| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| André Jerónimo-Santos, João Fonseca-Gomes, Diogo Andrade Guimarães, Sara Ramalho Tanqueiro, Rita Mira Ramalho, Joaquim Alexandre Ribeiro, Ana Maria Sebastião, Maria José Diógene. Brain-derived neurotrophic factor mediates neuroprotection against Aβ-induced toxicity through a mechanism independent on adenosine 2A receptor activation. Growth factors (Chur, Switzerland). vol 33. issue 4. 2016-06-17. PMID:26365294. |
the activation of adenosine a2a receptors (a2ar) is essential for most of bdnf-mediated synaptic actions, such as synaptic plasticity, transmission and neurotransmitter release. |
2016-06-17 |
2023-08-13 |
Not clear |
| Kyle J Gerber, Katherine E Squires, John R Heple. Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity. Molecular pharmacology. vol 89. issue 2. 2016-05-13. PMID:26655302. |
at neuronal synapses, gpcrs, g proteins, and rgs proteins work in coordination to regulate key aspects of neurotransmitter release, synaptic transmission, and synaptic plasticity, which are necessary for central nervous system physiology and behavior. |
2016-05-13 |
2023-08-13 |
Not clear |
| Anders S Kristensen, Kasper B Hansen, Peter Naur, Lars Olsen, Natalie L Kurtkaya, Shashank M Dravid, Trine Kvist, Feng Yi, Jacob Pøhlsgaard, Rasmus P Clausen, Michael Gajhede, Jette S Kastrup, Stephen F Trayneli. Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors. Molecular pharmacology. vol 89. issue 2. 2016-05-13. PMID:26661043. |
the amino acid neurotransmitter d-ser is a glud2 receptor ligand, and endogenous d-ser signaling through glud2 has recently been shown to regulate endocytosis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type iglurs during synaptic plasticity in the cerebellum, such as long-term depression. |
2016-05-13 |
2023-08-13 |
Not clear |
| Diasynou Fioravante, YunXiang Chu, Arthur Ph de Jong, Michael Leitges, Pascal S Kaeser, Wade G Regeh. Protein kinase C is a calcium sensor for presynaptic short-term plasticity. eLife. vol 3. 2016-04-19. PMID:25097249. |
in presynaptic boutons, calcium (ca(2+)) triggers both neurotransmitter release and short-term synaptic plasticity. |
2016-04-19 |
2023-08-13 |
mouse |
| Luis Pérez de Sevilla Müller, Allison Sargoy, Laura Fernández-Sánchez, Allen Rodriguez, Janelle Liu, Nicolás Cuenca, Nicholas Brech. Expression and cellular localization of the voltage-gated calcium channel α2δ3 in the rodent retina. The Journal of comparative neurology. vol 523. issue 10. 2016-03-15. PMID:25631988. |
high-voltage-activated calcium channels are hetero-oligomeric protein complexes that mediate multiple cellular processes, including the influx of extracellular ca(2+), neurotransmitter release, gene transcription, and synaptic plasticity. |
2016-03-15 |
2023-08-13 |
mouse |
| Richard W Cho, Lauren K Buhl, Dina Volfson, Adrienne Tran, Feng Li, Yulia Akbergenova, J Troy Littleto. Phosphorylation of Complexin by PKA Regulates Activity-Dependent Spontaneous Neurotransmitter Release and Structural Synaptic Plasticity. Neuron. vol 88. issue 4. 2016-03-01. PMID:26590346. |
phosphorylation of complexin by pka regulates activity-dependent spontaneous neurotransmitter release and structural synaptic plasticity. |
2016-03-01 |
2023-08-13 |
drosophila_melanogaster |
| Puja K Parekh, Colleen A McClun. Circadian Mechanisms Underlying Reward-Related Neurophysiology and Synaptic Plasticity. Frontiers in psychiatry. vol 6. 2016-01-21. PMID:26793129. |
in this regard, several groups, including our own, have sought to understand how circadian proteins regulate mechanisms of synaptic plasticity and neurotransmitter signaling in mesocorticolimbic brain regions, which are known to be critically involved in reward processing and mood. |
2016-01-21 |
2023-08-13 |
Not clear |
| Michael A Gaviño, Kevin J Ford, Santiago Archila, Graeme W Davi. Homeostatic synaptic depression is achieved through a regulated decrease in presynaptic calcium channel abundance. eLife. vol 4. 2016-01-14. PMID:25884248. |
thus, we identify a novel mechanism of homeostatic synaptic plasticity and propose a model that can account for the observed bi-directional, homeostatic control of presynaptic neurotransmitter release. |
2016-01-14 |
2023-08-13 |
mouse |
| Parisa Esmaeili Tazangi, Seyed Mostafa Shid Moosavi, Mohamad Shabani, Masoud Haghan. Erythropoietin improves synaptic plasticity and memory deficits by decrease of the neurotransmitter release probability in the rat model of Alzheimer's disease. Pharmacology, biochemistry, and behavior. vol 130. 2015-12-23. PMID:25553822. |
erythropoietin improves synaptic plasticity and memory deficits by decrease of the neurotransmitter release probability in the rat model of alzheimer's disease. |
2015-12-23 |
2023-08-13 |
rat |
| Visakh Prabhakar, Deepali Gupta, Prateek Kanade, Mahesh Radhakrishna. Diabetes-associated depression: the serotonergic system as a novel multifunctional target. Indian journal of pharmacology. vol 47. issue 1. 2015-12-22. PMID:25821303. |
persisting hyperglycemia leads to impaired neurogenesis, decreased synaptic plasticity, undesired neuro-anatomical alterations, neurochemical deficits, and reduced neurotransmitter activity. |
2015-12-22 |
2023-08-13 |
Not clear |
| Nagore Puente, Leire Reguero, Izaskun Elezgarai, Miren-Josune Canduela, Juan Mendizabal-Zubiaga, Almudena Ramos-Uriarte, Emilio Fernández-Espejo, Pedro Grande. The transient receptor potential vanilloid-1 is localized at excitatory synapses in the mouse dentate gyrus. Brain structure & function. vol 220. issue 2. 2015-11-17. PMID:24487914. |
the transient receptor potential vanilloid type 1 (trpv1) is a non-selective cation channel that plays an important role in pain perception and modulates neurotransmitter release and synaptic plasticity in the brain. |
2015-11-17 |
2023-08-12 |
mouse |
| Norihito Shintani, Yusuke Onaka, Ryota Hashimoto, Hironori Takamura, Tsuyoshi Nagata, Satomi Umeda-Yano, Akihiro Mouri, Takayoshi Mamiya, Ryota Haba, Shinsuke Matsuzaki, Taiichi Katayama, Hidenaga Yamamori, Takanobu Nakazawa, Kazuki Nagayasu, Yukio Ago, Yuki Yagasaki, Toshitaka Nabeshima, Masatoshi Takeda, Hitoshi Hashimot. Behavioral characterization of mice overexpressing human dysbindin-1. Molecular brain. vol 7. 2015-11-10. PMID:25298178. |
the dysbindin-1 gene (dtnbp1: dystrobrevin binding protein 1) is a promising schizophrenia susceptibility gene, known to localize almost exclusively to neurons in the brain, and participates in the regulation of neurotransmitter release, membrane-surface receptor expression, and synaptic plasticity. |
2015-11-10 |
2023-08-13 |
mouse |
| Marco B Rus. ADF/cofilin: a crucial regulator of synapse physiology and behavior. Cellular and molecular life sciences : CMLS. vol 72. issue 18. 2015-11-10. PMID:26037722. |
hence, regulators of actin dynamics take a central role in mediating neurotransmitter release, synaptic plasticity, and ultimately behavior. |
2015-11-10 |
2023-08-13 |
Not clear |
| b' \\xc3\\x89 A Bukharaeva, E E Nikol\'ski\\xc4\\xa. [Changes in the kinetics of quanta secretion-effective mechanism of synaptic transmission modulation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 96. issue 8. 2015-10-26. PMID:20968062.' |
it is widely accepted that the leading presynaptic mechanisms underlying the synaptic plasticity involve changes of the number of neurotransmitter quanta released by one nerve pulse (the quantal content of postsynaptic response) and of the size of a single quantum. |
2015-10-26 |
2023-08-12 |
Not clear |
| b' \\xc3\\x89 A Bukharaeva, E E Nikol\'ski\\xc4\\xa. [Changes in the kinetics of quanta secretion-effective mechanism of synaptic transmission modulation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 96. issue 8. 2015-10-26. PMID:20968062.' |
in addition, the existence of one more effective though previously ignored mechanism of modulation of synaptic plasticity was suggested related to the change in the time course (kinetics) of secretion of single neurotransmitter quanta forming the multiquantal response. |
2015-10-26 |
2023-08-12 |
Not clear |
| Maureen H Richards, Srinivas D Narasipura, Stephanie Kim, Melanie S Seaton, Victoria Lutgen, Lena Al-Harth. Dynamic interaction between astrocytes and infiltrating PBMCs in context of neuroAIDS. Glia. vol 63. issue 3. 2015-09-21. PMID:25331637. |
the wnt pathway plays a vital role in the regulation of cns activities including neurogenesis, neurotransmitter release, synaptic plasticity, and memory consolidation. |
2015-09-21 |
2023-08-13 |
human |
| Gangsoo Jung, Eun-Jung Kim, Ana Cicvaric, Sunetra Sase, Marion Gröger, Harald Höger, Fernando Jayson Sialana, Johannes Berger, Francisco J Monje, Gert Lube. Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus. Journal of neurochemistry. vol 134. issue 2. 2015-09-14. PMID:25865831. |
drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus. |
2015-09-14 |
2023-08-13 |
mouse |
| Gangsoo Jung, Eun-Jung Kim, Ana Cicvaric, Sunetra Sase, Marion Gröger, Harald Höger, Fernando Jayson Sialana, Johannes Berger, Francisco J Monje, Gert Lube. Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus. Journal of neurochemistry. vol 134. issue 2. 2015-09-14. PMID:25865831. |
these findings provide unprecedented experimental support for a role of drebrin in the regulation of memory-related synaptic plasticity and neurotransmitter receptor signaling, offer relevant information regarding the interpretation of previous studies and help in the design of future studies on dendritic spines. |
2015-09-14 |
2023-08-13 |
mouse |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25146499. |
accordingly, we evaluated the effect of chronic reboxetine (a selective noradrenergic reuptake inhibitor) treatment on depression-induced reduced hippocampal synaptic plasticity, neurotransmitter levels, and spatial learning and memory impairments. |
2015-07-08 |
2023-08-13 |
rat |
| Akito Nakao, Takafumi Miki, Hirotaka Shoji, Miyuki Nishi, Hiroshi Takeshima, Tsuyoshi Miyakawa, Yasuo Mor. Comprehensive behavioral analysis of voltage-gated calcium channel beta-anchoring and -regulatory protein knockout mice. Frontiers in behavioral neuroscience. vol 9. 2015-07-03. PMID:26136667. |
calcium (ca(2+)) influx through voltage-gated ca(2+) channels (vgccs) induces numerous intracellular events such as neuronal excitability, neurotransmitter release, synaptic plasticity, and gene regulation. |
2015-07-03 |
2023-08-13 |
mouse |