| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wolfgang Jacob, Rudolph Marsch, Giovanni Marsicano, Beat Lutz, Carsten T Wotja. Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo. Neurobiology of learning and memory. vol 98. issue 1. 2012-12-03. PMID:22579951. |
in the present study, the role of cb1 was investigated in three different hippocampus-dependent memory tasks and in in vivo hippocampal synaptic plasticity in knockout (cb1-ko) and wildtype mice. |
2012-12-03 |
2023-08-12 |
mouse |
| Wolfgang Jacob, Rudolph Marsch, Giovanni Marsicano, Beat Lutz, Carsten T Wotja. Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo. Neurobiology of learning and memory. vol 98. issue 1. 2012-12-03. PMID:22579951. |
in conclusion, cb1 deficiency leads to enhanced contextual fear memory and altered synaptic plasticity in the hippocampus, supporting the key role of endocannabinoid signalling in learning and memory, in particular following highly aversive encounters. |
2012-12-03 |
2023-08-12 |
mouse |
| Y Yamazaki, S Fujii, T Aihara, K Mikoshib. Activation of inositol 1, 4, 5-trisphosphate receptors during preconditioning low-frequency stimulation leads to reversal of long-term potentiation in hippocampal CA1 neurons. Neuroscience. vol 207. 2012-11-27. PMID:22330836. |
we investigated the role of inositol 1, 4, 5-trisphosphate receptors (ip3rs) that were activated during preconditioning low-frequency afferent stimulation (lfs) in the subsequent induction of synaptic plasticity in ca1 neurons in hippocampal slices from mature guinea pigs. |
2012-11-27 |
2023-08-12 |
Not clear |
| Yuan Yang, Gui-Jing Xiong, Da-Fu Yu, Jun Cao, Li-Ping Wang, Lin Xu, Rong-Rong Ma. Acute low-dose melamine affects hippocampal synaptic plasticity and behavior in rats. Toxicology letters. vol 214. issue 1. 2012-11-27. PMID:22922007. |
acute low-dose melamine affects hippocampal synaptic plasticity and behavior in rats. |
2012-11-27 |
2023-08-12 |
human |
| Yuan Yang, Gui-Jing Xiong, Da-Fu Yu, Jun Cao, Li-Ping Wang, Lin Xu, Rong-Rong Ma. Acute low-dose melamine affects hippocampal synaptic plasticity and behavior in rats. Toxicology letters. vol 214. issue 1. 2012-11-27. PMID:22922007. |
here, we aimed to examine the effects of acute low-dose exposure to melamine on hippocampal synaptic plasticity and behaviors in rats. |
2012-11-27 |
2023-08-12 |
human |
| Yuan Yang, Gui-Jing Xiong, Da-Fu Yu, Jun Cao, Li-Ping Wang, Lin Xu, Rong-Rong Ma. Acute low-dose melamine affects hippocampal synaptic plasticity and behavior in rats. Toxicology letters. vol 214. issue 1. 2012-11-27. PMID:22922007. |
our findings reveal some of the aspects of neurotoxicity induced by acute low-dose of melamine in hippocampal synaptic plasticity and behavior. |
2012-11-27 |
2023-08-12 |
human |
| Seong S Shim, Michael D Hammonds, Curtis Tatsuoka, I Jung Fen. Effects of 4-weeks of treatment with lithium and olanzapine on long-term potentiation in hippocampal area CA1. Neuroscience letters. vol 524. issue 1. 2012-11-21. PMID:22750162. |
in the present study, to examine the effects of lithium and olanzapine on synaptic plasticity, we examined the effects of chronic treatment with lithium and olanzapine on long-term potentiation (ltp) and input and output (i/o) responses of field excitatory postsynaptic potentials (fepsp) of ca1 pyramidal cells in hippocampal slices prepared from rats administered the drugs for 4 weeks. |
2012-11-21 |
2023-08-12 |
rat |
| Seong S Shim, Michael D Hammonds, Curtis Tatsuoka, I Jung Fen. Effects of 4-weeks of treatment with lithium and olanzapine on long-term potentiation in hippocampal area CA1. Neuroscience letters. vol 524. issue 1. 2012-11-21. PMID:22750162. |
the results suggest that lithium up-regulates synaptic plasticity in the hippocampus, and olanzapine increases synaptic transmission without apparent changes in ltp in the hippocampus. |
2012-11-21 |
2023-08-12 |
rat |
| T E Nelson, A Olde Engberink, R Hernandez, A Puro, S Huitron-Resendiz, C Hao, P N E De Graan, D L Gruo. Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6. Brain, behavior, and immunity. vol 26. issue 6. 2012-11-20. PMID:22609298. |
no differences were observed for several forms of short-term and long-term synaptic plasticity between hippocampal slices from il-6 tg and non-tg mice. |
2012-11-20 |
2023-08-12 |
mouse |
| Mark William Lopes, Flávia Mahatma Schneider Soares, Nelson de Mello, Jean Costa Nunes, Fabiano Mendes de Cordova, Roger Walz, Rodrigo Bainy Lea. Time-dependent modulation of mitogen activated protein kinases and AKT in rat hippocampus and cortex in the pilocarpine model of epilepsy. Neurochemical research. vol 37. issue 9. 2012-11-20. PMID:22614924. |
mitogen-activated protein kinases (mapks) and akt may be activated by diverse stimulus including neurotransmitter, oxidative stress, growth factors and cytokines and are involved in synaptic plasticity in the hippocampus and cerebral cortex. |
2012-11-20 |
2023-08-12 |
rat |
| Mark I Ransome, Thibault Renoir, Anthony J Hanna. Hippocampal neurogenesis, cognitive deficits and affective disorder in Huntington's disease. Neural plasticity. vol 2012. 2012-11-20. PMID:22830053. |
the discovery, in multiple transgenic lines of hd mice, that adult hippocampal neurogenesis and synaptic plasticity is disrupted, may help explain specific aspects of cognitive and affective dysfunction. |
2012-11-20 |
2023-08-12 |
mouse |
| Nathan Cramer, Zygmunt Galdzick. From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome. Neural plasticity. vol 2012. 2012-11-20. PMID:22848844. |
from abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome. |
2012-11-20 |
2023-08-12 |
mouse |
| Markus Heinen, Moritz M Hettich, Devon P Ryan, Susanne Schnell, Katharina Paesler, Dan Ehninge. Adult-onset fluoxetine treatment does not improve behavioral impairments and may have adverse effects on the Ts65Dn mouse model of Down syndrome. Neural plasticity. vol 2012. 2012-11-20. PMID:22848851. |
in the ts65dn mouse model of down syndrome, excessive gabaergic neurotransmission results in local over-inhibition of hippocampal circuits, which dampens hippocampal synaptic plasticity and contributes to cognitive impairments. |
2012-11-20 |
2023-08-12 |
mouse |
| Etsuko Suzuki, Takashi Okad. Stratum oriens stimulation-evoked modulation of hippocampal long-term potentiation involves the activation of muscarinic acetylcholine receptors and the inhibition of Kv7/M potassium ion channels. The European journal of neuroscience. vol 36. issue 1. 2012-11-19. PMID:22639893. |
acetylcholine is considered to be an endogenous modulator of hippocampal neurotransmission and synaptic plasticity. |
2012-11-19 |
2023-08-12 |
rat |
| Etsuko Suzuki, Takashi Okad. Stratum oriens stimulation-evoked modulation of hippocampal long-term potentiation involves the activation of muscarinic acetylcholine receptors and the inhibition of Kv7/M potassium ion channels. The European journal of neuroscience. vol 36. issue 1. 2012-11-19. PMID:22639893. |
the activation of muscarinic acetylcholine receptors (machrs) reportedly enhances hippocampal synaptic plasticity, which plays an important role in memory function; however, the mechanism by which it enhances synaptic plasticity remains unclear. |
2012-11-19 |
2023-08-12 |
rat |
| Megha Maheshwari, Ananya Samanta, Swetha K Godavarthi, Rajarshi Mukherjee, Nihar Ranjan Jan. Dysfunction of the ubiquitin ligase Ube3a may be associated with synaptic pathophysiology in a mouse model of Huntington disease. The Journal of biological chemistry. vol 287. issue 35. 2012-11-19. PMID:22787151. |
interestingly, arc, one of the substrates of ube3a linked with synaptic plasticity, is also associated with nuclear aggregates, although its synaptic level is increased in the hippocampus and cortex of hd mouse brain. |
2012-11-19 |
2023-08-12 |
mouse |
| Zhenglin Gu, Patricia W Lamb, Jerrel L Yake. Cholinergic coordination of presynaptic and postsynaptic activity induces timing-dependent hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 36. 2012-11-16. PMID:22956824. |
cholinergic coordination of presynaptic and postsynaptic activity induces timing-dependent hippocampal synaptic plasticity. |
2012-11-16 |
2023-08-12 |
mouse |
| Zhenglin Gu, Patricia W Lamb, Jerrel L Yake. Cholinergic coordination of presynaptic and postsynaptic activity induces timing-dependent hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 36. 2012-11-16. PMID:22956824. |
correlated cholinergic input induces spike timing-dependent plasticity-like hippocampal synaptic plasticity. |
2012-11-16 |
2023-08-12 |
mouse |
| Anne Kemp, Denise Manahan-Vaugha. Passive spatial perception facilitates the expression of persistent hippocampal long-term depression. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 7. 2012-11-13. PMID:21917740. |
learning-facilitated plasticity describes the ability of hippocampal synapses to respond with synaptic plasticity when weak afferent stimulation is coupled with a spatial learning event. |
2012-11-13 |
2023-08-12 |
rat |
| Grzegorz Wiera, Tomasz Wójtowicz, Katarzyna Lebida, Aleksandra Piotrowska, Dominika Drulis-Fajdasz, Agnieszka Gomułkiewicz, Daria Gendosz, Marzena Podhorska-Okołów, Marco Capogna, Grzegorz Wilczyński, Piotr Dzięgiel, Leszek Kaczmarek, Jerzy W Mozrzyma. Long term potentiation affects intracellular metalloproteinases activity in the mossy fiber-CA3 pathway. Molecular and cellular neurosciences. vol 50. issue 2. 2012-11-09. PMID:22555058. |
in the last decade, studies carried out mainly on the schaffer collateral-ca1 hippocampal projection have provided solid evidence that mmps regulate synaptic plasticity and learning. |
2012-11-09 |
2023-08-12 |
Not clear |