| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yang Shen, Min Tian, Yuqiong Zheng, Fei Gong, Amy K Y Fu, Nancy Y I. Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer's Disease Model. Cell reports. vol 17. issue 7. 2017-11-20. PMID:27829153. |
although pro-opiomelanocortin (pomc)-derived neuropeptides and melanocortin 4 receptor (mc4r) are implicated in hippocampus-dependent synaptic plasticity, how the pomc/mc4r system functions in the hippocampus and its role in synaptic dysfunction in ad are largely unknown. |
2017-11-20 |
2023-08-13 |
mouse |
| Wendy A Koss, Karyn M Fric. Sex differences in hippocampal function. Journal of neuroscience research. vol 95. issue 1-2. 2017-11-13. PMID:27870401. |
this review will discuss seminal studies examining sex differences in hippocampal memory, neuronal morphology, synaptic plasticity, and cell signaling in humans and rodents. |
2017-11-13 |
2023-08-13 |
Not clear |
| David A Slattery, Katharina M Hillere. The maternal brain under stress: Consequences for adaptive peripartum plasticity and its potential functional implications. Frontiers in neuroendocrinology. vol 41. 2017-11-09. PMID:26828151. |
in addition to behavioural and physiological alterations, numerous brain regions, such as the medial prefrontal cortex, olfactory bulb, medial amygdala and hippocampus are subject to substantial peripartum-associated neuronal, dendritic and synaptic plasticity. |
2017-11-09 |
2023-08-13 |
human |
| Lorenzo Morè, Basil Künnecke, Latefa Yekhlef, Andreas Bruns, Antonella Marte, Ernesto Fedele, Veronica Bianchi, Stefano Taverna, Silvia Gatti, Patrizia D'Adam. Altered fronto-striatal functions in the Gdi1-null mouse model of X-linked Intellectual Disability. Neuroscience. vol 344. 2017-11-09. PMID:28057534. |
previous molecular and behavioral characterization of the gdi1-null mouse revealed alterations in the total number/distribution of hippocampal and cortical synaptic vesicles as well as hippocampal short-term synaptic plasticity, and memory deficits. |
2017-11-09 |
2023-08-13 |
mouse |
| Qin Li, Hai T Vo, Jing Wang, Stephanie Fox-Quick, Lynn E Dobrunz, Gwendalyn D Kin. Klotho regulates CA1 hippocampal synaptic plasticity. Neuroscience. vol 347. 2017-11-07. PMID:28215989. |
klotho regulates ca1 hippocampal synaptic plasticity. |
2017-11-07 |
2023-08-13 |
mouse |
| Qin Li, Hai T Vo, Jing Wang, Stephanie Fox-Quick, Lynn E Dobrunz, Gwendalyn D Kin. Klotho regulates CA1 hippocampal synaptic plasticity. Neuroscience. vol 347. 2017-11-07. PMID:28215989. |
we find that loss of klotho enhances both pre and post-synaptic measures of ca1 hippocampal synaptic plasticity at 5weeks of age. |
2017-11-07 |
2023-08-13 |
mouse |
| Qin Li, Hai T Vo, Jing Wang, Stephanie Fox-Quick, Lynn E Dobrunz, Gwendalyn D Kin. Klotho regulates CA1 hippocampal synaptic plasticity. Neuroscience. vol 347. 2017-11-07. PMID:28215989. |
klotho overexpressing mice show no early life effects on synaptic plasticity, but decreased ca1 hippocampal long-term potentiation was measured at 6months of age. |
2017-11-07 |
2023-08-13 |
mouse |
| Qin Li, Hai T Vo, Jing Wang, Stephanie Fox-Quick, Lynn E Dobrunz, Gwendalyn D Kin. Klotho regulates CA1 hippocampal synaptic plasticity. Neuroscience. vol 347. 2017-11-07. PMID:28215989. |
together these data suggest that klotho affects cognition, at least in part, by regulating hippocampal synaptic plasticity. |
2017-11-07 |
2023-08-13 |
mouse |
| Maryam Malek, Alireza Sarkaki, Saleh Zahedi-Asl, Yaghoob Farbood, Ziba Rajae. Effect of intra-hippocampal injection of human recombinant growth hormone on synaptic plasticity in the nucleus basalis magnocellularis-lesioned aged rats. Arquivos de neuro-psiquiatria. vol 75. issue 7. 2017-11-07. PMID:28746436. |
in this study, we proposed that administration of hippocampal growth hormone in ageing animals with growth hormone deficiency can compensate long-term potentiation and synaptic plasticity in nucleus basalis magnocellularis (nbm)-lesioned rats. |
2017-11-07 |
2023-08-13 |
human |
| Meina Wu, Yexin He, Jun Zhang, Junting Yang, Jinshun Q. Co-injection of Aβ1-40 and ApoE4 impaired spatial memory and hippocampal long-term potentiation in rats. Neuroscience letters. vol 648. 2017-11-06. PMID:28356228. |
in the present study, we examined the effects of apoe4 on the spatial memory and hippocampal long term potentiation (ltp) by using morris water maze test and in vivo field potential recording, compared the neurotoxicity of aβ1-40 and apoe4, and investigated the effects of co-application of aβ1-40 and apoe4 on cognitive behavior and synaptic plasticity. |
2017-11-06 |
2023-08-13 |
rat |
| Hui Zhang, Yingchun Shang, Xi Xiao, Mei Yu, Tao Zhan. Prenatal stress-induced impairments of cognitive flexibility and bidirectional synaptic plasticity are possibly associated with autophagy in adolescent male-offspring. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28882411. |
the bidirectional synaptic plasticity, including long-term potential (ltp) and depotentiation (dep), from the hippocampal schaffer collaterals to ca1 region was subsequently measured. |
2017-11-06 |
2023-08-13 |
rat |
| Ilaria Bertani, Valentina Iori, Massimo Trusel, Mattia Maroso, Claudia Foray, Susanna Mantovani, Raffaella Tonini, Annamaria Vezzani, Roberto Chies. Inhibition of IL-1β Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 43. 2017-11-06. PMID:28924012. |
to assess the potential involvement of nmda receptor (nmdar) dysfunction, we analyzed nmda-dependent synaptic plasticity in hippocampal slices from tg(cjd) mice, which model a genetic form of cjd. |
2017-11-06 |
2023-08-13 |
mouse |
| Andrea Aguilar-Arredondo, Fernanda López-Hernández, Lizbeth García-Velázquez, Clorinda Arias, Angélica Zeped. Behavior-associated Neuronal Activation After Kainic Acid-induced Hippocampal Neurotoxicity is Modulated in Time. Anatomical record (Hoboken, N.J. : 2007). vol 300. issue 2. 2017-11-03. PMID:27860379. |
kainic acid-induced (ka) hippocampal damage leads to neuronal death and further synaptic plasticity. |
2017-11-03 |
2023-08-13 |
rat |
| G Leal, C R Bramham, C B Duart. BDNF and Hippocampal Synaptic Plasticity. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215294. |
bdnf and hippocampal synaptic plasticity. |
2017-11-02 |
2023-08-13 |
Not clear |
| Maryam Nazari, Somaye Keshavarz, Ali Rafati, Mohammad Reza Namavar, Masoud Haghan. Fingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia. Brain research bulletin. vol 124. 2017-10-26. PMID:27066884. |
fingolimod (fty720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia. |
2017-10-26 |
2023-08-13 |
rat |
| Maryam Nazari, Somaye Keshavarz, Ali Rafati, Mohammad Reza Namavar, Masoud Haghan. Fingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia. Brain research bulletin. vol 124. 2017-10-26. PMID:27066884. |
therefore, the present study aimed to investigate the effects of fty720 on the impairment of learning and memory and hippocampal synaptic plasticity induced by middle cerebral artery occlusion (mcao) in ischemic brain injury. |
2017-10-26 |
2023-08-13 |
rat |
| Robbert Havekes, Alan J Park, Jennifer C Tudor, Vincent G Luczak, Rolf T Hansen, Sarah L Ferri, Vibeke M Bruinenberg, Shane G Poplawski, Jonathan P Day, Sara J Aton, Kasia Radwańska, Peter Meerlo, Miles D Houslay, George S Baillie, Ted Abe. Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. eLife. vol 5. 2017-10-23. PMID:27549340. |
suppression of cofilin function prevents spine loss, deficits in hippocampal synaptic plasticity, and impairments in long-term memory caused by sleep deprivation. |
2017-10-23 |
2023-08-13 |
mouse |
| Luis E B Bettio, Luckshi Rajendran, Joana Gil-Mohape. The effects of aging in the hippocampus and cognitive decline. Neuroscience and biobehavioral reviews. vol 79. 2017-10-23. PMID:28476525. |
neurobiological alterations seen in the aging hippocampus including increased oxidative stress and neuroinflammation, altered intracellular signalling and gene expression, as well as reduced neurogenesis and synaptic plasticity, are thought to be associated with age-related cognitive decline. |
2017-10-23 |
2023-08-13 |
Not clear |
| Sarah Hescham, Yasin Temel, Sandra Schipper, Mélanie Lagiere, Lisa-Maria Schönfeld, Arjan Blokland, Ali Jahanshah. Fornix deep brain stimulation induced long-term spatial memory independent of hippocampal neurogenesis. Brain structure & function. vol 222. issue 2. 2017-10-20. PMID:26832921. |
our results suggest that fornix dbs improves memory functions independent of hippocampal neurogenesis, possibly through other mechanisms such as synaptic plasticity and acute neurotransmitter release. |
2017-10-20 |
2023-08-13 |
rat |
| Shufang Feng, Tianyao Shi, Jiangxia Qiu, Haihong Yang, Yan Wu, Wenxia Zhou, Wei Wang, Haitao W. Notch1 deficiency in postnatal neural progenitor cells in the dentate gyrus leads to emotional and cognitive impairment. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 10. 2017-10-19. PMID:28611114. |
the latest evidence shows that notch1 also plays a critical role in synaptic plasticity in mature hippocampal neurons. |
2017-10-19 |
2023-08-13 |
Not clear |