| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Morgan S Bridi, Joshua D Hawk, Snehajyoti Chatterjee, Stephen Safe, Ted Abe. Pharmacological Activators of the NR4A Nuclear Receptors Enhance LTP in a CREB/CBP-Dependent Manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 6. 2018-01-19. PMID:27834392. |
we find that the 'c-dim' nr4a ligands, para-phenyl substituted di-indolylmethane compounds, enhance long-term contextual fear memory and increase the duration of long-term potentiation (ltp), a form of hippocampal synaptic plasticity. |
2018-01-19 |
2023-08-13 |
mouse |
| Magdalena Jasińska, Jacek Miłek, Iwona A Cymerman, Szymon Łęski, Leszek Kaczmarek, Magdalena Dziembowsk. miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA. Molecular neurobiology. vol 53. issue 7. 2018-01-16. PMID:26319558. |
furthermore, we demonstrate that the overexpression of mir-132 in the cultured hippocampal neurons from fmr1 ko mice that have increased synaptic mmp-9 level provokes enlargement of the dendritic spine heads, a process previously implicated in enhanced synaptic plasticity. |
2018-01-16 |
2023-08-13 |
mouse |
| Hui Gao, Peipei Yan, Shun Zhang, Hao Huang, Fenghong Huang, Taoping Sun, Qianchun Deng, Qingde Huang, Sijing Chen, Keqiang Ye, Jiqu Xu, Liegang Li. Long-Term Dietary Alpha-Linolenic Acid Supplement Alleviates Cognitive Impairment Correlate with Activating Hippocampal CREB Signaling in Natural Aging Rats. Molecular neurobiology. vol 53. issue 7. 2018-01-16. PMID:26328539. |
moreover, memory improvement was accompanied with alterations of hippocampal synaptic structure and number, suggestive of enhancement in synaptic plasticity. |
2018-01-16 |
2023-08-13 |
rat |
| Anne-Lieke F van Deijk, Nutabi Camargo, Jaap Timmerman, Tim Heistek, Jos F Brouwers, Floriana Mogavero, Huibert D Mansvelder, August B Smit, Mark H G Verheije. Astrocyte lipid metabolism is critical for synapse development and function in vivo. Glia. vol 65. issue 4. 2018-01-12. PMID:28168742. |
accordingly, hippocampal short-term and long-term synaptic plasticity were defective in mutant mice. |
2018-01-12 |
2023-08-13 |
mouse |
| Carmen Vivar, Benjamin D Peterson, Henriette van Praa. Running rewires the neuronal network of adult-born dentate granule cells. NeuroImage. vol 131. 2018-01-08. PMID:26589333. |
within ec afferent input and short-term synaptic plasticity from lateral entorhinal cortex, considered to convey contextual information to the hippocampus was increased. |
2018-01-08 |
2023-08-13 |
mouse |
| Janna Aarse, Stefan Herlitze, Denise Manahan-Vaugha. The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent. Hippocampus. vol 26. issue 6. 2018-01-08. PMID:26662461. |
the requirement of bdnf for hippocampal synaptic plasticity is experience-dependent. |
2018-01-08 |
2023-08-13 |
mouse |
| Janna Aarse, Stefan Herlitze, Denise Manahan-Vaugha. The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent. Hippocampus. vol 26. issue 6. 2018-01-08. PMID:26662461. |
in vitro, a specific role in hippocampal synaptic plasticity has been described, although not all experience-dependent forms of synaptic plasticity critically depend on bdnf. |
2018-01-08 |
2023-08-13 |
mouse |
| Yves Kellner, Steffen Fricke, Stella Kramer, Cristina Iobbi, Corette J Wierenga, Martin E Schwab, Martin Korte, Marta Zagrebelsk. Nogo-A controls structural plasticity at dendritic spines by rapidly modulating actin dynamics. Hippocampus. vol 26. issue 6. 2018-01-08. PMID:26748478. |
nogo-a and its receptors have been shown to control synaptic plasticity, including negatively regulating long-term potentiation (ltp) in the cortex and hippocampus at a fast time scale and restraining experience-dependent turnover of dendritic spines over days. |
2018-01-08 |
2023-08-13 |
Not clear |
| M R Penner, R R Parrish, L T Hoang, T L Roth, F D Lubin, C A Barne. Age-related changes in Egr1 transcription and DNA methylation within the hippocampus. Hippocampus. vol 26. issue 8. 2018-01-08. PMID:26972614. |
aged animals show functional alterations in hippocampal neurons that lead to deficits in synaptic plasticity and changes in cognitive function. |
2018-01-08 |
2023-08-13 |
Not clear |
| Manuel Rodriguez-Perdigon, Rosa María Tordera, Francisco Javier Gil-Bea, Gorka Gerenu, Maria Javier Ramirez, Maite Sola. Down-regulation of glutamatergic terminals (VGLUT1) driven by Aβ in Alzheimer's disease. Hippocampus. vol 26. issue 10. 2018-01-08. PMID:27258819. |
moreover, when aβ1-42 was intracerebroventricularlly administered into vglut1+/- mice, altered synaptic plasticity and increased neuroinflammation was observed in the hippocampus of those animals. |
2018-01-08 |
2023-08-13 |
mouse |
| Mark William Sherwood, Misa Arizono, Chihiro Hisatsune, Hiroko Bannai, Etsuko Ebisui, John Lawrence Sherwood, Aude Panatier, Stéphane Henri Richard Oliet, Katsuhiko Mikoshib. Astrocytic IP Glia. vol 65. issue 3. 2018-01-08. PMID:28063222. |
astrocytic ip astrocytes regulate hippocampal synaptic plasticity by the ca |
2018-01-08 |
2023-08-13 |
Not clear |
| Sebastian P Fernandez, Aude Muzerelle, Sophie Scotto-Lomassese, Jacques Barik, Agnès Gruart, José M Delgado-García, Patricia Gaspa. Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27461084. |
constitutive and acquired serotonin deficiency alters memory and hippocampal synaptic plasticity. |
2018-01-05 |
2023-08-13 |
mouse |
| Sebastian P Fernandez, Aude Muzerelle, Sophie Scotto-Lomassese, Jacques Barik, Agnès Gruart, José M Delgado-García, Patricia Gaspa. Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27461084. |
serotonergic projections from the median raphe are necessary to regulate object memory and hippocampal synaptic plasticity processes, through an inhibitory control mediated by 5-ht1a receptors. |
2018-01-05 |
2023-08-13 |
mouse |
| Ruud Zwart, Hannah Reed, Emanuele She. Oxotremorine-M potentiates NMDA receptors by muscarinic receptor dependent and independent mechanisms. Biochemical and biophysical research communications. vol 495. issue 1. 2018-01-05. PMID:29127015. |
muscarinic acetylcholine m1 receptors play an important role in synaptic plasticity in the hippocampus and cortex. |
2018-01-05 |
2023-08-13 |
human |
| Wanting Dong, Dan Xu, Zewen Hu, Xia He, Zijing Guo, Zhexiao Jiao, Ying Yu, Hui Wan. Low-functional programming of the CREB/BDNF/TrkB pathway mediates cognitive impairment in male offspring after prenatal dexamethasone exposure. Toxicology letters. vol 283. 2018-01-04. PMID:29111458. |
the adult pde male offspring rats exhibited cognitive impairment, decreased cell proliferation and increased cell apoptosis in the hippocampus, along with damaged synaptic plasticity and disrupted protein synthesis. |
2018-01-04 |
2023-08-13 |
rat |
| Birgit Rössner, Maximilian Klingler, Tanja Bulat, Ajinkya Sase, Andrea Zeilinger, Melanie Spitzwieser, Jana Aradska, Margit Cichna-Markl, Gert Lube. Hippocampal GluA2 and GluA4 protein but not corresponding mRNA and promoter methylation levels are modulated at retrieval in spatial learning of the rat. Amino acids. vol 49. issue 1. 2018-01-01. PMID:27714514. |
results obtained with the morris water maze (mwm), a paradigm for testing spatial memory in rodent, correlate with hippocampal synaptic plasticity and nmda function. |
2018-01-01 |
2023-08-13 |
rat |
| Tao Wang, Rui-Li Guan, Ming-Chao Liu, Xue-Feng Shen, Jing Yuan Chen, Ming-Gao Zhao, Wen-Jing Lu. Lead Exposure Impairs Hippocampus Related Learning and Memory by Altering Synaptic Plasticity and Morphology During Juvenile Period. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26141123. |
lead exposure impairs hippocampus related learning and memory by altering synaptic plasticity and morphology during juvenile period. |
2017-12-29 |
2023-08-13 |
rat |
| YuanBo Cui, ShanShan Ma, ChunYan Zhang, Wei Cao, Min Liu, DongPeng Li, PengJu Lv, Qu Xing, RuiNa Qu, Ning Yao, Bo Yang, FangXia Gua. Human umbilical cord mesenchymal stem cells transplantation improves cognitive function in Alzheimer's disease mice by decreasing oxidative stress and promoting hippocampal neurogenesis. Behavioural brain research. vol 320. 2017-12-27. PMID:28007537. |
the mechanisms underlying the improved cognitive function may be linked to hippocampal neurogenesis and an up-regulation of neuronal synaptic plasticity related proteins levels including silent information regulator 1 (sirt1), brain-derived neurotrophic factor (bdnf) and synaptophysin (syn). |
2017-12-27 |
2023-08-13 |
mouse |
| F Coune, B Silvestre de Ferron, M C González-Marín, J Antol, M Naassila, O Pierrefich. Resistance to ethanol sensitization is associated with a loss of synaptic plasticity in the hippocampus. Synapse (New York, N.Y.). vol 71. issue 2. 2017-12-22. PMID:26898905. |
resistance to ethanol sensitization is associated with a loss of synaptic plasticity in the hippocampus. |
2017-12-22 |
2023-08-13 |
mouse |
| F Coune, B Silvestre de Ferron, M C González-Marín, J Antol, M Naassila, O Pierrefich. Resistance to ethanol sensitization is associated with a loss of synaptic plasticity in the hippocampus. Synapse (New York, N.Y.). vol 71. issue 2. 2017-12-22. PMID:26898905. |
although the literature indicated that the hippocampus may play a role in etoh sensitization, it is not known whether behavioral sensitization to etoh is associated with preferential changes in bidirectional synaptic plasticity, i.e., ltp and ltd, two markers of learning capabilities that have also been shown to be involved in addictive behavior. |
2017-12-22 |
2023-08-13 |
mouse |