| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R F Kanzafarova, A V Kazantseva, E K Khusnutdinov. [Genetic and environmental aspects of mathematical disabilities]. Genetika. vol 51. issue 3. 2015-06-12. PMID:26027366. |
according to the first approach, learning and memory formation are influenced by variants in neurotransmitter system genes, genes involved in the working memory and synaptic plasticity. |
2015-06-12 |
2023-08-13 |
Not clear |
| L Huang, L B Zhao, Z Y Yu, X J He, L P Ma, N Li, L J Guo, W Y Fen. Long-term inhibition of Rho-kinase restores the LTP impaired in chronic forebrain ischemia rats by regulating GABAA and GABAB receptors. Neuroscience. vol 277. 2015-06-08. PMID:25050822. |
complementary interactions between the excitatory neurotransmitter glutamate and the inhibitory neurotransmitter gaba form the molecular basis of synaptic plasticity and cognitive performance. |
2015-06-08 |
2023-08-13 |
rat |
| Vorapin Chinchalongporn, Peter Koppensteiner, Deborah Prè, Wipawan Thangnipon, Leonilda Bilo, Ottavio Aranci. Connectivity and circuitry in a dish versus in a brain. Alzheimer's research & therapy. vol 7. issue 1. 2015-06-05. PMID:26045718. |
however, prior to employing neurons as a model in a dish, they need to be evaluated for their electrophysiological properties, including both passive and active membrane properties, dynamics of neurotransmitter release, and capacity to undergo synaptic plasticity. |
2015-06-05 |
2023-08-13 |
human |
| Anna Brachet, Stephanie Norwood, Jos F Brouwers, Ernest Palomer, J Bernd Helms, Carlos G Dotti, José A Esteba. LTP-triggered cholesterol redistribution activates Cdc42 and drives AMPA receptor synaptic delivery. The Journal of cell biology. vol 208. issue 6. 2015-05-26. PMID:25753037. |
neurotransmitter receptor trafficking during synaptic plasticity requires the concerted action of multiple signaling pathways and the protein transport machinery. |
2015-05-26 |
2023-08-13 |
Not clear |
| Jiang-Fan Che. Adenosine receptor control of cognition in normal and disease. International review of neurobiology. vol 119. 2015-05-12. PMID:25175970. |
thus, there is a convergence of the molecular studies revealing ar as molecular targets for integrating neurotransmitter signaling and controlling synaptic plasticity, with animal studies demonstrating the strong procognitive impact upon ar antagonism in normal and disease brains and with epidemiological and clinical evidences in support of caffeine and ar drugs for therapeutic modulation of cognition. |
2015-05-12 |
2023-08-13 |
human |
| Cornelius A Rietveld, Tõnu Esko, Gail Davies, Tune H Pers, Patrick Turley, Beben Benyamin, Christopher F Chabris, Valur Emilsson, Andrew D Johnson, James J Lee, Christiaan de Leeuw, Riccardo E Marioni, Sarah E Medland, Michael B Miller, Olga Rostapshova, Sven J van der Lee, Anna A E Vinkhuyzen, Najaf Amin, Dalton Conley, Jaime Derringer, Cornelia M van Duijn, Rudolf Fehrmann, Lude Franke, Edward L Glaeser, Narelle K Hansell, Caroline Hayward, William G Iacono, Carla Ibrahim-Verbaas, Vincent Jaddoe, Juha Karjalainen, David Laibson, Paul Lichtenstein, David C Liewald, Patrik K E Magnusson, Nicholas G Martin, Matt McGue, George McMahon, Nancy L Pedersen, Steven Pinker, David J Porteous, Danielle Posthuma, Fernando Rivadeneira, Blair H Smith, John M Starr, Henning Tiemeier, Nicholas J Timpson, Maciej Trzaskowski, André G Uitterlinden, Frank C Verhulst, Mary E Ward, Margaret J Wright, George Davey Smith, Ian J Deary, Magnus Johannesson, Robert Plomin, Peter M Visscher, Daniel J Benjamin, David Cesarini, Philipp D Koellinge. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 38. 2015-04-22. PMID:25201988. |
all of these genes are associated with a particular neurotransmitter pathway involved in synaptic plasticity, the main cellular mechanism for learning and memory. |
2015-04-22 |
2023-08-13 |
Not clear |
| Ege T Kavalal. The mechanisms and functions of spontaneous neurotransmitter release. Nature reviews. Neuroscience. vol 16. issue 1. 2015-02-17. PMID:25524119. |
a functional role for spontaneous neurotransmitter release events in the regulation of synaptic plasticity and homeostasis, as well as the regulation of certain behaviours, has been reported. |
2015-02-17 |
2023-08-13 |
Not clear |
| Mariana Postal, Simone Appenzelle. The importance of cytokines and autoantibodies in depression. Autoimmunity reviews. vol 14. issue 1. 2015-02-09. PMID:25242344. |
cytokines, such as tnf-α, play an important role in immune system; these cytokines interact with virtually every pathophysiologic domain relevant to depression, including neurotransmitter metabolism, neuroendocrine function, and synaptic plasticity. |
2015-02-09 |
2023-08-13 |
Not clear |
| Rafael T de Sousa, Marcus V Zanetti, Geraldo F Busatto, Margaret G Mouro, Carlos A Zarate, Wagner F Gattaz, Elisa M Higa, Rodrigo Machado-Vieir. Lithium increases nitric oxide levels in subjects with bipolar disorder during depressive episodes. Journal of psychiatric research. vol 55. 2015-01-07. PMID:24768108. |
altered nitric oxide (no) signaling has been associated with the pathophysiology of bipolar disorder (bd), directly affecting neurotransmitter release and synaptic plasticity cascades. |
2015-01-07 |
2023-08-13 |
human |
| Xiaofei Yang, Dongmei Hou, Wei Jiang, Chen Zhan. Intercellular protein-protein interactions at synapses. Protein & cell. vol 5. issue 6. 2015-01-06. PMID:24756565. |
the cam proteins link pre- and post-synaptic sites, and play essential roles in promoting synapse formation and maturation, maintaining synapse number and type, accumulating neurotransmitter receptors and ion channels, controlling neuronal differentiation, and even regulating synaptic plasticity directly. |
2015-01-06 |
2023-08-13 |
Not clear |
| Takeshi Kawauch. Cdk5 regulates multiple cellular events in neural development, function and disease. Development, growth & differentiation. vol 56. issue 5. 2015-01-05. PMID:24844647. |
furthermore, cdk5 is reported to control neurotransmitter release at presynaptic sites, endocytosis of the nmda receptor at postsynaptic sites and dendritic spine remodeling, and thereby regulate synaptic plasticity and memory formation and extinction. |
2015-01-05 |
2023-08-13 |
Not clear |
| Jérémie Sibille, Ulrike Pannasch, Nathalie Rouac. Astroglial potassium clearance contributes to short-term plasticity of synaptically evoked currents at the tripartite synapse. The Journal of physiology. vol 592. issue 1. 2014-11-11. PMID:24081156. |
although astrocytes express ionic channels, neurotransmitter receptors and transporters to detect neuronal activity, the nature, plasticity and impact of the currents induced by neuronal activity on short-term synaptic plasticity remain elusive in hippocampal astrocytes. |
2014-11-11 |
2023-08-12 |
mouse |
| Misa Arizono, Hiroko Bannai, Katsuhiko Mikoshib. Imaging mGluR5 dynamics in astrocytes using quantum dots. Current protocols in neuroscience. vol 66. 2014-10-23. PMID:24510777. |
qd-spt has been a powerful tool to examine the contribution of neurotransmitter receptor dynamics to synaptic plasticity. |
2014-10-23 |
2023-08-12 |
Not clear |
| Marco Segatto, Antonia Manduca, Claudio Lecis, Pamela Rosso, Adam Jozwiak, Ewa Swiezewska, Sandra Moreno, Viviana Trezza, Valentina Pallottin. Simvastatin treatment highlights a new role for the isoprenoid/cholesterol biosynthetic pathway in the modulation of emotional reactivity and cognitive performance in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 4. 2014-10-10. PMID:24108067. |
these effects are accompanied by imbalances in the activity of specific prenylated proteins, rab3 and rhoa, involved in neurotransmitter release, and synaptic plasticity, respectively. |
2014-10-10 |
2023-08-12 |
rat |
| Fernando Gutierrez-Fernandez, María Pinto-Gonzalez, Oscar Gonzalez-Pere. Neuro-immune interactions in the postnatal ventricular-subventricular zone. Journal of stem cells. vol 9. issue 1. 2014-09-30. PMID:25158089. |
as described in this book, the interaction between the immune system and the brain can affect multiple cerebral functions, such as: neural remodeling, synaptic plasticity or neurotransmitter releasing. |
2014-09-30 |
2023-08-13 |
Not clear |
| Shining Deng, Wei-Guang Li, Jing Ding, Jinlin Wu, Yuanyuan Zhang, Fei Li, Xiaoming She. Understanding the mechanisms of cognitive impairments in developmental coordination disorder. Pediatric research. vol 75. issue 1-2. 2014-09-29. PMID:24192703. |
this corresponds to changes in diverse brain regions, synaptic plasticity, and neurotransmitter and receptor activity during development under these effects. |
2014-09-29 |
2023-08-12 |
Not clear |
| Jie She. Function and dysfunction of presenilin. Neuro-degenerative diseases. vol 13. issue 2-3. 2014-09-23. PMID:24107444. |
in the central synapse, ps regulates neurotransmitter release, short- and long-term synaptic plasticity and calcium homeostasis. |
2014-09-23 |
2023-08-12 |
mouse |
| Silvia Giovedí, Anna Corradi, Anna Fassio, Fabio Benfenat. Involvement of synaptic genes in the pathogenesis of autism spectrum disorders: the case of synapsins. Frontiers in pediatrics. vol 2. 2014-09-19. PMID:25237665. |
syns are pre-synaptic proteins regulating synaptic vesicle traffic, neurotransmitter release, and short-term synaptic plasticity. |
2014-09-19 |
2023-08-13 |
mouse |
| Joan M Jasien, Caitlin M Daimon, Rui Wang, Bruce K Shapiro, Bronwen Martin, Stuart Maudsle. The effects of aging on the BTBR mouse model of autism spectrum disorder. Frontiers in aging neuroscience. vol 6. 2014-09-16. PMID:25225482. |
unbiased proteomic analysis of hippocampal and cortical tissue of btbr mice compared to age-matched wild-type controls revealed a significant decrease in brain derived neurotrophic factor and significant increases in multiple synaptic markers (spinophilin, synapsin i, psd 95, neun), as well as distinct changes in functional pathways related to these proteins, including "neural synaptic plasticity regulation" and "neurotransmitter secretion regulation." |
2014-09-16 |
2023-08-13 |
mouse |
| Jianyang Du, Leah R Reznikov, Margaret P Price, Xiang-ming Zha, Yuan Lu, Thomas O Moninger, John A Wemmie, Michael J Wels. Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 24. 2014-09-12. PMID:24889629. |
protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala. |
2014-09-12 |
2023-08-13 |
Not clear |