Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Laia Alegre-Zurano, Alba García-Baos, Adriana Castro-Zavala, Mireia Medrano, Ines Gallego-Landin, Olga Valverd. The FAAH inhibitor URB597 reduces cocaine intake during conditioned punishment and mitigates cocaine seeking during withdrawal. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-07-27. PMID:37499453. |
the endocannabinoid system is prominently implicated in the control of cocaine reinforcement due to its relevant role in synaptic plasticity and neurotransmitter modulation in the mesocorticolimbic system. |
2023-07-27 |
2023-08-14 |
mouse |
Mayuri N Tuwar, Wei-Hung Chen, Arthur M Chiwaya, Hsu-Ling Yeh, Minh H Nguyen, Chyi-Huey Ba. Brain-Derived Neurotrophic Factor (BDNF) and Translocator Protein (TSPO) as Diagnostic Biomarkers for Acute Ischemic Stroke. Diagnostics (Basel, Switzerland). vol 13. issue 13. 2023-07-14. PMID:37443691. |
brain-derived neurotrophic factor (bdnf) interacts with tropomyosin-related kinase b (trkb) to promote neuronal growth, survival, differentiation, neurotransmitter release, and synaptic plasticity. |
2023-07-14 |
2023-08-14 |
Not clear |
T Chase Francis, Alessandra Porc. Emotionally clocked out: cell-type specific regulation of mood and anxiety by the circadian clock system in the brain. Frontiers in molecular neuroscience. vol 16. 2023-07-13. PMID:37441675. |
in the brain, circadian clocks regulate neuronal physiological functions, including neuronal activity, synaptic plasticity, protein expression, and neurotransmitter release which in turn affect mood-related behaviors via cell-type specific mechanisms. |
2023-07-13 |
2023-08-14 |
human |
Ameneh Rezayof, Zahra Ghasemzadeh, Oveis Hosseinzadeh Sahaf. Addictive drugs modify neurogenesis, synaptogenesis and synaptic plasticity to impair memory formation through neurotransmitter imbalances and signaling dysfunction. Neurochemistry international. 2023-07-09. PMID:37423274. |
addictive drugs modify neurogenesis, synaptogenesis and synaptic plasticity to impair memory formation through neurotransmitter imbalances and signaling dysfunction. |
2023-07-09 |
2023-08-14 |
Not clear |
Svilen Georgiev, Silvio Rizzol. The long-loop recycling (LLR) of synaptic components as a question of economics. Molecular and cellular neurosciences. 2023-05-26. PMID:37236414. |
the recycling steps have been amply described in functional terms, with, for example, synaptic vesicle recycling being essential for neurotransmitter release, and postsynaptic receptor recycling being a fundamental feature of synaptic plasticity. |
2023-05-26 |
2023-08-14 |
Not clear |
Hyung Jun Kim, Seong Yong Kim, Ga Eun Kim, Han Jun Ji. Association between genetic polymorphisms of synaptophysin (SYP) gene and attention deficit hyperactivity disorder in Korean subjects. Genes & genomics. 2023-05-03. PMID:37133725. |
synaptophysin (syp) regulates neurotransmitter release and synaptic plasticity. |
2023-05-03 |
2023-08-14 |
human |
Teresa Soda, Valentina Brunetti, Roberto Berra-Romani, Francesco Mocci. The Emerging Role of N-Methyl-D-Aspartate (NMDA) Receptors in the Cardiovascular System: Physiological Implications, Pathological Consequences, and Therapeutic Perspectives. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835323. |
n-methyl-d-aspartate receptors (nmdars) are ligand-gated ion channels that are activated by the neurotransmitter glutamate, mediate the slow component of excitatory neurotransmission in the central nervous system (cns), and induce long-term changes in synaptic plasticity. |
2023-02-25 |
2023-08-14 |
Not clear |
Sang Hun Lee, Vadim Y Bolshakov, Jie She. Presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus. Molecular brain. vol 16. issue 1. 2023-01-30. PMID:36710361. |
previous studies of ps function in the hippocampus demonstrated that loss of ps results in the impairment of short- and long-term synaptic plasticity and neurotransmitter release at hippocampal schaffer collateral (sc) and mossy fiber (mf) synapses. |
2023-01-30 |
2023-08-14 |
mouse |
Ursula Veronika Leuschner, Stephanie Kleinle, Andreas Holzinger, Jochen Nee. Novel SYN1 variant in two brothers with focal epilepsy and their prompt response to valproate. Neuropediatrics. 2023-01-24. PMID:36693418. |
synapsins are neuron-specific phosphoproteins that modulate neurotransmitter release, synaptic plasticity, and molecular processes shaping higher brain functions. |
2023-01-24 |
2023-08-14 |
Not clear |
Elisa Corti, Carlos B Duart. The role of post-translational modifications in synaptic AMPA receptor activity. Biochemical Society transactions. 2023-01-11. PMID:36629507. |
ampa-type receptors for the neurotransmitter glutamate are very dynamic entities, and changes in their synaptic abundance underlie different forms of synaptic plasticity, including long-term synaptic potentiation (ltp), long-term depression (ltd) and homeostatic scaling. |
2023-01-11 |
2023-08-14 |
Not clear |
Chuan Tang, Ye Jin, Huan Wan. The biological alterations of synapse/synapse formation in sepsis-associated encephalopathy. Frontiers in synaptic neuroscience. vol 14. 2022-12-19. PMID:36530954. |
therefore, we summarized sae-induced synaptic dysfunction, such as synaptic plasticity inhibition, neurotransmitter imbalance, and synapses loss. |
2022-12-19 |
2023-08-14 |
Not clear |
Yifeng Rang, Huan Liu, Chunhong Li. The mechanisms of learning and memory impairment caused by nonylphenol: a narrative review based on in vivo and in vitro studies. Environmental science and pollution research international. 2022-11-26. PMID:36434456. |
based on the studies involved in behavior tests, these mechanisms were classified as oxidative stress, neurotransmitter disorder, synaptic plasticity impairment, and neuron injury. |
2022-11-26 |
2023-08-14 |
human |
Subramanian Boopathi, Ramón Garduño-Juáre. Calcium inhibits penetration of Alzheimer's Aβ Proteins. vol 90. issue 12. 2022-11-02. PMID:36321654. |
calcium inhibits penetration of alzheimer's aβ calcium ion regulation plays a crucial role in maintaining neuronal functions such as neurotransmitter release and synaptic plasticity. |
2022-11-02 |
2023-08-14 |
Not clear |
Lie Zhou, Jia-Yao Xiong, Yu-Qian Chai, Lu Huang, Zi-Yang Tang, Xin-Feng Zhang, Bo Liu, Jun-Tao Zhan. Possible antidepressant mechanisms of omega-3 polyunsaturated fatty acids acting on the central nervous system. Frontiers in psychiatry. vol 13. 2022-09-19. PMID:36117650. |
these include that of (1) anti-neuroinflammatory; (2) hypothalamus-pituitary-adrenal (hpa) axis; (3) anti-oxidative stress; (4) anti-neurodegeneration; (5) neuroplasticity and synaptic plasticity; and (6) modulation of neurotransmitter systems. |
2022-09-19 |
2023-08-14 |
Not clear |
Y Laurisa Arenales Arauz, Gargi Ahuja, Ype P T Kamsma, Arjan Kortholt, Eddy A van der Zee, Marieke J G van Heuvele. Potential of Whole-Body Vibration in Parkinson's Disease: A Systematic Review and Meta-Analysis of Human and Animal Studies. Biology. vol 11. issue 8. 2022-08-26. PMID:36009865. |
the studies on the neuropathological mechanisms (18 studies) show wbv effects on neuroinflammation (hedges' g = -1.12) and several specific wbv effects on neurotransmitter systems, growth factors, neurogenesis, synaptic plasticity and oxidative stress. |
2022-08-26 |
2023-08-14 |
mouse |
Benjamin R Rost, Jonas Wietek, Ofer Yizhar, Dietmar Schmit. Optogenetics at the presynapse. Nature neuroscience. 2022-07-14. PMID:35835882. |
presynaptically localized opsins combined with light stimulation at the terminals allow light-mediated neurotransmitter release, presynaptic inhibition, induction of synaptic plasticity and specific manipulation of individual components of the presynaptic machinery. |
2022-07-14 |
2023-08-14 |
Not clear |
MaKayla F Cox, Erin R Hascup, Andrzej Bartke, Kevin N Hascu. Friend or Foe? Defining the Role of Glutamate in Aging and Alzheimer's Disease. Frontiers in aging. vol 3. 2022-07-13. PMID:35821835. |
considering the importance of glutamate signaling in synaptic plasticity, motor movement, and cognition, this neurotransmitter serves as a juncture between cognitive health and disease. |
2022-07-13 |
2023-08-14 |
mouse |
Hardy Hagena, Mirko Feldmann, Denise Manahan-Vaugha. Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness. Scientific reports. vol 12. issue 1. 2022-06-01. PMID:35650390. |
lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness. |
2022-06-01 |
2023-08-13 |
mouse |
Hardy Hagena, Mirko Feldmann, Denise Manahan-Vaugha. Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness. Scientific reports. vol 12. issue 1. 2022-06-01. PMID:35650390. |
here, we explored whether recovery from adaptive changes in the expression of plasticity-related neurotransmitter receptors and hippocampal synaptic plasticity occurs in the time-period of up to 12 months after onset of sensory loss. |
2022-06-01 |
2023-08-13 |
mouse |
Haider Sarwar, Shafiya Imtiaz Rafiqi, Showkat Ahmad, Sruthi Jinna, Sawleha Arshi Khan, Tamanna Karim, Omar Qureshi, Zeeshan A Zahid, Jon D Elhai, Jason C Levine, Shazia J Naqvi, Juan C Jaume, Shahnawaz Ima. Hyperinsulinemia Associated Depression. Clinical medicine insights. Endocrinology and diabetes. vol 15. 2022-05-02. PMID:35494421. |
increased inflammatory cytokines have also been shown to disrupt neurotransmitter metabolism and synaptic plasticity which play a role in the development of depression via inhibiting serotonin, dopamine, melatonin, and glutamate signaling. |
2022-05-02 |
2023-08-13 |
Not clear |