| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cecilia L Speyer, Jennifer S Smith, Malathi Banda, John A DeVries, Tassia Mekani, David H Gorsk. Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer. Breast cancer research and treatment. vol 132. issue 2. 2012-06-22. PMID:21681448. |
metabotropic glutamate receptors are g-protein-coupled receptors normally expressed in the central nervous system where they mediate neuronal excitability, synaptic plasticity, and feedback inhibition of neurotransmitter release. |
2012-06-22 |
2023-08-12 |
mouse |
| Francisco J Monje, Ruth Birner-Gruenberger, Barbara Darnhofer, Isabella Divisch, Daniela D Pollak, Gert Lube. Proteomics reveals selective regulation of proteins in response to memory-related serotonin stimulation in Aplysia californica ganglia. Proteomics. vol 12. issue 3. 2012-06-20. PMID:22162403. |
taken together, protein-level changes induced by the learning-related neurotransmitter serotonin in aplysia ganglia are described and a role for the abovementioned proteins in synaptic plasticity is proposed. |
2012-06-20 |
2023-08-12 |
aplysia |
| Randy D Blakely, Robert H Edward. Vesicular and plasma membrane transporters for neurotransmitters. Cold Spring Harbor perspectives in biology. vol 4. issue 2. 2012-06-12. PMID:22199021. |
the results indicate that far from the passive target of psychoactive drugs, neurotransmitter transporters undergo regulation that contributes to synaptic plasticity. |
2012-06-12 |
2023-08-12 |
Not clear |
| Renato Frischknecht, Eckart D Gundelfinge. The brain's extracellular matrix and its role in synaptic plasticity. Advances in experimental medicine and biology. vol 970. 2012-06-12. PMID:22351055. |
these include (a) the discovery that the ecm can act as a passive diffusion barrier for cell surface molecules including neurotransmitter receptors and in this way compartmentalize cell surfaces, (b) the specific functions of ecm components in actively regulating synaptic plasticity and homeostasis, and (c) the shaping processes of the ecm by extracellular proteases and in turn the activation particular signaling pathways. |
2012-06-12 |
2023-08-12 |
Not clear |
| Lu-Yun Lian, Sravan R Pandalaneni, Pryank Patel, Hannah V McCue, Lee P Haynes, Robert D Burgoyn. Characterisation of the interaction of the C-terminus of the dopamine D2 receptor with neuronal calcium sensor-1. PloS one. vol 6. issue 11. 2012-05-03. PMID:22114693. |
ncs-1 is a member of the neuronal calcium sensor (ncs) family of ef-hand ca(2+) binding proteins which has been implicated in several physiological functions including regulation of neurotransmitter release, membrane traffic, voltage gated ca(2+) channels, neuronal development, synaptic plasticity, and learning. |
2012-05-03 |
2023-08-12 |
Not clear |
| Francis E Lotrich, Hani El-Gabalawy, Lyn C Guenther, Carl F War. The role of inflammation in the pathophysiology of depression: different treatments and their effects. The Journal of rheumatology. Supplement. vol 88. 2012-03-15. PMID:22045979. |
many depressed individuals have higher levels of proinflammatory mediators, which appear to interact with many of the pathophysiological domains of depression, including neuroendocrine function, neurotransmitter metabolism, and synaptic plasticity. |
2012-03-15 |
2023-08-12 |
Not clear |
| J Suárez, O Ortíz, N Puente, F J Bermúdez-Silva, E Blanco, P Fernández-Llebrez, P Grandes, F Rodríguez de Fonseca, R Moratall. Distribution of diacylglycerol lipase alpha, an endocannabinoid synthesizing enzyme, in the rat forebrain. Neuroscience. vol 192. 2012-01-18. PMID:21756982. |
this widespread neuronal distribution of daglα is consistent with multiple roles for endocannabinoids in synaptic plasticity, including presynaptic inhibition of neurotransmitter release. |
2012-01-18 |
2023-08-12 |
mouse |
| Christian M Cremer, Joachim H R Lübke, Nicola Palomero-Gallagher, Karl Zille. Laminar distribution of neurotransmitter receptors in different reeler mouse brain regions. Brain structure & function. vol 216. issue 3. 2011-12-12. PMID:21442415. |
in the adult, reelin may regulate synaptic plasticity by modulating neurotransmitter receptor function. |
2011-12-12 |
2023-08-12 |
mouse |
| Daniel Martins-de-Souza, Laura W Harris, Paul C Guest, Sabine Bah. The role of energy metabolism dysfunction and oxidative stress in schizophrenia revealed by proteomics. Antioxidants & redox signaling. vol 15. issue 7. 2011-12-01. PMID:20673161. |
converging lines of evidence suggest that mitochondrial function may be compromised in this disorder, and this can lead to perturbations in calcium buffering, oxidative phosphorylation, increased production of reactive oxygen species, and apoptotic factors, which can, in turn, affect neuronal processes such as neurotransmitter synthesis and synaptic plasticity. |
2011-12-01 |
2023-08-12 |
Not clear |
| Akito Nakao, Yoshinori Takada, Yasuo Mor. [Calcium channels regulate neuronal function, gene expression, and development]. Brain and nerve = Shinkei kenkyu no shinpo. vol 63. issue 7. 2011-08-25. PMID:21747135. |
vddc-mediated ca2+ signaling is essential for neurotransmitter release, synaptic plasticity, and gene transcription. |
2011-08-25 |
2023-08-12 |
Not clear |
| Lucile Capuron, Andrew H Mille. Immune system to brain signaling: neuropsychopharmacological implications. Pharmacology & therapeutics. vol 130. issue 2. 2011-07-22. PMID:21334376. |
in the context of inflammation, pro-inflammatory cytokines can access the central nervous system and interact with a cytokine network in the brain to influence virtually every aspect of brain function relevant to behavior including neurotransmitter metabolism, neuroendocrine function, synaptic plasticity, and neurocircuits that regulate mood, motor activity, motivation, anxiety and alarm. |
2011-07-22 |
2023-08-12 |
Not clear |
| Ivar Reinvang, Ian J Deary, Anders M Fjell, Vidar M Steen, Thomas Espeseth, Raja Parasurama. Neurogenetic effects on cognition in aging brains: a window of opportunity for intervention? Frontiers in aging neuroscience. vol 2. 2011-07-14. PMID:21103005. |
such multiple-phenotype approaches indicate that individual variation in genes central to maintaining synaptic integrity, neurotransmitter function, and synaptic plasticity are important in affecting age-related changes in brain structure and cognition. |
2011-07-14 |
2023-08-12 |
Not clear |
| Annika Weyhersmüller, Stefan Hallermann, Nicole Wagner, Jens Eiler. Rapid active zone remodeling during synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 16. 2011-06-30. PMID:21508229. |
how can synapses change the amount of neurotransmitter released during synaptic plasticity? |
2011-06-30 |
2023-08-12 |
drosophila_melanogaster |
| Omar A Ramírez, Andrés Couv. The endoplasmic reticulum and protein trafficking in dendrites and axons. Trends in cell biology. vol 21. issue 4. 2011-05-27. PMID:21215635. |
here we review our current understanding of the er in dendrites and axons, its contribution to local trafficking of neurotransmitter receptors, and the implications for synaptic plasticity and pathology. |
2011-05-27 |
2023-08-12 |
Not clear |
| Aldamaria Puliti, Pia Irene Anna Rossi, Gianluca Caridi, Alessandro Corbelli, Masami Ikehata, Silvia Armelloni, Min Li, Cristina Zennaro, Valerio Conti, Carlotta Maria Vaccari, Michela Cassanello, Maria Grazia Calevo, Laura Emionite, Roberto Ravazzolo, Maria Pia Rastald. Albuminuria and glomerular damage in mice lacking the metabotropic glutamate receptor 1. The American journal of pathology. vol 178. issue 3. 2011-05-25. PMID:21356376. |
the metabotropic glutamate (mglu) receptor 1 (grm1) has been shown to play an important role in neuronal cells by triggering, through calcium release from intracellular stores, various signaling pathways that finally modulate neuron excitability, synaptic plasticity, and mechanisms of feedback regulation of neurotransmitter release. |
2011-05-25 |
2023-08-12 |
mouse |
| John Park, Z David Lu. Calcium channel functions in pain processing. Channels (Austin, Tex.). vol 4. issue 6. 2011-05-23. PMID:21150297. |
voltage-gated calcium channels (vgcc) play obligatory physiological roles, including modulation of neuronal: functions, synaptic plasticity, neurotransmitter release and gene transcription. |
2011-05-23 |
2023-08-12 |
Not clear |
| Matthew J Kennedy, Michael D Ehler. Mechanisms and function of dendritic exocytosis. Neuron. vol 69. issue 5. 2011-05-11. PMID:21382547. |
dendritic exocytosis is required for a broad array of neuronal functions including retrograde signaling, neurotransmitter release, synaptic plasticity, and establishment of neuronal morphology. |
2011-05-11 |
2023-08-12 |
Not clear |
| Minoru Nakayama, Chihiro Ham. Modulation of neurotransmitter receptors and synaptic differentiation by proteins containing complement-related domains. Neuroscience research. vol 69. issue 2. 2011-04-15. PMID:21093502. |
neurotransmitter receptors play central roles in basic neurotransmission and synaptic plasticity. |
2011-04-15 |
2023-08-12 |
Not clear |
| Giacinto Bagetta, Luigi Antonio Morrone, Laura Rombolà, Diana Amantea, Rossella Russo, Laura Berliocchi, Shinobu Sakurada, Tsukasa Sakurada, Domenicantonio Rotiroti, Maria Tiziana Corasanit. Neuropharmacology of the essential oil of bergamot. Fitoterapia. vol 81. issue 6. 2010-11-29. PMID:20093169. |
the behavioural and eeg spectrum power effects of beo correlate well with its exocytotic and carrier-mediated release of discrete amino acids endowed with neurotransmitter function in the mammalian hippocampus supporting the deduction that beo is able to interfere with normal and pathological synaptic plasticity. |
2010-11-29 |
2023-08-12 |
Not clear |
| Nancy M Lorenzon, Kurt G Bea. Disease causing mutations of calcium channels. Channels (Austin, Tex.). vol 2. issue 3. 2010-10-12. PMID:18836296. |
intracellular calcium ions are essential second messengers and play a role in many functions including, action potential generation, neurotransmitter and hormone release, muscle contraction, neurite outgrowth, synaptogenesis, calcium-dependent gene expression, synaptic plasticity and cell death. |
2010-10-12 |
2023-08-12 |
Not clear |