| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Zeng, Feng Lv, Long Li, Hui Yu, Min Dong, Qinghai F. 7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats. Journal of neurochemistry. vol 122. issue 4. 2012-09-27. PMID:22694088. |
taken together, our results suggest that 7,8-dhf can act in vivo to counteract aging-induced declines in spatial memory and synaptic plasticity and morphological changes of hippocampal neurons. |
2012-09-27 |
2023-08-12 |
rat |
| Olivier Thibault, Tristano Pancani, Philip W Landfield, Christopher M Norri. Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease. Biochimica et biophysica acta. vol 1822. issue 4. 2012-09-24. PMID:22265986. |
increased function of neuronal l-type voltage-sensitive ca(2+) channels (l-vsccs) is strongly linked to impaired memory and altered hippocampal synaptic plasticity in aged rats. |
2012-09-24 |
2023-08-12 |
mouse |
| C E Stelly, J Cronin, J M Daniel, L A Schrade. Long-term oestradiol treatment enhances hippocampal synaptic plasticity that is dependent on muscarinic acetylcholine receptors in ovariectomised female rats. Journal of neuroendocrinology. vol 24. issue 6. 2012-09-24. PMID:22313316. |
long-term oestradiol treatment enhances hippocampal synaptic plasticity that is dependent on muscarinic acetylcholine receptors in ovariectomised female rats. |
2012-09-24 |
2023-08-12 |
rat |
| C E Stelly, J Cronin, J M Daniel, L A Schrade. Long-term oestradiol treatment enhances hippocampal synaptic plasticity that is dependent on muscarinic acetylcholine receptors in ovariectomised female rats. Journal of neuroendocrinology. vol 24. issue 6. 2012-09-24. PMID:22313316. |
short-term oestradiol treatment modulates hippocampus-dependent memory and synaptic plasticity in the hippocampus. |
2012-09-24 |
2023-08-12 |
rat |
| Ann Van der Jeugd, Katja Hochgräfe, Tariq Ahmed, Jochen M Decker, Astrid Sydow, Anne Hofmann, Dan Wu, Lars Messing, Detlef Balschun, Rudi D'Hooge, Eva-Maria Mandelko. Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau. Acta neuropathologica. vol 123. issue 6. 2012-09-24. PMID:22532069. |
we correlated hippocampal tau pathology with learning/memory performance and synaptic plasticity. |
2012-09-24 |
2023-08-12 |
mouse |
| Francisco J Monje, Eun-Jung Kim, Daniela D Pollak, Maureen Cabatic, Lin Li, Arthur Baston, Gert Lube. Focal adhesion kinase regulates neuronal growth, synaptic plasticity and hippocampus-dependent spatial learning and memory. Neuro-Signals. vol 20. issue 1. 2012-09-20. PMID:21952616. |
a comprehensive study aimed at determining the role of fak in neuronal growth, neurotransmitter release and synaptic plasticity in hippocampal neurons and in hippocampus-dependent learning and memory was therefore undertaken using the mouse model. |
2012-09-20 |
2023-08-12 |
mouse |
| Guoqi Zhu, Yuying Huang, Ying Chen, Yinghan Zhuang, Thomas Behnisc. MPTP modulates hippocampal synaptic transmission and activity-dependent synaptic plasticity via dopamine receptors. Journal of neurochemistry. vol 122. issue 3. 2012-09-20. PMID:22651101. |
mptp modulates hippocampal synaptic transmission and activity-dependent synaptic plasticity via dopamine receptors. |
2012-09-20 |
2023-08-12 |
Not clear |
| Alexander M Kleschevnikov, Pavel V Belichenko, Mehrdad Faizi, Lucia F Jacobs, Khin Htun, Mehrdad Shamloo, William C Moble. Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 27. 2012-09-18. PMID:22764230. |
mouse genetic models of ds exhibit impaired cognition in hippocampally mediated behavioral tasks and reduced synaptic plasticity of hippocampal pathways. |
2012-09-18 |
2023-08-12 |
mouse |
| Li Sui, Yan Wang, Li-Hua Ju, Meng Che. Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex. Neurobiology of learning and memory. vol 97. issue 4. 2012-09-17. PMID:22469747. |
epigenetic mechanisms have recently been known to play fundamental roles in the regulation of synaptic plasticity, and learning and memory tasks in many brain regions, such as the hippocampus, the amygdala, the insular cortex. |
2012-09-17 |
2023-08-12 |
rat |
| Joachim Scholz-Starke, Fabrizia Cesca, Giampietro Schiavo, Fabio Benfenati, Pietro Baldell. Kidins220/ARMS is a novel modulator of short-term synaptic plasticity in hippocampal GABAergic neurons. PloS one. vol 7. issue 4. 2012-09-17. PMID:22563401. |
kidins220/arms is a novel modulator of short-term synaptic plasticity in hippocampal gabaergic neurons. |
2012-09-17 |
2023-08-12 |
mouse |
| Do Young Kim, Junwei Hao, Ruolan Liu, Gregory Turner, Fu-Dong Shi, Jong M Rh. Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis. PloS one. vol 7. issue 5. 2012-09-17. PMID:22567104. |
the kd improved motor disability in the eae model, as well as ca1 hippocampal synaptic plasticity (long-term potentiation) and spatial learning and memory (assessed with the morris water maze). |
2012-09-17 |
2023-08-12 |
mouse |
| R H S Westerink, J P Beekwilder, W J Wadma. Differential alterations of synaptic plasticity in dentate gyrus and CA1 hippocampal area of Calbindin-D28K knockout mice. Brain research. vol 1450. 2012-09-14. PMID:22405690. |
differential alterations of synaptic plasticity in dentate gyrus and ca1 hippocampal area of calbindin-d28k knockout mice. |
2012-09-14 |
2023-08-12 |
mouse |
| R H S Westerink, J P Beekwilder, W J Wadma. Differential alterations of synaptic plasticity in dentate gyrus and CA1 hippocampal area of Calbindin-D28K knockout mice. Brain research. vol 1450. 2012-09-14. PMID:22405690. |
these results support the role of cb as a critical determinant for several forms of synaptic plasticity in hippocampal dg and ca1 area. |
2012-09-14 |
2023-08-12 |
mouse |
| Sylvie Burnouf, Karim Belarbi, Laetitia Troquier, Maxime Derisbourg, Dominique Demeyer, Antoine Leboucher, Cyril Laurent, Malika Hamdane, Luc Buee, David Blu. Hippocampal BDNF expression in a tau transgenic mouse model. Current Alzheimer research. vol 9. issue 4. 2012-09-07. PMID:22272617. |
brain-derived neurotrophic factor (bdnf) is a neurotrophic factor playing a critical role in hippocampal synaptic plasticity and memory and whose levels have been shown reduced in ad brains. |
2012-09-07 |
2023-08-12 |
mouse |
| Clay O Lacefield, Vladimir Itskov, Thomas Reardon, René Hen, Joshua A Gordo. Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus. Hippocampus. vol 22. issue 1. 2012-09-06. PMID:20882540. |
young adult-born neurons exhibit enhanced excitability and have altered capacity for synaptic plasticity in hippocampal slice preparations in vitro. |
2012-09-06 |
2023-08-12 |
mouse |
| Andrea K Titterness, Brian R Christi. Prenatal ethanol exposure enhances NMDAR-dependent long-term potentiation in the adolescent female dentate gyrus. Hippocampus. vol 22. issue 1. 2012-09-06. PMID:21080406. |
these results indicate that prenatal ethanol and prenatal stress produce sex-specific alterations in synaptic plasticity in the adolescent hippocampus. |
2012-09-06 |
2023-08-12 |
Not clear |
| Ami P Raval, Justin T Sick, Gabriel J Gonzalez, R Anthony Defazio, Chuanhui Dong, Thomas J Sic. Chronic nicotine exposure inhibits estrogen-mediated synaptic functions in hippocampus of female rats. Neuroscience letters. vol 517. issue 1. 2012-09-06. PMID:22521583. |
in hippocampus, e₂-signaling regulates synaptic plasticity by phosphorylation of the n-methyl-d-aspartic acid receptor subunit nr2b and cyclic-amp response element binding protein (pcreb). |
2012-09-06 |
2023-08-12 |
rat |
| Gabriele Masi, Paola Brovedan. The hippocampus, neurotrophic factors and depression: possible implications for the pharmacotherapy of depression. CNS drugs. vol 25. issue 11. 2012-09-05. PMID:22054117. |
recent studies indicate that an impairment of synaptic plasticity (neurogenesis, axon branching, dendritogenesis and synaptogenesis) in specific areas of the cns, particularly the hippocampus, may be a core factor in the pathophysiology of depression. |
2012-09-05 |
2023-08-12 |
Not clear |
| Derek A Costello, Marc Claret, Hind Al-Qassab, Florian Plattner, Elaine E Irvine, Agharul I Choudhury, K Peter Giese, Dominic J Withers, Paola Pedarzan. Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity. PloS one. vol 7. issue 2. 2012-08-27. PMID:22383997. |
brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity. |
2012-08-27 |
2023-08-12 |
mouse |
| Derek A Costello, Marc Claret, Hind Al-Qassab, Florian Plattner, Elaine E Irvine, Agharul I Choudhury, K Peter Giese, Dominic J Withers, Paola Pedarzan. Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity. PloS one. vol 7. issue 2. 2012-08-27. PMID:22383997. |
to elucidate the specific role of brain insulin signalling in neuronal functions that are relevant for cognitive processes we have investigated the behaviour of neurons and synaptic plasticity in the hippocampus of mice lacking the insulin receptor substrate protein 2 (irs-2). |
2012-08-27 |
2023-08-12 |
mouse |