| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E J Mufson, D C Mash, L B Hers. Neurofibrillary tangles in cholinergic pedunculopontine neurons in Alzheimer's disease. Annals of neurology. vol 24. issue 5. 1989-01-24. PMID:3202615. |
the cholinergic neurons located within the pedunculopontine nucleus (ch5) of patients with alzheimer's disease (ad; n = 15), parkinson's disease (pd; n = 2), and neurologically normal (n = 6) subjects were visualized immunohistochemically using choline acetyltransferase, pharmacohistochemically using acetylcholinesterase, or by reduced histochemical methods using nicotinamide adenine dinucleotide phosphate diaphorase (nadph-d). |
1989-01-24 |
2023-08-11 |
human |
| S J Kish, A Olivier, F Dubeau, Y Robitaille, A L Sherwi. Increased activity of choline acetyltransferase and acetylcholinesterase in actively epileptic human cerebral cortex. Epilepsy research. vol 2. issue 4. 1989-01-17. PMID:3197693. |
we measured the activities of the cholinergic marker synthetic and catabolic enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) in surgical specimens obtained from 38 patients immediately following anterior temporal lobectomy for intractable epilepsy. |
1989-01-17 |
2023-08-11 |
human |
| C Nyakas, P G Luiten, B Balkan, D G Spence. Changes in septo-hippocampal projections after lateral entorhinal or combined entorhinal-raphé lesions as studied by anterograde tracing methods. Brain research bulletin. vol 21. issue 2. 1988-12-27. PMID:3191413. |
comparison with concurrent acetylcholinesterase (ache) staining and immunocytochemical demonstration of choline acetyltransferase (chat) confirm the cholinergic nature of this plasticity response. |
1988-12-27 |
2023-08-11 |
Not clear |
| P Aas, P Walday, R Tansø, F Fonnu. The effect of acetylcholinesterase-inhibition on the tonus of guinea-pig bronchial smooth muscle. Biochemical pharmacology. vol 37. issue 21. 1988-12-15. PMID:3190758. |
the ed50 of the cholinergic agonist carbachol was not changed even when the acetylcholinesterase (ache) activity was inhibited completely. |
1988-12-15 |
2023-08-11 |
Not clear |
| V Magrí, J J Buccafusco, R S Aronsta. Protection by clonidine from the cardiovascular changes and lethality following soman administration in the rat: role of brain acetylcholine. Toxicology and applied pharmacology. vol 95. issue 3. 1988-12-05. PMID:3188010. |
these results are consistent with the ability of clonidine to offer protection against centrally acting acetylcholinesterase inhibitors as a result of marked inhibition of cholinergic function in certain brain regions. |
1988-12-05 |
2023-08-11 |
rat |
| S de la Porte, P Courbin, M Grouselle, D Duflo, J P Desmazes, D Georgescauld, J Koeni. [Is muscular acetylcholinesterase activity correlated with the intracellular concentration of free calcium?]. Reproduction, nutrition, developpement. vol 28. issue 3B. 1988-11-25. PMID:3141991. |
recently it was suggested that ion fluxes through membranes regulate the level of two cholinergic macromolecules, the acetylcholine receptor and the a12 form of acetylcholinesterase (ache), the presumed synaptic form of the enzyme. |
1988-11-25 |
2023-08-11 |
rat |
| R J Ross, S Tsagarakis, A Grossman, L Nhagafoong, R J Touzel, L H Rees, G M Besse. GH feedback occurs through modulation of hypothalamic somatostatin under cholinergic control: studies with pyridostigmine and GHRH. Clinical endocrinology. vol 27. issue 6. 1988-10-27. PMID:2901302. |
we have studied the effect of increased cholinergic tone on the gh response to growth hormone-releasing hormone (ghrh) and on gh feedback, using pyridostigmine, an acetylcholinesterase inhibitor. |
1988-10-27 |
2023-08-11 |
human |
| R Quirio. Characterization and autoradiographic distribution of hemicholinium-3 high-affinity choline uptake sites in mammalian brain. Synapse (New York, N.Y.). vol 1. issue 4. 1988-10-20. PMID:3138770. |
this hypothesis is also supported by quantitative autoradiographic data which demonstrate that the discrete distribution of [3h]hc-3 binding sites correlates very well with the known distribution of other cholinergic markers such as choline acetyltransferase (chat), acetylcholinesterase (ache), hacu, and [3h]ah-5183 (blocker of the vesicular transport of acetylcholine). |
1988-10-20 |
2023-08-11 |
rat |
| R M Ridley, N A Samson, H F Baker, J A Johnso. Visuospatial learning impairment following lesion of the cholinergic projection to the hippocampus. Brain research. vol 456. issue 1. 1988-10-13. PMID:3136860. |
ibotenic acid lesions of the vertical limb of the diagonal band of broca (vdb) in marmosets produced significant depletions in choline acetyltransferase (chat) activity and a decrease in acetylcholinesterase (ache) staining in the hippocampal formation and entorhinal cortex (to which the cholinergic neurones of the vdb project) but not in the neocortex or amygdala. |
1988-10-13 |
2023-08-11 |
Not clear |
| C Schwab, G Brückner, V Mares, D Biesol. A combined method of acetylcholinesterase histochemistry and [3H]thymidine autoradiography: application to neurogenesis of the rat basal forebrain cholinergic system. Neuroscience letters. vol 90. issue 1-2. 1988-10-13. PMID:3412649. |
a combined method of acetylcholinesterase histochemistry and [3h]thymidine autoradiography: application to neurogenesis of the rat basal forebrain cholinergic system. |
1988-10-13 |
2023-08-11 |
rat |
| R J Boegman, A Paren. The response of striatal neuropeptide Y and cholinergic neurons to excitatory amino acid agonists. Brain research. vol 452. issue 1-2. 1988-09-15. PMID:2900050. |
the effect of excitatory amino acid antagonists on antagonist on neuropeptide y (npy) and cholinergic neurons in the striatum of the rat was studied by means of npy immunocytochemistry, dfp histochemistry for acetylcholinesterase (ache), and biochemical determinations of choline acetyltransferase (chat). |
1988-09-15 |
2023-08-11 |
rat |
| B Bossy, M Ballivet, P Spiere. Conservation of neural nicotinic acetylcholine receptors from Drosophila to vertebrate central nervous systems. The EMBO journal. vol 7. issue 3. 1988-09-08. PMID:2840281. |
as we found previously for a gene whose product is also involved in cholinergic synapses, acetylcholinesterase, the leader encodes short open reading frames, which might be involved in translation control. |
1988-09-08 |
2023-08-11 |
drosophila_melanogaster |
| S P Mahadik, H Laev, A Korenovsky, S E Karpia. Haloperidol alters rat CNS cholinergic system: enzymatic and morphological analyses. Biological psychiatry. vol 24. issue 2. 1988-08-23. PMID:3291956. |
chemical and morphological changes in cholinergic marker enzymes, acetylcholinesterase (ache), and choline acetyltransferase (chat) of striatum, hippocampus, and cerebral cortex were studied following haloperidol treatment of rats. |
1988-08-23 |
2023-08-11 |
rat |
| M E Appleyard, J L Vercher, S A Greenfiel. Release of acetylcholinesterase from the guinea-pig cerebellum in vivo. Neuroscience. vol 25. issue 1. 1988-08-18. PMID:3393274. |
in the cerebellum there is scant evidence for cholinergic transmission but a large amount of acetylcholinesterase. |
1988-08-18 |
2023-08-11 |
Not clear |
| M E Appleyard, J L Vercher, S A Greenfiel. Release of acetylcholinesterase from the guinea-pig cerebellum in vivo. Neuroscience. vol 25. issue 1. 1988-08-18. PMID:3393274. |
it is concluded that acetylcholinesterase is released from cerebellar neurons in association with physiological events, yet unrelated to cholinergic transmission. |
1988-08-18 |
2023-08-11 |
Not clear |
| R Bissoli, A Contestabil. Evolution of neurotransmitter-related markers in the vertebrate telencephalon. Comparative microchemical study in discrete brain regions of a frog and a turtle. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 89. issue 2. 1988-08-12. PMID:2899002. |
cholinergic markers choline acetyltransferase (chat) and acetylcholinesterase (ache) were rather uniformly distributed in the frog telencephalon, while, in the turtle, cholinergic markers were several-fold higher in the basal telencephalon, particularly in the striatum, than in the pallium. |
1988-08-12 |
2023-08-11 |
Not clear |
| E Orona, B E Hunter, D W Walke. Ethanol exposure following unilateral entorhinal deafferentation alters synaptic reorganization in the rat dentate gyrus: a quantitative analysis of acetylcholinesterase histochemistry. Experimental neurology. vol 101. issue 1. 1988-08-12. PMID:3391254. |
synaptic reorganization of the commissural/associational (c/a) and cholinergic (primarily septal) afferents was evaluated in the dentate gyrus processed for acetylcholinesterase (ache) histochemistry. |
1988-08-12 |
2023-08-11 |
rat |
| R B Fishman, S M Breedlov. Neonatal androgen maintains sexually dimorphic muscles in the absence of innervation. Muscle & nerve. vol 11. issue 6. 1988-08-08. PMID:3386664. |
bc/la muscles were present in all tp-treated spinalectomized females, and staining of these muscles with alpha-bungarotoxin or for acetylcholinesterase showed no evidence of cholinergic innervation. |
1988-08-08 |
2023-08-11 |
rat |
| W H Griffit. Membrane properties of cell types within guinea pig basal forebrain nuclei in vitro. Journal of neurophysiology. vol 59. issue 5. 1988-07-29. PMID:3385475. |
double-labeling techniques have shown that sahp cells stain positively for acetylcholinesterase (ache) and are presumably cholinergic (22). |
1988-07-29 |
2023-08-11 |
Not clear |
| P Aa. The toxic effect of an AChE-inhibitor on the cholinergic nervous system in airway smooth muscle. Toxicology. vol 49. issue 1. 1988-06-30. PMID:3376127. |
excessive cholinergic stimulation of presynaptic muscarinic cholinergic receptors, due to complete inhibition of acetylcholinesterase (ache) by o-(1,2,2-trimethylpropyl)-methyl-phosphonofluoridate (soman), reduced the release of acetylcholine (ach) from cholinergic nerves in rat bronchi by almost 25%. |
1988-06-30 |
2023-08-11 |
rat |