All Relations between synaptic plasticity and hippocampus

Publication Sentence Publish Date Extraction Date Species
Xia Tian, Yanlin Liu, Guangwei Ren, Ling Yin, Xiaoyan Liang, Tao Geng, Heqin Dang, Rufeng A. Resveratrol limits diabetes-associated cognitive decline in rats by preventing oxidative stress and inflammation and modulating hippocampal structural synaptic plasticity. Brain research. vol 1650. 2017-08-21. PMID:27566063. therefore, we tested its influence against cognitive dysfunction as well as on hippocampal structural synaptic plasticity in streptozotocin-induced diabetic rats. 2017-08-21 2023-08-13 rat
Olena Bukalo, Philip R Lee, R Douglas Field. BDNF mRNA abundance regulated by antidromic action potentials and AP-LTD in hippocampus. Neuroscience letters. vol 635. 2017-08-15. PMID:27760383. action-potential-induced ltd (ap-ltd) is a form of synaptic plasticity that reduces synaptic strength in ca1 hippocampal neurons firing antidromically during sharp-wave ripples. 2017-08-15 2023-08-13 mouse
Nasrin Hosseini, Hojjatollah Alaei, Parham Reisi, Maryam Radahmad. The effects of NBM- lesion on synaptic plasticity in rats. Brain research. vol 1655. 2017-08-08. PMID:27867034. hence, this study was devoted to the assessment of the effects of bilateral lesion of the nbm on synaptic plasticity in the dentate gyrus of the hippocampus using electrophysiological techniques. 2017-08-08 2023-08-13 rat
Jiandong Sun, Yan Liu, Jennifer Tran, Patrick O'Neal, Michel Baudry, Xiaoning B. mTORC1-S6K1 inhibition or mTORC2 activation improves hippocampal synaptic plasticity and learning in Angelman syndrome mice. Cellular and molecular life sciences : CMLS. vol 73. issue 22. 2017-08-04. PMID:27173058. mtorc1-s6k1 inhibition or mtorc2 activation improves hippocampal synaptic plasticity and learning in angelman syndrome mice. 2017-08-04 2023-08-13 mouse
Mónica Fernández-Monreal, Carla Sánchez-Castillo, José A Esteba. APPL1 gates long-term potentiation through its plekstrin homology domain. Journal of cell science. vol 129. issue 14. 2017-08-04. PMID:27257087. hippocampal synaptic plasticity involves both membrane trafficking events and intracellular signaling, but how these are coordinated is far from clear. 2017-08-04 2023-08-13 Not clear
Mahesh Shivarama Shetty, Sreedharan Sajikuma. 'Tagging' along memories in aging: Synaptic tagging and capture mechanisms in the aged hippocampus. Ageing research reviews. vol 35. 2017-08-02. PMID:28065806. hippocampal synaptic plasticity, such as long-term potentiation (ltp) and depression (ltd), are candidate cellular correlates of learning and memory and alterations in these properties have been well documented in aging. 2017-08-02 2023-08-13 Not clear
Yong Liu, Li-Jun Zhou, Jun Wang, Dai Li, Wen-Jie Ren, Jiyun Peng, Xiao Wei, Ting Xu, Wen-Jun Xin, Rui-Ping Pang, Yong-Yong Li, Zhi-Hai Qin, Madhuvika Murugan, Mark P Mattson, Long-Jun Wu, Xian-Guo Li. TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 4. 2017-08-01. PMID:28123022. tnf-α differentially regulates synaptic plasticity in the hippocampus and spinal cord by microglia-dependent mechanisms after peripheral nerve injury. 2017-08-01 2023-08-13 mouse
Rahul Agrawal, Emily Noble, Laurent Vergnes, Zhe Ying, Karen Reue, Fernando Gomez-Pinill. Dietary fructose aggravates the pathobiology of traumatic brain injury by influencing energy homeostasis and plasticity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 36. issue 5. 2017-07-31. PMID:26661172. here we report that fructose consumption disrupts hippocampal energy homeostasis as evidenced by a decline in functional mitochondria bioenergetics (oxygen consumption rate and cytochrome c oxidase activity) and an aggravation of the effects of traumatic brain injury on molecular systems engaged in cell energy homeostasis (sirtuin 1, peroxisome proliferator-activated receptor gamma coactivator-1alpha) and synaptic plasticity (brain-derived neurotrophic factor, tropomyosin receptor kinase b, cyclic adenosine monophosphate response element binding, synaptophysin signaling). 2017-07-31 2023-08-13 Not clear
Kristina Lippmann, Lyn Kamintsky, Soo Young Kim, Svetlana Lublinsky, Ofer Prager, Julia Friederike Nichtweiss, Seda Salar, Daniela Kaufer, Uwe Heinemann, Alon Friedma. Epileptiform activity and spreading depolarization in the blood-brain barrier-disrupted peri-infarct hippocampus are associated with impaired GABAergic inhibition and synaptic plasticity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 37. issue 5. 2017-07-31. PMID:27252228. epileptiform activity and spreading depolarization in the blood-brain barrier-disrupted peri-infarct hippocampus are associated with impaired gabaergic inhibition and synaptic plasticity. 2017-07-31 2023-08-13 rat
Ruchi Malik, Daniel Johnsto. Dendritic GIRK Channels Gate the Integration Window, Plateau Potentials, and Induction of Synaptic Plasticity in Dorsal But Not Ventral CA1 Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 14. 2017-07-27. PMID:28280255. in this study, we tested this hypothesis by quantifying the differences in dendritic integration and synaptic plasticity between dorsal and ventral ca1 pyramidal neurons of rat hippocampus. 2017-07-27 2023-08-13 rat
Liana R Stein, Kazuko A O'Dell, Michiyo Funatsu, Charles F Zorumski, Yukitoshi Izum. Short-term environmental enrichment enhances synaptic plasticity in hippocampal slices from aged rats. Neuroscience. vol 329. 2017-07-26. PMID:27208617. short-term environmental enrichment enhances synaptic plasticity in hippocampal slices from aged rats. 2017-07-26 2023-08-13 rat
Feng Zhao, Jing Li, Linlong Mo, Min Tan, Ting Zhang, Yong Tang, Yuanyu Zha. Changes in Neurons and Synapses in Hippocampus of Streptozotocin-Induced Type 1 Diabetes Rats: A Stereological Investigation. Anatomical record (Hoboken, N.J. : 2007). vol 299. issue 9. 2017-07-24. PMID:27064698. previous studies have indicated that diabetes could cause hippocampus atrophy, neuron loss, and synaptic plasticity impairment. 2017-07-24 2023-08-13 rat
Bruce C Kennedy, Jiva G Dimova, Srikanth Dakoji, Li-Lian Yuan, Jonathan C Gewirtz, Phu V Tra. Deletion of novel protein TMEM35 alters stress-related functions and impairs long-term memory in mice. American journal of physiology. Regulatory, integrative and comparative physiology. vol 311. issue 1. 2017-07-24. PMID:27170659. to identify putative molecular pathways underlying alterations in plasticity, proteomic analysis of synaptosomal proteins revealed lower levels of postsynaptic molecules important for synaptic plasticity in the ko hippocampus, including psd95 and n-methyl-d-aspartate receptors. 2017-07-24 2023-08-13 mouse
Ting Yang, Shaomin Li, Huixin Xu, Dominic M Walsh, Dennis J Selko. Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 1. 2017-07-24. PMID:28053038. soluble oligomers of amyloid β-protein (oaβ) isolated from the brains of alzheimer's disease (ad) patients have been shown experimentally (in the absence of amyloid plaques) to impair hippocampal synaptic plasticity, decrease synapses, induce tau hyperphosphorylation and neuritic dystrophy, activate microglial inflammation, and impair memory in normal adult rodents. 2017-07-24 2023-08-13 mouse
David J Titus, Nicole M Wilson, Julie E Freund, Melissa M Carballosa, Kevin E Sikah, Concepcion Furones, W Dalton Dietrich, Mark E Gurney, Coleen M Atkin. Chronic Cognitive Dysfunction after Traumatic Brain Injury Is Improved with a Phosphodiesterase 4B Inhibitor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 27. 2017-07-18. PMID:27383587. these results suggest that a subtype-selective pde4b inhibitor is a potential therapeutic to reverse chronic learning and memory dysfunction and deficits in hippocampal synaptic plasticity following tbi. 2017-07-18 2023-08-13 rat
Lanting Huang, Xiu-Juan Yang, Ying Huang, Eve Y Sun, Mu Su. Ketamine Protects Gamma Oscillations by Inhibiting Hippocampal LTD. PloS one. vol 11. issue 7. 2017-07-18. PMID:27467732. ketamine protects gamma oscillations by inhibiting hippocampal ltd. nmda receptors have been widely reported to be involved in the regulation of synaptic plasticity through effects on long-term potentiation (ltp) and long-term depression (ltd). 2017-07-18 2023-08-13 mouse
Robbert Havekes, Alan J Park, Rosa E Tolentino, Vibeke M Bruinenberg, Jennifer C Tudor, Yool Lee, Rolf T Hansen, Leonardo A Guercio, Edward Linton, Susana R Neves-Zaph, Peter Meerlo, George S Baillie, Miles D Houslay, Ted Abe. Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2017-07-17. PMID:27559174. compartmentalized pde4a5 signaling impairs hippocampal synaptic plasticity and long-term memory. 2017-07-17 2023-08-13 mouse
Robbert Havekes, Alan J Park, Rosa E Tolentino, Vibeke M Bruinenberg, Jennifer C Tudor, Yool Lee, Rolf T Hansen, Leonardo A Guercio, Edward Linton, Susana R Neves-Zaph, Peter Meerlo, George S Baillie, Miles D Houslay, Ted Abe. Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2017-07-17. PMID:27559174. however, the functional role of specific compartmentalized pde4 isoforms has not been examined in vivo here, we show that increasing protein levels of the pde4a5 isoform in mouse hippocampal excitatory neurons impairs a long-lasting form of hippocampal synaptic plasticity and attenuates hippocampus-dependent long-term memories without affecting anxiety. 2017-07-17 2023-08-13 mouse
Lars Fester, Lepu Zhou, Christiana Ossig, Jan Labitzke, Corinna Bläute, Manuela Bader, Günter Vollmer, Hubertus Jarry, Gabriele M Run. Synaptopodin is regulated by aromatase activity. Journal of neurochemistry. vol 140. issue 1. 2017-07-13. PMID:27861893. locally synthesized estradiol plays an important role in synaptic plasticity in the hippocampus. 2017-07-13 2023-08-13 Not clear
Xin Wu, Jie-Ting Zhang, Di Li, Jun Zhou, Jun Yang, Hui-Ling Zheng, Jian-Guo Chen, Fang Wan. Aquaporin-4 deficiency facilitates fear memory extinction in the hippocampus through excessive activation of extrasynaptic GluN2B-containing NMDA receptors. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27373674. however, little is known about the function of aqp-4 for synaptic plasticity in the hippocampus. 2017-07-11 2023-08-13 mouse