| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jana Doehner, Christel Genoud, Claudine Imhof, Dimitrije Krstic, Irene Knuese. Extrusion of misfolded and aggregated proteins--a protective strategy of aging neurons? The European journal of neuroscience. vol 35. issue 12. 2012-11-09. PMID:22708604. |
this hypothesis emerged from our previous investigations of the aged hippocampus revealing layer-specific accumulations of reelin, a glycoprotein with fundamental roles during brain development and adult synaptic plasticity. |
2012-11-09 |
2023-08-12 |
mouse |
| Amer Kamal, Geert M J Ramakers, Willem Hendrik Gispen, Geert Jan Biessel. Effect of chronic intracerebroventricular insulin administration in rats on the peripheral glucose metabolism and synaptic plasticity of CA1 hippocampal neurons. Brain research. vol 1435. 2012-11-07. PMID:22206925. |
effect of chronic intracerebroventricular insulin administration in rats on the peripheral glucose metabolism and synaptic plasticity of ca1 hippocampal neurons. |
2012-11-07 |
2023-08-12 |
rat |
| Amer Kamal, Geert M J Ramakers, Willem Hendrik Gispen, Geert Jan Biessel. Effect of chronic intracerebroventricular insulin administration in rats on the peripheral glucose metabolism and synaptic plasticity of CA1 hippocampal neurons. Brain research. vol 1435. 2012-11-07. PMID:22206925. |
in this study we examined the effects of sustained intracerebroventricular insulin infusion on hippocampal synaptic plasticity in rats. |
2012-11-07 |
2023-08-12 |
rat |
| Ruchi Malik, Sumantra Chattarj. Enhanced intrinsic excitability and EPSP-spike coupling accompany enriched environment-induced facilitation of LTP in hippocampal CA1 pyramidal neurons. Journal of neurophysiology. vol 107. issue 5. 2012-11-06. PMID:22157122. |
here, using whole-cell recordings in hippocampal slices, we address this gap by analyzing the impact of ee on both synaptic plasticity and intrinsic excitability of hippocampal ca1 pyramidal neurons. |
2012-11-06 |
2023-08-12 |
Not clear |
| Noelia Madroñal, Agnès Gruart, Olga Valverde, Isabel Espadas, Rosario Moratalla, José M Delgado-Garcí. Involvement of cannabinoid CB1 receptor in associative learning and in hippocampal CA3-CA1 synaptic plasticity. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 3. 2012-11-01. PMID:21673070. |
involvement of cannabinoid cb1 receptor in associative learning and in hippocampal ca3-ca1 synaptic plasticity. |
2012-11-01 |
2023-08-12 |
mouse |
| Heidi Anthoni, Lara E Sucheston, Barbara A Lewis, Isabel Tapia-Páez, Xiaotang Fan, Marco Zucchelli, Mikko Taipale, Catherine M Stein, Marie-Estelle Hokkanen, Eero Castrén, Bruce F Pennington, Shelley D Smith, Richard K Olson, J Bruce Tomblin, Gerd Schulte-Körne, Markus Nöthen, Johannes Schumacher, Bertram Müller-Myhsok, Per Hoffmann, Jeffrey W Gilger, George W Hynd, Jaana Nopola-Hemmi, Paavo H T Leppanen, Heikki Lyytinen, Jacqueline Schoumans, Magnus Nordenskjöld, Jason Spencer, Davor Stanic, Wah Chin Boon, Evan Simpson, Sari Mäkelä, Jan-Åke Gustafsson, Myriam Peyrard-Janvid, Sudha Iyengar, Juha Ker. The aromatase gene CYP19A1: several genetic and functional lines of evidence supporting a role in reading, speech and language. Behavior genetics. vol 42. issue 4. 2012-11-01. PMID:22426781. |
local estrogen synthesis in the hippocampus regulates synaptic plasticity and axonal growth); it is involved in sexual differentiation of the brain; and in songbirds and teleost fishes, it regulates vocalization. |
2012-11-01 |
2023-08-12 |
mouse |
| Masanori Nomoto, Yohei Takeda, Shusaku Uchida, Koji Mitsuda, Hatsune Enomoto, Kaori Saito, Tesu Choi, Ayako M Watabe, Shizuka Kobayashi, Shoichi Masushige, Toshiya Manabe, Satoshi Kid. Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity. Molecular brain. vol 5. 2012-10-31. PMID:22316320. |
dysfunction of the rar/rxr signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity. |
2012-10-31 |
2023-08-12 |
mouse |
| Masanori Nomoto, Yohei Takeda, Shusaku Uchida, Koji Mitsuda, Hatsune Enomoto, Kaori Saito, Tesu Choi, Ayako M Watabe, Shizuka Kobayashi, Shoichi Masushige, Toshiya Manabe, Satoshi Kid. Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity. Molecular brain. vol 5. 2012-10-31. PMID:22316320. |
retinoid signaling pathways mediated by retinoic acid receptor (rar)/retinoid × receptor (rxr)-mediated transcription play critical roles in hippocampal synaptic plasticity. |
2012-10-31 |
2023-08-12 |
mouse |
| Jian-Yi Xu, Jian Zhang, Chu Che. Long-lasting potentiation of hippocampal synaptic transmission by direct cortical input is mediated via endocannabinoids. The Journal of physiology. vol 590. issue 10. 2012-10-25. PMID:22411015. |
direct cortical inputs to ca1 pyramidal neurons through the pp provide instructive signals for hippocampal long-term synaptic plasticity. |
2012-10-25 |
2023-08-12 |
Not clear |
| Sarah M Rothman, Kathleen J Griffioen, Ruiqian Wan, Mark P Mattso. Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health. Annals of the New York Academy of Sciences. vol 1264. 2012-10-25. PMID:22548651. |
by promoting synaptic plasticity and neurogenesis in the hippocampus, bdnf mediates exercise- and der-induced improvements in cognitive function and neuroprotection. |
2012-10-25 |
2023-08-12 |
Not clear |
| David M Bannerman, Thorsten Bus, Amy Taylor, David J Sanderson, Inna Schwarz, Vidar Jensen, Øivind Hvalby, J Nicholas P Rawlins, Peter H Seeburg, Rolf Sprenge. Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion. Nature neuroscience. vol 15. issue 8. 2012-10-25. PMID:22797694. |
hippocampal nmda receptors (nmdars) and nmdar-dependent synaptic plasticity are widely considered crucial substrates of long-term spatial memory, although their precise role remains uncertain. |
2012-10-25 |
2023-08-12 |
mouse |
| Konstantinos Charizanis, Kuang-Yung Lee, Ranjan Batra, Marianne Goodwin, Chaolin Zhang, Yuan Yuan, Lily Shiue, Melissa Cline, Marina M Scotti, Guangbin Xia, Ashok Kumar, Tetsuo Ashizawa, H Brent Clark, Takashi Kimura, Masanori P Takahashi, Harutoshi Fujimura, Kenji Jinnai, Hiroo Yoshikawa, Mário Gomes-Pereira, Geneviève Gourdon, Noriaki Sakai, Seiji Nishino, Thomas C Foster, Manuel Ares, Robert B Darnell, Maurice S Swanso. Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy. Neuron. vol 75. issue 3. 2012-10-18. PMID:22884328. |
mbnl2 is prominently expressed in the hippocampus and mbnl2 knockouts show a decrease in nmda receptor (nmdar) synaptic transmission and impaired hippocampal synaptic plasticity. |
2012-10-18 |
2023-08-12 |
mouse |
| Tsuyoshi Udagawa, Sharon A Swanger, Koichi Takeuchi, Jong Heon Kim, Vijayalaxmi Nalavadi, Jihae Shin, Lori J Lorenz, R Suzanne Zukin, Gary J Bassell, Joel D Richte. Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex. Molecular cell. vol 47. issue 2. 2012-10-11. PMID:22727665. |
these results identify a pivotal role for polyadenylation and the opposing effects of gld2 and ngd in hippocampal synaptic plasticity. |
2012-10-11 |
2023-08-12 |
Not clear |
| Dmytro Morderer, Oleksii Nikolaienko, Inessa Skrypkina, Volodymyr Cherkas, Liudmyla Tsyba, Pavel Belan, Alla Rynditc. Endocytic adaptor protein intersectin 1 forms a complex with microtubule stabilizer STOP in neurons. Gene. vol 505. issue 2. 2012-10-11. PMID:22750298. |
as stop is a microtubule-stabilizing protein that is required for several forms of synaptic plasticity in the hippocampus, identification of this interaction raises the possibility of itsn1 participation in this process. |
2012-10-11 |
2023-08-12 |
rat |
| Kaori Tachibana, Toshikazu Hashimoto, Rui Kato, Yosuke Uchida, Ryoko Ito, Koichi Takita, Yuji Morimot. Neonatal administration with dexmedetomidine does not impair the rat hippocampal synaptic plasticity later in adulthood. Paediatric anaesthesia. vol 22. issue 7. 2012-10-10. PMID:22309594. |
neonatal administration with dexmedetomidine does not impair the rat hippocampal synaptic plasticity later in adulthood. |
2012-10-10 |
2023-08-12 |
rat |
| Eric C Miller, Lei Zhang, Benjamin W Dummer, Desmond R Cariveau, Horace Loh, Ping-Yee Law, Dezhi Lia. Differential modulation of drug-induced structural and functional plasticity of dendritic spines. Molecular pharmacology. vol 82. issue 2. 2012-10-09. PMID:22596350. |
chronic activation of μ-opioid receptors (mor) in cultured hippocampal neurons causes two forms of synaptic plasticity: loss of dendritic spines and loss of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors. |
2012-10-09 |
2023-08-12 |
Not clear |
| Lian Zhang, Hong-Mei Xiao, Yan-Xia Zhou, Xiao-Ping Lu. Priming stimulation modifies synaptic plasticity in the perforant path of hippocampal slice in rat. Neuroscience bulletin. vol 22. issue 4. 2012-10-02. PMID:17704837. |
priming stimulation modifies synaptic plasticity in the perforant path of hippocampal slice in rat. |
2012-10-02 |
2023-08-12 |
human |
| Michael Foy, Michel Baudry, Richard Thompso. Estrogen and hippocampal synaptic plasticity. Neuron glia biology. vol 1. issue 4. 2012-10-02. PMID:18634593. |
estrogen and hippocampal synaptic plasticity. |
2012-10-02 |
2023-08-12 |
Not clear |
| Michael Foy, Michel Baudry, Richard Thompso. Estrogen and hippocampal synaptic plasticity. Neuron glia biology. vol 1. issue 4. 2012-10-02. PMID:18634593. |
in this review, we examine recent evidence from experimental and clinical research on the rapid effects of estrogen on several mechanisms that involve synaptic plasticity in the nervous system,including hippocampal excitability, long-term potentiation and depression related to sex and aging differences, cellular neuroprotection and probable molecular mechanisms of the action of estrogen in brain tissue. |
2012-10-02 |
2023-08-12 |
Not clear |
| Bai Lu, Jay H Chan. Regulation of neurogenesis by neurotrophins: implications in hippocampus-dependent memory. Neuron glia biology. vol 1. issue 4. 2012-10-02. PMID:18634594. |
neurogenesis is regulated by several extrinsic factors,such as enriched environment, physical exercise, hormones and stress, many of which also induce the expression of neurotrophins.in this review, we summarize studies on the role of neurotrophins in neurogenesis during development and in adults.we discuss the functional significance of neurogenesis in learning and memory, and how neurotrophins regulate this process.in this context, we describe recent experiments linking adult neurogenesis to long-term synaptic plasticity in the hippocampal dentate gyrus. |
2012-10-02 |
2023-08-12 |
Not clear |