| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiang Gu, Ling Li. Spatiotemporal expression of AP-2/myosin Ⅵ in mouse cochlear IHCs and correlation with auditory function. Acta oto-laryngologica. 2024-04-25. PMID:38662892. |
recycling of synaptic vesicles plays an important role in vesicle pool replenishment, neurotransmitter release and synaptic plasticity. |
2024-04-25 |
2024-04-28 |
mouse |
| J Wren Kim, Adeline J H Yong, Erin E Aisenberg, Joseph H Lobel, Wei Wang, Ted M Dawson, Valina L Dawson, Ruixuan Gao, Yuh Nung Jan, Helen S Bateup, Nicholas T Ingoli. Molecular recording of calcium signals via calcium-dependent proximity labeling. Nature chemical biology. 2024-04-24. PMID:38658655. |
in neurons, calcium transients play a central role in regulating neurotransmitter release and synaptic plasticity. |
2024-04-24 |
2024-04-28 |
Not clear |
| Maria P Mogavero, Michele Salemi, Giuseppe Lanza, Antonio Rinaldi, Giovanna Marchese, Maria Ravo, Maria Grazia Salluzzo, Amedeo Antoci, Lourdes M DelRosso, Oliviero Bruni, Luigi Ferini-Strambi, Raffaele Ferr. Unveiling the pathophysiology of restless legs syndrome through transcriptome analysis. iScience. vol 27. issue 4. 2024-04-15. PMID:38617564. |
genetic predisposition plays a key role in rls and evidence indicates its inflammatory nature; the high involvement of mainly neurotropic viruses and the torch complex might trigger inflammatory/immune reactions in genetically predisposed subjects and activate a series of biological pathways-especially il-17, receptor potential channels, nuclear factor kappa-light-chain-enhancer of activated b cells, nod-like receptor, mitogen-activated protein kinase, p53, mitophagy, and ferroptosis-involved in neurotransmitter mechanisms, synaptic plasticity, axon guidance, neurodegeneration, carcinogenesis, and metabolism. |
2024-04-15 |
2024-04-17 |
human |
| Shubhrajit Roy, Svetlana Lutsenk. Mechanism of Cu entry into the brain: many unanswered questions. Neural regeneration research. vol 19. issue 11. 2024-03-25. PMID:38526278. |
brain tissue requires high amounts of copper (cu) for its key physiological processes, such as energy production, neurotransmitter synthesis, maturation of neuropeptides, myelination, synaptic plasticity, and radical scavenging. |
2024-03-25 |
2024-03-27 |
Not clear |
| Hayder M Al-Kuraishy, Esraa H Fahad, Salah Al-Windy, Suzy A El-Sherbeni, Walaa A Negm, Gaber El-Saber Batih. The effects of cholesterol and statins on Parkinson's neuropathology: a narrative review. Inflammopharmacology. 2024-03-19. PMID:38499742. |
different studies highlighted that statins, via inhibition of brain hmg-coa, can affect neuronal integrity through suppression of neuronal cholesterol, which regulates synaptic plasticity and neurotransmitter release. |
2024-03-19 |
2024-03-21 |
Not clear |
| Raj A Katariya, Shivkumar S Sammeta, Mayur B Kale, Nandkishor R Kotagale, Milind J Umekar, Brijesh G Taksand. Agmatine as a Novel Intervention for Alzheimer's Disease: Pathological Insights and Cognitive Benefits. Ageing research reviews. 2024-03-13. PMID:38479477. |
it also exerts neuroprotective effects, modulates neurotransmitter systems, enhances synaptic plasticity, and stimulates neurogenesis. |
2024-03-13 |
2024-03-16 |
Not clear |
| Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. |
neuroplastin, and its related molecules which are known to play a role in synaptic plasticity, neurotransmitter activities that provide balance of excitability and, different neurological diseases, have not been studied before in epilepsy. |
2024-03-04 |
2024-03-06 |
rat |
| Yousong Zhu, Qinlong Hui, Zheng Zhang, Hao Fu, Yali Qin, Qiong Zhao, Qinqing Li, Junlong Zhang, Lei Guo, Wenbin He, Cheng Ha. Advancements in the study of synaptic plasticity and mitochondrial autophagy relationship. Journal of neuroscience research. vol 102. issue 2. 2024-02-24. PMID:38400573. |
consequently, the quantity, distribution, transport, and function of mitochondria impact the stability of brain energy metabolism, thereby participating in the regulation of fundamental processes in synaptic plasticity, including neuronal differentiation, neurite outgrowth, synapse formation, and neurotransmitter release. |
2024-02-24 |
2024-02-26 |
Not clear |
| Daniela M Magalhães, Nicolas A Stewart, Myrthe Mampay, Sara O Rolle, Chloe M Hall, Emad Moeendarbary, Melanie S Flint, Ana M Sebastião, Cláudia A Valente, Marcus K Dymond, Graham K Sherida. The sphingosine 1-phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus. Journal of neurochemistry. 2024-02-10. PMID:38339785. |
moreover, direct modulation of s1p receptor-mediated lipid signalling by fty720 can impact homeostatic cns physiology, including neurotransmitter release probability, the biophysical properties of synaptic membranes, ion channel and transmembrane receptor kinetics, and synaptic plasticity mechanisms. |
2024-02-10 |
2024-02-12 |
mouse |
| Liang He, Xiyuan Duan, Shikuo Li, Ruqiang Zhang, Xulei Dai, Meilin L. Unveiling the role of astrocytes in postoperative cognitive dysfunction. Ageing research reviews. 2024-02-07. PMID:38325753. |
herein, in this context, we mainly explore the multifaceted roles of astrocytes in the context of pocd, highlighting their involvement in neuroinflammation, neurotransmitter regulation, synaptic plasticity and neurotrophic support, and discuss how pocd may augment the onset of ad. |
2024-02-07 |
2024-02-10 |
Not clear |
| Valérie Clavet-Fournier, ChungKu Lee, Waja Wegner, Nils Brose, JeongSeop Rhee, Katrin I Willi. Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation. iScience. vol 27. issue 1. 2024-01-12. PMID:38213627. |
synaptic plasticity involves changes in synaptic morphology and the number of neurotransmitter receptors, and is thought to underlie learning and memory. |
2024-01-12 |
2024-01-14 |
Not clear |
| Mariana G Fronza, Bruna F Ferreira, Isabela Pavan-Silva, Francisco S Guimarães, Sabrina F Lisbo. "NO" Time in Fear Response: Possible Implication of Nitric-Oxide-Related Mechanisms in PTSD. Molecules (Basel, Switzerland). vol 29. issue 1. 2024-01-11. PMID:38202672. |
stress predominantly affects glutamate, a neurotransmitter crucial for synaptic plasticity and memory formation. |
2024-01-11 |
2024-01-13 |
Not clear |
| Ubaid Ansari, Vincent Chen, Romteen Sedighi, Burhaan Syed, Zohaer Muttalib, Khadija Ansari, Fatima Ansari, Denise Nadora, Daniel Razick, Forshing Lu. Role of the UNC13 family in human diseases: A literature review. AIMS neuroscience. vol 10. issue 4. 2024-01-08. PMID:38188011. |
the involvement of unc13a in neurotransmitter release and synaptic plasticity is linked to als and ftd, with genetic variations affecting disease progression. |
2024-01-08 |
2024-01-10 |
human |
| Ruyu Wang, Yiwei Chen, Zhiying Wang, Baorui Cao, Jinxin Du, Tingting Deng, Meina Yang, Jinxiang Ha. Antidepressant effect of licorice total flavonoids and liquiritin: A review. Heliyon. vol 9. issue 11. 2023-12-11. PMID:38074876. |
studies have shown that lf and liquiritin can exert their antidepressant effects by improving depressive behavior, regulating endocrine and hypothalamic-pituitary-adrenal (hpa) axis function, affecting the brain-derived neurotrophic factor (bdnf)/tyrosine kinase b (trkb) signaling pathway, enhancing synaptic plasticity, increasing monoamine neurotransmitter levels, protecting nerve cells, reducing inflammation, preventing apoptosis, reducing oxidation and other ways. |
2023-12-11 |
2023-12-17 |
Not clear |
| Jongkyun Kang, Chen Zhang, Yuhao Wang, Jian Feng, Bonnie Berger, Norbert Perrimon, Jie She. Lipophorin Receptors Genetically Modulate Neurodegeneration Caused by Reduction of Psn Expression in the Aging Drosophila Brain. Genetics. 2023-11-23. PMID:37996068. |
mouse genetic analysis highlighted the importance of presenilin (ps) in learning and memory, synaptic plasticity and neurotransmitter release, and neuronal survival, and drosophila studies further demonstrated an evolutionarily conserved role of ps in neuronal survival during aging. |
2023-11-23 |
2023-11-29 |
mouse |
| Rou-Gang Xie, Guang-Yin Xu, Sheng-Xi Wu, Ceng Lu. Presynaptic glutamate receptors in nociception. Pharmacology & therapeutics. 2023-10-02. PMID:37783347. |
they modulate presynaptic neurotransmitter release and synaptic plasticity, which in turn regulates pain sensitization. |
2023-10-02 |
2023-10-07 |
Not clear |
| Anton Shkundin, Angelos Halari. Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder. Journal of personalized medicine. vol 13. issue 9. 2023-09-28. PMID:37763162. |
brain-derived neurotrophic factor (bdnf) is crucial for various aspects of neuronal development and function, including synaptic plasticity, neurotransmitter release, and supporting neuronal differentiation, growth, and survival. |
2023-09-28 |
2023-10-07 |
Not clear |
| Poppy L A Schoenberg, Alexander K Song, Emily M Mohr, Baxter P Rogers, Todd E Peterson, Barbara A Murph. Increased microglia activation in late non-central nervous system cancer survivors links to chronic systemic symptomatology. Human brain mapping. 2023-09-26. PMID:37751068. |
prolonged inflammatory expression within the central nervous system (cns) is recognized by the brain as a molecular signal of "sickness", that has knock-on effects to the blood-brain barrier, brain-spinal barrier, blood-cerebrospinal fluid barrier, neuro-axonal structures, neurotransmitter activity, synaptic plasticity, neuroendocrine function, and resultant systemic symptomatology. |
2023-09-26 |
2023-10-07 |
Not clear |
| Amin A Hafi. The neuroprotective effect of vitamin D in Parkinson's disease: association or causation. Nutritional neuroscience. 2023-09-21. PMID:37731327. |
the vd-mediated cognitive augmenting effect is interrelated to the safeguarding of synaptic plasticity and modulation of neurotransmitter release. |
2023-09-21 |
2023-10-07 |
Not clear |
| Yaoyao Ren, Shengtao Q. Constituent isoflavones of Puerariae radix as a potential neuroprotector in cognitive impairment: Evidence from preclinical studies. Ageing research reviews. 2023-08-24. PMID:37619620. |
these isoflavones prevent aβ aggregation, inhibit tau hyperphosphorylation, increase cholinergic neurotransmitter levels, reduce neuroinflammation and oxidative stress, improve synaptic plasticity, promote nerve regeneration, and prevent apoptosis. |
2023-08-24 |
2023-09-07 |
Not clear |