| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L G Cost. Interactions of neurotoxicants with neurotransmitter systems. Toxicology. vol 49. issue 2-3. 1988-06-28. PMID:2897731. |
organophosphorus insecticides owe their acute toxicity to inhibition of acetylcholinesterase and accumulation of acetylcholine at cholinergic receptors. |
1988-06-28 |
2023-08-11 |
Not clear |
| M Yamad. [Changes in the innervation of the uterus during pregnancy and following parturition. Histochemical and electron microscopic observations in rat and humans]. Nihon Sanka Fujinka Gakkai zasshi. vol 40. issue 2. 1988-06-03. PMID:3361169. |
the activity of acetylcholinesterase (ache) in rat uterine cholinergic nerves clearly decreased during pregnancy. |
1988-06-03 |
2023-08-11 |
rat |
| L J Reed, J de Belleroch. Increased polyphosphoinositide responsiveness in the cerebral cortex induced by cholinergic denervation. Journal of neurochemistry. vol 50. issue 5. 1988-06-02. PMID:3361311. |
parameters of cholinergic function, namely, acetylcholinesterase activity, muscarinic acetylcholine receptor number, and the depolarisation-induced release of acetylcholine, fall in ipsilateral cortex subsequent to lesion. |
1988-06-02 |
2023-08-11 |
rat |
| G Kounenis, M Koutsoviti-Papadopoulou, V Elezoglo. The excitatory effect of the new histamine H2-receptor antagonist nizatidine (LY 139037) on the guinea pig ileum. Journal of pharmacobio-dynamics. vol 10. issue 11. 1988-05-24. PMID:2895808. |
these findings suggest that nizatidine exerts an excitatory effect on the guinea pig ileum which seems to be associated with the cholinergic system, probably through a direct and/or an indirect mechanism (inhibition of acetylcholinesterase and/or increased release of acetylcholine). |
1988-05-24 |
2023-08-11 |
Not clear |
| F Dagani, F Marzatico, D Curt. Oxidative metabolism of nonsynaptic mitochondria isolated from rat brain hippocampus: a comparative regional study. Journal of neurochemistry. vol 50. issue 4. 1988-04-21. PMID:2831301. |
cholinergic markers--choline acetyltransferase, acetylcholinesterase activities, and high-affinity choline uptake--evaluated on synaptosomes showed the classic regional pattern with an enrichment in the striatum (striatum much greater than hippocampus). |
1988-04-21 |
2023-08-11 |
rat |
| G M Gilad, J M Rabey, Y Tizabi, V H Gila. Age-dependent loss and compensatory changes of septohippocampal cholinergic neurons in two rat strains differing in longevity and response to stress. Brain research. vol 436. issue 2. 1988-03-25. PMID:3435831. |
acetylcholinesterase histochemical staining served to localize cholinergic neurons and their terminals in the septum and hippocampus respectively. |
1988-03-25 |
2023-08-11 |
rat |
| G S Zubenko, J Moossy, I Hanin, A J Martinez, G R Rao, U Kop. Bilateral symmetry of cholinergic deficits in Alzheimer's disease. Archives of neurology. vol 45. issue 3. 1988-03-17. PMID:3341949. |
the specific activities of the cholinergic enzymes, choline acetyltransferase and acetylcholinesterase, as well as the density of muscarinic binding sites, were determined in five corresponding left and right regions of 16 brains obtained at autopsy from patients with histologically confirmed alzheimer's disease. |
1988-03-17 |
2023-08-11 |
Not clear |
| M C Altavista, S Gozzo, C Iacopino, A Albanes. A genetic study of neostriatal cholinergic neurones in C57BL/6 and DBA/2 mice. Functional neurology. vol 2. issue 3. 1988-02-20. PMID:3692272. |
in the present study butcher's pharmaco-histochemical technique for acetylcholinesterase has been employed for a morphometrical analysis of striatal cholinergic neurones in crossbred c57bl/6 x dba/2 f1 mice. |
1988-02-20 |
2023-08-11 |
mouse |
| E Bartha, J Szelényi, K Szilágyi, V Venter, N T Thu Ha, P Páldi-Haris, S Hollá. Altered lymphocyte acetylcholinesterase activity in patients with senile dementia. Neuroscience letters. vol 79. issue 1-2. 1987-12-09. PMID:3499586. |
reductions in the acetylcholinesterase (ache) activity of certain brain areas in patients with senile dementia of alzheimer type (sdat) have been found to correlate with the severity of the disease, suggesting a central cholinergic lesion. |
1987-12-09 |
2023-08-11 |
human |
| P J Riekkinen, H Soininen, J Sirviö, K Reinikainen, E L Helkala, L Paljärv. Dementia without cholinergic deficit. Gerontology. vol 33. issue 3-4. 1987-11-20. PMID:3653707. |
we examined the role of cholinergic system in multi-infarct dementia (mid) by measuring acetylcholinesterase (ache) activities in cerebrospinal fluid (csf) of clinically diagnosed mid patients, alzheimer's disease (ad) patients and controls. |
1987-11-20 |
2023-08-11 |
Not clear |
| R J Boegman, Y Smith, A Paren. Quinolinic acid does not spare striatal neuropeptide Y-immunoreactive neurons. Brain research. vol 415. issue 1. 1987-10-15. PMID:2957024. |
the striatal cholinergic neurons identified by means of the di-isopropylfluorophosphate (dfp)-pharmacohistochemical procedure for acetylcholinesterase were found to be more resistant than npy-immunoreactive cells to the action of the neurotoxin. |
1987-10-15 |
2023-08-11 |
rat |
| E P Fiedler, M J Marks, A C Collin. Postnatal development of cholinergic enzymes and receptors in mouse brain. Journal of neurochemistry. vol 49. issue 3. 1987-09-23. PMID:3612135. |
the developmental profiles for the cholinergic enzymes acetylcholinesterase and choline acetyltransferase, and the muscarinic and nicotinic receptors were determined in whole mouse brain. |
1987-09-23 |
2023-08-11 |
mouse |
| G M Cohe. Acetylcholinesterase activity in the embryonic chick's inner ear. Hearing research. vol 28. issue 1. 1987-09-11. PMID:3497144. |
putative cholinergic efferent endings, as demonstrated by the presence of a localized acetylcholinesterase reaction product and visualized by phase-contrast microscopy, appeared in the lagenar macula and cristae ampullares on the 11th embryonic day (ed) and in the basilar papilla by the 13th ed. |
1987-09-11 |
2023-08-11 |
chicken |
| M Alexandrova, M Holzbauer, K Racke, D F Sharma. Acetylcholinesterase in the rat neurohypophysis is decreased after dehydration and released by stimulation of the pituitary stalk. Neuroscience. vol 21. issue 2. 1987-09-01. PMID:3614640. |
the observed loss of enzyme activity during dehydration may be the consequence of a prolonged activation of cholinergic nerves in the gland, leading to an increased release of acetylcholinesterase, which is not immediately replaced by fresh enzyme. |
1987-09-01 |
2023-08-11 |
rat |
| R S Aronstam, M D Smith, J J Buccafusc. Clonidine prevents the short-term down regulation of muscarinic receptors in mouse brain induced by the acetylcholinesterase inhibitor soman. Neuroscience letters. vol 78. issue 1. 1987-09-01. PMID:3614769. |
it is possible that a reversible inhibition of acetylcholinesterase by clonidine protects the enzyme from irreversible inactivation by soman, thereby decreasing the extent of chronic cholinergic overstimulation with its attendant down regulation of muscarinic receptors. |
1987-09-01 |
2023-08-11 |
mouse |
| H J Martínez, C F Dreyfus, G M Jonakait, I B Blac. Nerve growth factor selectively increases cholinergic markers but not neuropeptides in rat basal forebrain in culture. Brain research. vol 412. issue 2. 1987-08-28. PMID:3607470. |
exposure to ngf also increased the activity of another cholinergic marker, the catabolic enzyme, acetylcholinesterase. |
1987-08-28 |
2023-08-11 |
rat |
| S Herscovich, D Gersho. Effects of aging and physical training on the neuromuscular junction of the mouse. Gerontology. vol 33. issue 1. 1987-08-12. PMID:3596265. |
synaptic function was found to be considerably reduced in old age, as revealed by the activity of the cholinergic enzymes choline acetyltransferase (cat) and acetylcholinesterase (ache). |
1987-08-12 |
2023-08-11 |
mouse |
| E B Ezerman, L F Krome. Transplants of cholinergic septal explants reinnervate adult rodent hippocampus. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:3580909. |
analysis of fiber ingrowth by acetylcholinesterase (ache) histochemistry at various timepoints post-transplantation shows little difference in the developmental time course or extent of cholinergic axon ingrowth into the host hippocampus between the suspension transplants and the explant transplants. |
1987-07-16 |
2023-08-11 |
rat |
| J E Springer, M W Tayrien, R Lo. Regional analysis of age-related changes in the cholinergic system of the hippocampal formation and basal forebrain of the rat. Brain research. vol 407. issue 1. 1987-07-14. PMID:3580852. |
in an attempt to clarify conflicting reports of age-related changes in cholinergic systems of the rat hippocampal formation and basal forebrain, we compared aged (40 months) and adult (12 months) male rats using quantitative, regional receptor autoradiography in addition to radiolabelled assays of choline acetyltransferase (chat) and acetylcholinesterase (ache). |
1987-07-14 |
2023-08-11 |
rat |
| J J Hagan, J A Tonnaer, H Rijk, C L Broekkamp, A M van Delf. Facilitation of amphetamine-induced rotation by muscarinic antagonists is correlated with M2 receptor affinity. Brain research. vol 410. issue 1. 1987-07-14. PMID:3580900. |
in these rats, ipsiversive rotation induced by amphetamine sulphate (1 mg/kg, s.c.) was dose-dependently inhibited by the cholinergic agonists oxotremorine, rs86 and pilocarpine and by the acetylcholinesterase inhibitor physostigmine. |
1987-07-14 |
2023-08-11 |
rat |