| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clarissa Waites, Xiaoyi Qu, Francesca Bartolin. The synaptic life of microtubules. Current opinion in neurobiology. vol 69. 2021-09-13. PMID:33873059. |
here, we review emerging literature demonstrating that microtubules enter synapses and control central aspects of synaptic activity, including neurotransmitter release and synaptic plasticity. |
2021-09-13 |
2023-08-13 |
Not clear |
| Sheng-Tao Ho. The regulatory and enzymatic functions of CRMPs in neuritogenesis, synaptic plasticity, and gene transcription. Neurochemistry international. vol 139. 2021-08-11. PMID:32652266. |
through post-translational modifications, such as phosphorylation, o-glcnacylation, sumoylation, and proteolytic cleavage, crmps participate in synaptic plasticity by modulating nmda receptors, l- and n-type voltage-gated calcium channels (vgccs), thus affecting neurotransmitter release. |
2021-08-11 |
2023-08-13 |
Not clear |
| Lan Wang, Peter Walte. Msp1/ATAD1 in Protein Quality Control and Regulation of Synaptic Activities. Annual review of cell and developmental biology. vol 36. 2021-08-10. PMID:32886535. |
in addition, atad1 is implicated in the regulation of synaptic plasticity, mediating the release of neurotransmitter receptors from postsynaptic scaffolds to allow their trafficking. |
2021-08-10 |
2023-08-13 |
Not clear |
| Hongxiu Zhang, Xiansu Chi, Wenchao Pan, Shijun Wang, Zhe Zhang, Haijun Zhao, Yuan Wang, Zhichun Wu, Miaomiao Zhou, Shan Ma, Qitao Zhao, Ke M. Antidepressant mechanism of classical herbal formula lily bulb and Rehmannia decoction: insights from gene expression profile of medial prefrontal cortex of mice with stress-induced depression-like behavior. Genes, brain, and behavior. vol 19. issue 5. 2021-07-15. PMID:32129566. |
lbrd treatment altered the enriched degs in the signaling pathways of γ-aminobutyric acid (gaba) and glutamate neurotransmitter, synaptic plasticity and axon guidance, circadian rhythm and neural-immunity. |
2021-07-15 |
2023-08-13 |
mouse |
| Dorien Vandael, Keimpe Wierda, Katlijn Vints, Pieter Baatsen, Lies De Groef, Lieve Moons, Vasily Rybakin, Natalia V Gounk. Corticotropin-releasing factor induces functional and structural synaptic remodelling in acute stress. Translational psychiatry. vol 11. issue 1. 2021-07-14. PMID:34234103. |
functionally, crf leads to a rapid increase in synaptic strength of sc input into ca1 neurons, e.g., increase in spontaneous neurotransmitter release, paired-pulse facilitation, and repetitive excitability and improves synaptic plasticity: long-term potentiation (ltp) and long-term depression (ltd). |
2021-07-14 |
2023-08-13 |
mouse |
| Helena Caria Martins, Gerhard Schrat. MicroRNA-dependent control of neuroplasticity in affective disorders. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33941769. |
in rodents, mirnas regulate synaptic plasticity by controlling the morphology of dendrites and spines and the expression of neurotransmitter receptors. |
2021-06-28 |
2023-08-13 |
Not clear |
| Stephen D Worrell, Thomas J Goul. Therapeutic potential of ketamine for alcohol use disorder. Neuroscience and biobehavioral reviews. vol 126. 2021-06-28. PMID:33989669. |
while alcohol use disorder (aud) pathology is complex and involves multiple neurotransmitter systems, changes in synaptic plasticity, hippocampal neurogenesis, and neural connectivity have been implicated in the behavioral characteristics of aud. |
2021-06-28 |
2023-08-13 |
Not clear |
| Yifeng Cheng, Xueyi Xie, Jiayi Lu, Himanshu Gangal, Wei Wang, Sebastian Melo, Xuehua Wang, Jared Jerger, Kayla Woodson, Eric Garr, Yufei Huang, Patricia Janak, Jun Wan. Optogenetic induction of orbitostriatal long-term potentiation in the dorsomedial striatum elicits a persistent reduction of alcohol-seeking behavior in rats. Neuropharmacology. vol 191. 2021-06-23. PMID:33894220. |
striatal synaptic plasticity is modulated by several critical neurotransmitter receptors, including dopamine d1 receptors (d1rs) and adenosine a2a receptors (a2ars). |
2021-06-23 |
2023-08-13 |
rat |
| Marcus Augusto-Oliveira, Gabriela P Arrifano, Priscila Y Takeda, Amanda Lopes-Araújo, Leticia Santos-Sacramento, Daniel C Anthony, Alexei Verkhratsky, Maria Elena Crespo-Lope. Astroglia-specific contributions to the regulation of synapses, cognition and behaviour. Neuroscience and biobehavioral reviews. vol 118. 2021-06-21. PMID:32768488. |
thus, astrocytes regulate the synaptic connectivity of the neuronal networks by supporting neurotransmitter metabolism, synaptogenesis, synaptic elimination and the synaptic plasticity that contributes to cognitive processing including learning, memory, emotionality and behaviour. |
2021-06-21 |
2023-08-13 |
Not clear |
| Jae-Man Song, Minji Kang, Da-Ha Park, Sunha Park, Sanghyeon Lee, Young Ho Su. Pathogenic The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 11. 2021-06-11. PMID:33500274. |
pathogenic metabotropic glutamate receptor 7 (mglu7) is an inhibitory heterotrimeric g-protein-coupled receptor that modulates neurotransmitter release and synaptic plasticity at presynaptic terminals in the mammalian central nervous system. |
2021-06-11 |
2023-08-13 |
Not clear |
| Jens Häggman Henrikson, Ana Rita Pombo Antunes, Tadeusz Wieloch, Karsten Rusche. Enhanced functional recovery by levodopa is associated with decreased levels of synaptogyrin following stroke in aged mice. Brain research bulletin. vol 155. 2021-06-03. PMID:31805305. |
this study investigates if dopamine might affect plasticity by having a direct effect on synaptic plasticity through alterations in neurotransmitter release and re-uptake. |
2021-06-03 |
2023-08-13 |
mouse |
| Neeraj K Tiwari, Monica Sathyanesan, Vikas Kumar, Samuel S Newto. A Comparative Analysis of Erythropoietin and Carbamoylated Erythropoietin Proteome Profiles. Life (Basel, Switzerland). vol 11. issue 4. 2021-05-18. PMID:33921564. |
bioinformatics enrichment analysis of the protein expression profiles revealed the upregulation of protein functions related to memory formation such as synaptic plasticity, long term potentiation (ltp), neurotransmitter transport, synaptic vesicle priming, and dendritic spine development. |
2021-05-18 |
2023-08-13 |
rat |
| Zhe-Qi Xu, Wen-Jun Zhang, Ding-Feng Su, Guo-Qing Zhang, Chao-Yu Mia. Cellular responses and functions of α7 nicotinic acetylcholine receptor activation in the brain: a narrative review. Annals of translational medicine. vol 9. issue 6. 2021-04-16. PMID:33850906. |
the activation of α7nachr results in a series of physiological processes which have both short-term and long-term effects on cells, for example, calcium influx, neurotransmitter release, synaptic plasticity, and excitatory transmission. |
2021-04-16 |
2023-08-13 |
Not clear |
| Yingying Zhao, Shuanglin Wang, Xiaopeng Song, Junliang Yuan, Dong Qi, Xiaohuan Gu, Michael Yaoyao Yin, Zhou Han, Yanbing Zhu, Zhandong Liu, Yongbo Zhang, Ling Wei, Zheng Zachory We. Glial Cell-Based Vascular Mechanisms and Transplantation Therapies in Brain Vessel and Neurodegenerative Diseases. Frontiers in cellular neuroscience. vol 15. 2021-04-13. PMID:33841101. |
it has been noted that glial cells including astrocytes (which outnumber other cell types in the cns) essentially contribute more to the bbb integrity, extracellular homeostasis, neurotransmitter release, regulation of neurogenic niches in response to neuroinflammatory stimulus, and synaptic plasticity. |
2021-04-13 |
2023-08-13 |
Not clear |
| Francesca Fagiani, Cristina Lanni, Marco Racchi, Stefano Govon. (Dys)regulation of Synaptic Activity and Neurotransmitter Release by β-Amyloid: A Look Beyond Alzheimer's Disease Pathogenesis. Frontiers in molecular neuroscience. vol 14. 2021-03-16. PMID:33716668. |
beside its widely studied role in the pathogenesis of alzheimer's disease (ad), β-amyloid (aβ) is a normal and soluble product of neuronal metabolism that regulates several key physiological functions, exerting neuromodulatory effects on synaptic plasticity, memory, and neurotransmitter release. |
2021-03-16 |
2023-08-13 |
Not clear |
| Ricardo Martín, Nuria García-Font, Alberto Samuel Suárez-Pinilla, David Bartolomé-Martín, José Javier Ferrero, Rafael Luján, Magdalena Torres, José Sánchez-Priet. β-Adrenergic Receptors/Epac Signaling Increases the Size of the Readily Releasable Pool of Synaptic Vesicles Required for Parallel Fiber LTP. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 45. 2021-02-01. PMID:33046543. |
the second messenger camp is an important determinant of synaptic plasticity that is associated with enhanced neurotransmitter release. |
2021-02-01 |
2023-08-13 |
Not clear |
| Silvia Giovedì, Margherita Maria Ravanelli, Barbara Parisi, Barbara Bettegazzi, Fabrizia Claudia Guarnier. Dysfunctional Autophagy and Endolysosomal System in Neurodegenerative Diseases: Relevance and Therapeutic Options. Frontiers in cellular neuroscience. vol 14. 2021-01-05. PMID:33390907. |
beside this, emerging evidence has pointed to their involvement in the regulation of the synaptic proteome needed to guarantee an efficient neurotransmitter release and synaptic plasticity. |
2021-01-05 |
2023-08-13 |
Not clear |
| Tomasz Jaworsk. Control of neuronal excitability by GSK-3beta: Epilepsy and beyond. Biochimica et biophysica acta. Molecular cell research. vol 1867. issue 9. 2020-12-07. PMID:32450268. |
although the complete repertoire of gsk-3β neuronal substrates has not been defined, emerging evidence shows that different ion channels and their accessory proteins controlling excitability, neurotransmitter release, and synaptic transmission are regulated by gsk-3β, thereby supporting mechanisms of synaptic plasticity in cognition. |
2020-12-07 |
2023-08-13 |
mouse |
| Shan Shi, Ke Ma, Na-Ryum Bin, Hidekiyo Harada, Xiaoyu Xie, Mengjia Huang, Haiyu Liu, Soomin Lee, Xue Fan Wang, Roberto Adachi, Philippe P Monnier, Liang Zhang, Shuzo Sugit. Syntaxin-3 is dispensable for basal neurotransmission and synaptic plasticity in postsynaptic hippocampal CA1 neurons. Scientific reports. vol 10. issue 1. 2020-11-25. PMID:31959797. |
recent evidence suggests that snare fusion machinery play critical roles in postsynaptic neurotransmitter receptor trafficking, which is essential for synaptic plasticity. |
2020-11-25 |
2023-08-13 |
mouse |
| Anne C Wolfes, Camin Dea. The diversity of synaptotagmin isoforms. Current opinion in neurobiology. vol 63. 2020-11-09. PMID:32663762. |
recent work has highlighted how brain function relies on additional isoforms, with roles in postsynaptic receptor endocytosis, vesicle trafficking, membrane repair, synaptic plasticity, and protection against neurodegeneration, for example, in addition to the traditional concept of synaptotagmin-mediated neurotransmitter release - in neurons as well as glia, and at different timepoints. |
2020-11-09 |
2023-08-13 |
mouse |