| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Biegon, V Greenberger, M Sega. Quantitative histochemistry of brain acetylcholinesterase and learning rate in the aged rat. Neurobiology of aging. vol 7. issue 3. 1986-08-11. PMID:3724956. |
using a newly developed method for quantitative acetylcholinesterase (ache) histochemistry we find a substantial decrease in ache content in aged rats compared to young controls in the cholinergic cell body regions (the ventral pallidum and the medial septal nuclei) and, to a smaller extent in the projection areas (the cortex and hippocampus). |
1986-08-11 |
2023-08-11 |
rat |
| Y Egozi, M Sokolovsky, E Schejter, I Blatt, H Zakut, A Matzkel, H Sore. Divergent regulation of muscarinic binding sites and acetylcholinesterase in discrete regions of the developing human fetal brain. Cellular and molecular neurobiology. vol 6. issue 1. 1986-08-07. PMID:3719620. |
our findings suggest divergent regulation for cholinergic binding sites and cholinesterase in the fetal human brain and imply that the expression of muscarinic receptors is related to the development of cholinergic transmission, while acetylcholinesterase is also involved in other functions in the fetal human brain. |
1986-08-07 |
2023-08-11 |
human |
| M Yamad. [Observations on the morphology of the pelvic ganglion of the female rat]. Nihon Sanka Fujinka Gakkai zasshi. vol 38. issue 5. 1986-07-28. PMID:3722952. |
in the majority of ganglion cells, on the surface of cell bodies and processes upon which numerous cholinergic nerve endings are located, the histochemical reaction for acetylcholinesterase (ache) was of varied intensity. |
1986-07-28 |
2023-08-11 |
rat |
| M R Meyer, G R Reddy, J S Edward. Metabolic changes in deafferented central neurons of an insect, Acheta domesticus. II. Effects on cholinergic binding sites and acetylcholinesterase. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 6. 1986-07-18. PMID:3712003. |
effects on cholinergic binding sites and acetylcholinesterase. |
1986-07-18 |
2023-08-11 |
cricket |
| F J Huff, J C Maire, J H Growdon, S Corkin, R J Wurtma. Cholinesterases in cerebrospinal fluid. Correlations with clinical measures in Alzheimer's disease. Journal of the neurological sciences. vol 72. issue 2-3. 1986-07-08. PMID:3711929. |
acetylcholinesterase and butyrylcholinesterase activities in cerebrospinal fluid were measured in 17 patients with alzheimer's disease and 6 control patients, as potential clinical measures of impaired cholinergic neurotransmission in alzheimer's disease. |
1986-07-08 |
2023-08-11 |
Not clear |
| E J Mufson, T L Martin, D C Mash, B H Wainer, M M Mesula. Cholinergic projections from the parabigeminal nucleus (Ch8) to the superior colliculus in the mouse: a combined analysis of horseradish peroxidase transport and choline acetyltransferase immunohistochemistry. Brain research. vol 370. issue 1. 1986-06-27. PMID:3708316. |
choline acetyltransferase (chat) immunocytochemistry, acetylcholinesterase histochemistry and muscarinic receptor autoradiography demonstrated a cholinergic innervation within the superior colliculus. |
1986-06-27 |
2023-08-11 |
mouse |
| C Ferrand, M C Giess, B Raynaud, J P Swerts, C Delteil, D Clarous, M Webe. The role of extracellular signals in the differentiation of cholinergic neurons from the CNS and PNS in culture. Journal de physiologie. vol 80. issue 4. 1986-06-10. PMID:2871180. |
this "cholinergic factor" impaired the development of three norepinephrine synthesizing enzymes and of acetylcholinesterase (ache) in these cultures. |
1986-06-10 |
2023-08-11 |
rat |
| E A Grove, V B Domesick, W J Naut. Light microscopic evidence of striatal input to intrapallidal neurons of cholinergic cell group Ch4 in the rat: a study employing the anterograde tracer Phaseolus vulgaris leucoagglutinin (PHA-L). Brain research. vol 367. issue 1-2. 1986-06-09. PMID:3697714. |
within the globus pallidus, pha-l-filled striatofugal axons were seen to approach cholinergic neurons, identified with either acetylcholinesterase histochemistry or choline acetyltransferase immunohistochemistry, and, apparently, to contact the surface of such cells with axonal varicosities. |
1986-06-09 |
2023-08-11 |
rat |
| A Lysakowski, B H Wainer, D B Rye, G Bruce, L B Hers. Cholinergic innervation displays strikingly different laminar preferences in several cortical areas. Neuroscience letters. vol 64. issue 1. 1986-05-07. PMID:3008035. |
in addition, the pattern of staining observed with acetylcholinesterase histochemistry, which has been used for many years to demonstrate putative cholinergic fibers, only partially matches the staining pattern obtained with the more specific cholinergic marker, chat. |
1986-05-07 |
2023-08-11 |
rat |
| M L Mortense. Management of acute childhood poisonings caused by selected insecticides and herbicides. Pediatric clinics of North America. vol 33. issue 2. 1986-04-29. PMID:3515303. |
these compounds inhibit acetylcholinesterase, resulting in cholinergic signs that are reversible with atropine administration. |
1986-04-29 |
2023-08-11 |
human |
| E Brandan, N C Inestros. The synaptic form of acetylcholinesterase binds to cell-surface heparan sulfate proteoglycans. Journal of neuroscience research. vol 15. issue 2. 1986-04-25. PMID:2937928. |
we have previously communicated that heparan sulfate and heparin released 16s acetylcholinesterase (ache) from cholinergic synapses. |
1986-04-25 |
2023-08-11 |
Not clear |
| R C Gupta, G T Patterson, W D Dettbar. Mechanisms involved in the development of tolerance to DFP toxicity. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 5. issue 6 Pt 2. 1986-04-08. PMID:4092885. |
rats treated daily with diisopropylfluorophosphate (dfp) (0.5 mg/kg, sc), an inhibitor of acetylcholinesterase (ache) activity, exhibited the symptoms of cholinergic hyperactivity between days 3 and 5 similar to those observed 15 min after a single acute dosage (1.5 mg/kg, sc). |
1986-04-08 |
2023-08-11 |
rat |
| J Weston, S A Greenfiel. Application of acetylcholinesterase to the substantia nigra induces stereotypy in rats. Behavioural brain research. vol 18. issue 1. 1986-04-03. PMID:3911982. |
the functional significance of acetylcholinesterase in the substantiae nigrae of freely moving animals is discussed in the light of its apparent association with dopaminergic rather than cholinergic systems. |
1986-04-03 |
2023-08-11 |
rat |
| C F Höhmann, F F Ebne. Development of cholinergic markers in mouse forebrain. I. Choline acetyltransferase enzyme activity and acetylcholinesterase histochemistry. Brain research. vol 355. issue 2. 1986-03-11. PMID:4084778. |
measurements of choline acetyltransferase (chat) activity were made during the development of the neocortical cholinergic innervation, and correlated with the development of the acetylcholinesterase (ache) staining pattern in mouse cerebral cortex and several other areas of the forebrain between the time of initial onset and maturity chat activity can first be measured on postnatal day 6 (p6). |
1986-03-11 |
2023-08-11 |
mouse |
| J N Crawley, J A Olschowka, D I Diz, D M Jacobowit. Behavioral investigation of the coexistence of substance P, corticotropin releasing factor, and acetylcholinesterase in lateral dorsal tegmental neurons projecting to the medial frontal cortex of the rat. Peptides. vol 6. issue 5. 1986-02-19. PMID:2417203. |
one possible functional significance of the coexistence of sp, crf, and acetylcholinesterase, in neurons projecting to the medial frontal cortex in rats, appears to be a modulatory potentiation of cholinergic response by sp, and a modulatory inhibition of the cholinergic response by crf. |
1986-02-19 |
2023-08-11 |
rat |
| D J Stewart, D F MacFabe, L W Leun. Topographical projection of cholinergic neurons in the basal forebrain to the cingulate cortex in the rat. Brain research. vol 358. issue 1-2. 1986-02-18. PMID:4075131. |
the cholinergic innervation of the rat's posterior cingulate cortex (brodmann's area 29) was studied using acetylcholinesterase (ache) histochemistry. |
1986-02-18 |
2023-08-11 |
rat |
| P Kása, I Hani. Ethylcholine mustard aziridinium blocks the axoplasmic transport of acetylcholinesterase in cholinergic nerve fibres of the rat. Histochemistry. vol 83. issue 4. 1986-01-16. PMID:2415497. |
ethylcholine mustard aziridinium blocks the axoplasmic transport of acetylcholinesterase in cholinergic nerve fibres of the rat. |
1986-01-16 |
2023-08-11 |
rat |
| J W Geddes, D T Monaghan, C W Cotman, I T Lott, R C Kim, H C Chu. Plasticity of hippocampal circuitry in Alzheimer's disease. Science (New York, N.Y.). vol 230. issue 4730. 1985-12-27. PMID:4071042. |
an enhancement of acetylcholinesterase activity in the dentate gyrus molecular layer, indicative of septal afferent sprouting, was also observed in those patients with a minimal loss of cholinergic neurons. |
1985-12-27 |
2023-08-11 |
human |
| J C Torres, N C Inestros. Interaction of heparin with multimolecular aggregates of acetylcholinesterase. Cellular and molecular neurobiology. vol 5. issue 3. 1985-12-23. PMID:4064078. |
it has been reported previously that heparin, a sulfated glycosaminoglycan, releases the asymmetric 16 s form of acetylcholinesterase (ache) from cholinergic synapses. |
1985-12-23 |
2023-08-11 |
Not clear |
| J F Rodriguez-Sierra, B J Morle. Evidence that cell bodies in the arcuate nucleus of the hypothalamus are not cholinergic. Neuroendocrinology. vol 41. issue 5. 1985-12-18. PMID:4058675. |
based on studies using acetylcholinesterase (ache) histochemistry, it has been proposed that the cholinergic neurons controlling hormone release originate in neurons of the arcuate nucleus (ah). |
1985-12-18 |
2023-08-11 |
cat |