 mole ratio of dipalmitoylphosphatidyl choline to dipalmitoylphosphatidic acid were observed for selective interactions between acetylcholinesterase and acetylcholine. |
1990-04-30 |
2023-08-11 |
Not clear |
| R Pant, D Raman. Therapeutic action of acetylcholine in malathion toxicity. Indian journal of biochemistry & biophysics. vol 26. issue 4. 1990-04-23. PMID:2628263. |
administration of malathion to the developing philosamia ricini larvae induces accumulation of acetylcholine, marked inhibition of acetylcholinesterase activity, depletion of all nutrients, heavy weight loss and high mortality. |
1990-04-23 |
2023-08-11 |
Not clear |
| H S Lotwick, L W Haynes, J Ha. Glycyl-L-glutamine stimulates the accumulation of A12 acetylcholinesterase but not of nicotinic acetylcholine receptors in quail embryonic myotubes by a cyclic AMP-independent mechanism. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:2156012. |
glycyl-l-glutamine stimulates the accumulation of a12 acetylcholinesterase but not of nicotinic acetylcholine receptors in quail embryonic myotubes by a cyclic amp-independent mechanism. |
1990-04-20 |
2023-08-11 |
Not clear |
| H S Lotwick, L W Haynes, J Ha. Glycyl-L-glutamine stimulates the accumulation of A12 acetylcholinesterase but not of nicotinic acetylcholine receptors in quail embryonic myotubes by a cyclic AMP-independent mechanism. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:2156012. |
myotubes prepared from the japanese quail embryo at 9 days gestation were cultivated in the presence of glycyl-l-glutamine (gly-gln, beta-endorphin c-terminal dipeptide) or glycyl-glutamic acid (gly-glu), and changes in the activity of acetylcholinesterase (ache) molecular forms and binding of 125i-alpha-bungarotoxin (alpha bgt) to cell surface nicotinic acetylcholine receptors were measured. |
1990-04-20 |
2023-08-11 |
Not clear |
| A S Cohen, A J Ole. An extract of lionfish (Pterois volitans) spine tissue contains acetylcholine and a toxin that affects neuromuscular transmission. Toxicon : official journal of the International Society on Toxinology. vol 27. issue 12. 1990-04-20. PMID:2560846. |
toxicity was retained after hydrolysis of acetylcholine by exogenous acetylcholinesterase, but heart function was no longer affected. |
1990-04-20 |
2023-08-11 |
Not clear |
| C E Olson, V Chhajlani, J T August, E D Schmel. Novel allosteric sites on human erythrocyte acetylcholinesterase identified by two monoclonal antibodies. Archives of biochemistry and biophysics. vol 277. issue 2. 1990-04-06. PMID:1689985. |
monoclonal antibodies against human erythrocyte acetylcholinesterase (acetylcholine acetylhydrolase ec 3.1.1.7) have been examined for inhibition of enzyme activity. |
1990-04-06 |
2023-08-11 |
human |
| J E Sweeney, P S Puttfarcken, J T Coyl. Galanthamine, an acetylcholinesterase inhibitor: a time course of the effects on performance and neurochemical parameters in mice. Pharmacology, biochemistry, and behavior. vol 34. issue 1. 1990-04-03. PMID:2626444. |
the time course of the effects of the long-acting acetylcholinesterase (ache) inhibitor, galanthamine, on a spatial navigation task and on ache and acetylcholine (ach) levels were investigated in mice. |
1990-04-03 |
2023-08-11 |
mouse |
| P C Gunaratna, G S Wilso. Optimization of multienzyme flow reactors for determination of acetylcholine. Analytical chemistry. vol 62. issue 4. 1990-04-02. PMID:2310017. |
acetylcholine and choline eluting from the lc column are introduced into a reactor containing immobilized acetylcholinesterase, which hydrolyzes acetylcholine to choline. |
1990-04-02 |
2023-08-11 |
Not clear |
| K Bruns, E R Casilla. Partial purification and characterization of an acetylcarnitine hydrolase from bovine epididymal spermatozoa. Archives of biochemistry and biophysics. vol 277. issue 1. 1990-03-20. PMID:2306112. |
similar studies with the acetylcholinesterase yielded a k'm for acetylcholine of about 300 microm and a v'max of 165 nmol min-1 mg protein-1. |
1990-03-20 |
2023-08-11 |
cattle |
| J C Jay, K F Baral. Denervated single myofibers: neurite interactions and synaptic molecules. Muscle & nerve. vol 12. issue 12. 1990-03-20. PMID:2622472. |
(1) three molecules that are found at the neuromuscular junction (nmj)--acetylcholinesterase (ache), acetylcholine receptors (achrs), and gelasmin (an acetylcholine receptor clustering factor that is found enriched at nmj of adult muscle)--were reduced with increasing periods of denervation but not with aging. |
1990-03-20 |
2023-08-11 |
rat |